SATS 2009 Final Program - Scandinavian Association for Thoracic ...
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<strong>Final</strong> <strong>Program</strong>me & Abstracts<br />
First Joint <strong>Scandinavian</strong> Conference<br />
in Cardiothoracic Surgery<br />
The 58 th Annual Meeting of the <strong>Scandinavian</strong> <strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery (<strong>SATS</strong>)<br />
The 29 th Annual Meeting of The <strong>Scandinavian</strong> Society of Extra Corporeal Technology (SCANSECT)<br />
The 2 nd Annual Meeting of The <strong>Scandinavian</strong> Associaton of <strong>Thoracic</strong> Nurses (SATNU)<br />
The annual meetings <strong>for</strong> The Swedish <strong>Association</strong> <strong>for</strong> Cardiothoracic Surgery and<br />
The Swedish <strong>Association</strong> <strong>for</strong> Cardiothoracic Anesthesiology and Intensive Care<br />
STOCKHOLM August 20-22 <strong>2009</strong><br />
www.sats<strong>2009</strong>.org
Organisation<br />
Organizing Committee Scientific Committees<br />
Dan Lindblom (chairman, surgeon)<br />
<strong>SATS</strong><br />
Jan Hultman (Conference president, anesthesiologist)<br />
Ulf Lockowandt (surgeon)<br />
Sten Samuelsson (anesthesiologist)<br />
Anders Albåge (surgeon)<br />
Jan van der Linden (anesthesiologist)<br />
Ulrik Sartipy (surgeon)<br />
SCANSECT<br />
Per Stensved (president of SCANSECT)<br />
Conny Rundby<br />
Pia Vanhanen<br />
SATNU<br />
Susann Edvinsson Larsson (president of SATNU, OR)<br />
Birgitta Martinsson (anest.)<br />
Jennie Sandberg (ICU)<br />
Sofia Lorentzi (ward)<br />
PHYSIOTHERAPISTS SESSION<br />
Ulrika Thunström<br />
<strong>SATS</strong><br />
Timo Savunen (Secretary general, surgeon)<br />
Anders Jeppsson (surgeon)<br />
Daniel Steinbrüchel (surgeon)<br />
Odd Geiran (surgeon)<br />
Jari Laurikka (surgeon)<br />
Tómas Guðbjartsson (surgeon)<br />
Jan van der Linden (anesthesiologist)<br />
Knut Kirkebøen (anesthesiologist)<br />
SCANSECT<br />
Anne Louise Bellaiche (chairperson)<br />
Micael Appelblad<br />
Vivian Høyland<br />
Líney Símonardóttir<br />
Peter Fast Nielsen<br />
SATNU<br />
Marita Ritmala-Castrén (chairperson)<br />
Gunilla Barr<br />
Liselotte Brahe<br />
Kari Hanne Gjeilo
Table of contents<br />
Awards. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 06<br />
<strong>Program</strong>me Overview . . . . . . . . . . . . . . . . . . . . . . . 07<br />
Scientific <strong>Program</strong>me . . . . . . . . . . . . . . . . . . . . . . . 11<br />
Invited Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . 18<br />
Registration and hotel accommodation ..........18<br />
Social <strong>Program</strong>me ..........................20<br />
General in<strong>for</strong>mation .........................22<br />
Transportation .............................23<br />
Visiting Stockholm ..........................24<br />
Kistamässan Overview . . . . . . . . . . . . . . . . . . . . . . 26<br />
Exhibition .................................28<br />
Sponsors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30<br />
Author's Index .............................31<br />
Abstracts .................................37<br />
Conference and Exhibition Secretariat<br />
MCI Stockholm Office<br />
P.O. Box 6911<br />
SE-102 39 Stockholm, Sweden<br />
Phone: + 46 8 5465 1500<br />
Fax: +46 8 5465 1599<br />
E-mail: confirmation-sweden@mci-group.com<br />
All correspondence to the Organizing Committee may be sent to the Conference secretariat <strong>for</strong> further distribution.<br />
STOCKHOLM, SWEDEN 3<br />
Stockholm Visitors Board - Olof Holdar
Dear Friends and Colleagues<br />
On behalf of <strong>SATS</strong>, it is a pleasure and privilege to welcome you to the annual <strong>SATS</strong>, SCANSECT<br />
and SATNU meeting in Stockholm, August 20-22.<br />
We are proud to present this event as the<br />
“First Joint <strong>Scandinavian</strong> Conference in Cardiothoracic Surgery”<br />
In modern cardiothoracic surgery the importance of the teamwork approach is evident. Accordingly,<br />
we have tried to make the programme interesting <strong>for</strong> all attendants regardless of field of expertise<br />
in cardiothoracic surgery and its clinical challenges. The national and international response to this<br />
approach has been good. This year we welcome an unusually large number of anesthesiologists<br />
to the meeting and the number of nurses has more than doubled since last year. In addition we<br />
welcome a group of physiotherapists with a special interest in cardiothoracic surgery. The large<br />
number of participants is probably also a result of this conference being a joint venture with<br />
the Swedish <strong>Association</strong>s <strong>for</strong> Cardiothoracic Surgery and Cardiothoracic Anaesthesiology and<br />
Intensive Care. Consequently we should have enough prerequisites <strong>for</strong> interesting discussions<br />
among delegates with different experiences and approaches to everyday clinical issues in the<br />
fascinating, complicated and developing field of cardiothoracic surgery.<br />
We have been very <strong>for</strong>tunate in attracting well-known international lecturers in all topics of the meeting.<br />
Just in mentioning the main topics I would like to express special thanks to Prof. Gerald Buckberg and<br />
Prof. Anelechi Anyanwu, who will take part in The Right Heart topic on Thursday. For the second main<br />
topic on Saturday Prof. Ottavio Alfieri and Francesco Maisano, will guide us through the evolving<br />
Transcatheter Techniques <strong>for</strong> Heart Valve Diseases.<br />
Apart from the scientific programme I hope you all will find the social programme attractive.<br />
Stockholm has a lot to offer and I think all of you will enjoy the city. With all the respect to our Italian<br />
colleagues, Stockholm is sometimes referred to as “The Venice of the North”. True or not, there is<br />
plenty of water in and around the city and it’s clean enough <strong>for</strong> a swim.<br />
The Organizing Committee at The Department of Cardiothoracic Surgery and Anaesthesiology,<br />
Karolinska University Hospital, has done a great job in making this event possible. In this I would<br />
like to thank all colleagues <strong>for</strong> their contributions. Many thanks to the MCI group here in Stockholm,<br />
a true professional Congress Organizer. Also special thanks to the generosity from sponsors of the<br />
conference.<br />
Once more, welcome to the "First Joint <strong>Scandinavian</strong> Conference in Cardiothoracic Surgery" in<br />
Stockholm, August 20-22, <strong>2009</strong><br />
Jan Hultman<br />
Conference President<br />
4 www.sats<strong>2009</strong>.org
Transcatheter<br />
Valve<br />
CardioVascular. Innovation through Collaboration.<br />
Ventor valve is not approved yet and still under clinical trial.<br />
UC201001044EE
Awards<br />
<strong>SATS</strong><br />
C.W.Lillehei Young Investigators Award<br />
Sponsored by St. Jude Medical, the prize of USD 5000 is given to the best young investigator abstract, according<br />
to a decision of the board of <strong>SATS</strong> scientific committee.<br />
The Karl Victor Hall Award<br />
Sponsored by Medtronic, the prize of USD 5000 is given to the best abstract. Candidates may be members or nonmembers<br />
of <strong>SATS</strong>, but the author should have Nordic nationality or residency in a Nordic country. The selection is<br />
made by the board of <strong>SATS</strong> scientific committee.<br />
SCANSECT<br />
Medtronic Best Perfusionist Paper Presentation Award<br />
This is the prize <strong>for</strong> the best perfusionist paper presentation. The award is of €1000 and is sponsored by Medtronic.<br />
Sorin Group Best First Time Perfusionist Presenter Award<br />
This prize is awarded the best presentation by a perfusionist who presents <strong>for</strong> the first time at an international<br />
meeting. The award is of €500 and is sponsored by the Sorin Group.<br />
SCANSECT Best Perfusion School Graduation Paper Presentation Award<br />
This prize is awarded a perfusionist <strong>for</strong> the best school graduation paper presentation. The award is of €500 and is<br />
sponsored by SCANSECT.<br />
Maquet Best Case Report Presentation Award<br />
This is the award <strong>for</strong> the best case-report presented by a perfusionist. The award is of €500 and is sponsored by<br />
Maquet Cardiopulmonary.<br />
Terumo Best Perfusion Poster Presentation Award<br />
This is awarded <strong>for</strong> the best poster presented by a perfusionist. The award is of €300 and is sponsored by Terumo.<br />
SATNU<br />
Mölnlycke Best Nursing Speaker/Poster Travel Award<br />
Given <strong>for</strong> the best speaker/poster presented by a nurse. The travel award is SEK 5000 and is sponsored by Mölnlycke.<br />
ADDITIONAL AWARDS<br />
In addition to these <strong>Scandinavian</strong> awards there are also some awards specific <strong>for</strong> the Swedish <strong>Association</strong>s of<br />
Cardiothoracic Surgery and Cardiothoracic Anesthesiology and Intensive Care.<br />
• Edwards Life-Sciences travelling grant on SEK 15000 <strong>for</strong> education in valve surgery<br />
• Octopus Limedic travelling grant on SEK 15000 <strong>for</strong> best presentation at the meeting<br />
• Orion Pharma´s award on SEK 15000 <strong>for</strong> the best anesthesiological presentation<br />
• “Cardiothoracic Anesthesiologist of the year” – an award on SEK 5000 from the Swedish <strong>Association</strong> <strong>for</strong><br />
Cardiothoracic Anesthesiology and Intensive Care<br />
6 www.sats<strong>2009</strong>.org
<strong>Program</strong>me overview<br />
Thursday, 20 August <strong>2009</strong><br />
SCANSECT SATNU Physiotherapists<br />
<strong>SATS</strong><br />
Opening ceremony and Welcome<br />
13:00-13:30<br />
Timo Savunen, Secretary General <strong>SATS</strong><br />
Jan Hultman, Conference President<br />
Per Stensved, President SCANSECT <strong>2009</strong><br />
Susann Edvinsson Larsson, President SATNU<strong>2009</strong><br />
Main topic 1: The Right heart<br />
Moderators: Ulf Lockowandt and Anders Jeppsson<br />
Speakers:<br />
Gerald Buckberg; The Right Ventricle; from Structure to Function<br />
Jan Hultman; Evaluation of Right Ventricular Function<br />
Lars Algotsson; Peri- and Post-operative Right Ventricular Failure<br />
Anelechi Anyanwu; Surgery <strong>for</strong> Functional Tricuspid Regurgitation<br />
13:30-15:30<br />
Pause; visit the exhibition!<br />
15:30-16:15<br />
Introduction of the <strong>2009</strong> Clarence Crafoord lecturer<br />
Lars Wiklund, Chairman of the Swedish <strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery<br />
<strong>2009</strong> Clarence Crafoord lecture<br />
Professor Gerald Buckberg, UCLA<br />
A Unifying Geometric Approach to Dilated Cardiomyopathy from Many Causes<br />
STOCKHOLM, SWEDEN 7<br />
16:15-16:30<br />
16:30-17:30<br />
Gala Dinner at Solliden, Skansen<br />
19:30<br />
Individual transportation
<strong>Program</strong>me overview<br />
Friday, 21 August <strong>2009</strong><br />
<strong>SATS</strong><br />
SCANSECT SATNU Physiotherapists<br />
08:30-13:00 08:30-10:00<br />
08:30-10:15 08:30-10:00 08:30-09:00<br />
Oral abstract session<br />
Symposium; Weaning from long- Oral abstract session Introduction<br />
Moderators: Eva Berglin and Jan van der Linden<br />
term assist devices Moderators: Moderators: Unni Kleppe Ulrika Thunström<br />
Six abstracts nominated <strong>for</strong> the C.W Lillehei and K.V.Hall awards Laila Hellgren-Johansson and Haukeland and Marita 09:00-09:45<br />
Peter Svenarud Speakers: Lars Ritmala-Castren<br />
National guidelines <strong>for</strong><br />
Lund, Asghar Khaghani , Conny 10:00-10:30<br />
chest physiotherapy<br />
Rundby, Maria Eriksson<br />
Invited lecture<br />
Charlotte Urell<br />
Waiting <strong>for</strong> heart surgery 9:45-10:30<br />
Bodil Ivarsson<br />
Current practice <strong>for</strong><br />
Introduced by Gunilla Barr chest physiotherapy<br />
Elisabeth Westerdahl<br />
Pause 10:00-10:20<br />
Pause 10:15-10:45<br />
Pause 10:30-11:00 Pause 10:30-11:00<br />
10:20-11:30 10:45-13:00 11:00-13:00 11.00-11.30<br />
Oral abstract session (Cardiac)<br />
Oral abstract session<br />
Oral abstract session Smärta, lungfunktion<br />
Moderators: Odd Geiran and Åsa Haraldsson<br />
Moderators: Per Stensved and Moderators: Anita Tracey och opiater<br />
Else Nygren<br />
and Lotte Brahe<br />
Maria Antonsson<br />
Introduced by Sofia<br />
Pause 11:30-11:50<br />
Broman<br />
11:50-13:00 11:50-13:00<br />
Oral abstract session<br />
Oral abstract session (Basic<br />
(Cardiothoracic) Moderators: science) Moderators: Gabriella<br />
Tómas Guðbjartsson and Kristiina Lindvall and Ulrik Sartipy<br />
Hersio<br />
8 www.sats<strong>2009</strong>.org<br />
13:00-14:15<br />
Lunch, visit the exhibition!<br />
Symposium; Humanitarian Work in Cardiac Surgery<br />
Moderators: Dan Lindblom and Eva Ahlgren<br />
Speakers:<br />
Stefan Peterson; Impact of Cardiovascular Diseases in Developing Countries<br />
Sylvain Chauvaud; Experiences by Chaine de l´espoir<br />
Gino Strada; Experiences by Emergency<br />
Coffee; visit the exhibition!<br />
14:15-15.45<br />
Exchange of<br />
experiences<br />
Moderators; Ulrika<br />
Thunström and Sofia<br />
Broman<br />
Invited lecture<br />
Psychosocial aspects of<br />
heart failure<br />
Anna Strömberg<br />
Introduced by Anita Tracey<br />
Invited Lecture;<br />
Long Term Assist Devices<br />
previous, current and <strong>for</strong>ecast<br />
Heinz-Hermann Weitkemper<br />
Introduced by Anne-Louise<br />
Bellaiche<br />
15:45-16:15<br />
16:15-17:15 Invited Lecture<br />
Critically Interpreting the<br />
mitral literature<br />
Anelechi Anyanwu<br />
Introduced by Sten Samuelsson<br />
Awards and pre-dinner party<br />
17:30-18:45<br />
Buses leave from Kista-mässan<br />
Buffet dinner at the Stockholm City Hall<br />
Steamboat tour in the Stockholm Archipelago<br />
18:45<br />
19:30<br />
21:15
Saturday, 22 August <strong>2009</strong><br />
<strong>SATS</strong><br />
SCANSECT SATNU Physiotherapists<br />
08:30-10:00 Cardiogenic shock in myocardial Infarction<br />
Invited lecture Oral abstract<br />
Moderators; Anders Albåge and Jan Hultman<br />
Reducing VAP session<br />
Speakers:<br />
in the ICU Moderator;<br />
Lars Lund; Background and Current Guidelines <strong>for</strong> Intervention<br />
Eva Joelsson Alm Gun Faager<br />
Lars Wiklund; Revascularization and Other Surgical Options<br />
Introduced by Gunilla Barr<br />
Asghar Khaghani; Mechanical support<br />
General assembly<br />
10:00-10:30 General assembly<br />
General assembly<br />
09:30-10:30<br />
10:30-11:00<br />
Pause; vixit the exhibition!<br />
11:00-13:00<br />
Main topic 2; Transcatheter Valve Techniques<br />
Moderator: Anders Jönsson<br />
History and Future of Aortic Valve Implantation<br />
Speaker: Ottavio Alfieri<br />
Invited discussant: Kenneth Pehrsson<br />
History and Future of Mitral Valve Interventions<br />
Speaker: Francesco Maisano<br />
Invited discussant: Reidar Winter<br />
13:00-13:15<br />
Closing remarks<br />
Jan Hultman<br />
15:00-16:00 Visit at Karolinska. Contact<br />
Susann Edvinsson Larsson<br />
(susann.edvinssonlarsson@satnu.org)<br />
if you<br />
are interested<br />
STOCKHOLM, SWEDEN 9
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Scientific <strong>Program</strong>me<br />
THURSDAY, 20 AUGUST <strong>2009</strong><br />
13:00 - 13:30 Opening Ceremony Lecture room M2<br />
Welcome<br />
Timo Savunen, Secretary General <strong>SATS</strong><br />
Jan Hultman, Conference President<br />
Per Stensved, President SCANCSECT <strong>2009</strong><br />
Susann Edvinsson Larsson, President SATNU <strong>2009</strong><br />
13:30 - 15:30 Main topic 1: The Right heart Lecture room M2<br />
Moderators: Ulf Lockowandt and Anders Jeppsson<br />
Speakers:<br />
Gerald Buckberg; The Right Ventricle; from Structure to Function<br />
Jan Hultman; Evaluation of Right Ventricular Function<br />
Lars Algotsson; Peri- and Post-operative Right Ventricular Failure<br />
Anelechi Anyanwu; Surgery <strong>for</strong> Functional Tricuspid Regurgitation<br />
15:30 - 16:15 Pause; visit the exhibition!<br />
16:15 - 16:30 Introduction of the <strong>2009</strong> Clarence Crafoord lecturer Lecture room M2<br />
Lars Wiklund, Chairman of the Swedish <strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery<br />
16:30 - 17:30 <strong>2009</strong> Clarence Crafoord lecture Lecture room M2<br />
Professor Gerald Buckberg, UCLA<br />
A Unifying Geometric Approach to Dilated Cardiomyopathy from Many Causes<br />
19:30 Gala Dinner at Solliden, Skansen<br />
Individual transportation.<br />
STOCKHOLM, SWEDEN 11<br />
www.exigus.se
FRIDAY, 21 AUGUST <strong>2009</strong><br />
08:30 - 10:00 S01 <strong>SATS</strong> Award nominees’ Oral abstract session Lecture room M1<br />
Moderators: Eva Berglin and Jan van der Linden<br />
Six abstracts nominated <strong>for</strong> the C.W Lillehei and K.V.Hall awards<br />
08:30 - 08:45 S01:1 Impact of Papillary Muscle Relocation as Adjunct Procedure to Mitral Ring Annuloplasty in<br />
Functional Ischemic Mitral Regurgitation<br />
Henrik Jensen, Morten Jensen, Morten Smerup, Per Wierup, Steffen Ringgaard,<br />
J. Michael Hasenkam, Sten Lyager Nielsen, Denmark<br />
08:45 - 09:00 S01:2 Aprotinin reduces the antiplatelet effect of clopidogrel.<br />
Gabriella Lindvall, Ulrik Sartipy, Staffan Bjessmo, Peter Svenarud, Bo Lindvall,<br />
Jan van der Linden, Sweden<br />
09:00 - 09:15 S01:3 30-day outcomes in high risk-patients randomized to off-pump or on-pump<br />
coronary bypass Surgery<br />
Christian H Møller, Mario Perko, Jens Lund, Lars W. Andersen, Jan K. Madsen,<br />
Christian Gluud, Daniel A. Steinbrüchel, Denmark<br />
09:15 - 09:30 S01:4 Catheter based aortic valve implantation – results from the first 50 patients<br />
Hans Henrik Møller Nielsen, Leif Thuesen, Henning Rud Andersen, Vibeke E Hjortdal,<br />
Kaj-Erik Klaaborg, Carl-Johan Jakobsen, Ingeborg Böing, Denmark<br />
09:30 - 09:45 S01:5 The New TNM Staging System <strong>for</strong> Lung Cancer - A Review of 511 patients operated at<br />
Karolinska University Hospital.<br />
Per Bergman, Daniel Brodin, Luigi De Petris, Sweden<br />
09:45 - 10:00 S01:6 Non-selective cyclooxygenase (COX) inhibition decreases shunt during one-lung<br />
ventilation <strong>for</strong> thoracic surgery.<br />
Danguole Rimeika, Sten GE Lindahl, Claes U Wiklund, Sweden<br />
08:30 - 10:15 S02 SCANSECT Symposium; Weaning from longterm assist devices Lecture room E5<br />
Moderators: Laila Hellgren-Johansson and Peter Svenarud<br />
Speakers:<br />
Lars Lund; Cardiological aspects<br />
Maria Eriksson; Evaluation of myocardial recovery by echocardiography<br />
Conny Rundby; The role of the perfusionist<br />
Asghar Khaghani; The Harefield experience<br />
08:30 - 10:00 S03 SATNU Oral abstract session Lecture room M2<br />
Theme: Dealing with patients' physical postoperative problems<br />
Moderators: Unni Kleppe Haukeland and Marita Ritmala-Castren<br />
08:30 - 08:45 S03:1 Postoperative nausea and vomiting after cardiac surgery: nursing point of view<br />
Timo Murkka, Anu Niemi, Kati Järvelä, Pasi Maaranen, Heini Huhtala, Tero Sisto, Finland<br />
08:45 - 09:00 S03:2 Prediction of the consumption of opioid analgesics following minimally invasive correction<br />
of pectus excavatum<br />
Kasper Grosen, Hans K. Pilegaard, Mogens P. Jensen, Denmark<br />
09:00 - 09:15 S03:3 Gabapentin <strong>for</strong> postoperative pain management after cardiac surgery with median sternotomy<br />
Vibeke Laursen, Mariann Tang, Imran Parvaiz, Vibeke Hjortdal, Denmark<br />
09:15 - 09:30 S03:4 The effect of soothing music in response to stress and relaxation during bed rest after open-<br />
heart surgery.<br />
Ulrica Nilsson, Sweden<br />
09:30 - 09:45 S03:5 Nursemanaged insulin protocol improves treatment of hyperglycaemia in patients with<br />
diabetes undergoing open heart surgery<br />
Aase Lange, Denmark<br />
09:45 - 10:00 S03:6 Prevalance of postoperative problems among Danish heart-operated patients 14 days after<br />
discharge from hospital<br />
Dorthe Ibsen, Helle Greve, Denmark<br />
10:00 - 10:30 S03:B SATNU Invited Lecture Lecture room M2<br />
Waiting <strong>for</strong> heart surgery<br />
Bodil Ivarsson introduced by Gunilla Barr<br />
12 www.sats<strong>2009</strong>.org
FRIDAY, 21 AUGUST <strong>2009</strong><br />
08:30 - 10:30 S04 Physiotherapists Lecture room M3<br />
08:30 - 09:00 Introduction<br />
Ulrika Thunström<br />
09:00 - 09:45 National guidelines <strong>for</strong> chest physiotherapy<br />
Charlotte Urell<br />
09:45 - 10:30 Current practice <strong>for</strong> chest physiotherapy<br />
Elisabeth Westerdahl<br />
Pause<br />
10:20 - 11:30 S05 <strong>SATS</strong> Cardiac Oral abstract session Lecture room M1<br />
Moderators: Odd Geiran and Åsa Haraldsson<br />
10:20 - 10:30 S05:1 Initial experience with a catheter based aortic valve implantation system.<br />
Henrik Ahn, Jacek Baranowski, Wolfgang Freter, Niels Erik Nielsen, Eva Nylander,<br />
Lars Wallby, Eva Tamas, Sweden<br />
10:30 - 10:40 S05:2 Echo-guided presentation of aortic valve minimises contrast medium exposure in Sapien<br />
aortic valve recipients.<br />
Jacek Baranowski, Henrik Ahn, Wolfgang Freter, Niels Erik Nielsen, Eva Nylander,<br />
Eva Tamas, Lars Wallby, Sweden<br />
10:40 - 10:50 S05:3 Survival and quality of life after aortic root replacement with cryopreserved homografts in<br />
acute endocarditis<br />
Sossio Perrotta, Obaid Aljassim, Odd Bech-Hanssen, Anders Jeppsson,<br />
Gunnar Svensson, Sweden<br />
10:50 - 11:00 S05:4 Mitral valve repair using Gore-tex neochordae, “respect rather than resect”.<br />
Susanne Juel Holme, John Christensen, Morten Kjøller, Thomas Fritz-Hansen, Denmark<br />
11:00 - 11:10 S05:5 Minimally invasive reoperative aortic valve surgery with patent coronary artery bypass grafts<br />
Giuseppe Raffa, Sudan, Carlo Pellegrini, Marcello Savasta, Matteo Pozzi, Mario Vigano, Italy<br />
11:10 - 11:20 S05:6 Hypothyroidism in cardiac surgery patients. A single unit follow-up.<br />
Aarne Jyrala, Gregory L Kay, United States<br />
11:20 - 11:30 S05:7 Continuous venovenous hemodialysis (CVVHD) with citrate calcium reduces<br />
postoperative bleeding complications after cardiac surgery<br />
Arndt-H. Kiessling, Michael Neher, Angela Kornberger, Andreas Lehmann, Bergner Raoul,<br />
Frank Isgro, Werner Saggau, Germany<br />
STOCKHOLM, SWEDEN 13<br />
www.exigus.se
FRIDAY, 21 AUGUST <strong>2009</strong><br />
10:45 - 13:00 S06 SCANSECT Oral abstract session Lecture room E5<br />
Moderators: Per Stensved and Else Nygreen<br />
10:45 - 11:00 S06:1 Fibrinogen and the acute inflammatory response after cardiac surgery<br />
Maria Kalabic, Anders Jeppsson, Helena Rexius, Sweden<br />
11:00 - 11:15 S06:2 Platelet aggregability be<strong>for</strong>e and after coronary artery bypass surgery<br />
Linda Önsten, Anders Jeppsson, Helena Rexius, Sweden<br />
11:15 - 11:30 S06:3 Will use of mini CPB lead to higher levels of haemoglobin, less use of blood products and<br />
improved fluid balance?<br />
Bente Övrebö, Hege Eikemo, Arve Mongstad, Finn Eliassen, Marit Farstad,<br />
Rune Haaverstad, Norway<br />
11:30 - 11:45 S06:4 In Vitro Comparison of the New In-line Monitor BMU 40 vs. the Conventional Laboratory<br />
Analyser ABL 700<br />
F. Oliver Grosse, Germany, David Holzhey, Volkmar Falk, Switzerland,<br />
Jan Schaarschmidt, Klaus Kraemer, Friedrich Wilhelm Mohr, Germany<br />
11:45 - 12:00 S06:5 Clinical Evaluation of the new BMU 40 In-Line Blood Analysis Monitor<br />
Jan Schaarschmidt, Michael Andrew Borger, Joerg Seeburger, Frank Oliver Grosse,<br />
Klaus Kraemer, Friedrich Wilhelm Mohr, Germany<br />
12:00 - 12:15 S06:6 ECMO - The Icelandic experience<br />
Thorsteinn Astradsson, Bjarni Torfason, Tomas Gudbjartsson, Liney Simonardottir,<br />
Felix Valsson, Iceland<br />
12:15 - 12:30 S06:7 Extracorporeal membrane oxygenation support <strong>for</strong> 59 days without changing the ecmo circuit<br />
Amrit Singh Thiara, Vivian Høyland, Hilde Norum, Tor Aasmundstad, Harald Karlsen,<br />
Arnt Fiane, Odd Geiran, Norway<br />
12:30 - 12:45 S06:8 Coagulation in oxygenator and arterial filter after recirculation<br />
Anne Louise Bellaiche, Peter Fast Nielsen, Pia Sprogøe, Oddvar Klungreseth, Denmark<br />
11:00 - 13:00 S07 SATNU Oral abstract session Lecture room M2<br />
Theme 11.00-11.45: Competence at work. Theme 11.45-13.00: Surviving heart disease<br />
Moderators: Anita Tracey and Lotte Brahe<br />
11:00 - 11:15 S07:1 How does nursing competence express itself in the operating room?<br />
Charlotte Walsoe, Denmark<br />
11:15 - 11:30 S07:2 The operating room nurses experiences of the medical equipment in their daily work<br />
Christine Roman-Emanuel, Doris Hägglund, Sweden<br />
11:30 - 11:45 S07:3 Surgical Team Member's Experiences, Routines and Views be<strong>for</strong>e Implementation of a<br />
Time-out protocol<br />
Shamini Murugesh, Arvid Haugen, Rune Haaverstad, Haldor Slettebø, Grethe Daavoy,<br />
Eirik Soefteland, Norway<br />
11:45 - 12:00 S07:4 Out of Hospital(OoH) management of patients on LVADs (Left ventricular assist devices).<br />
The Norwegian experience.<br />
Gro Sorensen, Einar Gude, Marianne Holter, Arnt Fiane, Norway<br />
12:00 - 12:15 S07:5 Gender and health-related quality of life after cardiac surgery<br />
Kari Hanne Gjeilo, Alexander Wahba, Pål Klepstad, Stian Lydersen, Roar Stenseth, Norway<br />
12:15 - 12:30 S07:6 Quality of life in patients and his relatives undergoing percutaneous pulmonary valve implant<br />
Brith Andresen, Gaute Døhlen, Lars Mathisen, Norway, Marit Andersen, Harald Lindberg,<br />
Erik Fosse, Norway<br />
12:30 - 12:45 S07:7 Addressing the Spouses Unique Needs after Cardiac Surgery when Recovery is<br />
Complicated by Heart Failure<br />
Susanna Ågren, Anna Strömberg, Rolf Svedjeholm, Sören Berg,<br />
Gunilla Hollman Frisman, Sweden<br />
12:45 - 13:00 S07:8 Patient education in a representative sample of patients having elective cardiac surgery in Iceland<br />
Heida Steinunn Olafsdottir, Brynja Ingadottir, Herdis Sveinsdottir, Iceland<br />
14 www.sats<strong>2009</strong>.org
FRIDAY, 21 AUGUST <strong>2009</strong><br />
11:00 - 11:30 S08 Physiotherapists Lecture room M3<br />
Smärta, lungfunktion och opiater<br />
Maria Antonsson introduced by Sofia Broman<br />
11:50 - 13:00 S09 <strong>SATS</strong> Cardiothoracic Oral abstract session Lecture room M1<br />
Moderators: Tómas Guðbjartsson and Kristiina Hersio<br />
11:50 - 12:00 S09:1 Outcome after pulmonary metastasectomy: Analysis of surgical resections during a 5 year period.<br />
Kåre Hornbech, Jesper B. Ravn, Daniel A. Steinbrüchel, Denmark<br />
12:00 - 12:10 S09:2 Surgical resection of pulmonary metastases from colorectal carcinoma in Iceland<br />
Halla Vidarsdottir, Pall Moller, Jon Gunnlaugur Jonasson, Tomas Gudbjartsson, Iceland<br />
12:10 - 12:20 S09:3 The No touch vein graft harvesting technique <strong>for</strong> CABG preserves a functional vasa vasorum<br />
Mats Dreifaldt, Domingos Souza, Sweden, Andrzej Loesch, John Muddle, United Kingdom,<br />
Mats Karlsson, Lars Norgren, Sweden, Michael Dashwood, United Kingdom<br />
12:20 - 12:30 S09:4 Is there a place <strong>for</strong> total endoscopic ablation of atrial fibrillation?<br />
Anders Ahlsson, Espen Fengsrud, Peter Linde, Hans Tyden, Anders Englund, Sweden<br />
12:30 - 12:40 S09:5 Sternal Closure with Thermoreactive clips in 1000 High risk patients<br />
- A Single Centre Cohort Study.<br />
Sendhil Kumaran Balasubramanian, Joel Dunning, Vassilios Avlonitis, Michael Gill,<br />
Andrew Goodwin, Andrew Owens, Simon Kendall, United Kingdom<br />
12:40 - 12:50 S09:6 Cardiac Surgery in Patients with Haemophilia<br />
Mariann Tang, Per Wierup, Kim Terp, Jørgen Ingerslev, Benny Sørensen, Denmark<br />
12:50 - 13:00 S09:7 Surgical correction of pectus excavatum and carinatum - six years of experiences at<br />
Karolinska University Hospital.<br />
Per Bergman, Sweden<br />
11:50 - 13:00 S10 <strong>SATS</strong> Basic Science Oral abstract session Lecture room E4<br />
Moderators: Gabriella Lindvall and Ulrik Sartipy<br />
11:50 - 12:00 S10:1 Injection of Mesenchymal Stem Cells Modified with VEGF Gene in Ischemic myocardium<br />
Improves Cardiac Function in Rats<br />
Ping Hua, China, Yanqi Yang, Sweden, Ju Chen, Jiangzhou Peng, Bosheng Chen,<br />
Jie Han, Youyu Wang, China<br />
12:00 - 12:10 S10:2 Effect of Down-Regulated Cyclophilin D on Protection of Endothelial Cells Against<br />
Oxidative Injury<br />
Jiangzhou Peng, China, Yanqi Yang, Sweden, Ping Hua, Ju Chen, Jie Han,<br />
Bosheng Chen, Lei Xue, China<br />
12:10 - 12:20 S10:3 Validation of cystatin C with iohexol clearance in cardiac surgery.<br />
Björn Brondén, Atli Eyjolfsson, Sten Blomquist, Henrik Jönsson, Sweden<br />
12:20 - 12:30 S10:4 Platelet reactivity during Cardiopulmonary bypass (CPB)<br />
- Changes related to postoperative bleeding<br />
Gustaf Ehnsiö, Joakim Norderfeldt, Sören Berg, Joakim Alfredsson, Sweden<br />
12:30 - 12:40 S10:5 The Human heart releases cardiotrophin-1after coronary artery bypass grafting with<br />
cardiopulmonary bypass<br />
Yikui Tian, Xinhua Ruan, China, Jari Laurikka, Seppo Laine, Matti Tarkka, Finland,<br />
Minxin Wei, China<br />
12:40 - 12:50 S10:6 Acute kidney injury following coronary artery bypass surgery using the RIFLE criteria<br />
Solveig Helgadottir, Olafur Indridason, Gisli Sigurdsson, Hannes Sigurjonsson,<br />
Thorarinn Arnorsson, Tomas Gudbjartsson, Iceland<br />
13:00 - 14:15 Lunch; visit the exhibition!<br />
STOCKHOLM, SWEDEN 15
FRIDAY, 21 AUGUST <strong>2009</strong><br />
14:15 - 15:45 S11 Symposium; Humanitarian Work in Cardiac Surgery Lecture room M2<br />
Moderators: Dan Lindblom and Eva Ahlgren<br />
Speakers:<br />
Stefan Peterson; Impact of Cardiovascular Diseases in Developing Countries<br />
Sylvain Chauvaud; Experiences by Chaine de l´espoir<br />
Gino Strada; Experiences by Emergency<br />
15:45 - 16:15 Coffee; visit the exhibition!<br />
16:15 - 17:15 S12 <strong>SATS</strong> Invited Lecture Lecture room M1<br />
Critically interpreting the mitral literature<br />
Anelechi Anyanwu introduced by Sten Samuelsson<br />
16:15 - 17:15 S13 SCANSECT Invited Lecture Lecture room E5<br />
Long Term Assist Devices previous, current and <strong>for</strong>ecast<br />
Heinz-Hermann Weitkemper introduced by Anne-Louise Bellaiche<br />
16:15 - 17:15 S14 SATNU Invited Lecture Lecture room M2<br />
Phychosocial aspects of heart failure<br />
Anna Strömberg introduced by Anita Tracey<br />
16:15 - 17:15 S15 Physiotherapists: Exchange of experiences Lecture room M3<br />
Moderators: Ulrika Thunström and Sofia Broman<br />
17:30 - 18:45 Awards and pre-dinner party<br />
18:45 Buses leave from Kistamässan<br />
19:30 Buffet dinner at the Stockholm City Hall<br />
21:15 Steamboat tour in the Stockholm Archipelago<br />
16 www.sats<strong>2009</strong>.org<br />
Stockholm Visitors Board - Christer Lundin
SATURDAY, 22 AUGUST <strong>2009</strong><br />
08:30 - 10:00 S16 <strong>SATS</strong> and SCANSECT; Cardiogenic shock in myocardial Infarction Lecture room M1<br />
Moderators: Anders Albåge and Jan Hultman<br />
Speakers:<br />
Lars Lund; Background and Current Guidelines <strong>for</strong> Intervention<br />
Lars Wiklund; Revascularization and Other Surgical Options<br />
Asghar Khaghani; Mechanical support<br />
08:30 - 09:30 S17 SATNU Invited Lecture Lecture room M2<br />
Reducing VAP in the ICU<br />
Eva Joelsson Alm introduced by Gunilla Barr<br />
08:30 - 10:00 S18 Physiotherapists Oral abstract session Lecture room M3<br />
Moderator: Gun Faager<br />
08:40 - 09:00 S18:1 Precautions after midline sternotomy. Are they necessary?<br />
Barbara Cristina Brocki, Charlotte Brun Thorup, Hanne Skindbjerg, Marianne Svalgaard,<br />
Jan Jesper Andreasen, Denmark<br />
09:00 - 09:20 S18:2 A randomized controlled trial on deep breathing exercises with positive expiratory<br />
pressure after cardiac surgery<br />
Charlotte Urell, Margareta Emtner, Marie Breidenskog, Elisabeth Westerdahl, Sweden<br />
09:20 - 09:40 S18:3 Physical activity on prescription (FaR®)-a long term follow-up of FaR® prescribed<br />
at a university hospital<br />
Susanna Wennman, Agneta Ståhle, Sweden<br />
09:30 - 10:30 SATNU General Assembly Lecture room M2<br />
10:00 - 10:30 <strong>SATS</strong> General Assembly Lecture room M1<br />
10:00 - 10:30 SCANSECT General Assembly Lecture room E5<br />
10:30 - 11:00 Pause; visit the exhibition!<br />
11:00 - 13:00 S19 Main topic 2; Transcatheter Valve Techniques Lecture room M2<br />
Moderator: Anders Jönsson<br />
History and Future of Aortic Valve Implantation<br />
Speaker: Ottavio Alfieri<br />
Invited discussant: Kenneth Pehrsson<br />
History and Future of Mitral Valve Interventions<br />
Speaker: Francesco Maisano<br />
Invited discussant: Reidar Winter<br />
13:00 - 13:15 Closing remarks Lecture room M2<br />
Jan Hultman<br />
STOCKHOLM, SWEDEN 17
Invited Speakers<br />
Ottavio Alfieri Ospedale San Raffaele, Milan, Italy<br />
Lars Algotsson Lund University Hospital, Lund, Sweden<br />
Maria Antonsson Uppsala University Hospital, Uppsala, Sweden<br />
Anelechi Anyanwu Mount Sinai Hospital, New York, USA<br />
Gerald Buckberg David Geffen School of Medicine, UCLA, Los Angeles, USA<br />
Sylvain Chauvaud La Chaîne de l’Espoir, Paris, France<br />
Maria Eriksson Karolinska University Hospital, Stockholm, Sweden<br />
Bodil Ivarsson Lund University Hospital, Lund, Sweden<br />
Eva Joelsson-Alm South Hospital, Stockholm, Sweden<br />
Asghar Khaghani Royal Brompton and Harefield Hospitals, London, UK<br />
Lars Lund Karolinska University Hospital, Stockholm, Sweden<br />
Francesco Maisano Istituto Scientifico San Raffaele, Milan, Italy<br />
Kenneth Pehrsson Karolinska University Hospital, Stockholm, Sweden<br />
Stefan Peterson Karolinska Institutet, Stockholm, Sweden<br />
Gino Strada Emergency, Milan, Italy<br />
Anna Strömberg Linköping University, Linköping, Sweden<br />
Charlotte Urell Uppsala University, Uppsala, Sweden<br />
Heinz-Hermann Weitkemper Bad Oeynhausen, Germany<br />
Elisabeth Westerdahl Örebro University Hospital, Örebro, Sweden<br />
Lars Wiklund Sahlgrenska University Hospital, Gothenburg, Sweden<br />
Reidar Winter Karolinska University Hospital, Stockholm, Sweden<br />
- Professor Gerald Buckberg, UCLA, Los Angeles, will give the annual Clarence Crafoord lecture, which usually<br />
is arranged during the Swedish annual meeting. Professor Buckberg was the 2007 Recipient of the American<br />
<strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery Scientific Achievement Award. He has published a large number of important<br />
articles in the fields of myocardial protection and left ventricular reconstruction.<br />
- Professor Anelechi Anyanwu, Director of Heart and Heart-Lung Transplantation at the Mount Sinai Medical<br />
Center, New York, will give a lecture on "How to read the mitral literature". His presentation might be considered as<br />
a follow-up to the very successful <strong>SATS</strong> postgraduate course in Copenhagen 2008, "From methodology to clinical<br />
evidence based decision making"<br />
Registration<br />
Registration & In<strong>for</strong>mation Desk<br />
Opening hours:<br />
Thursday, 20 August 10:00 - 17:30<br />
Friday, 21 August 07:30 - 17:30<br />
Saturday, 22 August 07:30 - 13:00<br />
Registration Fee (including VAT).<br />
On-site registration fee:<br />
• Delegates (members): SEK 5 100<br />
• Delegates (non-members): SEK 5 300<br />
• Nurses Physiotherapists and other health professionals fees: SEK 4 300<br />
• Nurses’ and Physiotherapists - only participation in nurses or<br />
physiotherapists sessions on Friday and Saturday: SEK 1 800<br />
• Accompanying persons: SEK 1 500<br />
On-site registration - please note some of the events might be fully booked.<br />
Cancellation & refund policy<br />
Credit cannot be given <strong>for</strong> unattended event, late arrivals or early departures.<br />
Hotel Accommodation<br />
The registration desk will handle inquires related to hotel accommodation.<br />
18 www.sats<strong>2009</strong>.org
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Cardioblate® Irrigated RF Surgical Ablation System<br />
UC<strong>2009</strong>05135 EE
Social <strong>Program</strong>me<br />
All events are available <strong>for</strong> participants and accompanying persons and should have been prebooked on the<br />
registration <strong>for</strong>m. For late bookings – please contact the registration desk <strong>for</strong> availability.<br />
A ticket is mandatory <strong>for</strong> entrance and will be handed out at the registration desk.<br />
Gala Dinner at Solliden, Skansen<br />
Thursday, 20 August at 19.30.<br />
The Gala Dinner will be held at Solliden Restaurant at Skansen, with a fabulous view of the Stockholm waterfront.<br />
The restaurant is located at Skansen, which is the world’s oldest open-air museum, founded in 1891.<br />
The Solliden Restaurant was built 1950-1952 and several well-known artists were commissioned to decorate the<br />
new restaurant, among them Hilding Linnqvist who painted the large fresco on the staircase called “The Story of<br />
Sweden”. This is a festive opportunity <strong>for</strong> all participants to meet and socialize.<br />
SEK 500 <strong>for</strong> registered delegates<br />
SEK 700 <strong>for</strong> non-registered delegates<br />
Dress code: Business suit/suit and tie.<br />
Individual transport.<br />
Reception at the Stockholm City Hall<br />
Friday, 21 August at 19.30.<br />
The City of Stockholm invites you to a buffet dinner at the Stockholm City Hall. The City Hall was designed by<br />
architect Ragnar Östberg in 1923 and is beautifully situated on the Riddarfjärden waterfront in central Stockholm.<br />
It is home to the central administration of the city. However, the City Hall is mostly famous <strong>for</strong> the Nobel Prize<br />
festivities, which are held in the Blue Hall every year on 10 December.<br />
By invitation from the City of Stockholm. Pre-registration is necessary.<br />
Transportation from the conference venue will be arranged.<br />
Steam boat tour in Stockholm Archipelago<br />
Friday, 21 August at 21.15.<br />
Experience the beautiful inner archipelago of Stockholm onboard a traditional steam boat. Enjoy a cup of coffee<br />
while viewing the typical archipelago sights and Stockholm’s magnificent location between Lake Mälaren and the<br />
sea. Extra drinks can be purchased in the bar onboard.<br />
SEK 100 <strong>for</strong> registered delegates<br />
SEK 200 <strong>for</strong> non-registered delegates<br />
20 www.sats<strong>2009</strong>.org
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General In<strong>for</strong>mation<br />
in alphabetic order<br />
Audio-visual facilities<br />
All lecture halls are equipped with PC and PowerPoint.<br />
Business hours & Shopping<br />
Shops are open between 10.00 and 18.00 hrs on weekdays and from 10.00 to 15.00 hrs on Saturdays. Shops in the<br />
City centre have extended opening hours, some even on Sundays between 12.00 and 16.00 hrs. The main shopping<br />
streets in the centre of Stockholm are: Hamngatan, Biblioteksgatan, Drottninggatan and Västerlånggatan in the Old<br />
Town. The Kista Galleria (shopping mall) with its´ 125 shops is only a few minutes walk from the conference venue.<br />
Open 7 days a week between 10.00-21.00.<br />
Certificate of Attendance<br />
A Certificate of Attendance is inserted in the conference bag.<br />
Check – in/-out<br />
Hotel check-in time is 15.00 hrs or later. Check-out time is 12.00.<br />
Climate and Clothing<br />
The average temperature in August is around 18-20°C (approx. 65-68°F).<br />
Conference Language<br />
The official language of the conference is English. There will be no simultaneous interpreting.<br />
Conference Venue<br />
Kistamässan. Kista Expo Center. For in<strong>for</strong>mation on the venue, please visit the venue website:<br />
www.kistamassan.com. Address: Kistamässan, Kistagången 1, 164 22 KISTA. Phone: +46 8-50665000<br />
Currency & Credit Cards<br />
The currency in Sweden is the Swedish Krona, SEK. A currency calculation can be found online at:<br />
www.x-rates.com/calculator.html<br />
Commonly accepted credit cards in hotels, restaurants and shops are American Express, Diners Club, Visa, Master<br />
Card and Euro card. Restaurants and shops generally display signs indicating what cards they accept. The registration<br />
desk accepts all these cards.<br />
Evaluation of the conference<br />
Shortly after the conference, an evaluation <strong>for</strong>m will be e-mailed to you. We would appreciate if you could fill in the<br />
<strong>for</strong>m as it is important <strong>for</strong> us to know what you think of this meeting and what we can improve to the next meeting.<br />
Exhibition<br />
The commercial exhibition will be held in conjunction with the conference, adjacent to the session halls.<br />
Insurance<br />
Neither the Conference Organisers nor the Conference Secretariat accept any liability <strong>for</strong> personal injuries sustained,<br />
or <strong>for</strong> loss or damage to property belonging to conference participants, either during or as a result of the conference.<br />
It is strongly recommended that you purchase an insurance policy of your choice as you register <strong>for</strong> the conference<br />
and book your travel. The insurance should be purchased in advance.<br />
Name Badges<br />
The delegate’s name badge will be provided at the registration desk. All delegates are required to wear the badge<br />
throughout the conference. Only badge holders will be admitted to the sessions.<br />
On-site registration<br />
On-site registrations will be accepted, however availability of hotel accommodation and participation in the social<br />
tours/events at that time may be severely limited.<br />
22 www.sats<strong>2009</strong>.org
Smoking policy<br />
Kistamässan and the evening venues are all non smoking. Smoking is banned in public places in Stockholm, on<br />
public transport, in stores, restaurants and most pubs. Hotels offer special rooms <strong>for</strong> smokers. Please indicate your<br />
request on the registration <strong>for</strong>m, when you make your hotel reservation.<br />
Speakers Ready room<br />
Presenters are kindly requested to hand in their presentation to the technicians in the Speaker´s Ready room, E3,<br />
at least 2 hours prior your session starts. If you bring your own laptop, please be sure to visit the technicians be<strong>for</strong>e<br />
your lecture in order to ensure the right equipment is in place.<br />
Speakers´Ready room, E 3 – opening hours<br />
Thursday, 20 August: 10:00 – 18:00<br />
Friday, 21 August: 07:30 – 17:00<br />
Saturday, 22 August: 07:30 – 13:00<br />
The lecture halls will be equipped with PC with PowerPoint.<br />
Time zone<br />
Sweden is 1 hour ahead of Greenwich Mean Time (GMT).<br />
Tourist in<strong>for</strong>mation<br />
For tourist in<strong>for</strong>mation about Stockholm and Sweden, please visit the website: www.stockholmtown.com, or contact<br />
the Tourist Centre on phone: +46 8 508 28 508 or info@svb.stockholm.se.<br />
Transportation<br />
Stockholm has a well-developed local transport system. For more in<strong>for</strong>mation please visit SL (Stockholm’s public<br />
transport website), www.sl.se.<br />
Airports and Transport<br />
Arlanda Airport is located 42 km north of Stockholm.<br />
The Arlanda Express is the train service that links Stockholm City with the Airport. Book your Arlanda Express<br />
ticket in advance at the same time you register to the conference. MCI offers discounted tickets <strong>for</strong> travel with the<br />
Arlanda Express train from Arlanda to Stockholm. Your confirmation letter will serve as a ticket when presented to<br />
the train conductor. SEK 220 each way.<br />
Other ways to reach the city:<br />
Taxi: We recommend that you request a fixed price from the airport to the city, approx. SEK 450 - 550. Arlanda<br />
Airport-Kistamässan approx. SEK 385.<br />
Bus: There is direct bus connection from Arlanda Airport to the City Terminal in Stockholm. From Saturday, August<br />
22 there is also a direct connetion Kistamässan-Arlanda Airport. The journey from the airport to central station,<br />
takes about 40 minutes. The bus leaves Arlanda airport every 10 minutes. For in<strong>for</strong>mation on the airport buses<br />
(prices, time tables etc.) please visit www.flygbussarna.se<br />
Bromma Airport<br />
Bromma is Stockholm's city airport and your fastest alternative to and from the Swedish capital. Bus: There is direct<br />
bus connection from Bromma Airport to the City Terminal in Stockholm. From Saturday, August 22 there is also a<br />
direct connection Kistamässan – Bromma airport, adapted to flight arrivals and departures. Driving time from central<br />
Stockholm is approx 20 minutes. From Bromma airport to Kistamässan approx 15 minutes. Local transport (SL):<br />
You can also catch a local bus to/from Stockholm-Bromma airport. Please visit www.sl.se <strong>for</strong> more in<strong>for</strong>mation.<br />
Taxi: We recommend that you request a fixed price from the airport to the city, approx.SEK 220. Bromma Airport-<br />
Kistamässan approx. SEK 210.<br />
For in<strong>for</strong>mation on the airport buses (prices, time tables etc.) please visit www.flygbussarna.se<br />
Travel to/from Stockholm central station to/from Kistamässan:<br />
By underground: Catch the Blue line from Rådhuset, direction 'Akalla' or the Green line direction 'Hässelby' and<br />
change trains at Fridhemsplan to Blue line 'Akalla'. The stations Kungsträdgården and T-Centralen are closed during<br />
the summer. Get off at the stop 'Kista' (15-20 min), a 10 minute walk to Kistamässan.<br />
By commuter train: Catch the commuter train from Stockholm central with the direction 'Märsta'. You get off at the<br />
stop 'Helenelunds station' (12 min travel) a 5 minute walk to Kistamässan.<br />
STOCKHOLM, SWEDEN 23
Visiting Stockholm<br />
Welcome to Stockholm, the Royal Capital of Sweden. Discover a city like no other - a city built on<br />
14 islands, where you are never far from the water. Well-preserved medieval buildings stand alongside<br />
modern architecture. Stockholm is also home of the Nobel Prize. And just outside the city, the archipelago<br />
of 24 000 islands is waiting to be explored.<br />
Stockholm is a city of contrasts - water and islands, history and innovation, small town and big city, short winter days<br />
and long, light summer nights - with a dazzling array of impressions. Thanks to the city’s compact size, you can see<br />
and do most things in a short space of time - which makes it a perfect destination <strong>for</strong> city breaks or longer stays, all<br />
the year round.<br />
Discover a city of contrasts. Go back 750 years in time and feel the medieval atmosphere of the Old Town<br />
“Gamla Stan” as you wander through the narrow streets. Stockholm has got history - but also the latest in<br />
fashion and IT. The trendy Stockholmers are often used as a test market by international companies, as they<br />
are quick to pick up on the latest trends. This is most obvious on the island of Södermalm, a hotbed of fashion,<br />
young culture and entertainment.<br />
Stockholm is one third water, one third green belt and one third city. The island of Djurgården, the world´s first<br />
National City Park, is only a short walk from the pulse of the inner city. Stockholmers and visitors alike come here<br />
to relax in the leafy shade and rest their eyes on green.<br />
Stockholm’s excellent transport links mean the city can offer reasonable access <strong>for</strong> all participants.<br />
Stockholm is very well positioned with most of Europe within three hours reach. It is a genuine meeting point in every<br />
respect and an increasingly important hub <strong>for</strong> flights to major destinations in the Baltic Sea Region, European Union<br />
and the expansive global community.<br />
Useful links<br />
Stockholm Visitor’s Guide<br />
This is the site where you can find nearly everything you need to know as a tourist in Stockholm:<br />
www.stockholmtown.com<br />
Guided boat tours<br />
During the period of April-December we highly recommend a 1 to 2 hour guided boat tour under the bridges of<br />
Stockholm:<br />
www.stockholmsightseeing.com<br />
Bus tours<br />
Guided bus tours around Stockholm, offered in eleven different languages, are available throughout the year:<br />
www.citysightseeing.com<br />
Boat tours in the archipelago and Lake Mälaren<br />
If you so only have one night or one day off in Stockholm, you cannot miss our archipelago. It consists of 24,000<br />
islands, of which only 3,000 are inhabited. Take a short trip of only a few hours, preferably during the evening with<br />
dinner onboard, to this unique place in the world.<br />
Choose Strömma Kanalbolaget if you prefer travelling by a steamboat or a boat from the turn of the century:<br />
www.strommakanalbolaget.com<br />
Choose Cinderellabåtarna if you want to see the whole archipelago, at 30 knots per hour, in only a few hours:<br />
www.cinderellabatarna.com<br />
Shopping in the city<br />
Here are some good links to great shopping in Stockholm city centre. NK is an exclusive department store: www.nk.se<br />
Sturegallerian is a stylish mall in the middle of the hottest district in town: www.sturegallerian.se<br />
Gallerian is one of the first malls in Sweden: www.gallerian.se<br />
24 www.sats<strong>2009</strong>.org
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Kistamässan Overview<br />
KONFERENS<br />
Ground Floor<br />
KONFERENSENTRÉ<br />
Torshamnsgatan 18 c<br />
E10<br />
VIP-Lounge<br />
E9<br />
www.kistamassan.com<br />
E7<br />
E5<br />
26 www.sats<strong>2009</strong>.org<br />
E8<br />
E6<br />
WC WC<br />
Presscenter<br />
KONFERENSLOBBY<br />
E6<br />
GARDEROB<br />
RECEPTION<br />
E1<br />
E2<br />
E4<br />
HWC<br />
E3<br />
WC<br />
WC<br />
MÄSSHALL | ENTRÉHALL<br />
E3<br />
Speakers<br />
ready room<br />
E4
Kistamässan Overview<br />
KONFERENS<br />
First Floor<br />
M1 M2<br />
M1 M2<br />
Exhibition<br />
HALL & 1<br />
Poster area<br />
HALL 2<br />
www.kistamassan.com<br />
Mässplan Entresolplan<br />
M3<br />
M4 M3<br />
STOCKHOLM, SWEDEN 27<br />
M5
Exhibition<br />
Exhibition opening hours<br />
Thursday 20 August: 12:00 - 17:30<br />
Friday 21 August: 08:00 - 18:45<br />
Saturday 22 August: 08:00 - 13:30<br />
List of Exhibitors<br />
Company Stand No.<br />
Aesculap AG B:20<br />
ATS Medical E:14<br />
Baxter Medical AB B:30<br />
Covidien Sverige AB C:20<br />
Carmel Pharma AB C:21<br />
Dicamed AB B:27<br />
Dräger Medical Sverige AB B:10<br />
Edwards Lifesciences E:21<br />
Hemax Medical A/S B:15<br />
Johnson & Johnson Nordic C:25<br />
Kanmed AB B:15<br />
KLS Martin Group B:12<br />
KRAUTH Surgical GmbH C:11<br />
Maquet Nordic AB D:31<br />
Master Surgery Systems AS B:21<br />
Medela Medical AB B:13<br />
Mediplast AB C:23<br />
Medi-Stim ASA E:31<br />
Medtronic AB E:11<br />
Orion Pharma AB C:13<br />
Philips Healthcare B:09<br />
Qualiteam s.r.l. B:24<br />
<strong>Scandinavian</strong> Cardiovascular Journal B:22<br />
Sorin Group Scandinavia AB C:10<br />
St. Jude Medical Sweden AB E:25<br />
SWEDISH ORPHAN INTERNATIONAL AB B:07<br />
Synthes AB B:11<br />
TERUMO D:30<br />
Vingmed Svenska AB C:30<br />
28 www.sats<strong>2009</strong>.org
M2<br />
M1<br />
Exhibition Floor Plan<br />
STOCKHOLM, SWEDEN 29
Sponsors<br />
The organisers acknowledge the following organisations <strong>for</strong> their generous contribution:<br />
Gold Sponsor<br />
Silver Sponsors<br />
Bronze Sponsors<br />
30 www.sats<strong>2009</strong>.org
Authors' Index<br />
A<br />
Aasmundstad, Tor S06:7<br />
Aazami, Mathias P01:41, P01:26<br />
Abdel Aal, Mohamed P01:19, P01:20<br />
Agger, Peter P01:03, P01:04<br />
Ahlsson, Anders S09:4<br />
Ahn, Henrik S05:1, P01:43, S05:2<br />
Aittomäki, Kristiina P01:32<br />
Alfredsson, Hordur P01:16<br />
Alfredsson, Joakim S10:4<br />
Alho, Hanni P01:32<br />
Aljassim, Obaid S05:3<br />
Andersen, Henning Rud S01:4<br />
Andersen, Karl P01:06<br />
Andersen, Knut S. P01:36<br />
Andersen, Lars W. S01:3<br />
Andersen, Marit S07:6<br />
Anderson, Rober H. P01:04<br />
Andreasen, Jan Jesper S18:1<br />
Andreassen, Arne K. P01:29, P01:30<br />
Andresen, Brith S07:6<br />
Arnorsson, Thorarinn<br />
P01:23, S10:6, P01:12<br />
Asgeirsson, Hilmir P01:15<br />
Astradsson, Thorsteinn S06:6<br />
Avlonitis, Vassilios S09:5<br />
B<br />
Balasubramanian, Sendhil Kumaran<br />
S09:5<br />
Baranowski, Jacek<br />
S05:1, P01:43, S05:2<br />
Bech-Hanssen, Odd S05:3<br />
Beck, Hans J. P01:14<br />
Bellaiche, Anne Louise S06:8<br />
Benetis , Rimantas P01:42<br />
Berg, Sören S07:7, S10:4<br />
Bergman, Per S09:7, P01:13, S01:5<br />
Bjessmo, Staffan S01:2<br />
Bjornholt, Jorgen P01:30<br />
Björnsson, Jóhannes P01:17<br />
Blomquist, Sten S10:3<br />
Bondo Jørgensen, Louise P01:05<br />
Borger, Michael Andrew S06:5<br />
Breidenskog, Marie S18:2<br />
Brocki, Barbara Cristina S18:1<br />
Brodin, Daniel P01:13, S01:5<br />
Brondén, Björn S10:3<br />
Brorsson, Bengt P01:25<br />
Böing, Ingeborg S01:4<br />
C<br />
Chen, Bosheng S10:1, S10:2<br />
Chen, Ju S10:2, S10:1<br />
Christensen, John S05:4<br />
D<br />
Daavoy, Grethe S07:3<br />
Dainius, Karciauskas P01:42<br />
Dashwood, Michael S09:3<br />
De Petris, Luigi S01:5<br />
Dreifaldt, Mats S09:3<br />
Drevdal, Julie P01:45<br />
Dunning, Joel S09:5<br />
Døhlen, Gaute S07:6<br />
E<br />
Eggen Hermansen, Stig P01:28<br />
Egle, Ereminiene P01:42<br />
Ehnsiö, Gustaf S10:4<br />
Eikemo, Hege S06:3<br />
Eliassen, Finn S06:3<br />
Ellensen, Vegard Skalstad P01:36<br />
Emtner, Margareta S18:2<br />
Englund, Anders S09:4<br />
Eriksson, Heidi P01:31<br />
Eyjolfsson, Atli S10:3<br />
F<br />
Falk, Volkmar S06:4<br />
Farstad, Marit S06:3<br />
Fengsrud, Espen S09:4<br />
Fiane, Arnt E.<br />
S06:7, S07:4, P01:29, P01:30<br />
Fluger, Ivo P01:07<br />
Fosse, Erik S07:6<br />
Frandsen, Jesper P01:04<br />
Franzén, Stefan P01:37<br />
Freter, Wolfgang<br />
S05:2, S05:1, P01:43<br />
Frey, Joana P01:08<br />
Fritz-Hansen, Thomas S05:4<br />
STOCKHOLM, SWEDEN 31<br />
G<br />
Gardarsdottir, Marianna P01:06<br />
Geiran, Odd R. S06:7, P01:29, P01:30<br />
Gill, Michael S09:5<br />
Gjeilo, Kari Hanne S07:5<br />
Gluud, Christian S01:3<br />
Goodwin, Andrew S09:5<br />
Gottfredsson, Magnus P01:11<br />
Greve, Helle S03:6<br />
Grosen, Kasper S03:2<br />
Grosse, F. Oliver S06:5<br />
Grosse, Frank Oliver S06:4<br />
Grulichova, Jana P01:07<br />
Gudbjartsson, Tomas<br />
P01:06, P01:11, P01:12, P01:14,<br />
P01:15, P01:16, P01:17, P01:18,<br />
P01:23, S06:6, S09:2, S10:6<br />
Gude, Einar P01:29, P01:30, S07:4<br />
Gudjonsdottir, Marta P01:14, P01:15<br />
Gudmundsdottir, Ingibjorg P01:11<br />
Gudmundsson, Gunnar P01:17<br />
Gunnarsson, Gunnar Thor P01:06<br />
Gunnarsson, Sverrir I. P01:14, P01:15<br />
H<br />
Haaverstad, Rune<br />
P01:36, P01:45, S06:3, S07:3<br />
Hajek, Roman P01:07<br />
Han, Jie S10:1, S10:2<br />
Harjula, Ari P01:31<br />
Hasenkam, J Michael P01:03, S01:1<br />
Haugen, Arvid S07:3<br />
Haukeland, Unni Kleppe P01:45<br />
Helgadottir, Solveig S10:6<br />
Hiippala, Seppo<br />
Hjortdal, Vibeke E.<br />
P01:22<br />
P01:03, P01:04, S01:4, S03:3<br />
Hollman Frisman, Gunilla S07:7<br />
Holm, Jonas P01:40<br />
Holm, Peter P01:44<br />
Holme, Susanne Juel S05:4<br />
Holter, Marianne S07:4<br />
Holzhey, David S06:4<br />
Hornbech, Kåre S09:1<br />
Hreinsson, Hreinsson P01:12<br />
Hua, Ping S10:1, S10:2<br />
Huhtala, Heini S03:1<br />
Håkanson, Erik P01:40<br />
Hägglund, Doris S07:2<br />
Hämmäinen, Pekka P01:31<br />
Høyland, Vivian S06:7
I<br />
Ibsen, Dorthe S03:6<br />
Indridason, Olafur S10:6<br />
Ingadottir, Brynja S07:8<br />
Ingerslev, Jørgen S09:6<br />
Isaksson, Helgi P01:16<br />
Isgro, Frank S05:7<br />
Ivert, Torbjörn P01:25<br />
J<br />
Jakobsen, Carl-Johan S01:4<br />
Javangula, Kalyana<br />
P01:21, P01:33, P01:34, P01:35<br />
Jensen, Henrik S01:1<br />
Jensen, Mogens P. S03:2<br />
Jensen, Morten S01:1<br />
Jeppsson, Anders<br />
P01:01, P01:02, S05:3, S06:1, S06:2<br />
Joergensen, Inge Selchau P01:48<br />
Johannsson, Kristinn B.<br />
P01:14, P01:15<br />
Jonasson, Jon Gunnlaugur S09:2<br />
Jonsson, Steinn P01:16<br />
Jurga, Juliane P01:27<br />
Jyrala, Aarne S05:6<br />
Järvelä, Kati S03:1<br />
Jönsson, Anders P01:44<br />
Jönsson, Henrik S10:3<br />
K<br />
Kaartinen, Maija P01:39<br />
Kalabic, Maria S06:1<br />
Karciauskas, Dainius P01:42<br />
Kargar, Faranak P01:26, P01:41<br />
Karlsen, Harald S06:7<br />
Karlsson, Mats S09:3<br />
Kay, Gregory L S05:6<br />
Kendall, Simon S09:5<br />
Kiessling, Arndt-H. S05:7<br />
Kjøller, Morten S05:4<br />
Klaaborg, Kaj-Erik S01:4<br />
Klemenzson, Gudmundur P01:06<br />
Klepstad, Pål S07:5<br />
Klungreseth, Oddvar S06:8<br />
Kolackova, Martina P01:51<br />
Kornberger, Angela S05:7<br />
Kraemer, Klaus S06:4, S06:5<br />
Krejsek, Jan P01:51<br />
Kubicek, Jaroslav P01:51<br />
Kudlova, Manuela P01:51<br />
L<br />
Laine, Seppo S10:5<br />
Lange, Aase S03:5<br />
Langova, Katerina P01:07<br />
Laurikka, Jari S10:5<br />
Laursen, Vibeke S03:3<br />
Lehmann, Andreas S05:7<br />
Lemström, Karl P01:31<br />
Lindahl, Sten GE S01:6<br />
Lindberg, Harald S07:6<br />
Linde, Peter S09:4<br />
Lindvall, Bo S01:2<br />
Lindvall, Gabriella S01:2<br />
Loesch, Andrzej S09:3<br />
Lonský, Vladimir<br />
P01:07, P01:09, P01:51<br />
Lund, Jens S01:3<br />
Lunkenheimer, Paul P. P01:04<br />
Lydersen, Stian S07:5<br />
Lygren, Heidi P01:45<br />
M<br />
Maaranen, Pasi S03:1<br />
Maasilta, Paula P01:32, P01:39<br />
Madsen, Jan K. S01:3<br />
Magnusson, Björn P01:14, P01:15<br />
Malek, Hadi P01:26<br />
Mandak, Jiri P01:51<br />
Manilla, Maria N. P01:27<br />
Mariusdottir, Elin P01:18<br />
Mathisen, Lars S07:6<br />
Mohebi, Ahmad P01:41<br />
Mohr, Friedrich Wilhelm S06:4, S06:5<br />
Molitor, Martin P01:07, P01:09<br />
Moller, Pall S09:2<br />
Mongstad, Arve S06:3<br />
Muddle, John S09:3<br />
Murkka, Timo S03:1<br />
Murugesh, Shamini S07:3<br />
Mushtaq, Abid P01:34<br />
Musilová, Petra P01:32<br />
Myrmel, Truls P01:28<br />
Mäki, Kaisa P01:10<br />
Møller, Christian H S01:3<br />
Møller-Madsen, Maria Kirstine P01:03<br />
32 www.sats<strong>2009</strong>.org<br />
N<br />
Nair, Unnikrishnan<br />
P01:21, P01:33, P01:34, P01:35<br />
Neher, Michael S05:7<br />
Nielsen, Eva P01:04<br />
Nielsen, Hans Henrik Møller S01:4<br />
Nielsen, Niels Erik<br />
P01:43, S05:1, S05:2<br />
Nielsen, Peter Fast S06:8<br />
Nielsen, Sten Lyager S01:1<br />
Niemi, Anu S03:1<br />
Nilsson, Ulrica S03:4<br />
Njåstad, Anita P01:45<br />
Noohi, Freidoun P01:41<br />
Norderfeldt, Joakim S10:4<br />
Norgren, Lars S09:3<br />
Norum, Hilde S06:7<br />
Nylander, Eva<br />
P01:37, P01:43, S05:1, S05:2<br />
Nyman, Jesper P01:27<br />
O<br />
Oddsson, Saemundur J. P01:23<br />
Olafsdottir, Heida Steinunn S07:8<br />
Olafsdottir, Thora Sif P01:17<br />
Oterhals, Kjersti P01:45<br />
Owens, Andrew S09:5<br />
P<br />
Papaspyros, Sotoris<br />
P01:21, P01:33, P01:34<br />
Parvaiz, Imran S03:3<br />
Pellegrini, Carlo S05:5<br />
Peng, Jiangzhou S10:1, S10:2<br />
Perko, Mario S01:3<br />
Perrotta, Sossio S05:3<br />
Persson, Jenny P01:49<br />
Petursdottir, Vigdis P01:06<br />
Piilonen, Anneli P01:31<br />
Pilegaard, Hans K. S03:2<br />
Pooraliakbar, Hamid-Reza P01:26<br />
Povilas, Jakuska P01:42<br />
Pozzi, Matteo S05:5<br />
Påhlman, Carin P01:37<br />
Päiväniemi, Outi P01:32
R<br />
Raffa, Giuseppe S05:5<br />
Raoul, Bergner S05:7<br />
Rasmussen, Tina Seidelin P01:50<br />
Ravn, Jesper B. S09:1<br />
Rexius, Helena P01:01, S06:1, S06:2<br />
Rimeika, Danguole S01:6<br />
Ringgaard, Steffen P01:03, S01:1<br />
Roman-Emanuel, Christine<br />
P01:01, P01:02, S07:2<br />
Ruan, Xinhua S10:5<br />
Rylander Hagson, Pauline P01:47<br />
S<br />
Saggau, Werner S05:7<br />
Salminen, Ulla-Stina<br />
P01:10, P01:32, P01:39<br />
Samiei, Niloofar P01:41<br />
Sarkar, Nondita P01:27<br />
Sartipy, Ulrik S01:2<br />
Sarunas, Kinduris P01:42<br />
Savasta, Marcello S05:5<br />
Schaarschmidt, Jan S06:4, S06:5<br />
Seeburger, Joerg S06:5<br />
Segadal, Leidulf P01:36, P01:45<br />
Sigfusson, Nikulas P01:18<br />
Sigurdsson, Gisli S10:6<br />
Sigurjonsson, Hannes<br />
P01:06, P01:12, P01:23, S10:6<br />
Simek, Martin P01:07, P01:09<br />
Simonardottir, Liney S06:6<br />
Simpanen, Jarmo P01:38<br />
Sipponen, Jorma P01:10, P01:31<br />
Sisto, Tero S03:1<br />
Sjögren, Johan P01:11<br />
Skindbjerg, Hanne S18:1<br />
Slettebø, Haldor S07:3<br />
Smarason, Njall P01:12<br />
Smerup, Morten<br />
P01:03, P01:04, S01:1<br />
Soefteland, Eirik S07:3<br />
Soisalon-Soininen, Sari P01:39<br />
Sorensen, Gro P01:29, P01:30, S07:4<br />
Souza, Domingos S09:3<br />
Sprogøe, Pia S06:8<br />
Steinbrüchel, Daniel A.<br />
S01:3, S09:1, P01:05<br />
Steingrímsson, Steinn P01:11<br />
Stenseth, Roar S07:5<br />
Strömberg, Anna S07:7<br />
Ståhle, Agneta S18:3<br />
Sundh, Marie P01:47<br />
Suojaranta-Ylinen, Raili P01:22, P01:39<br />
Svalgaard, Marianne S18:1<br />
Svedjeholm, Rolf<br />
P01:24, P01:40, S07:7<br />
Svegby, Henrik P01:08<br />
Sveinsdottir, Herdis S07:8<br />
Svenarud, Peter<br />
P01:08, P01:27, S01:2<br />
Svensson, Gunnar S05:3<br />
Sørensen, Benny S09:6<br />
T<br />
Tamás, Éva<br />
P01:37, P01:43, S05:1, S05:2<br />
Tang, Mariann S03:3, S09:6<br />
Tarkka, Matti S10:5<br />
Terp, Kim S09:6<br />
Thiara, Amrit Singh S06:7<br />
Thimour-Bergström, Linda<br />
P01:01, P01:02<br />
Thorsteinsdottir, Steinunn Arna<br />
P01:46<br />
Thorsteinsson, Hunbogi P01:16<br />
Thorup, Charlotte Brun S18:1<br />
Thuesen, Leif S01:4<br />
Tian, Yikui S10:5<br />
Torfason, Bjarni S06:6<br />
Tornvall, Per P01:27<br />
Tracey, Anita P01:48, P01:50<br />
Tyden, Hans S09:4<br />
U<br />
Urell, Charlotte S18:2<br />
V/W<br />
Wahba, Alexander S07:5<br />
Vainikka, Tiina<br />
P01:10, P01:32, P01:39<br />
Vakkuri, Anne P01:10<br />
Wallby, Lars P01:43, S05:1, S05:2<br />
Walsoe, Charlotte S07:1<br />
Valsson, Felix S06:6<br />
van der Linden, Jan<br />
P01:08, P01:27, S01:2<br />
Wang, Youyu S10:1<br />
Vanky, Farkas P01:24, P01:40<br />
Wei, Minxin S10:5<br />
Wennervirta, Johanna P01:10<br />
Wennman, Susanna S18:3<br />
Vento, Antti P01:39<br />
Werkkala, Kalervo P01:38<br />
Westerdahl, Elisabeth S18:2<br />
Vidarsdottir, Halla S09:2<br />
Wierup, Per S01:1, S09:6<br />
Vigano', Mario S05:5<br />
Wiklund, Claes U S01:6<br />
Virolainen, Juha P01:31<br />
Wirup, Per P01:38<br />
Volt, Martin P01:51<br />
STOCKHOLM, SWEDEN 33<br />
X<br />
Xue, Lei S10:2<br />
Y<br />
Yaghoubi, Nahid P01:26<br />
Yang, Yanqi S10:1, S10:2<br />
Z<br />
Záleaák, Bohumil P01:09<br />
Å<br />
Ågren, Susanna S07:7<br />
Ångerman-Haasmaa, Susanne P01:10<br />
Ö<br />
Önsten, Linda P01:01, S06:2<br />
Övrebö, Bente S06:3
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Epic <br />
Stented Tissue Valve<br />
with Linx AC Technology<br />
FlexFit <br />
Implant System<br />
Advanced Technology <strong>for</strong><br />
Long-Term Durability.<br />
Supported by 20-year published durability data <strong>for</strong> our Biocor valve and 25 years of<br />
Biocor clinical experience, the Epic valve offers the same design as the Biocor valve,<br />
with Linx AC Technology. A patented, proprietary anticalcification treatment, Linx AC<br />
is designed to improve long-term per<strong>for</strong>mance and valve durability.*<br />
For enhanced control during the entire implant procedure, the Epic valve also features<br />
the exclusive FlexFit system.<br />
SJMprofessional.com<br />
*There is no clinical data currently available which evaluates the long-term impact of anticalcification tissue treatment in humans.<br />
Biocor, Epic, FlexFit, Linx, ST. JUDE MEDICAL, the nine-squares symbol and MORE CONTROL. LESS RISK. are trademarks and service marks<br />
of St. Jude Medical, Inc. and its related companies. ©<strong>2009</strong> St. Jude Medical. All Rights Reserved.
ABSTRACTS<br />
STOCKHOLM, SWEDEN 37
S01<br />
<strong>SATS</strong> AWARD NOMINEES ORAL ABSTRACT SESSION<br />
S01:1<br />
IMPACT OF PAPILLARY MUSCLE RELOCATION AS ADJUNCT PROCEDURE TO MITRAL RING<br />
ANNULOPLASTY IN FUNCTIONAL ISCHEMIC MITRAL REGURGITATION<br />
Jensen Henrik 1 , Jensen Morten 2 , Smerup Morten 3 , Wierup Per 3 , Ringgaard Steffen 4 ,<br />
Hasenkam J. Michael 3 , Nielsen Sten Lyager 3<br />
1) Aarhus University Hosptital, Skejby, 2) Aarhus Univ. Dept. of Biomed. Eng.,<br />
3) Aarhus University Hospital, Skejby, 4) Aarhus Univ. Hosp., MRI-Research Centre, Denmark<br />
Background<br />
The optimal surgical treatment in functional ischemic mitral regurgitation(FIMR) remains controversial. Recently, a<br />
posterior papillary muscle relocation(PMR) technique as adjunct procedure to ring annuloplasty has been proposed<br />
to prevent recurrent FIMR. In the present study we used 3D cardiac magnetic resonance imaging to assess the<br />
impact of relocating both papillary muscles as adjunct procedure to down-sized ring annuloplasty on mitral leaflet<br />
coaptation geometry in FIMR pigs.<br />
Methods<br />
Eleven FIMR pigs were randomized to down-sized ring annuloplasty(RA, n= 6) or RA combined with PMR(RA+PMR,<br />
n=5). In the RA+PMR group a 2-0 Gore-tex suture was attached to each trigone, exteriorized through the<br />
corresponding papillary muscle, mounted on an epicardial pad and tightened to relocate the myocardium adjacent to<br />
the anterior and posterior papillary muscles 5 and 15 mm, respectively. Using 3D magnetic resonance imaging the<br />
impact from these interventions on leaflet geometry was assessed.<br />
Results<br />
Following statistically significant(p
S01:3<br />
30-DAY OUTCOMES IN HIGH RISK-PATIENTS RANDOMIZED TO OFF-PUMP OR ON-PUMP CORONARY<br />
BYPASS SURGERY<br />
Møller Christian H 1 , Perko Mario 1 , Lund Jens 1 , Andersen Lars W. 1 , Madsen Jan K. 2 ,<br />
Gluud Christian 1 , Steinbrüchel Daniel A 1<br />
1) Rigshospitalet, 2) Gentofte Hospital, Denmark<br />
Background<br />
Coronary artery bypass grafting (CABG) per<strong>for</strong>med with (on-pump) and without (off-pump) cardiopulmonary bypass<br />
seems safe and results in about the same outcome in low-risk patients. Observational studies indicate that off-pump<br />
surgery may provide more benefit in high-risk patients. Our objective was to compare outcomes in high-risk patients<br />
randomized to CABG with or without cardiopulmonary bypass.<br />
Methods and Results<br />
We randomly assigned 341 patients with a EuroSCORE ≥ 5 and 3-vessel coronary disease to undergo on-pump<br />
versus off-pump CABG. Patients were followed up through the Danish National Patient Registry. The primary<br />
outcome was a composite of adverse cardiac and cerebrovascular events (i.e., all-cause mortality, acute myocardial<br />
infarction, cardiac arrest with successful resuscitation, low cardiac output syndrome/cardiogenic shock, stroke, and<br />
coronary reintervention). An independent event committee blinded <strong>for</strong> treatment allocation assessed the outcomes.<br />
Baseline characteristics were well balanced between groups, and the mean number of grafts per patient did not<br />
differ significantly between groups (3.22 in off-pump and 3.34 in on-pump, P = 0.11). No significant difference in the<br />
composite primary outcome (15% vs 17%, P = 0.48) or the individually components were found at 30-day follow-up.<br />
Fewer grafts were per<strong>for</strong>med to the lateral part of the left ventricle territory during off-pump surgery (0.97 vs 1.14<br />
after on-pump surgery; P = 0.01). Conclusion - Both off- and on-pump CABG can be per<strong>for</strong>med in high-risk patients<br />
with low short-term complications. Off-pump surgery seems to be associated with a reduced number of grafts to the<br />
lateral territory of the left ventricle.<br />
S01:4<br />
CATHETER BASED AORTIC VALVE IMPLANTATION – RESULTS FROM THE FIRST 50 PATIENTS<br />
Nielsen Hans Henrik Møller 1 , Thuesen Leif 1 , Andersen Henning Rud 1 , Hjortdal Vibeke E 1 ,<br />
Klaaborg Kaj-Erik 1 , Jakobsen Carl-Johan 1 , Böing Ingeborg 1<br />
1) Aarhus University Hospital, Skejby, Denmark<br />
Background<br />
Aortic valve stenosis is a common cause of morbidity and mortality among the elderly population. Medical treatment<br />
is often inadequate and most patients ultimately need aortic valve surgery (AVS). Up to one third of patients<br />
requiring AVS is deemed inoperable due to co-morbidities and consequently high risk. At Aarhus University Hospital,<br />
Skejby, catheter based stentvalve implantation have been used to treat selected highrisk patients with aortic valve<br />
stenosis since 2006.<br />
Aim<br />
The aim of this study was to evaluate morbidity and mortality following catheter based aortic valve implantation.<br />
Materials and methods: A total of 50 patients were treated with an aortic<br />
stentvalve between february 2008 and february <strong>2009</strong>. 15 were done via transfemoral (TFA-AVI) technique and<br />
35 via transapical technique (TAP-AVI). Median age of the patients was 83+ 6, 7 and 62% females. Mean logistic<br />
EUROscore was 19, 7% and 17, 5% in the TAP-AVI and TFA-AVI group respectively.<br />
Results<br />
Successful stent valve implantation were per<strong>for</strong>med in 46/50 (92%) patients. The first two patients in this series<br />
died during procedure TFA-AVI. There were no peroperative deaths in the TAP-AVI group. 30 days mortality rate<br />
was 20% in TFA-AVI and 6% in TAP-AVI group. There was no incidence of peroperative MI or coronary occlusion<br />
requiring PCI/CABG.<br />
Conclusion<br />
Catheter based aortic stent valve implantation is a feasible technique, requiring close co-operation between<br />
surgeons, cardiologists and anesthesiologists. The procedure should be reserved <strong>for</strong> selected highrisk patients<br />
deemed inoperable to conventional surgery, until further studies, preferably randomized trials, have documented<br />
the technique.<br />
STOCKHOLM, SWEDEN 39
S01:5<br />
THE NEW TNM STAGING SYSTEM FOR LUNG CANCER - A REVIEW OF 511 PATIENTS OPERATED AT<br />
KAROLINSKA UNIVERSITY HOSPITAL.<br />
Bergman Per 1 , Brodin Daniel 2 , De Petris Luigi 3<br />
1) Dept of Cardiothor Surgery and Anesthesiology, Karolinska, 2) Dept of Lung Medicine, Karolinska,<br />
3) KS Biomic Center, Karolinska Institutet, Sweden<br />
Objective<br />
In spite of diagnostical progress and more systematically lymph node dissection during lung cancer surgery, lung<br />
cancer is still the leading cause of cancer death in both sexes. It is a significant public health problem and has<br />
continuously increased in incidence and particulary in women with 3.6%/year <strong>for</strong> the last decade. The TNM staging<br />
system plays hereby a predominant role in the choice of treatment and <strong>for</strong> the prediction of the prognosis.<br />
Methods<br />
A comparison between the old staging system (sixth edit.) and the new staging system (seventh. edit.) was made<br />
among 511 patients operated <strong>for</strong> lung cancer at Karolinska during 1982-2002. Of particular interest was the median<br />
survival time (Kaplan Meier method) and the difference between the old subgroup IA (tumor size 3 cm) and the new<br />
subgroups IA-a ( 2 cm) and IA-b (>2 - 3 cm). The T-stage (tumor size) is in these groups a decisive factor.<br />
Results<br />
Comparing the old subgroup IA (91 month + 9.6) with the new subgroups IA-a and IA-b, there was a unexpected,<br />
significant difference between the median survival time comparing the new subgroups IA-a (110 month + 8,01)<br />
respectively IA-b (64 month + 6,1) indicating that patients with tumor size > 2 cm have a more severe prognosis<br />
than tumor sized 2 cm. Conclusion: The new staging system seems to better elucidate the prognostic importance of<br />
tumor size than the previous edition. These findings are also in accordance with several other published studies.<br />
S01:6<br />
NON-SELECTIVE CYCLOOXYGENASE (COX) INHIBITION DECREASES SHUNT DURING ONE-LUNG<br />
VENTILATION FOR THORACIC SURGERY.<br />
Rimeika Danguole 1 , Lindahl Sten G 1 , Wiklund Claes U 1<br />
1) Karolinska University Hospital, Sweden<br />
Background<br />
Prostacyclin has been shown to exert modulating effects on hypoxic pulmonary vasoconstriction (HPV). The<br />
purpose of this study was to investigate if cyclooxygenase inhibition decreases shunt fraction and improves arterial<br />
oxygenation during one-lung ventilation (OLV).<br />
Methods<br />
Altogether 32 patients exposed to OLV <strong>for</strong> thoracic surgery were randomly assigned to receive 75 mg diclofenac<br />
or saline intravenously after induction of anesthesia. Measurements were done during two-lung ventilation (TLV)<br />
in supine and lateral position, after 5, 15 and 30 minutes of OLV be<strong>for</strong>e surgical ligation of pulmonary vessels<br />
and finally after TLV was re-established.There were no differences between groups in patient characteristics or<br />
preoperative conditions. Cardiac index, mixed venous oxygen tension, PaCO2 and mean pulmonary arterial pressure<br />
were similar in the groups.<br />
Results<br />
In the placebo group the shunt fraction increased from 12 % during TLV to 37 % at 15 minutes of OLV and 38 %<br />
at 30 minutes of OLV. In the diclofenac treated group shunt fraction increased from 12 % at TLV to 27 % after 15<br />
minutes of OLV and to 29 % at 30 minutes of OLV. Shunt fraction was significantly improved in the diclofenac group<br />
compared with the placebo group, at 15 minutes of OLV (P = 0.043). Conclusion: It was concluded that COXinhibition<br />
with diclofenac augments hypoxic pulmonary vasoconstriction and decreases shunt fraction during OLV<br />
<strong>for</strong> thoracic surgery.<br />
40 www.sats<strong>2009</strong>.org
S03<br />
SATNU ORAL ABSTRACT SESSION<br />
THEME: DEALING WITH PATIENTS’ PHYSICAL POSTOPERATIVE PROBLEMS<br />
S03:1<br />
POSTOPERATIVE NAUSEA AND VOMITING AFTER CARDIAC SURGERY: NURSING POINT OF VIEW<br />
Murkka Timo 1 , Niemi Anu 1 , Järvelä Kati 1 , Maaranen Pasi 1 , Huhtala Heini 2 , Sisto Tero 1 ,<br />
1) Heartcenter/ Pirkanmaa hospital district, 2) Tampere University, Finland<br />
Introduction<br />
Postoperative nausea and vomiting (PONV) is a very distressing adverse event. In this study, we tested the use of<br />
Apfel-score in predicting PONV among male cardiac surgery patients. This score consists of four predictors: female<br />
gender, history of motion sickness or PONV, nonsmoking, and the use of postoperative opioids. We also evaluated<br />
how harmful the patients and the nurses experienced PONV after coronary artery bypass grafting (CABG).<br />
Methods<br />
Fifty men undergoing CABG were interviewed preoperatively. PONV was treated according to a protocol. The<br />
patients were interviewed at the end of ICU stay and on the ward 2-5 days later. The ICU nurses answered a<br />
question: Is PONV a nursing problem in these patients?<br />
Results<br />
Total incidence of PONV was 34.7%. The measured incidences of PONV <strong>for</strong> Apfel-scores 1, 2 and 3 were 22, 41 and<br />
67% while the predicted incidences were 21, 39 and 61%. One third of the patients (32%) did not remember their<br />
ICU stay at all. Only one patient (2%) experienced insufficient treatment <strong>for</strong> PONV. Most of the ICU nurses (88.2%)<br />
did not consider PONV as a nursing problem in our ICU.<br />
Discussion<br />
Apfel-score predicted PONV very well in male cardiac surgery patients. PONV is common in this patient group, but<br />
the ICU nurses did not find it problematic, because they have sufficient tools to treat the patients. The patients were<br />
also satisfied. There<strong>for</strong>e, we are now using even more aggressive treatment protocol.<br />
S03:2<br />
PREDICTION OF THE CONSUMPTION OF OPIOID ANALGESICS FOLLOWING MINIMALLY INVASIVE<br />
CORRECTION OF PECTUS EXCAVATUM<br />
Grosen Kasper 1 , Pilegaard Hans K. 2 , Jensen Mogens P. 3<br />
1) Aarhus University, 2) Aarhus University Hospital, Skejby, 3) Aarhus University Hospital, NBG, Denmark<br />
Background<br />
Minimally invasive correction of pectus excavatum (MIRPE) is primarily per<strong>for</strong>med to obtain cosmetic and<br />
psychological benefits <strong>for</strong> the patient. MIRPE is often associated with postoperative pain management problems.<br />
This study estimates the effect of the severity of pectus excavatum on the postoperative consumption of opioid<br />
analgesics following the minimally invasive procedure in order to optimize pain management.<br />
Methods<br />
A retrospective study was conducted on 236 consecutive patients undergoing MIRPE from 2005-2008. The collected<br />
data included evaluation of preoperative pectus excavation depth, patient demographics, data <strong>for</strong> the peri- and<br />
postoperative period, including data on the pain management. The consumption of opioid analgesics was registered<br />
after discontinuation of epidural analgesia and the various types of opioid analgesics used during the study period<br />
were converted to morphine equivalents.<br />
Results<br />
The total morphine consumption following MIRPE ranged between 20 and 370 mg/day. Multiple linear regression<br />
analysis explained approx. 30% of the variation in log(morphine, mg/day) (R2=0.2957). There was a significant positive<br />
linear relationship between pectus severity and daily consumtion of morphine. Thus, postoperative consumption of<br />
morphine increased by 6% (95% CI: 0.3 to 11%) when preoperative pectus excavatum depth deteriorated with 1 cm.<br />
Conclusion<br />
This study confirms that pectus severity plays a significant role <strong>for</strong> the consumption of opioid analgesics<br />
following MIRPE. We conclude that knowledge of pectus severity might be useful in the prediction of the<br />
expected morphine consumption <strong>for</strong> future patients, especially in the critical transition period going from<br />
epidural analgesia to oral analgesia.<br />
STOCKHOLM, SWEDEN 41
S03:3<br />
GABAPENTIN FOR POSTOPERATIVE PAIN MANAGEMENT AFTER CARDIAC SURGERY WITH MEDIAN<br />
STERNOTOMY<br />
Laursen Vibeke 1 , Tang Mariann 2 , Parvaiz Imran 3 , Hjortdal Vibeke 2<br />
1) Aarhus University Hospital, Skejby, 2) Department of Cardiothoracic Surgery,SKS,<br />
3) Department of Cardiacthoracic Surgery,RH, Denmark<br />
Introduction<br />
Cardiac surgery with sternotomy is a major surgical trauma. The surgical injury and anaestesia is followed by pain,<br />
postoperative nausea and vomiting (PONV). Pain relief after surgery is prerequisite <strong>for</strong> moblisation and early return<br />
to pre-surgical level. The preferred drug <strong>for</strong> postoperative pain management is opioids which are known to have<br />
a series of side effects such as nausea, vomiting, constipation and delirium. More than one third of the patients<br />
experience PONV after cardiac surgery. PONV is associated with longer stay in post-anaesthesia care and may<br />
cause dehydration and prolonged recovery. Gabapentin was originally developed to treat spasticity but during the<br />
last decade more publications and reports have documented pain relief with use of Gabapentin. Hence no studies<br />
have evaluated Gabapentin as postoperative pain management after cardiac surgery.<br />
Aim/hypothesis<br />
To examine the effect of Gabapentin on postoperative pain after cardiac surgery with the hypothesis being that<br />
Gabapentin is an effective analgesic <strong>for</strong> postoperative pain and has a opioid sparing effect.<br />
Materials & Methods<br />
A clinical randomized, controlled and double blind study including 64 patients scheduled <strong>for</strong> cardiac surgery with<br />
median sternotomy. Patients were randomized to either placebo or gabapentin. The dosage of gabapentin was 1200<br />
mg on the day of surgery and 300 mg twice a day <strong>for</strong> the following five days. Four times a day the patients did pain<br />
assessment with Visual Analogue Score and PONV assessment.<br />
Results<br />
Data are being processed.<br />
S03:4<br />
THE EFFECT OF SOOTHING MUSIC IN RESPONSE TO STRESS AND RELAXATION DURING BED REST<br />
AFTER OPEN-HEART SURGERY<br />
Nilsson Ulrica 1<br />
1) Centre of Health Care Sciences, Sweden<br />
Music interventions have been evaluated as an appropriate intervention to reduce pain, stress and anxiety in<br />
a number of clinical settings. A new challenge is to study if music also can influence relaxation system that<br />
incorporates oxytocin.<br />
Aim<br />
To evaluate the effect of bed rest with music on stress and relaxation <strong>for</strong> patients who had undergone heart surgery<br />
on postoperative day one.<br />
Method<br />
Fifty-eight patients who had randomly allocated to either music listening during bed rest or bed rest only. The music<br />
was distributed through a music pillow connected to a MP3 player and the music, MusiCure, was soft, relaxing, and<br />
included different melodies of 60 to 80 bpm and was played <strong>for</strong> 30 minutes with a volume of 50-60 dB. Stress and<br />
relaxation response was assessed by s-cortisol, s-oxytocin, heart rate, respiratory rate, MAP, PaO2 , SaO2 and<br />
subjective pain, anxiety and relaxation levels. Results: In the music group levels of oxytocin increased significantly in<br />
contrast to the control group <strong>for</strong> which the trend over time was negative i.e. decreasing values. Subjective relaxation<br />
levels increased significantly more and there were also a significant higher levels of PaO2. After 30 minutes there<br />
was a significantly less s-cortisol levels in the music group. There was no difference in MAP, heart rate and SaO2<br />
between the groups.<br />
Conclusion<br />
Music intervention should bee used as an integral part of the multimodal regime administered to the patients that<br />
have undergone cardiovascular surgery.<br />
42 www.sats<strong>2009</strong>.org
S03:5<br />
NURSEMANAGED INSULIN PROTOCOL IMPROVES TREATMENT OF HYPERGLYCAEMIA IN PATIENTS<br />
WITH DIABETES UNDERGOING OPEN HEART SURGERY<br />
Lange Aase 1<br />
1) Aarhus University Hospital Skejby, Denmark<br />
Background<br />
Strict glycemic control in critically ill patients is challeging <strong>for</strong> both nurses and physicians. Studies Have shown<br />
that aggressive glycemic control by a nursemanaged subcutaneous insulin protocol outside ICU improves mortality<br />
and morbidity as well as efficiency and safety. An audit made in 2006 at the Department of Cardiothoratic<br />
Surgery at Aarhus University Hospital Skejby, Denmark showed that only 62 % of patients with hyperglycemia<br />
were treated according to recommendations. The low compliance was presumably due to fear of hypoglycaemia<br />
and lack of knowledge.<br />
Objectives<br />
To determine the effect of focused education of nurses followed by implementation of a nursemanaged insulin protocol.<br />
Methods<br />
Intensive education of nurses followed by development and implementation of a nursemanaged insulin protocol. Two<br />
audits to determine if hyperglycaemia was treated according to the implemented insulin protocol. Blood glucose<br />
levels and insulin doses per day were documented in 15 patients be<strong>for</strong>e and in 15 patients after implementation of<br />
the protocol.<br />
Results<br />
Audit in 2006: number of measured hyperglycaemia values in 15 patients was 105 and 62 % were treated according<br />
to reccommendations. Audit in <strong>2009</strong>: number of measured hyperglycaemia values in 15 patients after implementation<br />
of insulin protocol was 263 and 90,5 % were treated according to the nursemanaged insulin protocol.<br />
Conclusions<br />
Intensive education followed by development and implementation of a nursemanaged insulin protocol has increadsed<br />
compliance and led to a considerable improvement in the treatment of hyperglycaemia. Potentially this could lead to<br />
improved mortality and morbidity <strong>for</strong> this patientgroup.<br />
S03:6<br />
PREVALANCE OF POSTOPERATIVE PROBLEMS AMONG DANISH HEART-OPERATED PATIENTS<br />
14 DAYS AFTER DISCHARGE FROM HOSPITAL<br />
Ibsen Dorthe 1 , Greve Helle 1<br />
1) Rigshospitalet, Denmark<br />
Background<br />
Several patients call the heart-surgery ward because they don’t know where to address problems related to dyspnoea,<br />
medication, and infections. International research documents that many heart-operated patients experience<br />
emotional and physiological problems one year after their operation. The aim of this study is to gain knowledge<br />
about Danish heart-operated patients´ experience of these problems during the first 14 days after discharge from<br />
hospital, to uncover if the constructed questionnaire is useful to gain in<strong>for</strong>mation about this, and as background <strong>for</strong><br />
a clarifying telephone interview.<br />
Method<br />
Data was acquired by use of a semistructured questionnaire, followed up by telephone-interviews. 9 patients were<br />
asked to complete the questionnaire, and to participate in the interview 14 days after discharge. The results are<br />
preliminary as the study is not yet completed. 8 patients participated in the study, 6 males and 2 females, age<br />
between 50-72 years. 6/8 experienced depression in the first 7-14 days, 7/8 pain, 6/8 sleeping problems, 6/8 lack<br />
of energy.<br />
Conclusions<br />
Danish heart surgery patients seem to have the same emotional and physiological problems during the first 14 days<br />
after discharge, as shown in international research. The semistructured questionnaire and telephone interviews<br />
<strong>for</strong>med a basis <strong>for</strong> gaining knowledge of patients’ problems during the first 14 days at home. According to the<br />
preliminary results it seems important that nurses call their patients after discharge, and individualize the discharge<br />
dialogue to make sure that patients are more capable to act adequate upon the challenges, experienced after their<br />
discharge from hospital.<br />
STOCKHOLM, SWEDEN 43
S05<br />
<strong>SATS</strong> CARDIAC ORAL ABSTRACT SESSION<br />
S05:1<br />
INITIAL EXPERIENCE WITH A CATHETER BASED AORTIC VALVE IMPLANTATION SYSTEM.<br />
Ahn Henrik 1 , Baranowski Jacek 1 , Freter Wolfgang 1 , Nielsen Niels Erik 1 , Nylander Eva 1 , Wallby Lars 1 , Tamas Eva 1<br />
1) Linköping Heart Center, Sweden<br />
Fifteen patients (pts), 9 females and 6 males, mean age 78 (60-91) years were selected <strong>for</strong> transcatheter aortic<br />
valve implantation. The pts were evaluated according to our regular routines and denied <strong>for</strong> open chest surgery<br />
due to high risk profile with logistic Euroscore 22 (7-45) % and STS score 19 (10-30). Mean maximal velocity<br />
(Vmax) was 4.8 (3.8–6.5) m/s, the mean gradient was 60 (33-108) mmHg and the mean aortic valve area was<br />
0.5 (0.4–0.8) cm2.<br />
Methods<br />
All procedures were carried out in general anesthesia using the Sapien valve (Edwards Lifesciences). Ten transapical<br />
and 5 transfemoral implants were per<strong>for</strong>med.<br />
Results<br />
All implantations (8 valves 26 mm and 7 valves 23 mm) were successful. Blood pressure failed to recover in 2<br />
pts following rapid pacing necessitating CPR with good recovery. However, 2 pts suffered from renal failure, one<br />
needing dialysis.<br />
One pt got a postoperative pericardial effusion. The 30-day mortality was 1/15 pts as well as the 90-day mortality.<br />
The residual aortic valve leaks (central and paravalvular) were small in all pts. Post-implant mean Vmax was 2.4<br />
(1.5–2.9) m/s and the mean gradient was 15 (4-37) mmHg. The mean ICU-stay was 2.6 (1-18) days. Pts were<br />
discharged after 10 (4-18) days.<br />
Conclusion<br />
This new technology worked well in our hands and the procedure was per<strong>for</strong>med with reproducible and acceptable<br />
results. The patient selection is a challenge since serious comorbidity can impair results, disguising the potential of<br />
this promising technology. The long-term results will be the most important endpoints.<br />
S05:2<br />
ECHO-GUIDED PRESENTATION OF AORTIC VALVE MINIMISES CONTRAST MEDIUM EXPOSURE IN<br />
SAPIEN AORTIC VALVE RECIPIENTS.<br />
Baranowski Jacek 1 , Ahn Henrik 1 , Freter Wolfgang 1 , Nielsen Niels Erik 1 , Nylander Eva 1 , Tamas Eva 1 , Wallby Lars 1<br />
1) Linköping Heart Center, Sweden<br />
During Sapien aortic valve prothesis implantation a perpendicular position of the aortic valve to the radiation beam<br />
is a sine-qua-non <strong>for</strong> the optimal prosthesis delivery. This right valve-beam-angle is expected to lower risks <strong>for</strong><br />
proximal and distal embolisation of the protheses, reststenosis, coronary artery occlusion, and AV-block occurrence.<br />
The current gold standard to achieve this optimal angle is to use repeated aortic aortograms. The Sapien valve<br />
candidates often have reduced renal function with contrast exposure being an important factor <strong>for</strong> their recovery.<br />
Material and methods<br />
Transcatheter Sapien aortic valve prostheses have been implanted in 15 patients. Various methods <strong>for</strong> perpendicular<br />
valve presentation during fluoroscopy were employed: statistical chance, CT, repeated ascendens aortograms and<br />
transthoracic echo-guided presentation in a new Linköping design.<br />
Results<br />
Statistical chance and CT have failed to be of help during the procedure. Repeated ascendens aortograms make<br />
the procedure feasible with the price of high contrast volumes and long fluoroscopy times. The transthoracic echoguided<br />
presentation resulted in a dramatic decrease in contrast ( from 223 ml/ procedure to 69 ml/procedure) and<br />
some in radiation exposure to the patients during the procedure.<br />
Conclusion<br />
Our echo-guided method <strong>for</strong> perpendicular aortic valve position lowers significantly the contrast media exposure in<br />
the fragile population of transcatheter aortic prosthesis recipients.<br />
44 www.sats<strong>2009</strong>.org
S05:3<br />
SURVIVAL AND QUALITY OF LIFE AFTER AORTIC ROOT REPLACEMENT WITH CRYOPRESERVED<br />
HOMOGRAFTS IN ACUTE ENDOCARDITIS<br />
Perrotta Sossio 1 , Aljassim Obaid 1 , Bech-hanssen Odd 1 , Jeppsson Anders 1 , Svensson Gunnar 1<br />
1) Sahlgrenska University Hospital, Sweden<br />
Background<br />
Aortic root replacement with homograft is a theoretically attractive but technically demanding option in patients with<br />
infective endocarditis, especially in patients with subvalvular abscesses and/or prosthetic endocarditis. We report<br />
our midterm experience with cryopreserved homografts in acute infective aortic endocarditis.<br />
Methods<br />
All 62 patients operated with aortic homograft <strong>for</strong> severe acute aortic endocarditis between 1997 and June 2008 were<br />
retrospectively analysed. Fifty two (84%) had subvalvular abscesses. 24 patients (39%) had prosthetic endocarditis.<br />
Survival, perioperative complications, re-operations and quality of life (SF 36) were assessed. Mean follow-up was<br />
3.1 years (range 0 12).<br />
Results<br />
Nine patients (14%) died within 30 days. Pre and perioperative variables univariately associated with early<br />
mortality were CPB-time (p=0.003), prolonged inotropic support (p=0.03), reoperation <strong>for</strong> bleeding (p=0.01) and<br />
perioperative myocardial infarction (p
S05:5<br />
MINIMALLY INVASIVE REOPERATIVE AORTIC VALVE SURGERY WITH PATENT CORONARY ARTERY<br />
BYPASS GRAFTS<br />
Raffa Giuseppe 1 , Pellegrini Carlo 2 , Savasta Marcello 2 , Pozzi Matteo 2 , Vigano’ Mario 2<br />
1) The Salam Centre <strong>for</strong> Cardiac Surgery, Sudan 2) University of Pavia, Italy<br />
Objective<br />
Cardiac reoperations are associated with higher morbidity and mortality mainly due to the risk of damaging cardiac<br />
structures. Minimally invasive techniques may reduce the surgical risks.<br />
Methods<br />
Since 1997, more than 1000 mini-sternotomies have been per<strong>for</strong>med at our department. Out of these, seventeen<br />
patients (15 males, 2 females, mean age: 68.7 years) had a patent graft on LAD. Mean ejection fraction was<br />
45% and NYHA class 2.7. Fifteen patients underwent native aortic valve replacement, whereas in two patients a<br />
malfunctioning valve prosthesis was replaced.<br />
Results<br />
Mean cardiopulmonary and aortic cross clamp time were 119.7±38.1 (range: 50-235) and 72±20 (range: 45-125)<br />
minutes, respectively. Mean cooling body temperature was 27.4 (°C). Antegrade cold crystalloid cardioplegia was<br />
delivered to all the patients. LIMA injury occurred in one patient and caused perioperative myocardial infarction,<br />
low cardiac output syndrome requiring intraaortic balloon pump and, eventually, hospital death (5.9%). Neither<br />
conversion to full sternotomy nor reoperation <strong>for</strong> bleeding occurred. Mean bleeding was 426±474 ml (range: 120-<br />
1950). Mean postoperative ICU and hospital stay were 1.6±1.1 and 7.5±2.6 days, respectively. Postoperative<br />
course was totally uneventful in ten patients (58.8%). Follow-up was complete <strong>for</strong> a total of 928 patient/months<br />
(range: 11-124): four late deaths occurred, two related to cardiac causes. Prosthesis related morbidity did not occur<br />
either early or late. Nine of the 12 survivors (75 %) are in NYHA class II.<br />
Conclusions<br />
Considering the low complication rate, a minimally invasive access in the presence of patent coronary artery grafts<br />
may represent a preferential surgical approach.<br />
S05:6<br />
HYPOTHYROIDISM IN CARDIAC SURGERY PATIENTS. A SINGLE UNIT FOLLOW-UP.<br />
Jyrala Aarne 1 , Kay Gregory L 1<br />
1) United States<br />
The aim of this study is to analyze patient presentation, early and late outcomes in patients with hypothyroidism (HT)<br />
compared to patients matched by age, gender and type of surgery.<br />
Of 1000 consecutive cardiac surgery patients operated between Jan 1999 and May 2000 80 pts had a diagnosis of<br />
HT (Group 1); 80 matched pts were identified from the database (Group 2).<br />
Additive EuroSCORE (ES) did not differ between the groups but logistic ES did (p=0.05). The proportion of very<br />
high-risk pts (log ES >25%) was higher in Group 1 (24.1% vs 17.7%), more pts had CHF (43.8%vs36.3%), had<br />
diabetes (43.8%vs35.0%), were in NYHA class III-IV (66.4%-55.0%) or had AF (16.5% vs 0 %).<br />
There were no operative deaths. Hospital mortality was similar. New AF occurred in 23.0 % of pts in Group 1 and in<br />
9.2% in Group 2. There were more pts in Group 1 with prolonged hospital stay (>10 days, 28.4% vs 18.3%) and 4<br />
times more pts in Group 1 needed extended care or rehabilitation after discharge. All-cause follow-up mortality (up<br />
to 107 months) was higher in Group 1 (43.0% vs 30.4%). 2 pts died in the postoperative period due to untreated HT.<br />
All comparisons have p-value 0.05 or lower.<br />
Conclusions<br />
HT pts are sicker at presentation than controls, their resource utilization is higher and survival lower. Occurrence of<br />
postoperative AF is considerably higher. Although there were no operative deaths and hospital mortality was similar,<br />
postoperative deaths occurred when HT was not adequately treated.<br />
46 www.sats<strong>2009</strong>.org
S05:7<br />
CONTINUOUS VENOVENOUS HEMODIALYSIS (CVVHD) WITH CITRATE CALCIUM REDUCES<br />
POSTOPERATIVE BLEEDING COMPLICATIONS AFTER CARDIAC SURGERY<br />
Kiessling Arndt-h. 1 , Neher Michael 1 , Kornberger Angela 1 , Lehmann Andreas 1 , Raoul Bergner 1 ,<br />
Isgro Frank 1 , Saggau Werner 1<br />
1) Klinikum Ludwigshafen, Germany<br />
Objective<br />
Continuous renal replacement therapy is the preferred method of treatment of acute renal failure after cardiac<br />
surgery. Efficient anticoagulation of the extracorporeal circulation is essential to prevent clotting of the system.<br />
Regional anticoagulation using citrate is assumed to reduce the risk of systemic bleeding. The present study<br />
investigates the safety of citrate dialysis (CI-CA) after cardiac surgery in comparison with conventional procedures<br />
using heparin (HEP).<br />
Methods<br />
In a prospective randomized, non-blinded monocentric trial (11/2008-02/<strong>2009</strong>), we compared continuous venovenous<br />
hemodialysis (CVVHD) using heparin (Diapact CRRT B.Braun AG, Germany) (n=26) against a citrate calcium<br />
method (Ci-Ca multifiltrate Fresenius Medical Care, Germany) (n =24). In the HEP group, the system was primed<br />
with 600 IE heparin and run with a minimum of 15000IE/24h of heparin on the basis of HEP test controls (0.4-0.7).<br />
Our primary end points were bleeding events, death, cardiac arrhythmia, creatinine levels and filter occlusion.<br />
Results<br />
There were no differences between the demographic data of the patient groups and no significant difference as<br />
far as the surgical procedures per<strong>for</strong>med and postoperative catecholamine support are concerned. The incidence<br />
of bleeding was significant higher in the HEP group. No differences were found <strong>for</strong> the items: mortality, ICU stay,<br />
respirator time and arrhythmias.<br />
Conclusion<br />
CiCA proved effective and safe. A significant prolongation of filter patency was noted. A significant difference in<br />
mortality was not registered within the small study population. Changes of plasmatic calcium levels representing a<br />
potential risk of cardiac arrhythmia or cardiac output reduction did not occur.<br />
STOCKHOLM, SWEDEN 47
S06<br />
SCANSECT ORAL ABSTRACT SESSION<br />
S06:1<br />
FIBRINOGEN AND THE ACUTE INFLAMMATORY RESPONSE AFTER CARDIAC SURGERY<br />
Kalabic Maria 1 , Jeppsson Anders 1 , Rexius Helena 1<br />
1) Sahlgrenska University Hospital, Sweden<br />
Objective<br />
Fibrinogen concentrate can be used to prevent or treat bleeding after cardiac surgery but it may also raise plasma<br />
concentrations to supra-normal levels, potentially leading to hypercoagulability. Fibrinogen is an acute phase reactant<br />
and plasma concentration increases in response to the surgical trauma. The aim of the study was to establish the<br />
normal response of fibrinogen to cardiac surgery and its potential association to other acute phase reactants.<br />
Methods<br />
Fifteen on-pump CABG patients were included in a prospective observational study. Plasma concentrations of<br />
fibrinogen, C-reactive protein (CRP) and interleukin-6 (IL-6) were measured be<strong>for</strong>e surgery (baseline) and day 1 to<br />
day 4 after surgery. Plasma concentrations at the different time points were compared to baseline and correlation<br />
calculations between fibrinogen, CRP and IL-6 were per<strong>for</strong>med.<br />
Results<br />
Fibrinogen plasma concentration increased during the study period from 3.9±0.6 to 7.8±1.9 g/L (p
S06:2<br />
PLATELET AGGREGABILITY BEFORE AND AFTER CORONARY ARTERY BYPASS SURGERY<br />
Önsten Linda 1 , Jeppsson Anders 1 , Rexius Helena 1<br />
1) Sahlgrenska University Hospital, Sweden<br />
Objective<br />
Platelet dysfunction may contribute to bleeding complications after Coronary artery bypass grafting (CABG).<br />
Impedance aggregometry is a new point-of-care method to assess platelet function. We determined platelet<br />
impedance aggregation be<strong>for</strong>e and after CABG surgery.<br />
Methods<br />
10 patients treated with aspirin and adenosine-diphosphate (ADP) receptor blocker clopidogrel and 9 patients treated<br />
with aspirin within 7 days be<strong>for</strong>e surgery were included in this prospective observational study. Platelet aggregation<br />
was compared between individual time points and between patients with or without clopidogrel treatment. Impedance<br />
aggregometry (Multiplate�), with ADP and thrombin receptor activated peptide 6 (TRAP) as activators.<br />
Results<br />
ADP-induced platelet aggregation at sternum closure was reduced compared to the day be<strong>for</strong>e surgery, to anesthesia<br />
induction and to the day after surgery (20±15 units vs. 41±24, 36±17 and 43±18, respectively (p
S06:4<br />
IN VITRO COMPARISON OF THE NEW IN-LINE MONITOR BMU 40 VS. THE CONVENTIONAL<br />
LABORATORY ANALYSER ABL 700<br />
Grosse F. Oliver 1 , Holzhey David 2 , Falk Volkmar 2 , Schaarschmidt Jan 1 , Kraemer Klaus 1 , Mohr Friedrich Wilhelm 1<br />
1) University of Leipzig - Heart Center, Germany 2) University Hospital, Zurich, Switzerland<br />
Background<br />
Reliable in<strong>for</strong>mation about different blood parameters is essential maintaining haemodynamics, perfusion and gas<br />
exchange during CPB. For this purpose a precise and continuous monitoring is needed. The objective of this in vitro<br />
study was to compare a novel continuous in-line blood parameter monitoring system (CIBPMS) vs. a reference<br />
laboratory analyser.<br />
Methods<br />
The study was conducted as an in vitro prospective experimental study during a CPB simulation. The reliability of<br />
BMU 40 was tested in monitoring the pO2, SO2 and Hct under physiological and extreme conditions with regards<br />
to temperature, oxygenation and blood concentration. Four different tests were per<strong>for</strong>med and conducted with five<br />
sensors each. Correlation analyses and Bland-Altman analyses were per<strong>for</strong>med.<br />
Results<br />
A total of 350 measurement points were compared. All monitored values of blood parameters correlated highly with<br />
laboratory values (all r values > 0.90). Test 1: Biases of pO2(act) vary from -3.24 (±6.86) up to 6.0 (±17.89). The<br />
biases of pO2(37°C) ranged from -3.08 (±5.53) up to 68.8 (±67.82). Test 2: The biases (SD) <strong>for</strong> Hct ranged from<br />
-0.35 (±0.79) up to 2.35 (±0.91). The biases (SD) <strong>for</strong> SO2 vary from -0.45 (±0.86) up to 0.85 (±1.01). Test 3: The<br />
biases (SD) of Hct ranged from -0.67 (±1.49) up to -1.00 (±1.84). Test 4: The biases (SD) <strong>for</strong> SO2 vary from -0.36<br />
(±1.60) up to 0.48 (±0.90).<br />
Conclusions<br />
The BMU 40 is a reliable device in measuring the pO2, SO2 and Hct under normal physiological and extreme<br />
conditions with regards to temperature, oxygenation and blood concentration in simulation of CPB. The algorithm to<br />
calculate pO2(37°) under hypothermic conditions need to be adjusted.*<br />
*In the meantime a new software version of the BMU 40 has been developed. The algorithm to calculate pO2(37°)<br />
under hypothermic conditions has been improved and the miscalculation eliminated.<br />
S06:5<br />
CLINICAL EVALUATION OF THE NEW BMU 40 IN-LINE BLOOD ANALYSIS MONITOR<br />
Schaarschmidt Jan 1 , Borger Michael Andrew 1 , Seeburger Joerg 1 , Grosse Frank Oliver 1 ,<br />
Kraemer Klaus 1 , Mohr Friedrich Wilhelm 1<br />
1) University of Leipzig, Heart Center, Germany<br />
Background<br />
Accurate in<strong>for</strong>mation about different blood parameters is essential in maintaining haemodynamics, perfusion and<br />
gas exchange during cardiopulmonary bypass (CPB). For this purpose a precise and continuous measurement and<br />
monitoring, which is preferably visually available, is needed. The objective of this clinical study was to compare<br />
the newly developed continuous in-line blood parameter monitoring system (CIBPMS) BMU 40, based on optical<br />
luminescence and reflectance technology, with a reference laboratory analyser with regards to the precision of blood<br />
parameters measurement.<br />
Methods<br />
Thirty adult patients underwent elective cardiac surgery utilizing CPB and mild hypothermia (32°C). At five<br />
predetermined time points (S1 – S5) arterial and venous blood samples were analysed using the BMU 40 <strong>for</strong> five<br />
different parameters (paO2(37°C), paO2(act.), SvO2, Hb(ven) and Hct(ven)) and these results were compared to<br />
the gold standard laboratory analyser ABL 700.<br />
Results<br />
A total of 150 paired blood samples were included to compare means, to analyse correlation, to calculate measures<br />
of bias, precision, limits of agreement and 95% confidence intervals. Results revealed good agreement between the<br />
two devices <strong>for</strong> all parameters. Bias ± precision of S2 – S5 paO2(37°C) were 2.17 ± 9.61; paO2(act) 2.58 ± 9.54;<br />
SvO2 -1.44 ± 2.35; Hb(ven) 0.01 ± 0.42; Hct(ven) 0.04 ± 1.29. Statistically significant differences were detected<br />
<strong>for</strong> SvO2 (p
S06:6<br />
ECMO - THE ICELANDIC EXPERIENCE<br />
Astradsson Thorsteinn 1 , Torfason Bjarni 1 , Gudbjartsson Tomas 1 , Simonardottir Liney 1 , Valsson Felix 1<br />
1) Landspitali University Hospital, Iceland<br />
Background<br />
Extracorporeal membrane oxygenation (ECMO) can prove lifesaving in severe respiratory failure (ARDS) and<br />
cardiac failure (CF) refractory to conventional treatment. Because of the complicity and potential complications,<br />
ECMO treatment has been limited to larger medical centers.<br />
Aim<br />
This study evaluates ECMO treatment in Iceland a small and relatively isolated community.<br />
Results<br />
18 patients have been treated with ECMO in Iceland from 1991. Nine of those had ARDS while the other 9 had<br />
CF. Survival rate was 56% <strong>for</strong> both groups, the mean age of ARDS survivors was 20 compared to 50 years <strong>for</strong><br />
non-survivors while the mean age of CF survivors was 33 vs 49 years <strong>for</strong> the non-survivors. Mean pre-ECMO<br />
ventilator time <strong>for</strong> ARDS survivors was 5,2 days (0,5-18) compared to 9,8 days (1-14) <strong>for</strong> ARDS non-survivors. One<br />
of four ARDS patients with a pre-ECMO ventilator time longer than 7 days survived and four of five patient with<br />
pre-ECMO ventilator time less than 7 days survived. CF survivors had lower APACHE II scores than non-surviving<br />
CF patients (14 vs 32). One patient died from hemorrhage related to anticoagulation, while three other patients<br />
survived significant hemorrhage. Recombinant factor VIIa was given to two patients both of which survived. All other<br />
non-survivors succumbed to their underlying diseases.<br />
Discussion<br />
Survival rates (56%) in Iceland are similar to those seen in recent publications. No age limit or pre-ECMO ventilator<br />
time limit has been implemented in Iceland. A stricter protocol regarding age and pre-ECMO ventilator time will be<br />
en<strong>for</strong>ced in future ECMO candidates in Iceland.<br />
S06:7<br />
EXTRACORPOREAL MEMBRANE OXYGENATION SUPPORT FOR 59 DAYS WITHOUT CHANGING THE<br />
ECMO CIRCUIT<br />
Thiara Amrit Singh 1 , Høyland Vivian 1 , Norum Hilde 1 , Aasmundstad Tor 1 , Karlsen Harald 1 , Fiane Arnt 1 , Geiran Odd 1<br />
1) Rikshospitalet, Norway<br />
Background<br />
Veno-venous extracorporeal membrane oxygenation is an established support <strong>for</strong> the treatment of respiratory<br />
failure. We report the successful use of veno-venous ECMO in a 53 year old patient with Legionella pneumonia and<br />
acute respiratory distress syndrome (ARDS) with severe barotraumas.<br />
He was admitted to intensive care unit. His clinical course deteriorated, despite the continuous support with<br />
mechanical ventilation.<br />
Interventions<br />
He was placed on veno-venous ECMO <strong>for</strong> lung rest and while awaiting a response to continued medical treatment.<br />
He was supported by ECMO <strong>for</strong> 59 days without any changes in the ECMO circuit. There were no complications<br />
with the ECMO circuit during the support period.<br />
Conclusion<br />
ECMO can provide a chance of survival even in severe case of ARDS. This is likely the longest support ever reported<br />
using the same oxygenator.<br />
STOCKHOLM, SWEDEN 51
S06:8<br />
COAGULATION IN OXYGENATOR AND ARTERIAL FILTER AFTER RECIRCULATION<br />
Bellaiche Anne Louise 1 , Nielsen Peter Fast 1 , Sprogøe Pia 1 , Klungreseth Oddvar 1<br />
1) Aarhus University Hospital Skejby, Denmark<br />
We report a case of multiple coagulation in two successive oxygenators and one arterial filter when restarting<br />
bypass after 3 hours of recirculation. The case involves emergency surgery <strong>for</strong> dissection of the aorta with insertion<br />
of a homograft using 18 min. of deep hypothermic circulatory arrest and 4 hours of CPB. Bypass is terminated and<br />
protamin administered. Over the following three hours the bypass circuit is circulating while remaining bleeding<br />
is seeked managed surgically and with blood products, cryoprecipitate, haemocompletan and NovoSeven. Going<br />
back on bypass, clots are observed in the oxygenator which is replaced. After initiation of the second bypass period<br />
the arterial filter also shows clotting and is replaced. There is persistent high pressure in the whole circuit,- but<br />
no other clots could be determined at this point. After 1½ hours of bypass, shortly be<strong>for</strong>e weaning, new clots are<br />
observed in the second oxygenator. Bypass is terminated shortly after without problems. ACTs levels measured at<br />
half-hour intervals during the two bypass periods were all above the lower limit (400 sec. measured by Hemochron<br />
Jr) according to our protocol. Two days post-operatively the patient developed dilated pupils. CT scan shows brain<br />
infarction and the patient passed away the next day. Autopsy was not per<strong>for</strong>med. Clots from the circuit could be a<br />
possible cause of the brain damage, however, other explanations are also possible. We present this case <strong>for</strong> peer<br />
discussion with the aim of avoiding similar incidents in the future.<br />
52 www.sats<strong>2009</strong>.org
S07<br />
SATNU ORAL ABSTRACT SESSION<br />
S07:1<br />
HOW DOES NURSING COMPETENCE EXPRESS ITSELF IN THE OPERATING ROOM ?<br />
Walsoe Charlotte 1<br />
1) The Heart Centre, Rigshospitalet, Denmark<br />
An ongoing shortage of nurses in the operating room and generel recruitment difficulties challenges the Danish<br />
health system. As the shortage will continue in the years to come, politicians question the neccesity of exclusively<br />
nurses in the operating room and want to solve the situation by employing staff with a different education. The<br />
operating room nurses have no tradition documenting the essence and quality of nursing, and consequently now<br />
stand with a serious challenge in the discussion of the importance of nurses and nursing in the operating room.<br />
A study was conducted with the question “How does nursing competence and quality express itself in the operating<br />
room? ”.<br />
A search in CINAHL, PubMed and SweMed+ using the terms “nursing and operating room” resulted in 8 qualified<br />
articles, which have been used in this study.<br />
Patricia Benner was used in the theoretical analysis of the articles regarding the competence and essence of nursing<br />
in the operating room.<br />
Theories of the patients’ course of stay in hospital and quality control were used in the study.<br />
The nursing competence express itself in:<br />
- Caring - caring and technology are combined inseparable partners.<br />
- Congruity and continuity during the patients’ course of stay in hospital – the patients should recieve the same kind<br />
of nursing goals, vision and perspective throughout the course of their stay in hospital.<br />
- Safety and quality control – nurses must continously focus on development and an Evidence based practice.<br />
S07:2<br />
THE OPERATING ROOM NURSES EXPERIENCES OF THE MEDICAL EQUIPMENT IN THEIR DAILY WORK<br />
Roman-Emanuel Christine 1 , Hägglund Doris 2<br />
1) Sahlgrenska University Hospital, 2) Örebro University, Sweden<br />
Objective<br />
In the operating team, the operating room nurses are responsible <strong>for</strong> handling and maintenance of the medical<br />
equipment. The knowledge about the operating room nurse’s apprehension of work with medical equipment is<br />
limited. Increased knowledge in this area may increase nurse’s understanding of their role and ultimately, patient<br />
safety. The aim of this study was to describe how the operating room nurse’s experience the importance of the<br />
medical equipment in their daily work and their competence in medical equipment.<br />
Methods<br />
Forty-six operating room nurses working at a University Hospital were included in a prospective qualitative study.<br />
37/46 answered the questionnaire with tree open-ended questions. The answers of the questionnaire were analysed<br />
through a qualitative content analysis method according to Graneheim and Lundmann.<br />
Results<br />
The results demonstrated three main themes. The first theme described an increased understanding of how important<br />
it is to keep up your own competence within the field to ensure patient safety. The second theme described that the<br />
operating room nurse apprehend herself as a key-person in the operating-room teamwork with medical equipment.<br />
The third theme described positive and negative effects of the operating room nurse’s role as responsible <strong>for</strong> the<br />
medical equipment on the working-environment.<br />
Conclusion<br />
The main conclusion is that the competence level of operating room nurses and their experiences of medical<br />
equipment in their daily work influences safety <strong>for</strong> the patient, nursing and teamwork in the operating ward.<br />
STOCKHOLM, SWEDEN 53
S07:3<br />
SURGICAL TEAM MEMBER’S EXPERIENCES, ROUTINES AND VIEWS BEFORE IMPLEMENTATION OF<br />
A TIME-OUT PROTOCOL<br />
Murugesh Shamini 1 , Haugen Arvid 1 , Haaverstad Rune 1 , Slettebø Haldor 1 , Daavoy Grethe 1 , Soefteland Eirik 1<br />
1) Haukeland University Hospital, Norway<br />
Background<br />
Ensuring (1) correct patient (2) correct surgical procedure and (3) correct anatomic site/side <strong>for</strong> surgery is of prime<br />
importance <strong>for</strong> patient safety and may avoid medico-legal cases. Several studies confirm that a “Time-out” be<strong>for</strong>e<br />
the surgical incision can reduce the risk of making mistakes. The objective was to study the medical personnel’s<br />
experiences and views be<strong>for</strong>e implementation of a “Time-out” protocol in our Central Operation Unit (COU).<br />
Methods<br />
This survey was per<strong>for</strong>med as a web-based questionnaire linked to our hospital’s e-mail system sent to all surgeons,<br />
anaesthesiologists, theatre nurses and anaesthesia nurses who were employed at the COU February <strong>2009</strong>. Their<br />
experience with near-misses or mistakes, routines and views regarding the three check points and a “Time-out”<br />
protocol was registered.<br />
Results<br />
Feedback was received from 64% (427/275). Of these 38% had experience with unconfirmed patient identity,<br />
43% positioning on the wrong side, 80% unconfirmed anatomic site/side and 60% prepared <strong>for</strong> another procedure<br />
than planned. 50% of the responders regularly ensure patient identity, 61% regularly ensure operation site/<br />
side and 52% usually ensure the type of procedure. 91% responded positively to a “Time-out” protocol being<br />
implemented in our operating theatres.<br />
Conclusions<br />
This study confirmed that a majority of the surgical team had experiences related to near-misses or mistakes of<br />
concern <strong>for</strong> patient safety. Our present system does not give a sufficient opportunity <strong>for</strong> the surgical team to ensure<br />
the three most important check points be<strong>for</strong>e the incision. The study supports the implementation of a “Time-out”<br />
protocol in our operating theatres.<br />
S07:4<br />
OUT OF HOSPITAL(OOH) MANAGEMENT OF PATIENTS ON LVADS (LEFT VENTRICULAR ASSIST<br />
DEVICES). THE NORWEGIAN EXPERIENCE.<br />
Sorensen Gro 1 , Gude Einar 1 , Holter Marianne 1 , Fiane Arnt 1<br />
1) Rikshospitalet, Norway<br />
The purpose was to describe our program <strong>for</strong> OoH management and what we have learned about challenges, joys<br />
and worries.<br />
Background<br />
15 Ventrassist LVAD <strong>for</strong> heart failure has during the last three years been implanted at the University hospital of<br />
Oslo. 11 patients had LVAD as bridge to transplant and 4 as chronic therapy. The patients were aged 10-65 (mean<br />
38.9) years old. Duration on pump was 4 weeks-22 months. Six patients have been successfully transplanted, one<br />
patient recovered after 13 months, six patients are ongoing and two died early after implant.<br />
The patients had very different family support, social network and length of illness be<strong>for</strong>e implant.<br />
The challenges the patients meet also differ considerably. A training program is planned <strong>for</strong> each patient depending<br />
on their individual situation but will always be focused about how to handle the LVADsystem, how to manage<br />
common daily situations, emergency procedures, exitsite care and monitoring system parametres. In addition to<br />
that, the local hospital will be trained and also have an important role in follow up.<br />
Conclusion<br />
A variety of physical, mental and social issues influenze the ability of the LVAD patient to cope with daily life. Being<br />
confident is the foundation pillar, and it is our responsibility as a team with VAD-coordinators, doctors and nurses<br />
to help them building their own framework. A prospective study will be per<strong>for</strong>med to gain a better understanding of<br />
both patient and caregivers experience and what we as a VAD-team should focus on to optimize the support.<br />
54 www.sats<strong>2009</strong>.org
S07:5<br />
GENDER AND HEALTH-RELATED QUALITY OF LIFE AFTER CARDIAC SURGERY<br />
Gjeilo Kari Hanne 1 , Wahba Alexander 1 , Klepstad Pål 1 , Lydersen Stian 2 , Stenseth Roar 1<br />
1) St. Olavs Hospital, 2) NTNU, Trondheim, Norway<br />
Background<br />
Women undergoing cardiac surgery are older, have more comorbidities and are more functionally impaired than men<br />
be<strong>for</strong>e surgery. It has been argued that gender differences regarding outcome tend to reflect differences that exist<br />
preoperatively rather than differences related to cardiac surgery itself. In addition a slower rate of physical recovery<br />
has been shown in female patients. However, the literature is not consistent regarding gender differences in healthrelated<br />
quality of life (HRQOL) outcomes after cardiac surgery.<br />
Design and methods<br />
A prospective study was designed to assess HRQOL in patients undergoing cardiac surgery with emphasis on<br />
gender differences. Between September 2004 and September 2005, 534 patients (413 males and 121 females)<br />
were consecutively included. HRQOL was measured by the Short-Form 36 (SF-36) be<strong>for</strong>e surgery with follow-up<br />
6 and 12 months after surgery.<br />
Results<br />
521 patients were alive after 12 months, 462 (89 %) and 465 (89.4%) responded after 6 and 12 months respectively.<br />
Female patients had less favorable scores than male patients on most subscales of the SF-36 both be<strong>for</strong>e and<br />
after surgery. Both male and female patients improved substantially after surgery, but female patients reported<br />
significantly less improvement on 2 of 8 subscales of the SF-36; role emotional and bodily pain.<br />
Conclusions<br />
The study demonstrates that there are gender differences concerning HRQOL both be<strong>for</strong>e and after cardiac surgery.<br />
However, a clear overall improvement in HRQOL over the first year after cardiac surgery, more specifically during<br />
the first 6 months <strong>for</strong> both genders was found.<br />
S07:6<br />
QUALITY OF LIFE IN PATIENTS AND HIS RELATIVES UNDERGOING PERCUTANEOUS PULMONARY<br />
VALVE IMPLANT<br />
Andresen Brith 1 , Døhlen Gaute 1 , Mathisen Lars 1 , Andersen Marit 1 , Lindberg Harald 1 , Fosse Erik 1<br />
1) Rikshospitalet, Norway<br />
Background<br />
The total number of patients with congenital heart disease is increasing. Many of these patients need repeatedly<br />
open heart surgery. Percutaneous pulmonary valve implant may reduce the total number of surgical events.<br />
Aim<br />
To examine the patients and their familys experience of postoperative convalescence and return to daily activity after<br />
treatment. This study is a pilot to a comparative clinical study where two different treatment techniques are used.<br />
Methods: Patients and relatives were included in a cohort study and underwent both a semi structured interwiew<br />
and a specially designed questionnaire (T.M.Achenbach, 2001).<br />
Preliminary results<br />
Eight patients median age 17 have been treated with PPVI at University Hospital of Oslo. The patients stayed<br />
median 3 days in hospital. Five of the patients and their family returned to daily activity from one to six days after<br />
the event. Three of the patients emphasized less pain as a positive issue. It was confirmed by five parents that the<br />
short hospital stay had a positive influence both on their family situation and their job relations. Less absence from<br />
work was emphasized as a positive socio-economic factor among parents. Seven of the patients had started one<br />
or two physical activities three months after the intervention. Improved school achievement and better ability in<br />
concentration was stated by 5 of the parents, six mentioned improved socialization with friends.<br />
Conclusion<br />
This novel technique seems to offer lesser impact regarding pain and everyday life to both patient and their closest<br />
relatives. It may have a sosioeconomic advantage.<br />
STOCKHOLM, SWEDEN 55
S07:7<br />
ADDRESSING THE SPOUSES UNIQUE NEEDS AFTER CARDIAC SURGERY WHEN RECOVERY IS<br />
COMPLICATED BY HEART FAILURE<br />
Ågren Susanna 1 , Strömberg Anna 2 , Svedjeholm Rolf 3 , Berg Sören 4 , Hollman Frisman Gunilla 1<br />
1) Anesthesia and Intensive Care, 2) European Society of Cardiology,<br />
3) Cardiothoracic Surgery, 4) Cardiothoracic Anesthesiology Intensive, Sweden<br />
Background<br />
Cardiac surgery places extensive stress on spouses who often are more worried than the patients themselves.<br />
Spouses can experience difficult and demanding situations when the partner becomes critically ill.<br />
Objectives<br />
To identify, describe, and conceptualize the individual needs of spouses of patients with complications of heart failure<br />
after cardiac surgery.<br />
Methods<br />
Grounded theory using a mix of systematic coding, data analysis, and theoretical sampling was per<strong>for</strong>med. Spouses,<br />
10 women and 3 men between 39 and 85 years, were interviewed.<br />
Results<br />
During analysis, the core category of confirmation was identified as describing the individual needs of the<br />
spouses. The core category theoretically binds together three underlying subcategories: security, rest <strong>for</strong> mind<br />
and body, and inner strength. Confirmation facilitated acceptance and improvement of mental and physical<br />
health among spouses.<br />
Conclusions<br />
By identifying spouses’ needs <strong>for</strong> security, rest <strong>for</strong> mind and body, and inner strength, health care professionals can<br />
confirm these needs throughout the caring process, from the critical care period and throughout rehabilitation at<br />
home. Interventions to confirm spouses’ needs are important because they are vital to the patients’ recovery.<br />
S07:8<br />
PATIENT EDUCATION IN A REPRESENTATIVE SAMPLE OF PATIENTS HAVING ELECTIVE CARDIAC<br />
SURGERY IN ICELAND<br />
Olafsdottir Heida Steinunn 1 , Ingadottir Brynja 1 , Sveinsdottir Herdis 1 ,<br />
1) Landspitali University Hospital, Iceland<br />
Aim<br />
The aim of this study was to describe the perceived education and satisfaction with that education among patients<br />
undergoing elective cardiac surgery (CABG +/- AVR or AVR) at the Landspítali University Hospital in Iceland.<br />
Method<br />
This study used a descriptive, prospective correlational panel design. Data were collected with a questionnaire, at the<br />
hospital and at home six weeks later. Questions addressed patient education, symptoms, support and satisfaction<br />
with education, care and support as well as anxiety and depression that were measured with the Hospital Anxiety<br />
and Depression Scale. 111 patients who had surgery from January 15 until July 15, 2007, were invited to participate<br />
and 66 accepted.<br />
Findings<br />
The data analysis is not yet completed. The findings will describe the patients’ anxiety, symptoms, pain, perceived<br />
education and support and the correlation between those variables.<br />
Conclusion<br />
The preliminary findings indicate that the nursing care of cardiac surgery patients could be improved by identifying<br />
patients who are anxious per-operatively and provide them with individualised patient education at the hospital.<br />
Introducing post discharge follow-up is likely to increase patient satisfaction and recovery at home.<br />
56 www.sats<strong>2009</strong>.org
S09<br />
<strong>SATS</strong> CARDIOTHORACIC ORAL ABSTRACT SESSION<br />
S09:1<br />
OUTCOME AFTER PULMONARY METASTASECTOMY: ANALYSIS OF SURGICAL RESECTIONS<br />
DURING A 5 YEAR PERIOD.<br />
Hornbech Kåre 1 , Ravn Jesper B. 1 , Steinbrüchel Daniel A. 1<br />
1) Rigshospitalet, Denmark<br />
Objective<br />
Pulmonary metastasectomy <strong>for</strong> a wide range of different primary malignancies has become a progressively accepted<br />
treatment in patients with metastatic disease confined to the lungs. In the present single center study we analyze<br />
the results of management of pulmonary metastases in 5 years consecutive operations. We aim to define patients<br />
who are most likely to benefit from surgery by investigating long-term survival and prognostic factors associated<br />
with prolonged survival in a recent study population.<br />
Methods<br />
The data on all consecutive patients who underwent pulmonary metastasectomy between 2002 and 2006 were<br />
reviewed retrospectively. In total 178 patients underwent 256 surgical resections <strong>for</strong> suspected pulmonary metastases<br />
from different primary malignancies.<br />
Results<br />
Complete resection was achieved in 247 cases (96.4%). 25 patients (9.7%) had benign lesions and 25 patients<br />
(9.7%) had a primary lung cancer. 30-day morbidity and mortality were 6.6% and 1.9% respectively. Mean follow-up<br />
was 49.5 ± 17.8 months. The 5-year survival after metastasectomy according to primary tumour was: colorectal<br />
carcinoma 53.3%, sarcoma 20.9%, malignant melanoma 26.7%, renal cell carcinoma 38.1% and miscellaneous<br />
primary malignancies 50.0%. Of the prognostic factors analyzed by univariate analysis none were significant in all<br />
the different groups of cancers.<br />
Conclusions<br />
Pulmonary metastasectomy is a safe and effective treatment that leads to possible long-term survival in selected<br />
patients. Low morbidity and mortality rates in contrast with the lack of any other effective oncological treatment<br />
justify the aggressive approach of surgery. Solid prognostic factors need to be established.<br />
S09:2<br />
SURGICAL RESECTION OF PULMONARY METASTASES FROM COLORECTAL CARCINOMA IN ICELAND<br />
Vidarsdottir Halla 1 , Moller Pall 1 , Jonasson Jon Gunnlaugur 1 , Gudbjartsson Tomas 1<br />
1) Landspitali University Hospital, Iceland<br />
Background<br />
Over half of patients operated <strong>for</strong> colorectal cancer are later diagnosed with recurrent disease, most often<br />
metastases in the liver or lungs. Pulmonary metastases can be removed surgically; however, the survival benefit has<br />
been debated. The aim of this study was to study surgical outcome of pulmonary metastasectomy in a well defined<br />
patient cohort.<br />
Materials and methods<br />
All patients that underwent complete pulmonary resection of metastatic colorectal carcinoma from 1984-2008.<br />
Average follow up was 41 months.<br />
Results<br />
Altogether 32 procedures on 27 patients were per<strong>for</strong>med (age 63.5 yrs, range 35-80, 63% males). 19 with colon<br />
(70%) and 8 with rectal cancer (30%).The disease-free-interval was 29 months (range, 0-74) and 5 patients had<br />
undergone prior metastasectomy of the liver. Pre-thoracotomy CEA level was elevated in 9 of the patients. Eighteen<br />
patients had a solitary and 6 had two pulmonary nodules, other patients having multiple nodules. Lobectomy (n=18)<br />
and wedge resection (n=14) were the most common procedures. Three patients were operated <strong>for</strong> bilateral and 3<br />
<strong>for</strong> recurrent pulmonary metastases. All patients survived surgery and median length of hospital stay was 8 days<br />
(range, 5-58). Air leakage (19%) and pneumothorax (26%) were the most common complications. One and 5 year<br />
survival was 92.3 and 30.4%, respectively.<br />
Conclusion<br />
Surgical outcome in this series was good with low morbidity and mortality. The 5 year survival was 30.4 %, a much<br />
improved survival compared to patients with metastatic disease in general (
S09:3<br />
THE NO TOUCH VEIN GRAFT HARVESTING TECHNIQUE FOR CABG PRESERVES A FUNCTIONAL<br />
VASA VASORUM<br />
Dreifaldt Mats 1 , Souza Domingos 1 , Loesch Andrzej 2 , Muddle John 2 , Karlsson Mats 1 ,<br />
Norgren Lars 1 , Dashwood Michael 2<br />
1) Örebro University Hospital, Sweden, 2) Royal Free Hospital, United Kingdom<br />
Objectives<br />
To evaluate the impact of vein graft harvesting technique on structure and function of vasa vasorum.<br />
Methods<br />
Segments of great Saphenous veins harvested either with conventional harvesting technique (CT) or no<br />
touch technique (NT) were obtained from patients undergoing CABG. Quantitative measurements, using<br />
immunohistochemistry and morphometry, were per<strong>for</strong>med using a computerised imaging program. Ultrastructural<br />
analysis of vasa vasorum was per<strong>for</strong>med using electron microscopy. Sections of in vitro perfused vein grafts with<br />
infusion of ink into the perfusion line were analysed using light-microscopy. Video footage of flow in an incised vasa<br />
vasorum in an implanted saphenous vein graft harvested with the NT was captured during a CABG operation.<br />
Results<br />
The total area of vasa vasorum in vein grafts harvested with NT was significantly larger both in the media (p<br />
= 0.007) and in the adventitia (p = 0.014) compared to vein grafts harvested with CT. Ultrastructural findings<br />
indicated that NT preserved an intact vasa vasorum while CT did not. Perfusion of vein grafts in vitro showed filling<br />
of ink in vasa vasorum in grafts harvested with NT. Video footage showed retrograde flow in vasa vasorum in vein<br />
grafts harvested with NT.<br />
Conclusion<br />
These findings show that the NT <strong>for</strong> saphenous vein graft harvesting <strong>for</strong> CABG preserves an intact and functional<br />
vasa vasorum. This could represent one of the mechanisms underlying the improved patency <strong>for</strong> vein grafts harvested<br />
with this technique.<br />
S09:4<br />
IS THERE A PLACE FOR TOTAL ENDOSCOPIC ABLATION OF ATRIAL FIBRILLATION?<br />
Ahlsson Anders 1 , Fengsrud Espen 1 , Linde Peter 1 , Tydén Hans 1 , Englund Anders 4<br />
1) Örebro University Hospital, Sweden<br />
Study objective<br />
To evaluate the feasibility, efficacy and safety of total endoscopic ablation (TEA) of atrial fibrillation (AF) using<br />
microwave or radiofrequency energy.<br />
Method<br />
TEA was per<strong>for</strong>med using left single lung ventilation and CO2 insufflation in the right hemithorax. Through three<br />
right-sided working ports, an ablation catheter was positioned on the left atrial wall and a box lesion encircling all<br />
pulmonary veins was created (video demonstration).<br />
Results<br />
23 patients have undergone TEA since the start in May 2007. The indications were symptomatic AF in patients ><br />
50 years, and patients with a BMI > 35 were excluded. The median age was 67 yrs (52 – 83), and 5 patients were<br />
female. The frequency of paroxysmal/persistent/permanent AF were 9/5/9, respectively, and the median duration<br />
of AF 10 years.<br />
9 patients were ablated using a Flex X microwave catheter (Boston Scientific, USA) and 14 patients using a Cobra<br />
Adhere XL radiofrequency catheter (ESTECH, USA). There was no hospital mortality. One patient had a transient<br />
phrenical paralysis and one patient required a small thoracotomy to complete the ablation. The freedom of AF at<br />
follow-up was 7/10 patients (70%) after 12 months. Among radiofrequency ablated patients, the freedom of AF was<br />
9/9 patients after three months and 5/6 after 6 months.<br />
Conclusion<br />
TEA is a feasible method of AF ablation with preliminary acceptable results. The potential clinical role of TEA has to<br />
be further evaluated in prospective, randomised trials with careful monitoring of the AF burden during follow up.<br />
58 www.sats<strong>2009</strong>.org
S09:5<br />
STERNAL CLOSURE WITH THERMOREACTIVE CLIPS IN 1000 HIGH RISK PATIENTS<br />
- A SINGLE CENTRE COHORT STUDY.<br />
Balasubramanian Sendhil Kumaran 1 , Dunning Joel 1 , Avlonitis Vassilios 1 , Gill Michael 1 ,<br />
Goodwin Andrew 1 , Owens Andrew 1 , Kendall Simon 1<br />
1) The James Cook University Hospital, United Kingdom<br />
Background<br />
Nitillium thermoreactive clips are a novel method of sternalclosure. These clips are highly pliable at low temperature<br />
making them easy to place round the sternum but stiffen at body temperature. They also demonstrate elasticity<br />
on coughing, returning to their original position rather than cutting through. We sought to assess the incidence of<br />
sternal wound complications using these thermo-reactive clips(flexigrips) in 1,000 high-risk patients and identify the<br />
risk factors <strong>for</strong> deep sternal wound infection (DSWI).<br />
Methods<br />
From May-2004 to August-2008, 1,000 high-risk patients, had sternal closure using flexigrips. Perioperative and<br />
demographic variables were analyzed with univariate and multivariate logistic regression analysis to identify risk<br />
factors associated with DSWI.<br />
Results<br />
Median age was 64yrs and median BMI was 32. 85% were male, 30%diabetics and 75% had hypertension. 74% had<br />
CABG, 9% had valve replacements and 12% had combined procedures.There were no sternal complications in 981<br />
patients (98%). The total incidence of DSWI was 1.9% and sternal dehiscence was 1%. Superficial wound infection<br />
was 8.6%. Overall mortality was 1.6%. Multivariate analysis identified, BMI≥35 (Odds ratio 3.21:95%CI 1.16-8.85),<br />
type-II diabetes (Odds ratio 3.9:95%CI 1.27 – 12.3) and need <strong>for</strong> emergency resternotomy (Odds ratio 7.65:95%CI<br />
2.3-25.19) were significant risk factors <strong>for</strong> DSWI.<br />
Conclusions<br />
Thermo-reactive clips can be safely used <strong>for</strong> sternal closure in these high risk patients with an incidence of sternal<br />
dehiscence of 1%. Incidence of sternal dehiscence requiring surgery is low. BMI≥35, diabetes and mediastinal reexploration<br />
were additional predictors of DSWI.<br />
S09:6<br />
CARDIAC SURGERY IN PATIENTS WITH HAEMOPHILIA<br />
Tang Mariann 1 , Wierup Per 1 , Terp Kim 1 , Ingerslev Jørgen 2 , Sørensen Benny 2<br />
1) Department of Cardiothoracic Surgery, Aarhus University Hospital, Skejby,<br />
2) Center <strong>for</strong> Haemophilia and Thrombosis, Denmark<br />
Background<br />
Today the populations of haemophilia patients have a higher life expectancy than previously known, and age-related<br />
disorders are expected to become more prevalent. Cardiac surgery constitutes a major haemostatic challenge.<br />
Hence, only limited systematic in<strong>for</strong>mation exists on efficacious and safe haemostatic substitution regimens during<br />
and after these major surgical episodes. Furthermore, postoperative thromboprophylaxis with antiplatelet drugs is<br />
questionable and seem problematic in patients with haemophilia.<br />
Aim<br />
Evaluation of our current experience and results with cardiac surgery in patients with haemophilia. Provide detailed<br />
in<strong>for</strong>mation on the haemostatic treatment regimens adopted. Forward systematic details on the organization of<br />
haemostatic treatment regimens and postoperative thromboprophylaxis.<br />
Material & Methods<br />
Six patients with haemophilia A undergoing cardiac surgery. In<strong>for</strong>mation on concomitant disorders and EuroSCORE<br />
was registrated. Outcome measures were: (i)re-operation caused by bleeding, (ii) blood transfusion requirements,<br />
(iii) peri- and postoperative blood loss, (iv) peri- and postoperative complications and (v) postoperative development<br />
of inhibitors. Data was compared with historical data from patients without congenital haemophilia (n = 5977) as<br />
extracted from the Danish Heart Database.<br />
Results<br />
None of the six patients were reoperated due to bleeding and none developed inhibitors. Peri- and postoperative<br />
blood loss ranged from 565 to 1055 ml. No incidence of myocardial infarction or thromboembolic complications was<br />
seen. Data did not deviate from results with non-haemophiliacs undergoing major cardiac surgery. All patients were<br />
substituted with a recombinant factor VIII product.<br />
Conclusion<br />
Major cardiac surgery can safely be per<strong>for</strong>med in patients with congenital haemophilia. Outcome measures were<br />
acceptable in comparison with data from non-haemophiliacs.<br />
STOCKHOLM, SWEDEN 59
S09:7<br />
SURGICAL CORRECTION OF PECTUS EXCAVATUM AND CARINATUM - SIX YEARS OF EXPERIENCES<br />
AT KAROLINSKA UNIVERSITY HOSPITAL.<br />
Bergman Per 1<br />
1) Karolinska University Hospital, Sweden<br />
Objective<br />
The minimally invasive repair of pectus excavatum (p.e), the ”Nuss procedure” and the modified operation technique<br />
of pectus carinatum (p.c), the ”modified Ravitch procedure”, are becoming increasingly popular and has todaybecome<br />
well established and worldwide accepted.<br />
Methods<br />
Between 2004-<strong>2009</strong>, 76 patients in the county of Stockholm were operated at Karolinska (KS) and Clinica<br />
Vistahermosa (CV), Spain by the same surgeon. 46 cases with p.e were operated at KS and 10 cases were operated<br />
at CV. 8 cases with p.c were operated at KS and 12 cases at CV. 14 Pectus Bars (p.e) were also extracted at KS<br />
during this time.<br />
Results<br />
76 patients (68 men,8 women) with mean age of 17 years (range 12-34) were included. Mean time to discharge<br />
was 9 days (range 5-13) <strong>for</strong> Nussprocedure and 7 range (range 5-8) <strong>for</strong> modified Ravitch. Complications such as<br />
pain > 4 weeks occured in 6 patients (8%), intrapleural fluid in 1 patients (1%), small apical pneumothorax ocurred<br />
in 14 patients (25%) but had disappeared at the postop control 1 month later. Superficial infections localized in the<br />
incisions in 2 patients (3%). Deeper infection leading to removal of one stabilizator and one bar removal occured in<br />
2 patients (3%). Bars were removed after 3 years from 14 patients during this time.<br />
Conclusion<br />
These techniques have good outcome and few per/postoperative complications. The cosmetic results were very<br />
satisfying and the operations have very high Quality of Life appearence which also is going to be studied further.<br />
60 www.sats<strong>2009</strong>.org
S10<br />
<strong>SATS</strong> BASIC SCIENCE ORAL ABSTRACT SESSION<br />
S10:1<br />
INJECTION OF MESENCHYMAL STEM CELLS MODIFIED WITH VEGF GENE IN ISCHEMIC<br />
MYOCARDIUM IMPROVES CARDIAC FUNCTION IN RATS<br />
Hua Ping 1 , Yang Yanqi 2 , Chen Ju 1 , Peng Jiangzhou 1 , Chen Bosheng 1 , Han Jie 1 , Wang Youyu 1<br />
1) The 2nd hospital Sun Yat-Sen University, China, 2) University Hospital, Linköping, Sweden<br />
Objective<br />
To observe effect of implantation of mesenchymal stem cells (MSCs) transfected by vascular endothelial growth<br />
factor (VEGF) on myocardium regeneration and angiogenesis in ischemic region, and consequent cardiac function in<br />
rats with acute myocardial infarction (AMI).<br />
Methods<br />
MSCs of Sprague Dawley rat were isolated, cultured, and labeled then with bromodeoxyuridine (BrdU). Some<br />
of them were transfected by adenovirus vector encoding VEGF (Ad.VEGF) gene. AMI was created by ligation of<br />
LAD artery in 40 rats. Four weeks after the ligation, left ventricle ejections fraction (LVEF) was measured with<br />
echocardiography. The rats were divided into four groups with 10 rats in each. Group I: implantation of MSCs<br />
transfected by Ad.VEGF; Group II: implantation of MSCs; Group III: injection of Ad.VEGF; and Group IV: untreated.<br />
Four weeks thereafter, myocardium regeneration and angiogenesis were evaluated with immunohistochemistry.<br />
LVEF measurement was repeated.<br />
Results<br />
MSCs labeled with BrdU were found in the ischemic region in group I and II with incorporation into capillaries, and<br />
stained by TnT antibody. The capillary density of 14.4±1.3/high power field (HPF) in group I and 13.6±1.1/HPF<br />
in group III were significantly higher than that of 5.9±1.7/HPF in group II and 0.00/HPF in group IV (P
S10:3<br />
VALIDATION OF CYSTATIN C WITH IOHEXOL CLEARANCE IN CARDIAC SURGERY.<br />
Brondén Björn 1 , Eyjolfsson Atli 1 , Blomquist Sten 1 , Jönsson Henrik 1<br />
1) Heart and Lung Division, USiL, Sweden<br />
Introduction<br />
Postoperative renal dysfunction after cardiac surgery is not uncommon. Plasma creatinine is the most commonly used<br />
biomarker of glomerular filtration rate (GFR). Serum cystatin C is a more sensitive biomarker of GFR than plasma<br />
creatinine, but has not been validated in cardiac surgery. Iohexol clearance is a reference method <strong>for</strong> determination<br />
of GFR. The aim of this study is to validate cystatin C with iohexol clearance in cardiac surgery.<br />
Method<br />
Twenty-one patients scheduled <strong>for</strong> elective coronary artery bypass grafting (CABG) where prospectively enrolled<br />
in the study. Be<strong>for</strong>e surgery and on the second postoperative day an iohexol clearance was per<strong>for</strong>med. Cystatin<br />
C, creatinine, creatinine clearance and C-reactive protein (CRP) were determined be<strong>for</strong>e surgery and on the first,<br />
second, third and fifth postoperative day.<br />
Results<br />
A strong correlation between iohexol clearance and cystatin C was found both pre- and postoperatively (r = -0.80 and<br />
r = -0.89 respectively) and was stronger than the corresponding correlation <strong>for</strong> creatinine and creatinine clearance.<br />
A significant elevation of cystatin C concentrations was found on the second and third postoperative day, which was<br />
not seen in creatinine concentrations. No correlation was found between CRP, iohexol clearance and cystatin C.<br />
Conclusion<br />
This study validates cystatin C as a marker of glomerular filtration in cardiac surgery. The study did not indicate that<br />
the cystatin C levels were affected as a consequence of the inflammatory response. The study contributes to the<br />
assumption that cystatin C is superior to creatinine in detecting early decline in renal function in cardiac surgery.<br />
S10:4<br />
PLATELET REACTIVITY DURING CARDIOPULMONARY BYPASS (CPB) - CHANGES RELATED TO<br />
POSTOPERATIVE BLEEDING<br />
Ehnsiö Gustaf 1 , Norderfeldt Joakim 1 , Berg Sören 1 , Alfredsson Joakim 1<br />
1) Heart Centre,Linköping, Sweden<br />
Introduction<br />
The use of CPB during CABG surgery is associated with platelet dysfunction and consumption, contributing to<br />
perioperative bleeding. Our aim was to evaluate if platelet activity correlated to blood loss.<br />
Methods<br />
Platelet function in 30 patients undergoing CABG was analyzed using whole blood impedance aggregometry<br />
(Multiplate®) with ADP (adenosin diphosphate), TRAP (thrombin receptor activating peptide), AA (arachidonic<br />
acid) and COL (collagen) as activators. Platelet reactivity and platelet count was analyzed on multiple occasions<br />
perioperatively up to 18h postoperatively.<br />
Results<br />
Platelet reactivity to ADP and TRAP was significantly reduced at 30 minutes of CPB (p
S10:5<br />
THE HUMAN HEART RELEASES CARDIOTROPHIN-1AFTER CORONARY ARTERY BYPASS GRAFTING<br />
WITH CARDIOPULMONARY BYPASS<br />
Tian Yikui 1 , Ruan Xinhua 1 , Laurikka Jari 2 , Laine Seppo 2 , Tarkka Matti 2 , Wei Minxin 1<br />
1) China 2) Finland<br />
Objectives<br />
Cardiotrophin-1 is closely linked to many cardiovascular diseases, such as myocardial infarction and heart failure,<br />
and exhibits cardioprotective effect in ischemia-reperfusion injury. The present study was designed to investigate<br />
the course of CT-1 in patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass<br />
(CPB), and to evaluate the relationship between plasma CT-1 levels and postoperative cardiac function.<br />
Methods<br />
Twenty-four patients undergoing elective CABG were studied. Radial artery blood samples were collected be<strong>for</strong>e<br />
CPB, 5 and 20 min after reperfusion, and 1, 6, 12 and 24 h after CPB. Coronary sinus blood samples were<br />
collected be<strong>for</strong>e CPB, 5 and 20 min after reperfusion. Plasma CT-1 levels were measured using the ELISA method.<br />
Hemodynamic data were collected.<br />
Results<br />
Peripheral CT-1 levels did not change significantly postoperatively. Trans-myocardial CT-1 levels increased significantly<br />
5 and 20 minutes after reperfusion as compared to baseline. A weak positive correlation (r=0.408, p=0.048) was<br />
found between trans-myocardial CT-1 levels at 20 min after reperfusion and CI at 12 hours after CPB.<br />
Conclusions<br />
The heart secretes CT-1 after ischemic injury. Endogenous CT-1 might be cardioprotective to ischemia-reperfusion<br />
injury in patients undergoing CABG, but the precise mechanism of this effect warrants further research.<br />
S10:6<br />
ACUTE KIDNEY INJURY FOLLOWING CORONARY ARTERY BYPASS SURGERY USING THE RIFLE CRITERIA<br />
Helgadottir Solveig 1 , Indridason Olafur 2 , Sigurdsson Gisli 2 , Sigurjonsson Hannes 2 ,<br />
Arnorsson Thorarinn 2 , Gudbjartsson Tomas 2<br />
1) University of Iceland, 2) Landspitali University Hospital, Iceland<br />
Introduction<br />
Different rates of acute kidney injury (AKI) have been reported following open-heart surgery, ranging from 2 to 30%.<br />
This can be explained by variable study populations and a lack of consensus on AKI-criteria. Using international<br />
criteria we studied the incidence of AKI following CABG.<br />
Material and methods<br />
A retrospective study of all patients that underwent CABG in Iceland, in 2002-2006. Concomitant CABG procedures,<br />
e.g. as part of valve procedures, were excluded. AKI was defined according to the RIFLE criteria, using pre- and<br />
post-op creatinine levels.<br />
Results<br />
Of 569 patients, 97 (17%) had reduced estimated glomerular filtration rate (eGFR200 μmol/L. The mean pre- and post-op creatinine level of the<br />
total study population was 92 and 104 μmol/L, respectively (p=0.0001). Ninety patients (15.8%) experienced AKI;<br />
58 fell into RISK, 16 in INJURY and 16 in FAILURE categories. Patients with AKI were 4.1 yrs older (p=0.0001) and<br />
had lower pre-op eGFR (72 vs. 80 mL/min/1.73m2, p=0.009). Female gender (28% vs. 16%, p=0.01), hypertension<br />
(74% vs. 59%, p=0.01) and acute surgery (11% vs. 2%, p
S18<br />
PHYSIOTHERAPISTS ORAL ABSTRACT SESSION<br />
S18:1<br />
PRECAUTIONS AFTER MIDLINE STERNOTOMY. ARE THEY NECESSARY?<br />
Brocki Barbara Cristina 1 , Thorup Charlotte Brun 1 , Skindbjerg Hanne 1 , Svalgaard Marianne 1 , Andreasen Jan Jesper 1<br />
1) Aarhus Univers. Hosp, Denmark<br />
Background<br />
Patients after midline sternotomy are instructed on activity precautions to avoid sternal wound complications. We<br />
question how restrictive those precautions must be, since they can lead to a decrease in quality of life in the<br />
postoperative period.<br />
Aims<br />
To identify mechanical stress factors causing sternal instability and infection in order to draw up evidence based<br />
guidelines <strong>for</strong> activity after sternotomy.<br />
Methods<br />
Literature review (CINAHL, Pub Med, Cochrane Library and PEDRO) and crosschecking references.<br />
Results<br />
Mechanical stress factors acting upon the sternum and the overlying skin are: constant coughing, BMI ≥ 35, skin<br />
stress due to macromastia, excessive bilateral arm movements leading to skin breakdown, and loaded activity with<br />
long lever arm. Our recommendations <strong>for</strong> precautions after midline sternotomy are: avoid stretching both arms<br />
backwards at the same time <strong>for</strong> 10 days; use leg rolling with counterweighting when getting in and out of bed; only<br />
move arms within pain free range; protect sternum when coughing by crossing the arms in a “self hugging” posture;<br />
use supportive sternal vest when coughing constantly or when BMI ≥ 35, use supportive bra when breast cup ≥D;<br />
loaded activity should be done with the elbows close to the body <strong>for</strong> 6 to 8 weeks.<br />
Conclusion<br />
Cough is considered the most important single mechanical stress factor causing instability. We found no evidence to<br />
support weight limitation regarding activity, as long as the upper arms are kept close to the body, and activity within<br />
pain free range.<br />
S18:2<br />
A RANDOMIZED CONTROLLED TRIAL ON DEEP BREATHING EXERCISES WITH POSITIVE<br />
EXPIRATORY PRESSURE AFTER CARDIAC SURGERY<br />
Urell Charlotte 1 , Emtner Margareta 1 , Breidenskog Marie 1 , Westerdahl Elisabeth 1<br />
1) Physiotherapy, Uppsala University Hospital, Sweden<br />
Objectives<br />
Deep breathing exercises with positive expiratory pressure (PEP) has been shown to be beneficial on oxygenation<br />
after cardiac surgery, but there is no consensus about the optimal duration and frequency of the treatment. The<br />
aim of this study was to investigate the oxygenation effect of deep breathing exercises with PEP, with two different<br />
breathing rates, the first two days after cardiac surgery.<br />
Methods<br />
In a prospective, randomized study 131 patients over 18 years, who underwent cardiac surgery were randomized<br />
in two groups: treatment group (TG) (n=63), 10 deep breaths x 3 in a PEP-device every hour awake the first two<br />
postoperative days and control group (CG) (n=68) 10 deep breaths x 1 every hour awake the first two postoperative<br />
days. The main outcome measures were arterial blood gases. Tests were per<strong>for</strong>med the second postoperative day.<br />
Result<br />
Mean age was 68.5 years and 25% were women. TG had significantly higher arterial oxygen tension (PaO2 8.9 ±<br />
1.7 kPa vs 8.1 ± 1.4 kPa p= 0.004) and arterial oxygen saturation (SaO2 92.7 ± 3.7 % vs 91.1 ± 3.8%, p= 0.016)<br />
compared to the CG. Both groups had the same compliance to the breathing exercises.<br />
Conclusion<br />
A higher breathing rate resulted in an improved oxygenation and the groups had the same compliance to the exercises.<br />
There<strong>for</strong>e a higher breathing rate should be recommended the two first postoperative days after cardiac surgery.<br />
64 www.sats<strong>2009</strong>.org
S18:3<br />
PHYSICAL ACTIVITY ON PRESCRIPTION (FAR®)-A LONG TERM FOLLOW-UP OF FAR® PRESCRIBED<br />
AT A UNIVERSITY HOSPITAL<br />
Wennman Susanna 1 , Ståhle Agneta 2 ,<br />
1) Karolinska University Hospital, 2) Karolinska Institutet, Dep. NVS, Sweden<br />
Background<br />
The use of FaR® to patients with high risk <strong>for</strong> lifestyle related diseases and as a treatment <strong>for</strong> different diseases has<br />
increased recently. The effects on FaR® have mostly been studied in primary health care settings. There is a lack<br />
of data regarding long-term effects.<br />
Objective<br />
To evaluate long-term effects of prescribing FaR®.<br />
Method<br />
The patients (n=34) who received FaR® after a physiotherapeutic intervention at Karolinska University Hospital,<br />
Solna, and participated at the follow-up twelve months later answered standardized questions regarding adherence,<br />
self-reported physical activity and health.<br />
Result<br />
The most frequent diagnosis <strong>for</strong> patients receiving FaR were cardiovascular, pulmonary or kidney diseases. A<br />
majority of the patients (65%) were physically active as prescribed or active in other activities. The remaining<br />
patients had a lower self-reported physical activity level and health. An increased physical activity level was<br />
measured among those who adhered to the prescription (p=0.05). There was no significant difference in selfreported<br />
health among those patients who adhered to the prescription and those who did not.<br />
Conclusion<br />
To prescribe FaR® is an effective method to positively influence self-reported physical activity level and the<br />
adherence to the prescription is very good.<br />
Key-words: counseling, life style, physical therapy, primary prevention, public health<br />
STOCKHOLM, SWEDEN 65
P01<br />
POSTER SESSION<br />
P01:01<br />
PLATELET IMPEDANCE AGGREGOMETRY AND POSTOPERATIVE BLOOD LOSS AFTER CORONARY<br />
ARTERY BYPASS SURGERY<br />
Roman-Emanuel Christine 1 , Thimour-bergström Linda 1 , Önsten Linda 1 , Rexius Helena 1 , Jeppsson Anders 1<br />
1) Sahlgrenska University Hospital, Sweden<br />
Objective<br />
Platelet dysfunction may contribute to increased bleeding after cardiac surgery but is difficult to assess. Impedance<br />
whole blood aggregometry is a new point-of-care method to evaluate platelet function. We investigated in an ongoing<br />
study if there is any correlation between impedance aggregometry, and bleeding and transfusions after<br />
coronary artery bypass grafting (CABG).<br />
Methods<br />
Fifty-five consecutive CABG patients (men age 67+-9 years, 13% women) were included in a prospective observational<br />
study. 52/55 patients were treated with aspirin and 26 were also treated with the ADP receptor blocker clopidogrel<br />
within seven days be<strong>for</strong>e surgery. Platelet impedance aggregometry (Multiplate®) with adenosine-diphosphate<br />
(ADP) and thrombin receptor activated peptide 6 (TRAP) as activators, was per<strong>for</strong>med after induction of anesthesia<br />
and at sternum closure. Correlation between platelet aggregometry and postoperative bleeding was calculatedwith<br />
Spearman’s Rank sum test and platelet aggregometry variables were compared between transfused and nontransfused<br />
patients with student’s T-test.<br />
Results<br />
Mean postoperative blood loss was 561+-308 ml/12h and 20/55 patients (36%) were transfused with blood<br />
products. There was no significant correlation, neither between pre- and post-operative ADP-induced platelet<br />
aggregation and postoperative blood loss (r=-0.22, p=0.10 and r=–0.06, p=0.66,respectively) nor between pre-<br />
and post-operative TRAP-induced platelet aggregation and postoperative blood loss (r=0.06, p=0.68 and r=0.11,<br />
p=0.41). Furthermore, there were no significant differences in pre- and post-operative aggregometry variables<br />
between transfused and non-transfused patients.<br />
Conclusions<br />
Platelet function, as measured with impedance aggregometry with ADP and TRAP as activators do not correlate to<br />
postoperative bleeding and transfusion requirements after CABG.<br />
66 www.sats<strong>2009</strong>.org
P01:02<br />
A COMPARISON OF ANTICOAGULANTS IN WHOLE BLOOD PLATELET IMPEDANCE AGGREGOMETRY<br />
IN CABG PATIENTS<br />
Thimour-Bergström Linda 1 , Roman-Emanuel Christine 1 , Jeppsson Anders 1<br />
1) Sahlgrenska University hospital, Sweden<br />
Objective<br />
Impedance aggregometry is a new method to evaluate platelet function. Blood samples are collected in test tubes<br />
with anticoagulants and analyzed in a point-of-care device. We investigated if blood samples from CABG patients<br />
collected in tubes with hirudin and citrate gives comparable results.<br />
Methods<br />
Twenty CABG patients (mean age 66 +10 years) were included in a prospective observational study. 19/20 patients<br />
were treated with aspirin and 10 were also treated with the ADP receptor blocker clopidogrel within seven days<br />
be<strong>for</strong>e surgery. Platelet impedance aggregation (Multiplate®), with adenosine-diphosphate (ADP) and thrombin<br />
receptor activated peptide 6 (TRAP) as activators, was measured after induction of anesthesia and at sternum<br />
closure. Aggregation was expressed as area under the curve. Absolute difference, relative difference and correlation<br />
coefficients (r) were calculated.<br />
Results<br />
In ADP-induced aggregation was the absolute difference between hirudin and citrate tubes -7±11 units (13±12 vs<br />
5±4 units) and the relative difference -27±78%. There was no significant correlation between hirudin and citrate<br />
tubes aggregation (r=0.25, p=0.11). In contrast, there was a strong correlation between hirudin and citrate tubes in<br />
TRAP induced aggregation (r=0.84, p
P01:04<br />
RIGHT VENTRICULAR 3-D ARCHITECTURE IS PRESERVED DURING EXPERIMENTALLY INDUCED<br />
RIGHT VENTRICULAR HYPERTROPHY<br />
Nielsen Eva 1 , Smerup Morten 1 , Agger Peter 1 , Frandsen Jesper 1 , Lunkenheimer Paul P. 2 ,<br />
Anderson Rober H. 3 , Hjortdal Vibeke 1 ,<br />
1) Aarhus University Hospital, Skejby, Denmark, 2) University Münster, Germany,<br />
3) University Collage, London, United Kingdom<br />
Introduction<br />
The three-dimensional architecture of the myocytes in the right ventricular (RV) myocardium is a major determinant<br />
of function, but as yet no investigator-independent methods have been used to characterize either the normal<br />
or hypertrophied state. Our aim was to assess and compare, using diffusion tensor MRI (DTMRI), the normal<br />
architecture with the arrangement induced by chronic hypertrophy.<br />
Materials and methods<br />
20 female piglets were randomized into either pulmonary trunk banding or sham operations. RV hypertrophy was<br />
assessed by in vivo cardiovascular MRI after 8 weeks. Hereafter hearts were excised and fixated, and DTMRI was<br />
per<strong>for</strong>med to determine the helical angles of the myocytes aggregated within the walls, and the presence of any<br />
reproducible tracks <strong>for</strong>med by the aggregated myocytes.<br />
Results<br />
All banded animals developed significant RV hypertrophy, albeit no difference was observed in terms of helical<br />
angles or myocardial pathways between the banded animals and those undergone the sham operation. Helical<br />
angles varied from approximately 70º endocardially to -50º epicardially. Very few tracks were circular, with helical<br />
angles approximating zero. Reproducible patterns of chains of aggregated myocytes were observed in all hearts.<br />
Discussion<br />
The 3D-architecture of the RV is comparable to that found in the LV, although the RV lacks the extensive zone of<br />
circular myocytes found in the mid-portion of the LV walls. These circular tracks were also not observed in the RVs<br />
of banded animals. Without such beneficial architectural remodeling, the porcine RV seems unsuited structurally to<br />
sustain a permanent afterload increase.<br />
P01:05<br />
SURGERY FOR MYXOMA: A 10 YEAR EXPERIENCE<br />
Bondo Jørgensen Louise 1 , Steinbrüchel Daniel A. 1<br />
1) Rigshospitalet, Denmark<br />
Introduction<br />
Myxoma is a benign neoplasm that represents the most common primary tumor of the heart accounting <strong>for</strong> about<br />
50 % of all benign cardiac tumors. Despite its benign pathology this tumor may cause significant complication and<br />
mortality by affecting blood flow and causing arrhythmias and emboli.<br />
Material/Methods<br />
The records of 35 patients which underwent surgery <strong>for</strong> cardiac myxoma at Rigshospitalet, Copenhagen, identified<br />
during the period 1998 to 2008 were reviewed. Patients aged ranged from 23 to 90 years (median age 60); women<br />
predominated by a ratio of 1.2:1.<br />
In 29 patients the tumor was located in the “left side” of the heart (left ventricle/atrium), in 7 patients the myxoma<br />
was found in the right atrium/ventricle.<br />
Results<br />
In 8 patients the myxoma was found accidentally, 9 presented with emboli (cerebral or pulmonary), 18 patients were<br />
investigated du to cardiac symptoms. No significant differences with respect to age, gender, BMI or tumor pathology<br />
could be demonstrated in patients presenting with emboli compared to patients with cardiac symptoms. In 6 patients<br />
CABG , valve surgery or MAZE was per<strong>for</strong>med apart from myxoma resection. 30 day mortality was 2/35 (stroke/<br />
acute MI), 3 patients died during a median 4 year follow op.<br />
Conclusion<br />
Although cardiac myxoma is a benign disease, this tumor <strong>for</strong>m must be classified as potentially fatal due to a<br />
risk of embolisation. An embolic event was the initial clinical manifestation.in 25% of the patients. There<strong>for</strong>e an<br />
echocardiography should be considered in adults and young adults with cerebral or pulmonary embolism.<br />
68 www.sats<strong>2009</strong>.org
P01:06<br />
CARDIAC MYXOMA IN ICELAND - A NATION-WIDE CASE SERIES<br />
Sigurjonsson Hannes 1 , Andersen Karl 1 , Gardarsdottir Marianna 1 , Petursdottir Vigdis 1 , Klemenzson Gudmundur 1 ,<br />
Gunnarsson Gunnar Thor 1 , Gudbjartsson Tomas 1<br />
1) Landspitali University Hospital, Iceland<br />
Introduction<br />
Myxoma is the most common benign primary tumor of the heart, usually presenting with symptoms of systemic<br />
emboli or intracardiac obstruction. In recent years, incidental finding is also common. We studied all myxomas<br />
diagnosed in a well defined population during a 23 year period.<br />
Material and methods<br />
A retrospective population-based study including all patients diagnosed with cardiac myxoma in Iceland from 1986<br />
until March 1, <strong>2009</strong> (> 4300 operations per<strong>for</strong>med). Cases were identified through three different registries and<br />
databases.<br />
Results<br />
Nine cases were identified (3 males, 6 females) with mean age of 60.7 yrs (range 37-85). Age-adjusted incidence<br />
rate was 0.12 (95% CI: 0.05-0.22) per 100.000. Eight of the tumors were located in the left atrium and one in the<br />
right atrium. Average diameter was 4.4 cm (1.5-8.0). Dyspnea (n=5) and ischemic stroke (n=2) were the most<br />
common symptoms. Seven of the cases were diagnosed with transthoracal echocardiography and 2 with chest CT,<br />
one of them incidentally. All 9 patients underwent surgical resection, mean operation time being 238 min. All patients<br />
survived surgery and atrial fibrillation (n=5) was the most common complication. Median length of hospital stay was<br />
21 days and today (March 1, <strong>2009</strong>), 7 of the 9 patients are alive with no signs of recurrent disease.<br />
Conclusions<br />
Cardiac myxomas have similar incidence, presenting symptoms and mode of detection in Iceland as in other series.<br />
To our knowledge this is the first study reporting the incidence of cardiac myxoma in an entire population.<br />
P01:07<br />
TOPICAL NEGATIVE PRESSURE OVER CONVENTIONAL THERAPY OF DEEP STERNAL WOUND<br />
INFECTION IN CARDIAC SURGERY. PROSPECTIVE ANALYSIS.<br />
Simek Martin 1 , Hajek Roman 1 , Fluger Ivo 1 , Molitor Martin 1 , Langova Katerina 1 , Grulichova Jana 1 , Lonsky Vladimir 1<br />
1) University Hospital Olomouc, Czech Republic<br />
Introduction<br />
We sought to compare clinical outcomes, in-hospital mortality and 1-year survival of two different treatment<br />
modalities of deep sternal wound infection, topical negative pressure and the conventional therapy.<br />
Methods<br />
Prospective analysis of 66 consecutive patients treated <strong>for</strong> deep sternal infection at our institution. A total of 28<br />
patients (February 2002 through September 2004) underwent conventional treatment, and 34 patients (November<br />
2004 through December 2007) had the application of topical negative pressure. Four patients (July 2004 through<br />
December 2004) who underwent a combination of both strategies were excluded from the study. Clinical and wound<br />
care outcomes were compared, focusing on therapeutic failure rate, in-hospital stay and the 1-year mortality of both<br />
treatment strategies.<br />
Results<br />
Topical negative pressure was associated with a significantly lower failure rate of the primary therapy (p
P01:08<br />
THE EFFECT OF CO2-INSUFFLATION ON THE TEMPERATURE OF THE STERNOTOMY WOUND<br />
Frey Joana 1 , Svegby Henrik 2 , Svenarud Peter 1 , van der Linden Jan 1<br />
1) Karolinska University Hospital, 2) Royal Technical University, Sweden<br />
Background<br />
The open surgical wound is exposed to heat loss through radiation, evaporation and convection. Also, general<br />
anaesthesia contributes to a decrease in body temperature. Mild core hypothermia has been shown to contribute<br />
to cardiovascular morbidity, transfusion demands, delayed wound healing, postoperative wound infections, and<br />
extended hospitalization. A number of measures to prevent core hypothermia have been assessed as to their<br />
effectiveness but warming the open surgical wound by insufflating CO2 has so far not been investigated.<br />
Methods<br />
In 10 patients undergoing heart surgery, the surface temperature of an open cardiothoracic wound was measured<br />
with an infrared camera. Thermographic images were taken 2 minutes after opening of the pericardium, 2 minutes<br />
after insufflating the wound with dry room-tempered CO2 at a flow rate of 5 L/min via a gas diffuser, and 2 minutes<br />
after again exposing the wound to ambient air. Later off-analysis measured the average surface temperature of the<br />
whole wound.<br />
Results<br />
Exposure to CO2 increased the median temperature of the whole wound by 0.5°C (p=0.01) and the two thirds most<br />
distal to the diffuser by 1,2°C (p2 had been turned off. In the area closest to the diffuser the temperature decreased<br />
with 1.8°C (p2.<br />
Conclusion<br />
Short term insufflation of dry room-tempered CO2 in an open surgical wound cavity increases the surface temperature<br />
of the whole wound significantly. However, the temperature of the area closest to the diffuser decreased, most<br />
propably due to convection.<br />
P01:09<br />
THE PECTORALIS MUSCLE AXIAL FLAP WITH V-Y SKIN PADDLE FOR COVERING OF STERNAL DEFECTS.<br />
Molitor Martin 1 , Simek Martin 1 , Záleaák Bohumil 2 , Lonský Vladimir 1<br />
1) University Hospital Olomouc, Czech Republic<br />
Introduction<br />
Infectious wound complication after cardiovascular surgery is serious problem with high rate of associated morbidity<br />
and mortality and usually lead to wound dehiscence with sternal osteomyelitis and both bone and soft tissue defects.<br />
When infection is managed the reconstruction of the thoracic wall remains the main problem. Tissues used to<br />
cover the defect must be well nourished and suture must be absolutely tension free. We introduce our method of<br />
reconstruction using pectoralis muscle axial flap with V-Y skin paddle.<br />
Method<br />
Right pectoralis muscle is freed in the extent that allows its com<strong>for</strong>table shifting over whole sternal bone and V-Y<br />
skin paddle allows tension free skin suture in the midline.<br />
Results<br />
In the period of 2007-<strong>2009</strong> we have per<strong>for</strong>med four flaps. In two patients haematoma occured in the site of disconected<br />
humeral head of pectoralis muscle, in one patient in the proximal midline suture. In one patient peripheral necrosis<br />
of the distal part of the flap occured that needed resuturing and after that healed completely. All flaps survived and<br />
no dehiscence or other complication in the site of primary defect occured.<br />
Conclusion<br />
Our type of flap is reliable and easy to per<strong>for</strong>me. It has excellent blood supply and allow tension free suture of all<br />
tissues. Nosignificant superficial necrosis can occur in the most peripheral part of the flap. Its main disadvantage is<br />
that it cannot be used in female patients due to breast. Insignificant medial shifting of the areola in male patient is<br />
well tolerated.<br />
70 www.sats<strong>2009</strong>.org
P01:10<br />
CIRCULATORY ARREST AND BRAIN MONITORING<br />
Vainikka Tiina 1 , Wennervirta Johanna 1 , Ångerman-haasmaa Susanne 1 , Mäki Kaisa 1 , Vakkuri Anne 1 ,<br />
Sipponen Jorma 1 , Salminen Ulla-Stina 1<br />
1) Helsinki University Hospital, Finland<br />
Brain monitoring in patients undergoing aortic arch surgery is unreliable. During cardiopulmonary bypass, deep<br />
hypothermia and circulatory arrest, brain damage may occur at any time point.<br />
Prospective patient enrollment started 11/2007. Patients (30) undergoing cardiopulmonary bypass, deep hypothermia<br />
and circulatory arrest are included. CAD patients operated on-pump (15) or off-pump (15) serve as controls. For<br />
brain monitoring, continuous EEG recording and NIRS oximeter are used. Neuropsychological tests are done 6<br />
months postoperatively.<br />
So far 18 patients, F/M = 5/13, 55.6 + 13.8 years, EuroScore 19.3% + 20.0%, were enrolled. Diagnosis was<br />
ascending aortic dissection in 12 and rupture of ascending aortic aneurysm in 1. Elective surgery was per<strong>for</strong>med in<br />
additional 5. Circulatory arrest was 36.9 + 30.1 min. Both-sided (3) or right (5) selective cerebral perfusion was used<br />
in 8 <strong>for</strong> 38.4 + 26.6 min. 2 (6.7%) died intrahospitally, 6 (33.3%) had neurological complications; 3 severe cerebral<br />
infarctions. Neurological complications showed NIRS and/or EEG changes. So far 11 were controlled: 1 died, 2 were<br />
hospitalized <strong>for</strong> stroke, 8 were tested. All 6 not retired were working. 2 patients were intact, 5 showed mild cognitive<br />
changes, 1 was depressed. 10 on-pump controls, F/M = 1/9, 62.8 + 9.3 years, recovered uneventfully, 4 attended<br />
control: 2 were intact and 2 had mild cognitive changes. Of 3 off-pump controls, F/M=0/3, 61.3 + 15.8 years, 2<br />
attended and were intact.<br />
EEG and NIRS monitoring gives in<strong>for</strong>mation of the timing and severity of intra-operative brain damage. In less<br />
severe neurological complications 6-month results are good.<br />
P01:11<br />
NEGATIVE-PRESSURE WOUND THERAPY (NPWT) FOR STERNAL WOUND INFECTION<br />
“THE FIRST CASES IN ICELAND”<br />
Steingrímsson Steinn 1 , Gottfredsson Magnus 2 , Gudmundsdottir Ingibjorg 3 , Sjögren Johan 4 , Gudbjartsson Tomas 2<br />
1) 2) 3) University of Iceland, Landspitali University Hospital, Faculty of Nursing, Uni. of Iceland, Iceland<br />
4) Lund University Hospital, Sweden<br />
NPWT has been shown to be effective <strong>for</strong> treating sternal wound infections (SWI). Rather than leaving the wound<br />
open after debridement or use closed irrigation, a sponge is placed in the wound and negative pressure applied. This<br />
reduces bacterial load, increases blood flow and stimulates <strong>for</strong>mation of granulation tissue in the wound. The aim of<br />
this study was to evaluate the results of NPWT <strong>for</strong> SWI in Iceland.<br />
Consecutive case series, including all patients with SWI following cardiac surgery that required surgical revision,<br />
diagnosed between July 2005 and Dec 2008. During this period all patients with SWI were treated with NPWT.<br />
12 patients (age 69 yrs, 10 males, 9 following CABG) were identified (1,3% infection rate). Coagulase-negative<br />
staphylococci (n=6) and Staphylococcus aureus (n=4) were the most common pathogens. NPWT was initiated<br />
on the 19th day postoperatively (median, range 5-111) and the duration of treatment was 14 days (median, range<br />
5-36). In most cases (9/12) the sternal-wires were removed and the sponges replaced 2-8 times. Primary closure<br />
of the sternum was achieved following NPWT in 10 out of 12 cases. In one case of Pseudomonas aeruginosa<br />
infection, NPWT treatment failed and this patient was treated successfully with vinegar soaked gauzes. No major<br />
complications were directly related to NPWT, however one patient died of sepsis related to SWI. The other 11<br />
patients are alive today (Jan. <strong>2009</strong>) and without signs of infection.<br />
This small series shows promising results <strong>for</strong> NPWT of SWI in Iceland and that major complications are rare.<br />
STOCKHOLM, SWEDEN 71
P01:12<br />
REOPERATION FOR BLEEDING FOLLOWING OPEN HEART SURGERY IN ICELAND<br />
Smarason Njall 1 , Sigurjonsson Hannes 1 , Hreinsson Hreinsson 1 , Arnorsson Þorarinn 1 , Gudbjartsson Tomas 1<br />
1) Landspitali University Hospital, Iceland<br />
Introduction<br />
Postoperative bleeding is a potentially fatal complication following open heart surgery, with studies reporting a<br />
reoperation-rate <strong>for</strong> bleeding in the range of 2-6%. In Iceland surgical outcome after such reoperations has not been<br />
studied be<strong>for</strong>e.<br />
Material and methods<br />
This retrospective study included all adults that underwent open heart surgery in Iceland between 2000-2005, and<br />
were reoperated <strong>for</strong> bleeding.<br />
Results<br />
There were 103 reoperations (mean age 68 yrs, 76% males), out of 1295 open heart procedures per<strong>for</strong>med during<br />
the same period, giving a reoperation-rate of 8%. One third of the patients were taking aspirin and 8% clopidogrel<br />
less than 5 days be<strong>for</strong>e surgery. The bleeding in the primary operation averaged 1523 ml (range 300-4780) and<br />
3942 ml <strong>for</strong> the first 24 hours postoperatively. Every other patient was reoperated on within 2 h and 97% within<br />
24 hours. The patients received 16.5 units of packed cells, 15.6 units of plasma and 2.3 sets of thrombocytes. The<br />
most common postop complication was atrial fibrillation (58.3%), pleural effusion that needed drainage (24.3%),<br />
myocardial infarction (23.3%) and sternal wound infection (11.7%). Median length of stay was 14 days (range 6-85),<br />
including 2 days (range 1-38) in the ICU. Operative mortality was 15.5% and 1-year crude survival 79.6%.<br />
Conclusion<br />
Reoperation-rate of 8% is in the higher range compared to other studies. Bleeding is a serious complication, with<br />
high morbidity and significant mortality. Furthermore, cost is increased due to expensive transfusions and extended<br />
hospital stay. This emphasizes the necessity to find means to reduce post-operative bleeding.<br />
P01:13<br />
SURGICAL TREATMENT OF NEUROENDOCRINE BRONCHIAL TUMORS AT KAROLINSKA UNIVERSITY HOSPITAL<br />
Brodin Daniel 1 , Bergman Per 1 ,<br />
1) Karolinska University Hospital, Sweden<br />
Objective<br />
Due to the excellent prognosis of typical carcinoids (TC), parenchymal saving has been addressed <strong>for</strong> discussion<br />
as an alternative to anatomical resections. But many authors mean that there is not sufficient data to recommend<br />
parenchymal-saving (limited) operations in any carcinoids. The aim of the present study was to determine factors<br />
that could influence the long-time survival of patients treated surgically <strong>for</strong> neuroendocrine bronchial tumors and<br />
thereby help to establish criteria of limited operation.<br />
Methods<br />
The study was based on retrospective analysis of a total of 45 patients who were surgically treated <strong>for</strong> neuroendocrine<br />
bronchial tumours between 1987-2004. Cumulative survival was estimated by the Kaplan Meier method. Differences<br />
in survival were tested using log rank test.<br />
Results<br />
The 45 patients constituted 9 % of all operated and diagnosed lung tumours. Twenty-four were classified with TC,<br />
five with atypical carcinoids (AC), nine with small cell lung cancer (SCLC) and three with large cell lung cancer<br />
(LCNE). Four patients with carcinoids could not be further sub-classified. Overall 5-year survival rate was 73 %, <strong>for</strong><br />
TC 96 %, AC 60 %, SCLC 22 % and LCNE 33%. Smokers and men had a shorter survival compared to non-smokers<br />
and women. Patients with AC had a higher mean age (67.9) than patients with TC (57.6).<br />
Conclusion<br />
There is a favourable outcome <strong>for</strong> the TC and these patients could be considered <strong>for</strong> parenchymal-saving<br />
operations.<br />
72 www.sats<strong>2009</strong>.org
P01:14<br />
BILATERAL LUNG VOLUME REDUCTION SURGERY FOR SEVERE EMPHYSEMA<br />
Gunnarsson Sverrir I. 1 , Johannsson Kristinn B. 1 , Gudjonsdottir Marta 2 , Magnusson Björn 3 ,<br />
Beck Hans J. 2 , Gudbjartsson Tomas 1<br />
1) Landspitali University Hospital, 2) Reykjalundur Rehabilitation Center, 3) Neskaupstadur Hospital, Iceland<br />
Introduction<br />
Lung volume reduction surgery (LVRS) can be used as a palliative treatment <strong>for</strong> severe emphysema in appropriately<br />
selected patients. The aim of this study was to evaluate the results of LVRS in Iceland.<br />
Materials and methods<br />
A prospective study of 16 consecutive LVRS patients (age 59 yrs, 10 males) with severe emphysema operated<br />
between 1986 and 2008. Approximately 20% of each lung was excised through a sternotomy, using a linear<br />
stapler. All patients were extubated at the end of the procedure. Function tests were done pre- and 2-4 months<br />
postoperatively.<br />
Results<br />
Average operation time was 86 min. (range 55-135) and hospital stay 26 days (range 9-85). There were no<br />
postoperative deaths and prolonged airleak was the most common complication (n=7). Four patients needed<br />
reoperation; including 3 with sternal dehiscence and one with sternal wound infection. Preoperatively, FEV1 was 0.97<br />
L (33% of predicted) and TLC 7,8 L (132% of predicted), RV 4.5 L (205% of predicted) and exercise capacity 69 W.<br />
Postoperatively FEV1 had increased significantly by 34% to 1,3 L (p=0.004), but other changes were not significant.<br />
Today (April <strong>2009</strong>), 10 out of 16 patients are alive, with median crude survival of 96 months (range 9-151).<br />
Conclusion<br />
In this small series, FEV1 significantly improved after LVRS. All the patients survived surgery, however, complications<br />
were common and hospital stay extended. LVRS appears to benefit some patients with severe emphysema. However,<br />
due to small patient numbers our results have to be interpreted cautiously.<br />
P01:15<br />
SURGICAL RESECTIONS FOR GIANT PULMONARY BULLAE<br />
Gunnarsson Sverrir I. 1 , Johannsson Kristinn B. 1 , Asgeirsson Hilmir 1 , Gudjonsdottir Marta 2 ,<br />
Magnusson Bjorn 2 , Gudbjartsson Tomas 1<br />
1) Landspitali University Hospital, 2) Reykjalundur Rehabilitation Center, Iceland<br />
Background<br />
Giant bullae are large dilated air spaces, often occupying more than 1/3 of the hemithorax in patients with emphysema.<br />
The aim of this study was to evaluate the surgical outcome of resections <strong>for</strong> giant bullae in Iceland.<br />
Materials and methods<br />
A retrospective review of 12 consecutive patients (age 58 yrs, 11 males) with severe emphysema who underwent<br />
bullectomy (8 bilateral and 4 unilateral) in Iceland during 1992-2008. Except <strong>for</strong> one lobectomy per<strong>for</strong>med through a<br />
thoracotomy all patients were operated with wedge resection through sternotomy. In all cases pre- an postoperative<br />
lung function studies were per<strong>for</strong>med.<br />
Results<br />
Average operation time was 91 min (range 75-150). Preoperatively FEV1 was 1.0 L (33% of predicted) and FVC 2.9<br />
L (68% of predicted). Two months postop an 80% increase in FEV1 was noted (1.8 L, 58% of predicted, p=0.015)<br />
but only 7% increase in FVC (2.9 L, 68% of predicted, p=0.6). All patient survived surgery and the most common<br />
complications were prolonged air leak (>7 days) (n=9) and pneumonia (n=2). One patient was reoperated on <strong>for</strong><br />
sternal dehiscience. Median hospital stay was 36 days (range 10-74). Today (May <strong>2009</strong>) 7 patients are alive, but the<br />
other 5 patients died 9 yrs median after the operation (100% 5-year survival).<br />
Conclusion<br />
Results of bullectomy in this small series is good. There was a significant increase in FEV1, major complications were<br />
rare and long-term survival acceptable. Prolonged air leak is a common postoperative complication that prolongs<br />
hospital stay of these patients.<br />
STOCKHOLM, SWEDEN 73
P01:16<br />
PNEUMONECTOMY FOR NON-SMALL CELL LUNG CANCER IN ICELAND: EARLY COMPLICATIONS<br />
AND LONG TERM SURVIVAL<br />
Thorsteinsson Hunbogi 1 , Jonsson Steinn 2 , Alfredsson Hordur 3 , Isaksson Helgi 4 , Gudbjartsson Tomas 3<br />
1) 2) 3) Fac. of medicine, University of Iceland, Dpt. of pulmonology, Dpt. of cardiothoracic surgery,<br />
4) Dpt. of pathology, Iceland<br />
Objective<br />
Pneumonectomy is required <strong>for</strong> large or central non small cell lung cancer (NSCLC). This study aims to investigate<br />
the indications, complications and surgical outcome of pneumonectomy <strong>for</strong> NSCLC in Iceland.<br />
Material and methods<br />
A retrospective study of all pneumonectomies per<strong>for</strong>med <strong>for</strong> NSCLC in Iceland 1988-2007. Clinical in<strong>for</strong>mation was<br />
retreived from medical records and all cases staged using the TNM staging system. Survival and prognostic factors<br />
were evaluated using Cox multivariate analysis.<br />
Results<br />
77 patients (64% males) with mean age of 62.3 yrs. were operated on, 44% on the right side. Mediastinoscopy<br />
was per<strong>for</strong>med in 31% of cases. Most patients were stage I or II (58%), but 17% and 21% were stage III A and IIIB,<br />
respectively. Mean operating time was 161 min., bleeding 1,1 L and hospital stay 11 days. Atrial fibrillation/flutter<br />
(21%), pneumonia (6%), empyema (5%) and respiratory failure (5%) were the most common complications. Three<br />
(3.9%) patients died within 30 and 8 (10.4%) within 90 days of surgery. Five year survival was 21%. Age (HR 1.035),<br />
airway obstruction (HR 2.9), large cell- or adenocarcinoma histology (HR 2.21) and TNM stage IV vs. I (HR 16.5)<br />
were independent predictors of poor survival. Operation in the later 10 year period predicted improved survival (HR<br />
0.55, p= 0,03).<br />
Conclusions<br />
Pneumonectomies <strong>for</strong> NSCLC in Iceland have a low rate of complications and operative mortality. Long term survival,<br />
however, is lower than expected, possibly related to insufficient preoperative staging, with only 1 out of 3 patients<br />
undergoing mediastinoscopy prior to pneumonectomy.<br />
P01:17<br />
MEDIASTINOSCOPY – INDICATIONS AND EARLY COMPLICATIONS.<br />
Olafsdottir Thora Sif 1 , Gudmundsson Gunnar 2 , Björnsson Jóhannes 3 , Gudbjartsson Tomas 1 ,<br />
1) Department of surgery, 2) Department of pulmonary medicine, 3) Department of Pathology, Landspitali, Iceland<br />
Introduction<br />
Mediastinoscopy is an important tool <strong>for</strong> staging lung cancer and evaluating mediastinal pathology. The objective of<br />
this retrospective study was to investigate the indications and safety of mediastinoscopy in a well defined cohort of<br />
patients.<br />
Material and methods<br />
All patients that underwent mediastinoscopy in Iceland between 1983-2007 were included. Clinical in<strong>for</strong>mation was<br />
obtained from patient charts and pathology reports were reviewed. For comparison the study-period was divided<br />
into 5-year periods.<br />
Results<br />
282 operations were per<strong>for</strong>med but in 34 cases data was missing, leaving 248 patients <strong>for</strong> analysis (mean age 59<br />
yrs, range 11-89, 150 males). A steady increase was seen in the number of operations, or 16 compared to 85 during<br />
the first and last periods, respectively (p500 ml (0,8%). There were two operative deaths, one due to a major intraoperative bleeding from a<br />
mediastinal tumor that infiltrated the aortic arch and one from a post-operative pseudomonas pneumonia.<br />
Conclusions<br />
The number of mediastinoscopies is increasing in Iceland, especially as a part of lung cancer staging. Mediastinoscopy<br />
is a safe procedure with low mortality and morbidity.<br />
74 www.sats<strong>2009</strong>.org
P01:18<br />
THYMIC EPITHELIAL TUMORS: HISTOLOGY, STAGING AND THE RESULTS OF SURGICAL REMOVAL<br />
Mariusdottir Elin 1 , Gudbjartsson Tomas 2 , Sigfusson Nikulas 2<br />
1) University of the Iceland, 2) Landspitali University hospital, Iceland<br />
Objective<br />
Most thymic tumors are of epithelial origin with different clinical behavior and prognosis. Our aim was to study<br />
the histological subtype and tumor stage of thymic epithelial tumors in Iceland and evaluate the results of<br />
surgical treatment.<br />
Materials and methods<br />
16 consecutive patients (mean age 61 yrs, 10 males), diagnosed with thymic tumor in Iceland, from 1984 to <strong>2009</strong>,<br />
were studied retrospectively. The histological subtype was determined according to the new WHO classification<br />
(A-C) and the Masoka-system used <strong>for</strong> staging the tumors.<br />
Results<br />
Seven patients had local symptoms (chest pain, cough), seven were diagnosed incidentally and 2 were diagnosed<br />
during a work-up <strong>for</strong> myasthenia gravis. Benign tumours were 12, and thymic carcinomas four (25%). The histological<br />
subtype was type A (n= 4), type AB (n=2), type B1 (n=1), type B2 (n=5) and type C (n=4), with no B3 tumors.<br />
Majority of the tumors were on stage I (n=4) or II (n=5) but the carcinomas were two on each stage, III and IV.<br />
Twelve of the 16 patients underwent a radical resection of the tumor through a median sternotomy. There were no<br />
major complications and all the patients survived surgery. Overall crude survival <strong>for</strong> the 16 patients at 5 years was<br />
56%, 75% <strong>for</strong> thymomas and 0% <strong>for</strong> thymic carcinoma.<br />
Conclusions<br />
Tumors in the thymus are rare, most of them benign thymomas with excellent prognosis. For thymic carcinomas,<br />
however, the prognosis is poor and these patients usually die within one year from diagnosis.<br />
P01:19<br />
MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH SEVERE LEFT VENTRICULAR<br />
DYSFUNCTION, IS ON PUMP BEATING THE PREFERABLE TECHNIQUE?<br />
Abdel Aal Mohamed 1<br />
1) Riyadh, Saudi Arabia<br />
Objective<br />
This study compares early outcomes after on-pump beating-heart CABG and conventional CABG in patients with<br />
ejection fraction (EF) less than 30%.<br />
Methods<br />
From 2005 to 2008, 167 patients with ejection fraction less than 30% underwent CABG on-pump beating-heart<br />
CABG was done in 75 patients (group 1) and 95 patients were done using conventional technique (group2). Twelve<br />
patients in the conventional CABG group required insertion of intra-aortic balloon pump initiation intra-operatively<br />
or postoperatively, whereas only 2 patients required this in the on-pump beating-heart CABG group.<br />
Results<br />
In-hospital mortality was less in the on-pump beating-heart CABG group (2.25% versus 3.68). Twelve patients in the<br />
conventional CABG group required insertion of intra-aortic balloon pump initiation intra-operatively or postoperatively,<br />
whereas only 2 patients required this in the on-pump beating-heart CABG group.The ventilation time was longer<br />
in conventional group it was 10± 12.3 versus 7.6±11.7. No significant difference was found in morbidity including<br />
stroke, renal failure. The incidence of postoperative atrial fibrillation was significantly less in on pump beating group<br />
as compared to CPB group it was happened in 6 patients versus 21 respectively. The duration of intensive care unit<br />
stay was 2.9 ±1.65 in group 1 while it was 3.7± 1.78 group 2. The hospital stay was also shorter in the on-pump<br />
beating-heart CABG group, it was 6.8± 1.43 versus 8.6 ±2.13 and it was significantly difference.<br />
Conclusions<br />
On-pump beating-heart CABG can be per<strong>for</strong>med safely on high-risk patients.<br />
STOCKHOLM, SWEDEN 75
P01:20<br />
SURGICAL REVASCULARIZATION AFTER ACUTE MYOCARDIAL INFARCTION, IS IT RUNNING<br />
AGAINST THE CLOCK?<br />
Abdel Aal Mohamed 1<br />
1) Riyadh, Saudi Arabia<br />
Objective<br />
The optimal timing <strong>for</strong> surgical revascularization after acute myocardial infarction (MI) remains controversial. Higher<br />
mortality <strong>for</strong> emergency coronary artery bypass grafting (CABG) after acute myocardial infarction (AMI), ranging<br />
from 5% to 30%, has been documented since the early 1970.<br />
Patients and methods<br />
We examined our experience retrospectively in 278 patients who underwent CABG between 2005 and 2007 at<br />
king Fahad cardiac center in king khaled university hospital, Riyadh, Saudi Arabia. We had three groups one who<br />
underwent CABG within 24hours (group 1) , group 2 between 1 to 3 days and last group 3 after 14 days.<br />
Results<br />
The operative mortality associated with increasing time intervals between MI and CABG were 11.68%, 7.05%,<br />
2.5 %, <strong>for</strong> group 1(within 24 hours), group 2 and 3 respectively. In comparison, the incidence of cerebrovascular<br />
(CVA) and atrial fibrillation (AF) were greater in group 1 and the length of ICU stay was longer <strong>for</strong> patients<br />
undergoing CABG early after MI (within 24 hours). Emergency coronary artery bypass grafting (CABG) after<br />
AMI within 24 hours (group 1) has a significantly higher risk.<br />
Conclusion<br />
Nonemergency surgical revascularization can be done safely at any time interval after acute myocardial infarction,<br />
certainly after 72 hours, without increase in operative mortality and acceptable<br />
P01:21<br />
SURVIVAL BENEFIT OF CORONARY ENDARTERECTOMY IN PATIENTS UNDERGOING COMBINED<br />
VALVE AND CORONARY BYPASS GRAFTING<br />
Javangula Kalyana 1 , Papaspyros Sotoris 1 , Nair Unnikrishnan 1<br />
1) Leeds General Infirmary, United Kingdom<br />
Objectives<br />
Coronary Endarterectomy (CE) in patients undergoing coronary artery graft (CABG) surgery has been shown to<br />
be useful in re-vascularization of patients with diffuse disease. We present our experience with CE in patients<br />
undergoing valve surgery combined with coronary bypass.<br />
Methods<br />
Between 1989 and 2008, 237 patients underwent CABG with valve surgery under a single surgeon. Of these, 41<br />
patients had in addition CE. The data was retrospectively obtained from the notes and database. The follow-up<br />
was obtained by telephonic interview. All variables were analyzed by univariate analysis <strong>for</strong> significant factors <strong>for</strong><br />
in hospital mortality. Morbidity and long term survival was also studied. There were 29 males and 12 females with<br />
a mean age of 67.4 ±8.1 and body mass index of 26.3±3.3. Their mean euroscore was 7.6±3.2 and the log euro<br />
score was 12.2 ± 16.1.<br />
Results<br />
In hospital mortality was 9.8% (4 out of 41) with 6 late deaths. Long-term survival at 10 years was estimated to<br />
be 57.2% (95% CL 37.8%-86.6%). Average hospital stay was 12.7±10.43 days. ICU stay was < 48 hours in 32<br />
patients.The symptom relief was noted in majority with only 3 of the survivors having NYHA class II symptoms. One<br />
of the survivors was on nitrates and none required any further percutaneous or cardiac surgical intervention.<br />
Conclusions<br />
Coronary Endarterectomy does not increase mortality in combined procedures. By achieving more complete<br />
revascularization, it may be offering survival benefit in this group of patients. However this needs to be confirmed<br />
on studies with larger number of patients.<br />
76 www.sats<strong>2009</strong>.org
P01:22<br />
URGENT CABG PREDISPOSES PATIENTS TO REOPERATIONS- MAINLY DUE TO EXCESSIVE BLEEDING<br />
Suojaranta-ylinen Raili 1 , Hiippala Seppo 1<br />
1) Helsinki University Hospital, Finland<br />
Treatment of acute coronary syndrome (ACS) demands aggressive anti-thrombotic therapy and occasionally<br />
also mechanical circulatory support. Both may increase the risk of reoperation after urgent CABG surgery. This<br />
retrospective study was focused on the causes of these reoperations.<br />
Methods<br />
The inclusion criteria were urgent or emergent CABG after admission <strong>for</strong> ACS and the use of cardiopulmonary<br />
bypass. Combined operations including valves or other procedures and off-pump surgeries were excluded. 544<br />
patients were found with an estimated 95.7 % coverage of the target population. All patient records were reviewed<br />
to verify the cause of reoperation. The results were compared to a group of elective CABG patients. The odds ratios<br />
with 95% confidence intervals were calculated <strong>for</strong> the relevant events.<br />
Results<br />
The groups were comparable regarding sex, age, perfusion time, number of distal anastomosis and ReDo operations.<br />
The urgent group had significantly higher Euroscore, all patients were exposed to anti-thrombotic therapy and 12.5%<br />
had perioperative intra-aortic balloon pump compared to just 1.1% in the elective group. In the urgent group the<br />
odds were 2,83 (1,40-5,70) <strong>for</strong> a reoperation due to excessive bleeding and 4,11 (1,53-11,04) <strong>for</strong> all other causes<br />
compared to the elective group. The proportion of reoperations <strong>for</strong> surgical bleeding was the same in both groups.<br />
Conclusions<br />
Urgent CABG increased the odds <strong>for</strong> reoperation three to four fold and in two cases out of three the indication was<br />
excessive bleeding. In both groups the cause of bleeding was surgical in more than two reoperations out of three.<br />
P01:23<br />
OBESITY AND THE RATE OF EARLY COMPLICATIONS AFTER CORONARY ARTERIAL REVASCULARISATION<br />
Oddsson Saemundur J. 1 , Sigurjonsson Hannes 1 , Arnorsson Thorarinn 1 , Gudbjartsson Tomas 1<br />
1) Landspitali University Hospital, Iceland<br />
Introduction<br />
Traditionally obesity has been related to increased postoperative morbidity and mortality following open heart<br />
surgery. Recent studies, however, indicate that the association of obesity and complications is not straight-<strong>for</strong>ward,<br />
with some studies even reporting a beneficial association (obesity paradox). The aim of this study was to study this<br />
relationship in a well defined cohort of CABG/OPCAB patients.<br />
Material and methods<br />
A retrospective non-randomised study on all patients that underwent CABG/OPCAB in Iceland from June 2002<br />
to February 2005. There were 279 patients that were divided into two groups, an obese group (defined as BMI ><br />
30 kg/m2) (28%), and a non-obese group (BMI ≤30 kg/m2) (72%). Demographics, risk factors, complications and<br />
operative mortality (OM) of both groups were compared.<br />
Results<br />
Patient demographics were similar in both groups, including the rate of risk factors such as diabetes mellitus,<br />
hypertension and hyperlipidemia (Table 1). Type of surgery (CABG vs. OPCAB) was also comparable, however,<br />
EuroSCORE was significantly lower in the obese group and operation- and cross-clamp time longer. There were no<br />
significant differences in rates of either major or minor complications and the same was true <strong>for</strong> OM. Hospital stay,<br />
bleeding and transfusion requirements were also comparable between groups.<br />
Conclusion<br />
Obese patients seem to do as well as non-obese patients following coronary arterial revascularisation, at least<br />
regarding short-term complications and OM. Because obese patients had significantly lower EuroSCOREs, the<br />
effects of selection bias can´t be ruled out.<br />
STOCKHOLM, SWEDEN 77
P01:24<br />
HOW DOES INTRAOPERATIVE ASSESSMENT OF DISTAL LAD DISEASE TRANSLATE INTO<br />
CLINICAL OUTCOME?<br />
Svedjeholm Rolf 1 , Vanky Farkas 1<br />
1) Linköping University Hospital, Sweden<br />
Objective<br />
It is generally appreciated that the quality of coronary vessels are important <strong>for</strong> successful revascularization.<br />
Intraoperative assessment of coronary vessel quality by inspection, palpation and probing is routinely per<strong>for</strong>med. It<br />
is questionable to what extent an assessment subject to investigator bias translates into clinical outcome. As our<br />
institutional database contained in<strong>for</strong>mation about intraoperative assessment of quality of distal LAD we decided<br />
to investigate this issue.<br />
Method<br />
Data were registered prospectively in a computerized institutional database. 1751 patients had calcification of<br />
distal LAD classified by the surgeon as none, mild, moderate or severe. In 1034 patients it was classified as none<br />
or mild (Group NM) and in 234 patients it was classified as severe (Group S). These groups were compared with<br />
regard to outcome.<br />
Results<br />
Average age did not differ between Group S (65±1 years) and Group NM (66±1 years) but the proportion of<br />
patients with diabetes (28.2% v 15.3%; p
P01:26<br />
RETROTHYMIC ROUTING FOR SKELETONIZED INERNAL THORACIC ARTERIES:<br />
OPTIMAL LENGTHS, BEST COURSE, MAXIMAL PROTECTION<br />
Kargar Faranak 1 , Pooraliakbar Hamid-reza 1 , Yaghoubi Nahid 1 , Malek Hadi 1 , Aazami Mathias 1<br />
1) Shahed Rajaei Heart Hospital, Iran<br />
Introduction<br />
Routing in-situ internal thoracic arteries (ITAs) towards their coronary targets is a salient technical aspect. The latter<br />
should offer a smooth course providing maximal tension-free lengths, avoid technical flaws as graft kinking or errors<br />
in angulations of sequential anastomoses, decouple in-situ ITAs from respiratory mechanics, and offer protection by<br />
the time of re-sternotomy. In line with a<strong>for</strong>ementioned prerequisites, we report on a new technique <strong>for</strong> routing of the<br />
both right and left ITAs.<br />
Patients and methods<br />
Since 2007 to present, 158 patients (mean age 59.53±9.3 years; female: 25.6%; mean preoperative EF: 43 ±8.36 %;<br />
mean logestic euroscore: 5.75 ± 6.5) underwent CABG using one or both skeletonized ITAs. The ITAs were routed<br />
using the current technique in a retrothymic position towards LAD system, RCA or circumflex artery branches.<br />
Results<br />
158 left and 55 right in-situ ITAs were used. The mean number of grafts per patient was 2.9±0.8 (venous: 1.03±<br />
1.1; arterial 1.87±0.96). 90 % of LITA was used to feed LAD system and 74% of RITA was anastomosed to RCA<br />
branches. A composite arterial graft was per<strong>for</strong>med in 22% and 20% of patients needed concomitant coronary<br />
procedures. The overall hospital mortality was 1.8% and 3.6% of patients suffered perioperative MI mostly due to<br />
extensive concomitant endarterectomy. None of the patients suffered phrenic nerve dysfunction.<br />
Discussion<br />
Retrothymic routing <strong>for</strong> ITAs is a safe and reproducible method. Decoupling in-situ ITAs from respiratory mechanics,<br />
respecting the pleura, and avoiding splitting of the pericardium are some of its technical advantages.<br />
P01:27<br />
NUMBER OF CEREBRAL EMBOLI IS RELATED TO ACCESS SITE AT CORONARY ANGIOGRAPHY<br />
Nyman Jesper 1 , Jurga Juliane 1 , Sarkar Nondita 1 , Tornvall Per 1 , Manilla Maria N. 1 ,<br />
Svenarud Peter 1 , van der Linden Jan 1<br />
1) Karolinska Institute, Sweden<br />
Background<br />
Stroke is a severe but unusual complication during coronary angiography (CA). Recent studies have shown that<br />
particulate cerebral emboli are common during CA, but their role in this context is not entirely understood. The choice<br />
of access site <strong>for</strong> CA might be of importance. The aim of this study was to evaluate if the number of particulate<br />
cerebral emboli when a radial is compared with a femoral access site during CA.<br />
Methods<br />
Patients undergoing CA were randomized to a right femoral or a right radial access site. A transcranial Doppler<br />
(Embodop, DWI, Germany) with bilateral probes was used to continuously register number of particulate emboli<br />
passing each middle cerebral artery (MCA) during CA.<br />
Results<br />
Fifty patients were included, of whom 8 patients were converted from radial to femoral access and are not presented.<br />
The total number of particulate emboli was higher with the radial than with the femoral access site (10.9 ± 6.3<br />
versus 6.9 ± 4.7, p
P01:28<br />
CORONARY ARTERY BYPASS GRAFTING IN ST-MYOCARDIAL INFARCTION. AN ASSESSMENT OF<br />
AVAILABLE GUIDELINE DATA<br />
Myrmel Truls 1 , Eggen Hermansen Stig 1<br />
1) UNN, Norway<br />
Objective<br />
Guidelines <strong>for</strong> treatment of ST-elevation myocardial infarction (STEMI) have been published from the American<br />
Heart <strong>Association</strong> in 2004, and from the European Society of Cardiology in 2008. These guidelines state a lack of<br />
data on timing and selection of patients <strong>for</strong> revascularization by CABG in evolving and established ST-elevation<br />
infarctions.<br />
Methods<br />
A systematic search of PubMed, EMBASE, Clinicaltrials.gov, and Cochrane Central Register on controlled studies<br />
assessing the application of CABG as one trial arm in STEMI.<br />
Results<br />
We found no controlled trials including CABG as the main treatment in one of the trial arms in STEMI-studies. In the<br />
Shock-trial, CABG was part of the early reperfusion-strategy, and the mortality in patients treated by CABG was<br />
equal to percutaneous coronary interventions (PCI).<br />
Conclusion<br />
Data from controlled trials using CABG in STEMI are almost non existent. There are, however, general data supporting<br />
early revascularization. Thus, the use of CABG in STEMI must rely on clinical judgement integrated in a primary<br />
PCI-strategy. There is a number of observational data indicating a too restrictive use of CABG in this setting, most<br />
probably affecting patients with multi-vessel disease.<br />
P01:29<br />
RECOVERY FROM CHRONIC MYOCARDITIS AFTER 14 MONTHS OF SUPPORT BY VENTRAASSIST LVAD<br />
Gude Einar 1 , Sorensen Gro 1 , Andreassen Arne K 1 , Geiran Odd R 1 , Fiane Arnt E 1<br />
1) Oslo University Hospital, Rikshospitalet, Norway<br />
16 years old female was admitted to ourhospital with heart failure after gastroenteritis in Greece. Myocardial<br />
biopsi showed myocarditis with massive leucocyte infiltration, intracellular oedema and cellular destruction.<br />
Echocardiography showed EF 10%, biventricular failure, cardiac output 1.7 l/min.<br />
In cardiogenic shock with VT, she was supported with ECMO, IABP and levosimendan.<br />
VentrAssist LVAD was implanted Sept-07, after 20 days on ECMO.<br />
After reconstruction of femoral artery due to embolus post ECMO, and an increase in liver enzymes responding to<br />
gradual increase in VAD speed she was out of hospital after 30 days, and discharged after 45 days.<br />
From January 2008 a gradual improventent in cardiac function was observed and LVAD explant was planned.<br />
Myocardial biopsi showed chronic myocarditis and inflammatory process until she was successfully treated with<br />
steroids 60 mg tapered down to 5 mg/day after 3 weeks. LVAD removal was delayed by a gastrointestinal infection<br />
with paralytic ileus and sepsis, treated with linezolid 10 days. After recovery invasive candida albicans was detected<br />
and treated <strong>for</strong> 3 weeks without recurrence.<br />
After 413 days with Ventrassist LVAD, ECHO showed EF 50%, LVEDD 45 mm, NT-Pro BNP 35 and normal right heart<br />
hemodynamics also when reducing pump speed to 1250 rpm. VO2 20 ml/kg/min, negative Troponin T. CRP
P01:30<br />
TWO PATIENTS WITH VENTRASSIST SUCCESSFULLY TREATED FOR CANDIDAS ALBICANS.<br />
Gude Einar 1 , Bjornholt Jorgen 1 , Andreassen Arne K 1 , Sorensen Gro 1 , Geiran Odd R 1 , Fiane Arnt E 1<br />
1) Oslo University Hospital, Rikshospitalet, Norway<br />
Infections are a major cause of morbidity and mortality in patients with LVAD.<br />
Secondary to antibiotic use, invasive fungal infections are a feared and well known complication.<br />
We present the history of two Ventrassist patients with invasive candida albicans that were successfully eradicated.<br />
Patient 1. 17 year old female with Ventrassist due to acute myocarditis. Because of myocardial recovery explant of<br />
Ventrassist was planned. After an episode of gastroenteritis complicated by paralytic ileus, Enterobacter cloacae was<br />
detected on a central venous line catheter. After 10 days of treatment with meropenem, Candida albigans was found<br />
in 3 consecutive blood cultures. She was successfully treated with caspofunginacetat <strong>for</strong> 3 weeks. No recurrence of<br />
fungal infection was found in serial blood culture or on explanted LVAD. LVAD successfully explanted.<br />
Patient 2. 52 year old female with Ventrassit due to heart failure. After initial improvement she experienced a<br />
cerebral hemorrage, surgically evacuated complicated by long term respirator use. After treatment with meropenem<br />
and linezolid <strong>for</strong> 12 days <strong>for</strong> Staphylococcus aureus and Enterococcus, Candida albicans was detected in blood<br />
culture. After treatment with caspofunginacetat <strong>for</strong> 3 weeks, fungal infection was no longer detectable in serial<br />
blood cultures. Follow up 3 months. Listed <strong>for</strong> heart transplantation.<br />
Conclusion<br />
Invasive Candida albicans has occured in two of our Ventassist patients secondary to antibiotic use. Both patients<br />
were successfully eradicated without evidense of recurrence. This is in contrast to our previous experience of fungal<br />
infections were <strong>for</strong>eign material must be replaced or removed be<strong>for</strong>e eradication of infection is possible.<br />
P01:31<br />
STRESS INDUCED CARDIOMYOPATHY, TAKOTSUBO SYNDROME, COMPLICATING EARLY<br />
RECOVERY AFTER LUNG TRANSPLANTATION<br />
Hämmäinen Pekka 1 , Virolainen Juha 1 , Eriksson Heidi 1 , Lemström Karl 1 , Piilonen Anneli 1 , Harjula Ari 1 , Sipponen Jorma 1<br />
1) Helsinki University Hospital, Finland<br />
Primary graft dysfunction, infection, and acute rejection are major concerns complicating early recovery after lung<br />
transplantation. We present a case report, in which stress induced cardiomyopathy mimicked severe delayed primary<br />
lung graft failure.<br />
A 56-year-old woman with emphysema was referred <strong>for</strong> lung transplantation. Among other examinations, her<br />
cardiac ECHO showed normal right and left ventricle function, with tricuspid gradient of 31 mmHg, and LV EF<br />
61%. Her coronary angiogram was normal. As suitable donor lungs became available, her CRP was 231 and she<br />
had recurrent pneumonia. The procedure itself was uneventful, and she was extubated 7 hours later. Native lungs<br />
contained macroscopically seen foci of aspergillosis. On 17th postoperative day, she unexpectedly presented twice<br />
grand mal type seizures on ward, after which she was intubated. Next morning chest-xray showed new congestive<br />
features, and pleural effusions were drained. Oxygenation further deteriorated and CT showed extensive alveolar<br />
infiltrates. Infection as well as acute rejection were initially considered possible. However, pro-BNP value, not<br />
determined earlier, was high 12300 ng/l. Cardiac echo showed normal right heart, but left ventricular anteroapical<br />
and posterior walls were largely akinetic, and planimetric estimate of ejection fraction was only 25-30% . The<br />
overall findings were compatible with Takotsubo syndrome. LV function was supported pharmacologically, and the<br />
outcome was excellent.<br />
Takotsubo syndrome has not earlier been described to complicate lung transplantation. Newly transplanted lungs<br />
are highly vulnerable to elevated left atrial filling pressure. Correct diagnosis and avoiding additional antirejection<br />
treatment most probably contributed to eradication of aspergillus.<br />
STOCKHOLM, SWEDEN 81
P01:32<br />
RECIPIENT CELLS IN BRONCHIAL ALLOGRAFTS<br />
Vainikka Tiina 1 , Päiväniemi Outi 2 , Musilová Petra 3 , Alho Hanni 1 , Maasilta Paula 1 ,<br />
Aittomäki Kristiina 1 , Salminen Ulla-Stina 1<br />
1) Helsinki University Hospital, 2) Tampere University Hospital, Finland 3) Veterinary Research Institute, Czech Republic<br />
Lung transplantation is accepted therapy <strong>for</strong> end-stage pulmonary diseases. The main limitation on long-term<br />
survival is obliterative bronchiolits (OB). It is considered a manifestation of chronic allograft rejection. Histologically<br />
OB is manifested as epithelial cell injury, inflammation, fibrosis, and obliteration of the small airways. We studied<br />
recipient cells in bronchial allografts.<br />
29 random-bred pigs were used. Adequate, inadequate or no immunosuppression was given. 2 received control<br />
autografts and 9 male recipients received bronchial allografts from female donors. A series of allografts were<br />
transplanted subcutaneously on the ventral side of donors and were harvested serially during the follow-up.<br />
Histology (H&E) and y-chromosomes (FISH-method) using pig-spesific DNA-label were assessed. Additional 5<br />
female recipients received bronchial allografts from male donors. Samples of lung, liver, kidney and spleen were<br />
taken after 3 months to study y-chromosomes in female recipient organs (FISH).<br />
In male recipients with none or inadequate immunosuppression, rapid epithelial destruction occurred in bronchial<br />
allografts preceding obliteration. Adequate immunosuppression resulted in graft patency until 3 months (p
P01:34<br />
LONG-TERM RESULTS OF MITRAL VALVE REPAIR USING A MADE TO MEASURE GORE-TEX<br />
ANNULOPLASTY RING<br />
Javangula Kalyana 1 , Mushtaq Abid 1 , Papaspyros Sotoris 1 , Nair Unnikrishnan 1<br />
1) Leeds General Infirmary, United Kingdom<br />
Objectives<br />
This study evaluates the long-term results of mitral valve repair using a made to measure Gore-tex Annuloplasty<br />
Ring configured to the actual circumference of the valve.<br />
Methods<br />
A retrospective review was conducted of 39 consecutive patients (mean age 61.6 +/- 10.3 years; range: 26-80 years,<br />
mean Euroscore 6.5) who underwent mitral valve annuloplasty between June 1996 to December 2007. The major<br />
causes of mitral regurgitation (MR) were annular dilatation and prolapse of the posterior leaflet. Quadrangular<br />
resection of the prolapsing posterior cusp was undertaken, when necessary. A 2 mm wide made-to-measure ring<br />
created from a 0.6mm thick Gore-tex, configured to the valve circumference was inserted with interrupted ethibond<br />
sutures supporting the posterior annulus.<br />
Results<br />
One patient with Gillian Barrie Syndrome (2.5%) died late; one (2.5%) had pacemaker insertion and one (2.5%)<br />
needed valve replacement 12 months later following infection. Postoperatively at 8 years the actuarial survival was<br />
92.5% and freedom from re-operation 97.1%. Clinical and echocardiography follow-up continued <strong>for</strong> a mean period<br />
of 6.1 +/- 1.62 years (range: 1.96 to 9.55), and was complete on 21 patients. The mean NYHA functional class at<br />
follow-up was significantly lower than the preoperative score (1.32:2.65, p=0.0008, paired t-test). Pre-operatively<br />
3 patients (14%) had mild MR, 5 (24%) moderate MR and 13 (62%) severe MR. Post-operatively, 13 patients (62%)<br />
had no detectable MR and 8 (38%) had mild MR.<br />
Conclusions<br />
Mitral valve repair using a made-to-measure Gore-tex ring configured to the actual circumference of the mitral valve<br />
is safe, cost-effective, durable and reproducible.<br />
P01:35<br />
THE LEFT ATRIAL ROOF APPROACH (LARI) - AN ASSET FOR MINIMALLY INVASIVE MITRAL SURGERY<br />
Javangula Kalyana 1 , Nair Unnikrishnan 1<br />
1) Leeds General Infirmary, United Kingdom<br />
Background<br />
Adequate exposure and access is fundamental in mitral valve surgery. The conventional approach is interatrial<br />
groove using bicaval venous cannulation. The left atrial roof incision has the potential of facilitating an excellent<br />
exposure of mitral valve through a limited incision without major cardiac tissue trauma, which is particularly desirable<br />
<strong>for</strong> minimally invasive mitral surgery.<br />
We conducted this study to determine the safety, efficacy and technical ease of the LARI.<br />
Methods<br />
Retrospectively collected data of 95 consecutive patients who had mitral valve surgery by the same surgeon in the<br />
last 5 years were analysed. The patients were divided into two groups. Group 1 patients had LARI through minimally<br />
invasive sternotomy (MIS) or full sternotomy. Group 2 patients had the conventional paraseptal incision of the left<br />
atrium through a MIS or full sternotomy. The mitral valve was exposed with LARI in 81 patients (85%). Minimally<br />
invasive technique was used in 19% patients.<br />
Results<br />
More patients in the LARI group regained sinus rhythm on discharge. Concomitant procedures included AVR (25)<br />
TVR (2) AV repair (5) CABG (28) and LA and ventricular volume reduction (5). There was 1 death in group 2.<br />
Conclusions<br />
LARI is a safe technique.Compared to conventional interatrial approach, LARI has short cross clamp and bypass<br />
time. It has the added advantage of reduction in the incidence of AF, ICU stay, total hospital stay. It is feasible in<br />
redo surgery and is ideal <strong>for</strong> supervised surgical training.<br />
STOCKHOLM, SWEDEN 83
P01:36<br />
ACUTE DYSFUNCTION OF MECHANICAL AORTIC VALVE PROSTHESIS DUE TO PANNUS FORMATION<br />
Ellensen Vegard Skalstad 1 , Andersen Knut S. 1 , Segadal Leidulf 1 , Haaverstad Rune 1<br />
1) Haukeland University Hospital, Bergen, Norway.<br />
Background<br />
Acute dysfunction of mechanical prosthetic aortic valves is a life threatening complication. The common symptoms<br />
are chest pain and dyspnoea, which may be intermittent. Loss of valve click is often noticed by the patient or relatives.<br />
Patient history is of utmost importance <strong>for</strong> the diagnosis, which is confirmed by echocardiography, cinefluoroscopy or<br />
both. It is important to differentiate between thrombosis and pannus, as the <strong>for</strong>mer can be treated by thrombolysis,<br />
while the latter should be operated acutely.<br />
Patients and results<br />
We have reviewed 12 patients (13 episodes) suffering from acute dysfunction of a mechanical aortic valve caused<br />
by pannus <strong>for</strong>mation. All patients were initially operated with a monoleaflet aortic valve prosthesis (Medtronic-Hall)<br />
between 1984 and 1999. Mean age at the primary operation was 48 years (range 22-66 years). 67% were female,<br />
33% male. Mean time from primary surgery to acute dysfunction was 11.5 years (range 4.3-24.7 years). One patient<br />
had redo-surgery twice. All the reoperated patients (67%) survived. Four patients (33%) died in-hospital be<strong>for</strong>e<br />
initiation of redo-surgery. The cause of death was confirmed by autopsy.<br />
Conclusion<br />
Acute dysfunction of mechanical aortic valves caused by pannus is a life threatening complication with high mortality.<br />
As soon as the diagnosis is confirmed, redo-surgery should be per<strong>for</strong>med. In our material, the prognosis was good<br />
when the patients were reoperated in time, but bad <strong>for</strong> those who did not reach the operating theatre.<br />
P01:37<br />
EARLY HEMODYNAMIC PERFORMANCE OF PORCINE AND PERICARDIAL PROSTHESES IN<br />
AORTIC POSITION<br />
Påhlman Carin 1 , Nylander Eva 2 , Franzén Stefan 3 , Tamás Éva 3<br />
1) Faculty of Health Sciences, Linköping, 2) Dept. of Clin. Physiology Linköping,<br />
3) Dept. of Cardiothor. Surg., Linköping, Sweden<br />
Background<br />
The per<strong>for</strong>mance of the bioprosthesis after aortic valve replacement (AVR) is of major importance <strong>for</strong> the long-term<br />
outcome and quality of life. The aim of this retrospective study was to compare the early postoperative hemodynamic<br />
per<strong>for</strong>mances of pericardial versus porcine bioprostheses used in our institution.<br />
Methods<br />
The study group included 48 patients operated with isolated AVR in 2008. Hancock II (n=24) implants were compared<br />
to Perimount 2900 (n=24) matched <strong>for</strong> gender, age, body surface area and prosthesis size (labelled 21 to 27).<br />
Transthoracic echocardiography was per<strong>for</strong>med 3-12 days postoperatively.<br />
Results<br />
The pericardial group had a significant lower max velocity and mean gradient (2.62 ± 0.44 m/s, 15.8 ± 4.2 mmHg<br />
versus 3.08 ± 0.44 m/s, 21.8 ± 6.5 mmHg, p
P01:38<br />
MITRAL ANNULOPLASTY WITH A NEW MEDTENTIA RING<br />
Werkkala Kalervo 1 , Simpanen Jarmo 1 , Wirup Per 2<br />
1) Helsinki University, Finland 2) Arhus, Denmark<br />
Medtentia Annuloplasty Ring (MAR) is a new implantable annulus support ring designed to provide support <strong>for</strong> the<br />
mitral annulus. The MAR ring consists of two helical rings and is rotated in place starting at the posterior medial<br />
comissur and rotated 360 degrees so that the lower ring of the MAR slides on the ventricular aspect of the mitral<br />
annulus, underneath all chordae.The MAR ring was tested in 12 adult patients undergoing mitral valve annuloplasty.<br />
In all cases a posterior leaflet prolaps was found and a reduction annuloplasty was per<strong>for</strong>med. thereafter the MAR<br />
was implanted and the position was controlled with a dental mirror. Be<strong>for</strong>e permanent fixation of the conventional<br />
ring the MAR was removed.<br />
The mean time to implant the MAR was 1.5 min ( 0.5-5 min ). At this time no attempt to fix the MAR ring was done<br />
and it was removed. The duration of the removal time was 0.6 min (0.1-2 min).<br />
The MAR ring was easy and quick to implant and explant. During the procedure no damage to the mitral valve and<br />
chordae was noted. In all cases the ring cached all chordae. After implantation the MAR ring needs a quick fixation<br />
method to be easy and rapid method <strong>for</strong> mitral annuloplasty in conventional, minimal and robotic surgery.<br />
P01:39<br />
AORTIC VALVE REPLACEMENT IN THE ELDERLY<br />
Vainikka Tiina 1 , Soisalon-Soininen Sari 1 , Kaartinen Maija 1 , Suojaranta-Ylinen Raili 1 ,<br />
Maasilta Paula 1 , Vento Antti 1 , Salminen Ulla-Stina 1<br />
1) Helsinki University Hospital, Finland<br />
Background<br />
Aortic stenosis rate increases with age. Thus, number of patients undergoing aor-tic valve replacement (AVR) is<br />
expected to grow, when the elderly population is increasing.<br />
Methods<br />
Patients (n=145) undergoing AVR with bioprostheses 1992 - 1997 were followed. At the time of operation, 30 were<br />
> 80 years, 94 were < 80 to > 70 years, and 21 < 70 years old. A follow-up control including echocardiographic<br />
examination took place at least 5 years postoperatively. Follow-up continued until July 31, 2006.<br />
Results<br />
In the oldest group, 30-day mortality was 3.3% and 6.4% in the middle group. In the middle group, 5 valve-related<br />
reoperations were per<strong>for</strong>med. At time of follow-up, 84 (58 %) patients were alive and 60 (71%) attended. LVEF<br />
was improved being > 60% in all groups and the aortic valve gradient was lower than preoperatively in all and most<br />
decreased in the oldest group (p
P01:40<br />
SVO2 A MARKER WITH EXCELLENT SENSITIVITY AND SPECIFICITY FOR CARDIAC MORTALITY AFTER<br />
SURGERY FOR AORTIC STENOSIS<br />
Svedjeholm Rolf 1 , Holm Jonas 1 , Vanky Farkas 1 , Håkanson Erik 1<br />
1) Linköping University Hospital, Sweden<br />
Objective<br />
Adequate monitoring of hemodynamic state is essential after cardiac surgery and vital <strong>for</strong> medical decision making<br />
particularly concerning hemodynamic management. Un<strong>for</strong>tunately commonly used methods to assess hemodynamic<br />
state are poorly documented with regard to outcome. Mixed venous oxygen saturation (SvO2) was there<strong>for</strong>e<br />
investigated after cardiac surgery.<br />
Methods<br />
Detailed data regarding mortality was available on all patients undergoing aortic valve replacement <strong>for</strong> isolated<br />
aortic stenosis during 1995 - 2000 in the southeast region of Sweden (n=396). SvO2 was routinely measured on<br />
arrival to intensive care unit (ICU) and registered in a data base. A receiver operating characteristics (ROC) analysis<br />
of SvO2 in relation to mortality related to cardiac failure and all cause mortality within 30 days was per<strong>for</strong>med.<br />
Results<br />
Area under the curve (AUC) was 0.97 (95% CI 0.96-1.00) <strong>for</strong> mortality related to cardiac failure (p=0.001) and 0.76<br />
(95% CI 0.53-0.99) <strong>for</strong> all cause mortality (p=0.011). The best cut off <strong>for</strong> mortality related to cardiac failure was<br />
SvO2 53.7% with a sensitivity of 1.00 and a specificity of 0.94. Negative predictive value was 100%.<br />
The best cut off <strong>for</strong> all cause mortality was SvO2 58.1% with a sensitivity of 0.75 and a specificity of 0.84. Negative<br />
predictive value was 99.4%<br />
Conclusions<br />
SvO2 on arrival to ICU after surgery <strong>for</strong> aortic stenosis demonstrated excellent sensitivity and specificity <strong>for</strong><br />
postoperative mortality related to cardiac failure and fairly good AUC <strong>for</strong> all cause mortality with excellent negative<br />
predictive value.<br />
P01:41<br />
RESTORING SUBVALVAR CONTINUITY BY REIMPLENTING STRUT CHORDA IN THE SETTING OF<br />
RHUMATIC MITRAL VALVE REPLACEMENT1<br />
Kargar Faranak 1 , Samiei Niloofar 1 , Mohebi Ahmad 2 , Noohi Freidoun 1 , Aazami Mathias 1<br />
1) Shahed Rajaei Heart Hospital, Iran<br />
Introduction<br />
Preserving mitral subvalvar continuity is technically challenging in the setting of rheumatic heart valve disease. We<br />
report on a new technique to restore mitral subvalvar continuity by re-implanting the strut chorda that are primary<br />
mediators of LV-central fibrous body interplay.<br />
Patients and methods<br />
During <strong>2009</strong>, 7 patients (mean age: 48.6 ± 12.6 y.o; female: 57%; mean LVEF: 44.29 %; mean PAP: 51 mmHg;<br />
mean logistic Euroscore: 9.5 ± 8 %) with rheumatic heart valve disease (mitral stenosis: 43%; mitral regurgitation:<br />
14%; mitral stenosis and regurgitation: 43%) underwent mitral valve replacement using the current technique that<br />
consists on preserving mitral subvalvar continuity by reimplanting mitral strut chorda to the mitral annulus and sitting<br />
a mechanical bi-leaflet valve prosthesis in an intra-annular position.<br />
Results<br />
All patients survived on operation; displaying an uneventful postoperative course. 5 patients (71.4%) required one<br />
or more concomitant procedures. The mean pump and ischemic times were 269 and 193 minutes respectively. At<br />
the time of discharge the means LVEF and trans-mitral prosthetic gradient were 42.14 % and 4.2 mmHg (ranged<br />
from 3 to 7) respectively. The re-implanted anterior and posterior strut chorda were identified in all patients on<br />
postoperative echocardiography without inferring with prosthetic valves leaflets.<br />
Conclusions<br />
Restoring the mitral subvalvar continuity by re-implanting the strut chorda is safe and reproducible in patients with<br />
rheumatic heart valve disease. The latter may be more physiologic rather than re-approximating marginal chorda to<br />
the annulus in terms of preservation of LV function that needs to be further investigated.<br />
86 www.sats<strong>2009</strong>.org
P01:42<br />
DAVID PROCEDURE: EARLY AND MID-TERM RESULTS FIVE YEAR EXPIERIENCE<br />
Karciauskas Dainius 1 , Benetis Rimantas 1 , Egle Ereminiene 1 , Povilas Jakuska 1 , Sarunas Kinduris 1<br />
1) Kaunas Medical University, Lithuania<br />
Background<br />
Aortic valve sparing surgery offers a unique opportunity to preserve the aortic valve of patients with aortic root<br />
disease.<br />
Methods<br />
Between January 2004 and April <strong>2009</strong>, David procedure was per<strong>for</strong>med in 21 patients of 827 patients whom<br />
underwent aortic root and valve surgery in the Heart Center of Kaunas University of Medicine. Study protocol<br />
included clinical data (age), patients functional status (NYHA), left ventricule mass index, postoperative major<br />
adverse effects: reoperations <strong>for</strong> bleeding, stroke and lethal outcomes. Patients were observed up to 30 days after<br />
surgery <strong>for</strong> early results and annually <strong>for</strong> mid-term results.<br />
Results<br />
Mean age in group was 51.9 ± 3.3 y. Preoperative status (NYHA) of group was 2.8 ± 0.15. Early mortality rates,<br />
observed within the first 30 days, were only after emergency surgery due to Acute dissection (n=1) and there were<br />
no late mortality events. Reoperation rates due to bleeding events were noted only within first 12 hours: n=4. Annual<br />
doppler echocardiography revealed mild to moderate aortic insufeciency in three patients one year after surgery<br />
with left ventricule mass index reduction from 186.8 ± 13.3 g/m2 to 128.4 ± 12 g/m2. Neither thromboembolic<br />
complications nor stroke events were noted.<br />
Conclusions<br />
Aortic valve-sparing operations according to clinical outcomes are safe but there are some issues related with aortic<br />
valve competence which need full follow-up due to small cohort of patients and sufficient interval of time.<br />
P01:43<br />
TRANSCATHETER AORTIC VALVE IMPLANTATION IN HIGH-RISK SURGICAL CANDIDATES WITH LOW<br />
RISK SCORES<br />
Ahn Henrik 1 , Baranowski Jacek 1 , Freter Wolfgang 1 , Nielsen Niels Erik 1 , Nylander Eva 1 , Tamas Eva 1 , Wallby Lars 1<br />
1) Linköping Heart Center, Sweden<br />
There are patients (pts) with expected high risk at operation that does not get high-risk scores from the traditional<br />
measures as STS or logEuroscores. Among our first 15 pts who underwent a transcatheter aortic valve implantation<br />
there were 3 who principally were accepted after an extensive evaluation of the expected risk of an open chest<br />
operation.<br />
Material and methods<br />
The first pt, a 75 year old man, had been operated 4 years be<strong>for</strong>e with a biological stented prosthesis (Perimount<br />
23 mm) and CABG. The operation was very complicated and the prosthesis became increasingly stenotic. The<br />
other 2 pts, a 60 years old woman and a 66 years old man, had been treated with full dose chest radiation due to<br />
previous malignancies. Both had developed heart failure with aortic stenosis as dominant lesion but mitral valve<br />
disease and secondary tricuspid insufficiency contributed to the clinical picture. The man had previously undergone<br />
a pericardectomy and PCI three times.<br />
The woman had a new malignancy diagnosed, curable but needing surgery without delay.<br />
Results<br />
The valve-in-valve procedure by the transapical approach was uneventful with good position and function of the new<br />
valve (Edwards Lifesciences, Sapien 23 mm). The woman got a Sapien 26 mm valve with good functional result.<br />
The third patient deteriorated quickly after the periods with rapid pacing needing resuscitation in combination with<br />
standard drug treatment. He recovered and showed no neurological symptoms in the early postop period.<br />
Conclusion<br />
Challenging intraoperative problems were avoided by this new catheter based technology.<br />
STOCKHOLM, SWEDEN 87
P01:44<br />
SUBCLAVIAN ARTERY APPROACH IN TRANSCATHETER AORTIC VALVE IMPLANTATION<br />
Holm Peter 1 , Jönsson Anders 1<br />
1) Karolinska University Hospital, Sweden<br />
Objectives<br />
Transcatheter aortic valve implantation (TAVI) has evolved as a therapeutic option with reproducibly good results in<br />
patients (pts) considered to be at high risk <strong>for</strong> complications from conventional surgical valve replacement. Several<br />
thousands of pts have been treated with TAVI worldwide. The experience at our centre since February 2008 is<br />
limited to the CoreValve system. The purpose of this study was to report our experience with TAVI using the left<br />
subclavian artery as vascular access.<br />
Methods and Results<br />
A total of 55 pts with a mean age of 82±6 years and a logistic EUROSCORE of 24±11% underwent TAVI using the<br />
CoreValve prosthesis. In 50 pts the prosthesis was delivered using a transfemoral approach. In 5 pts (3 male) the<br />
left subclavian artery was used <strong>for</strong> access. The decision to use the subclavian artery approach was based on severe<br />
aortic angulations in two patients and inability to create femoral access because of small, calcified or tortuous<br />
femoral arteries in three pts. There was no 30-day mortality in any of the pts operated on using the subclavian artery<br />
as vascular access.<br />
Conclusions<br />
The left subclavian artery can be used as an alternative to create access in patients unsuitable <strong>for</strong> TAVI via the<br />
femoral arteries. This access has in our initial experience some advantages when compared to the femoral artery<br />
approach. The short and straight distance from the introducer positioned in the subclavian artery down to the aortic<br />
annulus offers enhanced stabilization during the expansion of the valve.<br />
P01:45<br />
CAN A PHYSICAL MOBILISATION PROGRAM FOLLOWING OPEN HEART SURGERY INFLUENCE ON<br />
POSTOPERATIVE ROUTINES?<br />
Haukeland Unni Kleppe 1 , Oterhals Kjersti 1 , Drevdal Julie 1 , Lygren Heidi 1 , Njåstad Anita 1 ,<br />
Segadal Leidulf 1 , Haaverstad Rune 1<br />
1) Haukeland University Hospital, Norway<br />
Background and objectives<br />
Pulmonary complications are frequent following open heart surgery. Physical mobilisation is of prime importance<br />
to prevent postoperative respiratory complications. The main objective was to study whether a standard nursing<br />
protocol <strong>for</strong> mobilising patients could stimulate active and early mobilisation in general, and additionally reduce<br />
postoperative pulmonary complications.<br />
Methods<br />
According to the new protocol, minimum mobilisation of 57 patients (intervention group) included sitting in a chair<br />
30 min x 3 1. po. day and 60 min x 3 the 2. day. From day 3 patients should walk about and stay out of bed most<br />
of the day. Retrospectively complications were compared with a matched group of 59 patients (control group) with<br />
routine treatment. The mobilisation was registered in a data <strong>for</strong>m. Clinical and demographic data were collected<br />
from patient files.<br />
Results<br />
The groups were similar with regards to age, gender and preop. risk factors (EuroScore). Mean age of all patients<br />
was 68 ± 12 years, range 27-89 years, and 72 % were men. The study revealed that systemizing respiratory<br />
complications is a difficult task and this will be further analyzed. No differences were found between the groups with<br />
respect to how many times patients were mobilised the first three po. days. However, patients in the intervention<br />
group stayed out of bed <strong>for</strong> longer periods both on day 1 (p = 0.018) and day 2 (p < 0.0001).<br />
Conclusions<br />
A postoperative nursing protocol may improve mobilisation of patients following heart surgery. Increased knowledge<br />
and focus on mobilisation may have influenced positively on mobilising routines on the ward.<br />
88 www.sats<strong>2009</strong>.org
P01:46<br />
TELEPHONE SUPPORT FOR CARDIAC SURGERY PATIENTS AT HOME POST DISCHARGE FROM HOSPITAL<br />
Thorsteinsdottir Steinunn Arna 1<br />
1) Landspitali University Hospital, Iceland<br />
Aims<br />
The aim of this quality project was to explore the educational needs, provide general support and evaluate the<br />
usefulness of telephone-support among cardiac surgery patients one to two weeks post discharge from Landspitali<br />
University Hospital (LUH).<br />
Method<br />
A descriptive exploratory method was used. All cardiac surgery patients (n=17) who were discharged from the<br />
heart-surgery unit at LUH over a one month period in spring <strong>2009</strong> received a phone call from a nurse at the unit.<br />
They received the call 6-15 days post-discharge. A purpose-made checklist was used to collect data on educational<br />
need. The list included questions on physiological and psychological issues. In<strong>for</strong>mation was also sought on use<br />
of health care services post-discharge, satisfaction with education received at the hospital and usefulness of the<br />
telephone call.<br />
Findings<br />
This intervention consisted of patient education, encouragement and support, screening <strong>for</strong> potential complications<br />
and facilitating access to various agents in the healthcare system. Patients expressed satisfaction with the phonecall<br />
and evaluated it as necessary even though they were content with the discharge education received. All of them<br />
had some questions or needed confirmation of their condition as being normal. Pain, problems with the operated<br />
leg, fatigue, oedema and psychological problems were the most common signs and symptoms these patients<br />
experienced.<br />
Conclusion<br />
Telephone-support seems to be a useful intervention <strong>for</strong> this patient group and improves their satisfaction and<br />
security at home. Many un<strong>for</strong>eseen questions and problems arise after discharge and addressing them timely may<br />
enhance recovery and prevent complications to become severe.<br />
P01:47<br />
THE MEMORIES AND EXPERIENCES OF PATIENTS AFTER HEART-SURGERY, AN INTERVIEW STUDY<br />
Sundh Marie 1 , Rylander Hagson Pauline 1<br />
1) Sweden<br />
Previous studies have shown that patients become strongly affected after heart-surgery and a stay in an intensivecare<br />
unit. The aim of this study was to describe the patient’s experiences and memories after open-heart-surgery.<br />
Four patients where included in the study and in-depth-interviews where made in the fourth to fifth day after surgery.<br />
A Qualitative content analysis of the interviews where made, which showed that the patients experienced several<br />
mixed feelings related to the surgery, such as pleasure and anxiety. They experienced how their abilities changed<br />
after the surgery with symptoms as confusion and amnesia. The experiences where affected by factors out of the<br />
patient’s control, such as the routines and environment of the ward. To be cared <strong>for</strong> in an intensive-care unit after<br />
heart surgery was described as a big incident in life and the patients felt the need of empathy, compassion and<br />
warmth. As employees of the ward we were capable of providing many of these needs, but we must not <strong>for</strong>get about<br />
the seriousness of the situation these patients are experiencing and we must never consider it to be a matter of<br />
routine. If we do so, it will show in our actions during the care of these patients and it will contribute to a negative<br />
experience of the patients.<br />
STOCKHOLM, SWEDEN 89
P01:48<br />
NURSING STUDY 30 DAYS AFTER DISCHARGE.<br />
Joergensen Inge Selchau 1 , Tracey Anita 2<br />
1) Aarhus University Hospital, Skejby, 2) Aalborg Hospital, Denmark<br />
Introduction<br />
In connection with The Danish On-pump Off-pump Randomization Study (DOORS) the project nurse contacts the<br />
patient by telephone 30 days after the heart operation. In connection with these interviews the project nurse has<br />
noticed that a lot of the patients experienced different types of problems which the nurses previously didn’t realise<br />
the extent of. The problems occur within the first month following the operation.<br />
Hypothesis<br />
Patients who have undergone a heart operation have problems of physical, psychological and social nature.<br />
Aim<br />
The aim of the investigation is to get a greater kvowledge about and gain an increased insight into the physical,<br />
psychological and social state of health of the patients. In the future this knowledge will be used in the guidance and<br />
in<strong>for</strong>mation the heart patient receives during hospitalization in order that they are better prepared <strong>for</strong> discharge and<br />
their future life with a chronic illness.<br />
Method<br />
Telephone interviews with 350 patients based on a semi-structured interview guide. Focus is on the topics of pain<br />
- medicine administration - compliance, physical activity - exercise, breathing, nutrition - appetite - weight, sleep,<br />
health and discharge. Data will be analysed be means of quantitative content analysis.<br />
Results and conclusion<br />
Quantitative content analysis of the results of the investigation is expected to be carried out during the autumn of<br />
<strong>2009</strong>. Following which conclusion will be drawn and in perspective might have an influence on the care and treatment<br />
of the heart patients in the future.<br />
P01:49<br />
INTRAOPERATIVE CONTAMINATION OF SURGICAL INSTRUMENTS<br />
Persson Jenny 1<br />
1) Karolinska Universitetssjukhuset i Solna, Sweden<br />
Background<br />
Every year 2-5% of all surgical patients in the USA suffers from surgical wound infections, resulting in 500.000<br />
infections and 1.6 billion dollar in additional costs. These complications also results in higher mortality as a complication<br />
to surgery. Several factors are known to influence on the risk of surgical wound contaminations. Pathogens can<br />
contaminate surgical wounds by surgical instruments, which are exposed by all the factors <strong>for</strong> contaminations in the<br />
operating theatre. However, there are very few articles that have study the prevalence of microorganisms on surgical<br />
instruments.<br />
Objectives<br />
To study the prevalence of microorganisms on frequently used surgical instruments in aortic valve surgery with<br />
replacement to a biological implant.<br />
Do microorganisms occur on surgical instruments?<br />
What types of microorganisms occurs on surgical instruments?<br />
Does any step in the intraoperative procedure influence more than another step on the risk of contamination?<br />
Method<br />
The study is planned to be per<strong>for</strong>med with a quantitative method on 20 operations. To handle all factors of<br />
contaminations, and to avoid influence of unwanted factors, the study has to be strictly standardized and controlled<br />
by a test protocol. To determine average and nominal time <strong>for</strong> the predefined steps in the intraoperative procedure,<br />
and to validate the optimal standardized sample collection technique <strong>for</strong> swabbing the instruments, two pilot<br />
studies will be per<strong>for</strong>med. The two most frequently used instruments will be swabbed be<strong>for</strong>e or after a predefined<br />
intraoperative step and samples will be cultivated <strong>for</strong> identification and count.<br />
90 www.sats<strong>2009</strong>.org
P01:50<br />
FINE FEATHERS MAKE FINE BIRDS.<br />
Tracey Anita 1 , Rasmussen Tina Seidelin 2 ,<br />
1) Aalborg Hospital, Aarhus University Hosp, 2) Aalborg Hospital, Denmark<br />
Background<br />
The focus of the study is on the patient’s experience of wearing patient clothing. Patient clothing can be compared<br />
with night wear as it is designed <strong>for</strong> being worn in bed. The experience of wearing patient clothing is described as a<br />
feeling of being naked, anonymous or as if ones personality is camouflaged. Clothing is our cultural skin which finds<br />
expression in the way we’re dressed. By wearing patient clothing the patient shows that he belongs to the patient<br />
culture. Wearing patient clothing can result in decrease in spontaneous activity.<br />
- Why do patients wear patient clothing at all?<br />
- Does patient clothing get like a type of uni<strong>for</strong>m that makes the patient anonymous?<br />
- How can it be that the patient doesn’t choose to wear their own clothes?<br />
- We experience that patient’s behaviour in connection with clothing is distinctly different during hospitalization than<br />
it is in private. Would one <strong>for</strong> example buy bread in the local bakers wearing only nightclothes?<br />
Aim<br />
The Aim is to investigate how patients in a Danish Hospital experience wearing patient clothing during hospitalization<br />
in a post-operative ward.<br />
Method<br />
Participant observation and semi-structured interview are the chosen qualitative methods that are used to create<br />
the empirical material. Each observer observes five patients in their own ward during daytime hours. Following this<br />
ten other patients are interviewed and the interviews are transcribed.<br />
Results<br />
The investigation is expected to be carried out during <strong>2009</strong> with subsequent reporting during the summer of 2010.<br />
P01:51<br />
IS MINI-CPB REALLY LESS HARMFULL THAN THE CONVENTIONAL CPB? THE RESULTS OF<br />
IMMUNOLOGICAL STUDY.<br />
Lonsky Vladimir 1 , Krejsek Jan 1 , Kudlova Manuela 1 , Kolackova Martina 1 , Mandak Jiri 1 , Kubicek Jaroslav 1 , Volt Martin 4<br />
1) Palacky University Hospital, Czech Republic<br />
Background<br />
The cardiac surgical intervention with the use of CPB is accompanied by the activation of complex immunity arm.<br />
This feature is associated with both pro-inflammatory and anti-inflammatory changes. The expression of various pro-<br />
and anti-inflammatory markers were compared between “conventional” and “mini” patients to evaluate potential<br />
benefits of mini-CPB.<br />
Methods<br />
54 patients who underwent primary isolated CABG were prospectively studied. 26 patients (MINI) were operated<br />
upon using a closed circuit IDEAL/SYNERGY, Sorin, Italy, second group of 28 patients (CPB) were operated with<br />
the use of conventional extracorporeal circulation with hardshell reservoir. Peripheral venous blood samples were<br />
collected be<strong>for</strong>e and after surgery and at the 1st, 3rd and 7th postoperative day. The expression of sTNF-alfa R<br />
80kDa, sTNF- alfa R 60kDa, IL-6, IL-10, PMN elastase, MCP-1 as plasmatic markers and CD64 (monocytes and<br />
granulocytes) CD163 (monocytes and granulocytes), CD95 (monocytes and granulocytes), TLR2 (monocytes and<br />
granulocytes), CD254 (monocytes and granulocytes) as cellular markers was studied with the use of flow cytometry<br />
or ELISA assay.<br />
Results<br />
Summarizing our results we can say that almost all studied pro- and anti-inflammatory markers were found to be<br />
significantly less activated in MINI group comparing to conventional CPB at the end of surgery (IL-6 p
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SAS_S14_A5:AD 11/05/09 13:29 Side 1<br />
Dear Participant,<br />
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