Syllabus - UCLA

UNIVERSITY OF CALIFORNIA, LOS ANGELESDepartment of Physiological Science andThe IDP in NeurosciencePS/NS-145/245Winter, 2007Instructor:CourseDescription:Prerequisites:Lecture:Required Text:Neural Mechanisms Controlling MovementDr. Scott H. ChandlerProfessor of Neuroscience and Physiological ScienceDepartment of Physiological ScienceOffice: 2859 Slichter hall Phone: 206-6636; E-mail; schandler@physci.ucla.eduOffice Hours: Mon 3:45 -4:45pm or appt.A cellular and network analysis of the mechanisms responsible for production of movements such aslocomotion and mastication. Students will be introduced to these topics through primary literaturereadings. Class participation is required and a working knowledge of basic cellular neurophysiologyand neuroanatomy will be emphasized.PS-111A/ 180A, or NS101A/, Psych 115, PS 202 (Grad students) or consent of instructorM/W, 11-1pm, LaKrez 120: For graduate students, additional discussion sections are requiredand will be arranged.Course reader is available at Course Reader Materials, 1141 Westwood Blvd. Additionally,materials will be put on our web site.Recommended Text:Any basic Neuroscience textbook such as: D Purves, et al., Neuroscience. Publisher: Sinauer Associates, 2004,2 nd ed or M. Bear et al., Neuroscience, Exploring the Brain. Publisher: Lippincott Williams and Wilkings, 2001.Holiday: Jan 16, Feb 20COURSE OUTLINE (subject to modification)1/8 Introduction and Review: Principles of cellular neurobiology1/10 Factors controlling neuronal discharge: intrinsic membrane properties1/15 Holiday. No Class.1/17 Factors controlling neuronal discharge: synaptic and circuit interactions1/22 Neurobiology of Locomotion: Overview (QUIZ #1 25 Pts)1/24 Introduction to Central Pattern Generator concept1/29 CPG: spinal organization, networks, and models1/31 CPGs: transmitters, pacemaker cells and intrinsic membrane properties2/5 Supraspinal control of locomotion2/7 EXAM (100 pts)2/12 Con’t2/14 Neuronal control of mandibular movement: Introduction and Anatomy of masticatory system2/19 Holiday. No Class2/21 Con’t2/26 Reflex control of mastication (QUIZ #2 25 Pts)2/28 CPG control of mastication: brainstem circuits3/5 Con’t3/7 Neurochemical initiation and control of mandibular movements