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What You Need to Know About Monoclonal Canine (Dog) Antibody

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<strong>What</strong> <strong>You</strong> <strong>Need</strong> <strong>to</strong> <strong>Know</strong> <strong>About</strong> <strong>Monoclonal</strong> <strong>Canine</strong> (<strong>Dog</strong>) <strong>Antibody</strong><br />

<strong>Dog</strong>s are the first domesticated animals that have been widely kept as working,<br />

hunting, and pet companions. According <strong>to</strong> recent coarse estimates, there are currently<br />

between 700 million and one billion dogs, making them the most abundant preda<strong>to</strong>rs<br />

in the world. We human beings regard dogs as our best friends. Thus, <strong>to</strong> protect dogs,<br />

our friends, from diseases should be listed among the catalogue of biopharmaceutical<br />

research.<br />

<strong>Antibody</strong> phage display, especially monoclonal antibody phage display, is commonly<br />

used in disease prevention and treatment. However, when it comes <strong>to</strong> monoclonal<br />

canine antibody, not much information could be offered. Creative Biolabs, fortunately,<br />

is an exceptional.<br />

As a recognized leader in the fields of phage display and antibody engineering,<br />

Creative Biolabs is specialized in phage display antibody library technology <strong>to</strong> make<br />

monoclonal rabbit, chicken, llama, dog, monkey, mouse and human antibodies.<br />

Particularly, they are proud <strong>to</strong> be the first and the only company <strong>to</strong> provide<br />

monoclonal canine antibody generation services.<br />

Based on their extensive experiences in phage display library construction and<br />

screening, scientists in Creative Biolabs have created several immunized canine<br />

antibody libraries, from which they have successfully isolated a number of high<br />

affinity antibodies using panning techniques. Through this strategy, they can generate<br />

cus<strong>to</strong>m monoclonal canine antibodies that have the potential <strong>to</strong> be used in a wide<br />

range of biomedical applications, including the treatment of malignant, infectious,<br />

inflamma<strong>to</strong>ry and au<strong>to</strong>immune diseases in dogs, which pave the way for exploration<br />

of such applications in canine medicine.<br />

As for antigens that are not suitable for immunization, Creative Biolabs are also<br />

pleased <strong>to</strong> make a cus<strong>to</strong>m synthetic canine antibody library for you based on our full<br />

understanding of the canine antibody reper<strong>to</strong>ires. They can take the major framework<br />

sequence of light chain heavy chain of canine antibody reper<strong>to</strong>ires and then create<br />

mutations or variations in all 6 CDR regions (or 2 CDR3 regions). Combined with<br />

various mutation strategies, thay can produce canine antibodies against any antigens,<br />

including those that are <strong>to</strong>xic and of no immune response in animals.<br />

Apart from developing monoclonal canine antibodies, Creative Biolabs also<br />

established a platform for monoclonal antibody caninization, murinization and<br />

humanization services.<br />

Learn more <strong>Monoclonal</strong> <strong>Canine</strong> (<strong>Dog</strong>) <strong>Antibody</strong> Production from Creative Biolabs.<br />

<strong>About</strong> Creative Biolabs


Creative Biolabs Creative Biolabs is specialized in providing cus<strong>to</strong>m biotechnology<br />

and pharmaceutical services that cover the full scope of biotechnology needs of early<br />

drug discovery and drug development. As a trusted provider of the most cost-effective<br />

outsourcing solutions, Creative Biolabs has been working for a large number of<br />

satisfied clients from biotechnology and pharmaceutical companies as well as<br />

government and academic research labora<strong>to</strong>ries all over the world.

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