Physiological Science 111B - Foundations in Physiological ... - UCLA

Physiological Science 111BFoundations in Physiological ScienceSpring 2010Course Description: Principles of muscular, cardiovascular and respiratory physiology.http://www.lsic.ucla.edu/classes/spring10/Prerequisites: PS 111A or M180A and Chem 132BLectures MW: 12:00-1:50, FRANZ 1178Instructors: Office Email DatesDr. James Tidball LS 5833 jtidball@physci.ucla.edu March 29-April 19Dr. James Barnard LS 4303A jbarnard@physci.ucla.edu April 21-May 12Dr. Walter Metzner LS 4365 metzner@ucla.edu May 17-June 9Recommended Text: Human Physiology from Cells to Systems by Lauralee Sherwood, 7 th EditionTeaching Assistants:Sean Berquist sberquist@gmail.comShana Dahlan smdahlan@gmail.comMiguel Guiterrez mguti82@ucla.eduMary Leemarymlee@ucla.eduTA Mailboxes: LS 2317Discussion Sections: One, 2hr. meeting each week in LS 2226. Topics of discussion are designed to helpstudents comprehend lecture concepts and will include clarification of lecture material, problem-solving,and/or discussion of original research.Three literature searches will be done on current research and turned in to the TA’s during discussionsections. Failure to turn in a search will result in a 5-point reduction (per search) from the finalscore. At the end of the quarter the points for all exams will be totaled and a curve made to determine thefinal course grade.Examinations:Midterm #1 April 19 Muscular System 125 pointsMidterm #2 May 12 Cardiovascular System 125 pointsMidterm #3 June 9 Respiratory System 125 points1

Lecture Schedule:Date Reading Topic1 st Module: Muscular System - Dr. TidballMarch 29 p. 256-261 Sarcomeres: the contractile units of musclep. 261-264 Molecular motors in muscleMarch 31 p. 272-275 Force, length and velocity relationships in musclep. 264-268 Voluntary contraction of muscleApril 5 p. 276-281 Energy for muscle contractionp. 268-272 Motor units, recruitment and fatigueApril 7 p. 289-299 Smooth muscle and its specializationsApril 12 p. 302-307 Cardiac muscle and its specializationsp. 315-316April 14 none Diversity in muscle form and functionApril 19 1 st Midterm Exam on the Muscular System 12:00-1:502 nd Module: Cardiovascular System - Dr. BarnardApril 21 p. 391-412 Blood components, Hemostasis, Coagulationp. 417-452 Immunological properties of bloodApril 26 p. 303-324 Review of anatomy of the CV systemElectrical activity of the heartECG and cardiac cycleApril 28 p. 325-332 Cardiac outputMay 3Regulation of cardiac performanceMay 5 p. 343-386 Peripheral circulationMay 10 p. 332-337 Coronary blood flow, Cardiovascular diseaseExercise and cardiovascular functionMay 12 2 nd Midterm Exam on the Cardiovascular System 12:00-1:503 rd Module: Respiratory System - Dr. MetznerMay 17 p. 461-472 Structural organization of the respiratory systemVentilation and mechanics of breathingMay 19 p. 472-485 Elastic properties of the lungHow to measure pulmonary functionMay 24 p. 486-496 Diffusion of gas across gas-blood barrierBlood gas transportMay 26 p. 498-505 Control of breathing: central-nervous, reflex, andchemoreceptorsMay 31 Memorial Day HolidayJune 2 p. 569-585 Acid-base regulationp. 496-498 Breathing in unusual environmentsWed, 09 June 09; 3:00 PM - 6:00 PM 3 rd Midterm Exam on the Respiratory SystemPlease note that the final exam (3 rd MT) is non-cumulative and covers only the respiratory portion.2