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First results of the Phase II TITAN trial: anti-von Willebrand ... - Ablynx

First results of the Phase II TITAN trial: anti-von Willebrand ... - Ablynx

First results of the Phase II TITAN trial: anti-von Willebrand ... - Ablynx

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Rationale <strong>of</strong> TTP <strong>the</strong>rapy<br />

Congenital TTP Acquired TTP<br />

Supply ADAMTS13<br />

Remove <strong>the</strong> ULVWF<br />

and <strong>anti</strong>-ADAMTS13 Ab<br />

Supply ADAMTS13<br />

Plasma infusion PE<br />

Reduce<br />

<strong>anti</strong>-ADAMTS13 Ab<br />

production<br />

Steroids<br />

Immunosuppressives<br />

6

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