Tuesday AM 11:06 217. Detecting Myocardial Ischemia at Rest with Cardiac Phase-Resolved BOLD MRI: Early Findings Sotirios Athanasios Tsaftaris 1,2 , Veronica Rundell 2 , Xiangzhi Zhou 2 , Ying Liu 2 , Richard Tang 2 , Debiao Li 2 , Rohan Dharmakumar 2 1 2 Electrical Engineering & Computer Science, Northwestern University, Evanston, IL, USA; Radiology, Northwestern University, Chicago, IL, USA 11:18 218. Methods for Quantification of Absolute Myocardial Oxygen Consumption with 17 O-CMR David Muccigrosso 1 , Xiang He 2 , Dana Abendschein 1 , Adil Bashir 1 , Pradeep Gupte 3 , Wei Chen 4 , Robert J. Gropler 1 , Jie Zheng 1 1 2 3 4 Washington University School of Medicine, St. Louis, MO, USA; University of Pittsburg; Rockland Technimed, Ltd.; University of Minnesota 11:30 219. Rapid CINE Myocardial T 2 * Mapping at 7T Fabian Hezel 1 , Peter Kellman 2 , Christof Thalhammer 1 , Wolfgang Renz 3 , Thoralf Niendorf 1,4 1 Berlin Ultrahigh Field Facility, Max Delbrueck Center for Molecular Medicine, Berlin, Germany; 2 Laboratory of Cardiac Energetics, National Institutes of Health/NHLBI, Be<strong>the</strong>sda, MD, USA; 3 Siemens Medical Systems, Erlangen, Germany; 4 Experimental & Clinical Research Center (ECRC), Charité Campus Buch, Humboldt-University, Berlin, Germany 11:42 220. Pyruvate is Superior to Glucose in Supporting Metabolism of Machine Perfused Donor Hearts for Transplantation Michael Cobert 1 , Matthias Peltz 1 , Mat<strong>the</strong>w Merritt 2 , LaShondra West 1 , Michael E. Jessen 1 1 Cardiovascular & Thoracic Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA; 2 Advanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA 11:54 221. Myocardial ASL Perfusion Reserve Test Detects Angiographic CAD in Initial Cohort of 29 Patients Zungho Zun 1 , Terrence Jao 1 , Padmini Varadarajan 2 , Ramdas G. Pai 3 , Eric C. Wong 4 , Krishna S. Nayak 1 1 Department of Electrical Engineering, University of Sou<strong>the</strong>rn California, Los Angeles, CA, USA; 2 Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA, USA; 3 Division of Cardiology, Loma Linda University Medical Center, Loma Linda , CA, USA; 4 Departments of Radiology & Psychiatry, University of California, San Diego, La Jolla, CA, USA 12:06 222. Self-Gated Cardiac Perfusion MRI Edward DiBella 1 , Ganesh Adluru 2 , Liyong Chen 3 , Chris McGann 4 1 2 3 4 University of Utah, Salt Lake City, UT, USA; Radiology, University of Utah; Bioengineering, University of Utah; Cardiology, University of Utah 12:18 223. Endo<strong>the</strong>lial Progenitor Cells Mediated Improvements in Post-Infarct Left Ventricular Myocardial Blood Flow Estimated by Spin Labeling CMR Hua-Lei Zhang 1,2 , Hui Qiao 1 , Rachel S. Frank 1 , Stephanie Eucker 2 , Bin Huang 1 , William M. Armstead 3 , Victor A. Ferrari 4 , Jonathan A. Esptein 4 , Rong Zhou 1 1 Laboratories of Molecular Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA; 2 Department of Bioengineering, School of Engineering & Applied Science, University of Pennsylvania, Philadelphia, PA, USA; 3 Department of Anes<strong>the</strong>sia, University of Pennsylvania, Philadelphia, PA, USA; 4 Department of Medicine (Division of Cardiovascular Medicine), University of Pennsylvania, Philadelphia, PA, USA Endogenous Contrast Mechanisms: MT & Relaxometry Room 518-A-C 10:30-12:30 Moderators: Karla L. Miller & Bruce Pike 10:30 224. Fast Bound Pool Fraction Imaging of <strong>the</strong> In Vivo Rat Brain: Assocation with Myelin Content & Validation in <strong>the</strong> C6 Glioma Model Hunter R. Underhill 1 , Robert C. Rostomily 1 , Andrei M. Mikheev 1 , Chun Yuan 1 , Vasily L. Yarnykh 1 1 University of Washington, Seattle, WA, USA 10:42 225. Modeling & Measuring <strong>the</strong> Myelin G-Ratio Nikola Stikov 1 , Lee M. Perry 2 , Aviv Mezer 2 , John M. Pauly 3 , Brian A. Wandell 2 , Robert F. Dougherty 2 1 Montreal Neurological Institute, McGill University, Montreal, QC, Canada; 2 Psychology, Stanford University, Stanford, CA, USA; 3 Electrical Engineering, Stanford University, Stanford, CA, USA 10:54 226. Paradoxical Changes in Magnetization Transfer Ratio & Susceptibility Contrast in <strong>the</strong> Motor Cortex Olivier E. Mougin 1 , Samuel J. Wharton 1 , Rosa M. Sanchez Panchuelo 1 , Richard W. Bowtell 1 , Penny A. Gowland 1 1 Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom 32
11:06 227. Fast Macromolecular Proton Fraction Mapping From a Single Off-Resonance Magnetization Transfer Measurement Vasily L. Yarnykh 1 1 Radiology, University of Washington, Seattle, WA, USA Tuesday AM 11:18 228. Origins of <strong>the</strong> Ultrashort-T 2 1 H NMR Signals in Myelinated Nerve: A Direct Measure of Myelin Content? Robert Adam Horch 1,2 , John C. Gore 2,3 , Mark D. Does 1,2 1 Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; 2 Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, USA; 3 Radiology & Radiological Sciences, Vanderbilt University, Nashville, TN, USA 11:30 229. New MRI Contrasts in Experimental Stroke: What Do We Measure with RAFF & ZAPI? Johanna Närväinen 1 , Kimmo Jokivarsi 2 , Timo Liimatainen, Olli Gröhn, Risto A. Kauppinen 3 1 A. I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland; 2 Massachusetts General Hospital; 3 Dartmouth College, USA 11:42 230. Observation of Myelin Water at Ultra-Short Echo Time by Longitudinal Relaxographic Imaging with Spin- Echo Center-Out EPI (DEPICTING) Christian Labadie 1,2 , William D. Rooney 3 , Charles S. Springer, Jr. 3 , Jing-Huei Lee 4 , Monique Aubert-Frécon 2 , Stefan Hetzer 5 , Toralf Mildner 1 , Harald E. Möller 1 1 Max Planck Institute for Human Cognitive & Brain Sciences, Leipzig, Germany; 2 Laboratoire de Spectrométrie Ionique et Moléculaire, Université Claude Bernard Lyon 1, France; 3 Oregon Health & Science University, Portland, OR, USA; 4 Biomedical Engineering, University of Cincinnati, OH, USA; 5 Bernstein Center for Computational Neuroscience, Berlin, Germany 11:54 231. 3D Quantitative Imaging of T 1rho & T 2 Weitian Chen 1 , Atsushi Takahashi 1 , Eric Han 1 1 Global Applied Science Laboratory, GE Healthcare, Menlo Park, CA, USA 12:06 232. Is Iron <strong>the</strong> Source of Post Mortem Susceptibility Contrast in <strong>the</strong> Brain? Ferdinand Schweser 1,2 , Christian Langkammer 3,4 , Andreas Deistung 1 , Nikolaus Krebs 4 , Walter Goessler 5 , E. Scheurer 4 , K. Yen 4 , Franz Fazekas 3 , Jürgen R. Reichenbach 1 , Stefan Ropele 3 1 2 Medical Physics Group, Dept. of Diagnostic & Interventional Radiology 1, Jena University Hospital, Jena, Germany; School of Medicine, Friedrich Schiller University of Jena, Jena, Germany; 3 Dept. of Neurology, Medical University of Graz, Graz, Austria; 4 5 Ludwig Boltzmann Institute for Clinical-Forensic Imaging, Graz, Austria; Institute of Chemistry, Analytical Chemistry, University of Graz, Graz, Austria 12:18 233. Three Dimensional T 2prep Spiral Imaging with Efficient Brain Coverage For Myelin Water Quantification: Validation At 1.5 Tesla Thanh D. Nguyen 1 , Cynthia Wisnieff 2 , Mitchell Cooper 2 , Dushyant Kumar 1 , Ashish Raj 1 , Martin R. Prince 1 , Yi Wang 1 , Tim Vartanian 3 , Susan A. Gauthier 3 1 Radiology, Weill Cornell Medical College, New York, NY, USA; 2 Biomedical Engineering, Cornell University, Ithaca, NY, USA; 3 Neurology, Weill Cornell Medical College, New York, NY, USA 33