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A SHORT COURSE IN THE MODELING OF CHEMOTAXIS

A SHORT COURSE IN THE MODELING OF CHEMOTAXIS

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(v) The system is closed so that neither bacteria nor substrate enter (exit) through<br />

the boundaries.<br />

We can write the system of equations 8 (in the same fashion as done in section 2.1)<br />

as<br />

∂b<br />

∂t<br />

∂s<br />

∂t<br />

�<br />

∂<br />

= µ(s)<br />

∂x<br />

∂b<br />

�<br />

∂s<br />

− bχ(s)<br />

∂x ∂x<br />

17<br />

(2.10)<br />

= −k(s)b (2.11)<br />

for t > 0 and 0 < x < L (L=length of capillary tube), and with the conditions<br />

s(x, 0) = s0(x), b(x, 0) = b0(x),<br />

∂b<br />

∂x<br />

= ∂s<br />

∂x<br />

= 0 when x = 0, L.<br />

The no flux conditions are because of assumption (v), and s0 and b0 are given initial<br />

distributions of substrate and bacteria, respectively. Since the focus of this study is<br />

to determine if traveling waves can be observed, and since the length of the capillary<br />

tube is considered to be very large in comparison to a bacterial band, the analysis<br />

is facilitated by introducing a traveling wave coordinate and extending the domain<br />

of interest to the whole real line. That is, let<br />

z = x − ct − ∞ < z < ∞, b(x, t) = b(z), and s(x, t) = s(z)<br />

Further assume that k, µ, and s0 are constant and that in the far field s = s0. In<br />

the variable z the system (2.10)–(2.11) becomes 9<br />

cb ′ = −µb ′′ + (bχ(s)s ′ ) ′<br />

(2.12)<br />

cs ′ = −kb (2.13)<br />

8 Observe that in this one space dimension setting the operator ∇ = ∂<br />

∂x .<br />

9 ′ ≡ d<br />

dz

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