- Page 1 and 2: World Cancer Research Fund Food, Nu
- Page 3 and 4: Please cite the Report as follows:
- Page 5 and 6: Preface I am very grateful to the s
- Page 7 and 8: Contents Preface i v Contents v i A
- Page 9 and 10: Panel viii FOOD, NUTRITION, PHYSICA
- Page 11 and 12: x FOOD, NUTRITION, PHYSICAL ACTIVIT
- Page 13 and 14: xii FOOD, NUTRITION, PHYSICAL ACTIV
- Page 15 and 16: xiv FOOD, NUTRITION, PHYSICAL ACTIV
- Page 17: xvi FOOD, NUTRITION, PHYSICAL ACTIV
- Page 21 and 22: xx FOOD, NUTRITION, PHYSICAL ACTIVI
- Page 23 and 24: xxii FOOD, NUTRITION, PHYSICAL ACTI
- Page 25 and 26: xxiv FOOD, NUTRITION, PHYSICAL ACTI
- Page 27 and 28: ����������� P
- Page 29 and 30: important and can be modified. Thes
- Page 31 and 32: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 33 and 34: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 35 and 36: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 37 and 38: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 39 and 40: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 41 and 42: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 43 and 44: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 45 and 46: Data from World Health Organization
- Page 47 and 48: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 49 and 50: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 51 and 52: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 53 and 54: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 55 and 56: CHAPTER 1 • INTERNATIONAL VARIATI
- Page 57 and 58: C HAPTER 2 • THE CANCER PROCESS T
- Page 59 and 60: C HAPTER 2 • THE CANCER PROCESS s
- Page 61 and 62: C HAPTER 2 • THE CANCER PROCESS 2
- Page 63 and 64: C HAPTER 2 • THE CANCER PROCESS B
- Page 65 and 66: C HAPTER 2 • THE CANCER PROCESS B
- Page 67 and 68: C HAPTER 2 • THE CANCER PROCESS o
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C HAPTER 2 • THE CANCER PROCESS N
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C HAPTER 2 • THE CANCER PROCESS 4
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C H A P T E R 3 Judging the evidenc
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Box 3.1 Issues concerning interpret
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Box 3.2 Dose response ‘Dose respo
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Box 3.4 Systematic literature revie
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harvesting conditions, animal feed,
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3.4.2 The ‘portfolio’ approach
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Box 3.8 Criteria for grading eviden
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excluded. Usually this evidence cam
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EVIDENCE AND JUDGEMENTS PART 2 64 I
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C H A P T E R 4 Foods and drinks Th
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countries with hot, damp climates a
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70 Box 4.1.4 Aflatoxins Mycotoxins
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72 Figure 4.1.1 Dietary fibre and c
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4.2). All of these are highest in d
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VEGETABLES, 1 FRUITS, 1 PULSES (LEG
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content, and the oils produced from
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80 Box 4.2.4 Foods containing dieta
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4.2.4.2 Specific Considerations spe
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assessed carrots, but some looked a
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Non-starchy root vegetables and tub
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cohort and case-control data on gre
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Non-starchy vegetables and fruits A
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Green, leafy vegetables All three c
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94 Figure 4.2.16 Garlic consumption
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studies, 33 85 86 88 90 97 105 111
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cancer cases) showed a statisticall
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504 508 511 506 and in men but not
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Figure 4.2.29 Carotenoids and lung
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Figure 4.2.31 Lycopene and prostate
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somal breakage and rearrangement ca
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Figure 4.2.35 Vitamin C and oesopha
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Dietary selenium One cohort study s
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Selenoproteins appear to reach thei
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tected against cancers of the liver
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These animal foods are sources of p
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those of birds; because they are ge
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Box 4.3.5 Cantonese-style salted fi
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The single cohort study showed incr
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124 There is limited evidence, most
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Figure 4.3.11 Salted fish and nasop
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128 There is limited, inconsistent
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From the late 19th century, consump
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Seven case-control studies showed i
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on three and two cohort studies, re
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heart disease, and cancers of some
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4.5.4.2 Specific Some consideration
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cause of lung cancer or postmenopau
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taste preference promotes energy co
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Box 4.6.4 Refrigeration Freezing an
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preserved foods may be eaten more b
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Water is essential. Without water,
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specifically the infusion of the dr
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4.7.4.2 Specific Classification. Di
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cant decreased risk in men. 74 Meta
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Figure 4.7.4 Maté and oesophageal
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since the effects on mood of the fe
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Figure 4.8.1 Alcoholic drinks and m
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showed increased risk, which was st
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94 106 184 198 studies were in the
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control studies, 280 282 317 318 33
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influencing hormone levels and oest
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Spirits Two cohort studies6 486 425
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Practically all food and drink is c
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Box 4.9.2 ‘Organic’ farming So-
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Box 4.9.4 Water fluoridation In the
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and in these cases, the Panel’s j
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corresponding to judgements of ‘c
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Box 4.10.1 Food fortification Food
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4.10.6.4.1 Retinol Skin Two RCTs in
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Table 4.10.4 Beta-carotene suppleme
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analysis was possible on two of the
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4.11 Dietary patterns The nature, q
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elatively costly. In some tradition
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meat, fish, and olive oil) was asso
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meals. But none of these studies de
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CHAPTER 5 • PHYSICAL ACTIVITY PHY
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CHAPTER 5 • PHYSICAL ACTIVITY Box
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CHAPTER 5 • PHYSICAL ACTIVITY Fig
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CHAPTER 5 • PHYSICAL ACTIVITY Fou
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CHAPTER 5 • PHYSICAL ACTIVITY the
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CHAPTER 5 • PHYSICAL ACTIVITY cer
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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CHAPTER 6 • BODY COMPOSITION, GRO
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C H A P T E R 7 Cancers Every year
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7.1.1 Trends, incidence, and surviv
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Studies that reported on combined i
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7.2 Nasopharynx Cancer of the nasop
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Six case-control studies investigat
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epithelial cells, from which adenoc
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7.3.5.4 Foods containing folate (Al
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oesophageal cancer. High body fatne
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7.4.1 Trends, incidence, and surviv
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plasma or serum selenium; and 3 coh
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The Panel is aware that since the c
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— increased, notably in high-inco
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The evidence, though not copious an
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studies showed increased risk with
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elatively high in some countries in
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of being overweight or obese are ou
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mation caused by other factors (suc
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Box 7.8.1 Hepatitis viruses Hepatit
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ulates the body’s inflammatory re
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include mucinous carcinomas and ade
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There is a substantial amount of ev
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7.9.5.13 Cheese (Also see chapter 4
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cumference, or a 30 per cent increa
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The Panel judges as follows: The ev
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7.10.5.2 Lactation (Also see chapte
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The Panel is aware that since the c
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7.11 Ovary Ovarian cancer is the se
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nutrition, altered hormone profiles
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7.12.2 Pathogenesis Type 1 endometr
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case-control studies, and the mecha
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7.13.3 Other established causes (Al
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y environmental factors. Although s
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The evidence from cohort and case-c
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7.15 Kidney Cancer of the kidney is
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per 5 kg/m2 ; meta-analysis of case
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7.16.5 Evidence and judgements In t
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Despite the considerably higher inc
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7.18 Other cancers The Panel also c
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Tobacco use, infection with human T
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C H A P T E R 8 This chapter examin
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Box 8.1 Energy density A concept ce
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326 Table 8.2 Approximate relative
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food, using up oxygen in the proces
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Figure 8.4 Relationship between BMI
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density (box 8.1). Therefore, the P
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Table 8.5 Physical activity interve
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were 0.70 (95% CI 0.54-0.91; minima
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iours examined, including physical
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there was no statistically signific
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C H A P T E R 9 Cancer survivors Ca
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After recovery • People who are a
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Box 9.2 Use of supplements by cance
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C H A P T E R 1 0 348 P ART 2 • E
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other interested parties were exclu
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Milk and dairy products. One report
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adults, 16 30 35 36 40 41 44 46 56
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Table 10.1 Recommendations to preve
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10.6.3 Foods and drinks Cereals (gr
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CHAPTER 11 • RESEARCH ISSUES 11.1
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CHAPTER 11 • RESEARCH ISSUES Crit
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RECOMMENDATIONS PART 3 366 Introduc
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C H A P T E R 1 2 This Report is co
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12.1.4 Cancer in general This Repor
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12.1.7 Challenging The Panel emphas
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to enable them to increase their av
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Personal recommendations The points
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Guidance Most people can readily bu
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380 RECOMMENDATION 4 PLANT FOODS Ea
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382 RECOMMENDATION 5 ANIMAL FOODS L
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depending on the type of drink. Thi
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for a relatively long time in warm,
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388 SPECIAL RECOMMENDATION 1 BREAST
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ecommendations in this Report would
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ishing, and only the evidence on re
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���������� Appe
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APPENDIX A • PROJECT PROCESS canc
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APPENDIX B • THE FIRST WCRF/AICR
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APPENDIX C• THE WORLD CANCER RESE
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GLOSSARY Cantonese-style salted fis
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GLOSSARY Exposure A factor to which
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GLOSSARY Mineral An inorganic compo
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GLOSSARY Smoking (foods) Smoking is
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REFERENCES 41. Joint United Nations
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REFERENCES 18. Romney SL, Ho GY, Pa
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REFERENCES from postmenopausal wome
- Page 437 and 438:
REFERENCES 50. Black RJ, Bray F, Fe
- Page 439 and 440:
REFERENCES possible factor in the e
- Page 441 and 442:
REFERENCES 1992;69:860-5. 93. Su W,
- Page 443 and 444:
REFERENCES Causes Control 2004;15:6
- Page 445 and 446:
REFERENCES 292. Miller AB, Altenbur
- Page 447 and 448:
REFERENCES 386. Bosetti C, Negri E,
- Page 449 and 450:
REFERENCES [Correlation between nut
- Page 451 and 452:
REFERENCES cancer patients and heal
- Page 453 and 454:
REFERENCES Serum beta-carotene and
- Page 455 and 456:
REFERENCES Epidemiol 1991;1:385-93.
- Page 457 and 458:
REFERENCES and potential risk modif
- Page 459 and 460:
REFERENCES 1982;68:401-5. 134. Llop
- Page 461 and 462:
REFERENCES 225. Risch HA, Jain M, C
- Page 463 and 464:
REFERENCES Control 2003;14:1-12. 77
- Page 465 and 466:
REFERENCES 25. Pillow PC, Hursting
- Page 467 and 468:
REFERENCES factors and cancer incid
- Page 469 and 470:
REFERENCES al. A prospective study
- Page 471 and 472:
REFERENCES methylation and bladder
- Page 473 and 474:
REFERENCES southern Brazil: a case-
- Page 475 and 476:
REFERENCES 8. 59. Rao DN, Desai PB,
- Page 477 and 478:
REFERENCES [Alcoholism, smoking and
- Page 479 and 480:
REFERENCES vitamin D metabolites an
- Page 481 and 482:
REFERENCES alcohol consumption in p
- Page 483 and 484:
REFERENCES diseases. Hepatogastroen
- Page 485 and 486:
REFERENCES National Academy Press,
- Page 487 and 488:
REFERENCES Food patterns and risk o
- Page 489 and 490:
REFERENCES 35. Gerhardsson M, Norel
- Page 491 and 492:
REFERENCES endometrial cancer risk.
- Page 493 and 494:
REFERENCES 44. Batty GD, Shipley MJ
- Page 495 and 496:
REFERENCES Epidemiol Biomarkers Pre
- Page 497 and 498:
REFERENCES 225. Chie WC, Li CY, Hua
- Page 499 and 500:
REFERENCES folate intake and breast
- Page 501 and 502:
REFERENCES 413. Potischman N, Hoove
- Page 503 and 504:
REFERENCES The Netherlands. Eur J C
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REFERENCES 598. Leon DA, Lithell HO
- Page 507 and 508:
REFERENCES amenorrhoea: studies amo
- Page 509 and 510:
REFERENCES oropharyngeal squamous c
- Page 511 and 512:
REFERENCES 115. Cottam DR, Mattar S
- Page 513 and 514:
REFERENCES 2005;16:839-50. 207. Eng
- Page 515 and 516:
REFERENCES Renal cystic diseases: a
- Page 517 and 518:
REFERENCES predicting mortality amo
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REFERENCES 2006;48:1865-70. 155. Ki
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REFERENCES Chapter 9 1. Hewitt M, G
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REFERENCES Chapter 10 1. Cannon G.
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REFERENCES Council (Australia). 200
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INDEX classification, 214 colorecta
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INDEX weight gain determinants, 337
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INDEX Interleukin 6 (IL-6), 39 Inte
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INDEX adipose tissue-derived, 221 O
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INDEX stomach cancer, 146, 269-70 S
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INDEX trends, 324-7 Western diets,