Wien, 28 - Repository of the LBI-HTA - Ludwig Boltzmann Gesellschaft

Author, year, reference
number
Tumor location, n
(several tumors/
patient)
Radiofrequenzablation bei Tumoren des Urogenitaltrakts
(Nierenzellkarzinom, Prostatakarzinom, Leiomyome des Uterus)
Meng (2010) [39] Garza Leal (2011) [43] Lee (2010) [40] 10 Cho (2008) [44] 8 Ghezzi (2007) [42] Kim (2007) [41]
I vs C:
intramural (46 vs 45)
submucosal (9 vs 16)
subserosal (15 vs 7)
Tumor size (cm) I vs C:
O/5±1 (range 2-8) vs
O/5±1 (range 2-8)
Follow-up
(months)
Loss to followup,
n (%)
submucosal 8
intramural 46
subserosal 22
submucosal leiomyoma in
all pts
range 1-10 O/5±2 (range 3-8) O/5±2
(initial size of dominant
myoma)
n/a - of dominant myoma:
posterior 12 (48%)
anterior 9 (36%)
fundal 4 (16%)
median 5 (range 3-9)
(initial size of dominant
myoma)
subserosal and/or
intramural uterine leiomyoma in all pts
n/a 12 6 18 median 24
(range 12-36)
6
n/a 12/31 (39) at 12 months 0 14/153 (9) 16/25 (64) at 36 months 0
Outcome
Efficacy
Tumor/uterine - complete ablation: - uterine volume (cm
volume reduction RFA: in 45/50 pts (90%)
HIFU: in 29/50 pts
(58%)
3 ):
O/194±106 preoperative vs
O/113±54 at 12 months, (in
19/31 (61%) of pts),
P=0.006
- reduction rate of uterine
volume: 74% (14/19 pts) at
12 months
Quality of life
score11 (baseline
n/a O/60±23 vs
O/98±3 at 12 months,
vs postoperative)
P