197824324

SUMMARY
„Frequency of extraintestinal manifestations of inflammatory bowel disease in children.“,Edita
Brezovec.
Inflammatory bowel diseases are the most common and most significant chronic disorders
in pediatric gastroenterology. They are not just a disorder of one organ system, but a multisystemic
diseases. Inflammatory bowel disease together with medications that are used and other medical or
surgical interventions can have adverse effects on linear growth, pubertal development and nutritional
status. It has been estimated that approximately 25% of all new patients with inflammatory bowel
disease are diagnosed before 20 years of age and 35% of them will be presented during their lifetime
with at least one extraintestinal manifestations (1,2). Intestinal manifestations are most commonly
manifested as abdominal pain, weight loss, diarrhea, a palpable abdominal mass, hematochezia and
appearance of perianal fistulae or abscesses On the other hand, extraintestinal manifestations may
involve skin, joints, eyes respiratory and hepatobiliary systems, as well as increased risk for venous
thrombosis. It is important to be aware of exstraintesinal manifestations because it could be the first
presentation of the disease even before gastrointestinal symptoms develop. It is important to
emphasize that extraintestinal manifestations do not consistently correlate with the degree of intestinal
inflammation but if they occur together with the intestinal disease, then they will increase mortality in
this children. Inflammatory bowel disease can also contribute to a greater risk for the development of a
variety of psychosocial problems. All these mentioned problems can interfere with their ability to
participate in their daily life activities.
The aim oft this review is to inform clinicans about the frequency of exstraintestinal
manifestations in the pediatric population and to describe some of the features of inflammatory bowel
disease unique to this population. These features could potentially have a significant impact both in the
further research as well as clinical management of patients with inflammatory bowe diseases.
Keywords: exstraintestinal manifestation, pediatric population, frequency