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Creative Biolabs Announced Anti-idiotypic Antibody

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<strong>Creative</strong> <strong>Biolabs</strong> <strong>Announced</strong> <strong>Anti</strong>-<strong>idiotypic</strong> <strong>Anti</strong>body<br />

<strong>Creative</strong> <strong>Biolabs</strong> is a manufacturer of various antibody products.<br />

To meet the need in pre-clinical study of therapeutic antibody and vaccine<br />

development, <strong>Creative</strong> <strong>Biolabs</strong> expanded its antibody category and launched<br />

anti-<strong>idiotypic</strong> antibody products for various applications, such as pharmacokinetic<br />

study, neutralizing antibody study and immunogenicity study.<br />

<strong>Anti</strong>-<strong>idiotypic</strong> antibody (anti-ID antibody) is a class of antibody that specifically<br />

binds to the antigen-binding site of an antibody. For each antibody molecule, the<br />

region that makes contact with an antigen is called complementary determining region<br />

(CDR) which is a unique site to be found within the variable (V) regions of an<br />

antibody heavy chain and light chain. The term idiotype refers to the whole collection<br />

of idiotopes contained in a single immunoglobulin molecule. Idiotopes may be either<br />

in the CDR or in the framework regions (FR) of the variable domain. Therefore,<br />

depending on the binding area within the immunoglobulin molecules, <strong>Creative</strong><br />

<strong>Biolabs</strong>’ anti-ID antibodies can be classified into four distinct types as follows, Type I<br />

anti-ID, of which the target idiotope is within CDR, Type II anti-ID, of which the<br />

target idiotope is within FR, Type III anti-ID, which may partially block Ag-Ab<br />

interaction and Type IV anti-ID, which recognizes both idiotope of antibody and<br />

epitope of the antigen.<br />

As a pioneer in antibody development and production in full range of applications, it<br />

committed to provide full range of anti-ID antibody products of high-quality for using<br />

in different area. Beyond an increasing number of our anti-ID antibody products,<br />

comprehensive anti-ID antibody custom service is also available for clients to choose<br />

for their researches.<br />

About <strong>Creative</strong> <strong>Biolabs</strong><br />

Over the last 10 years, <strong>Creative</strong> <strong>Biolabs</strong> has been a leader of recombinant antibody<br />

(rAb) discovery and manufacturing, providing high quality service to customers in<br />

academia and industry fields all over the world.<br />

http://www.abnewswire.com/adminpreview.php?id=u0Kllfd

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