Physiological Science 111C: Foundations in Physiological ... - UCLA

Fall Quarter, 2010Instructors:Physiological Science 111C: Foundations in Physiological ScienceTransport, Endocrine and Reproductive PhysiologyProfessor Barney A. SchlingerDepartment of Physiological ScienceTerasaki LSB 2135825-5716Office Hours: Tuesday 10:30 AM -12:00 PM (Oct. 20 - Dec. 3, only)Professor Nasser A. FarahbakhshDepartment of Physiological ScienceLife Sciences 4817206-4343Office Hours: MWF 11:00 AM – 12:00 PM (Sep. 24 - Oct. 18, only)Textbook: Human Physiology, by L. SherwoodStudents will have the option of purchasing lecture notes for transport physiology or downloading themfrom the class website. They will be required to purchase from APS a set of readings for the discussionsections in the second module.Midterms: There will be three midterms: October 18 and November 12, during lecture and the thirdduring Final Exam week. The midterms will last one hour and twenty minutes each and will each comprise25% of the final grade. Note there will be no breaks during the 80 min exams. The first midterm will coverthe material in the first 10 lectures (Transport Physiology); the second midterm will cover the endocrinephysiology (10 lectures); the third midterm will cover all the material on reproductive physiology (8lectures).THERE WILL BE NO MAKE-UP EXAMS. STUDENTS WILL NOT BE PERMITTED TO TAKETHESE EXAMS EARLY OR LATE.Ethics: Any form of cheating will not be tolerated. Students suspected of cheating will be reported tothe Dean of Academic Affairs.Discussion Section (Lab): Attendance in Discussion Sections is required (20 points). Active participationin discussions is also required (30 points). Students will sign up for these sections on the first day of class.The grade for the discussion section will constitute 25% of the final grade.Quizzes and Readings: The remaining 50 points of the grade for the discussion section will be composedof the grade from quizzes, to be given at the beginning of each discussion session based on the followingassigned articles and additional articles to be determined at a later date. There will not be any assignedarticle for Transport Physiology. However, students are expected to read the Supplemental Material(i.e. the material in the notes, but not covered in the lectures), on their own and discuss them, along withthe material covered in lectures, with their TAs, during these sessions.

Week DueOct. 25-29Nov. 1-5Nov. 15-19Nov. 22-26Marx, J. (2003) "Cellular Warriors at the Battle of the Bulge".Science 299: 846- 849Weekes, N. et al. (1998) "Examination stress as an ecological inducer of cortisoland psychological responses to stress in undergraduate students". Stress 8: 199-206.Grinspoon, S. and E. Seely eds. 2006. "Hot topics in pituitary tumor management".Endocrine News 31: 16-21.Aitken et al., 2008 "As the world grows: contraception in the 21 st century". J. Clin.Invest. 118: 1330-1343.SCHEDULE OF LECTURES on Physiology of TransportDatesSep. 24Sep. 27, 29Oct. 1Oct. 4-8Oct. 11-15Oct. 18TOPICSAnatomy of Epithelia. (Supplemental Material: Diffusion of Non-electrolytes andions; Osmosis and the Diffusion of Water; The Donnan Equilibrium).Facilitated Diffusion and Coupled Transport; Symports andAntiports; Active Transport; Polarity and Vectorial Transport; Mechanism ofWater Transport.Mechanism of Water Secretion and Salivary Gland; Secretion by the GastricMucosa of the Stomach; Digestion and Absorption in the Small Intestine;The Kidney: Stucture and Function.The Kidney: The Counter-current Mechanism and Regulation of Osmolality; Acid-Base Balance. Review.First Midterm.