The role of eNOS, iNOS and NFκB in upregulation and activation of ...
The role of eNOS, iNOS and NFκB in upregulation and activation of ...
The role of eNOS, iNOS and NFκB in upregulation and activation of ...
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Ye Y, et al. Mechanisms <strong>of</strong> COX2 <strong>upregulation</strong> by atorvastat<strong>in</strong> 28<br />
Figure 5: Immun<strong>of</strong>luorescent sta<strong>in</strong><strong>in</strong>g <strong>of</strong> NF B <strong>in</strong> heart tissue <strong>of</strong> WT mice not receiv<strong>in</strong>g<br />
(ATV-) or receiv<strong>in</strong>g (ATV+) ATV. <strong>The</strong> nuclei are sta<strong>in</strong>ed <strong>in</strong> blue (DAPI) <strong>and</strong> NF B p65<br />
<strong>in</strong> red. Translocation <strong>of</strong> NF B <strong>in</strong>to the nuclei is seen <strong>in</strong> the ATV treated mice.<br />
Figure 6: Myocardial COX2, <strong>iNOS</strong>, I B <strong>and</strong> -act<strong>in</strong> levels <strong>and</strong> nuclear p-STAT-1 <strong>and</strong><br />
Lam<strong>in</strong> B levels <strong>in</strong> mice treated with <strong>in</strong>traperitoneal ATV alone or with AG490 (a JAK<br />
<strong>in</strong>hibitor) or SN50 (an NF B <strong>in</strong>hibitor). * p
Change language