Creative Biolabs Announced Anti-idiotypic Antibody
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<strong>Creative</strong> <strong>Biolabs</strong> <strong>Announced</strong> <strong>Anti</strong>-<strong>idiotypic</strong> <strong>Anti</strong>body<br />
<strong>Creative</strong> <strong>Biolabs</strong> is a manufacturer of various antibody products.<br />
To meet the need in pre-clinical study of therapeutic antibody and vaccine<br />
development, <strong>Creative</strong> <strong>Biolabs</strong> expanded its antibody category and launched<br />
anti-<strong>idiotypic</strong> antibody products for various applications, such as pharmacokinetic<br />
study, neutralizing antibody study and immunogenicity study.<br />
<strong>Anti</strong>-<strong>idiotypic</strong> antibody (anti-ID antibody) is a class of antibody that specifically<br />
binds to the antigen-binding site of an antibody. For each antibody molecule, the<br />
region that makes contact with an antigen is called complementary determining region<br />
(CDR) which is a unique site to be found within the variable (V) regions of an<br />
antibody heavy chain and light chain. The term idiotype refers to the whole collection<br />
of idiotopes contained in a single immunoglobulin molecule. Idiotopes may be either<br />
in the CDR or in the framework regions (FR) of the variable domain. Therefore,<br />
depending on the binding area within the immunoglobulin molecules, <strong>Creative</strong><br />
<strong>Biolabs</strong>’ anti-ID antibodies can be classified into four distinct types as follows, Type I<br />
anti-ID, of which the target idiotope is within CDR, Type II anti-ID, of which the<br />
target idiotope is within FR, Type III anti-ID, which may partially block Ag-Ab<br />
interaction and Type IV anti-ID, which recognizes both idiotope of antibody and<br />
epitope of the antigen.<br />
As a pioneer in antibody development and production in full range of applications, it<br />
committed to provide full range of anti-ID antibody products of high-quality for using<br />
in different area. Beyond an increasing number of our anti-ID antibody products,<br />
comprehensive anti-ID antibody custom service is also available for clients to choose<br />
for their researches.<br />
About <strong>Creative</strong> <strong>Biolabs</strong><br />
Over the last 10 years, <strong>Creative</strong> <strong>Biolabs</strong> has been a leader of recombinant antibody<br />
(rAb) discovery and manufacturing, providing high quality service to customers in<br />
academia and industry fields all over the world.<br />
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