Brochure Minitube Semen Extenders
Brochure Minitube Semen Extenders
Brochure Minitube Semen Extenders
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Long Term<br />
<strong>Semen</strong><br />
<strong>Extenders</strong>
<strong>Minitube</strong> extenders are specifically<br />
formulated to replicate<br />
the natural qualities of seminal<br />
plasma by maintaining essential<br />
antioxidants, proteins<br />
and nutrients that are reduced<br />
when the semen is extended.<br />
Each ingredient serves a vital<br />
role by enhancing fertility,<br />
maintaining motility, supporting<br />
viability and facilitating<br />
sperm cell movement in the<br />
uterus.<br />
Engineered to Support Sperm Cells<br />
All <strong>Minitube</strong> long term extenders contain specific combinations of antioxidants,<br />
proteins, salts & sugars, buffering agents, antibiotics and proprietary compounds.<br />
Antioxidants are important molecules that slow or prevent oxidation, a<br />
biochemical process recognized as the major cause of sperm cell deterioration<br />
and death. Antioxidants are found naturally in seminal plasma and some have<br />
fertility enhancing properties. <strong>Minitube</strong> continuously researches the role of specific<br />
antioxidants in order to manufacture extenders with the most powerful and effective<br />
formulas available.<br />
Proteins are essential to living organisms and participate in almost every cell<br />
function. <strong>Minitube</strong> includes select proteins in highly complex extenders to boost cell<br />
performance.<br />
Salts & Sugars are necessary extender ingredients that maintain a healthy sperm<br />
cell environment. Salts maintain an isotonic solution that allows normal movement<br />
of water through the cell membrane. Sugars provide an energy source for the sperm<br />
cells during storage and are important for maintaining motility.<br />
HEPES Buffer is an organic buffering agent that is included in all <strong>Minitube</strong> long<br />
term extenders. Unlike extenders with simple buffering systems such as sodium<br />
bicarbonate and TRIS, HEPES automatically maintains a physiological pH level over a<br />
wide temperature range.<br />
Antibiotics help to control bacterial growth from contamination that occurs during<br />
collection through processing. <strong>Minitube</strong> provides antibiotic formulations that comply<br />
with national and international regulations.<br />
Cell Shield Plus (CSP) is a proprietary additive in <strong>Minitube</strong> Plus extenders which<br />
provides unparalleled protection for sperm cells when exposed to temperature<br />
fluctuations from 10˚C to 25˚C. CSP actively plays a role in membrane stabilization and<br />
protects against premature sperm cell capacitation. <strong>Minitube</strong> Plus extenders reduce<br />
adverse effects resulting from unpredictable environmental or handling conditions.
The Proven Gold Standard for Porcine AI<br />
• EnduraGuard & ApX 2 have proven to produce more piglets per<br />
litter, particularly when used as long term semen extenders.<br />
• EnduraGuard provides the most reliable solution for shipping<br />
fresh boar semen between the USA, Asia, or Europe and serves<br />
as a viable alternative to cryopreservation.<br />
• ApX 2 is the synthetic alternative which complies with the most<br />
stringent international shipping and import regulations.<br />
• Androstar offers the most cost effective performance of any<br />
synthetic boar semen extender.<br />
• Androhep Lite and Androhep Plus have proven their reliability<br />
and performance with more AI services than any other long<br />
term extender in the industry.<br />
• <strong>Minitube</strong>’s Plus extenders provide the best additional semen<br />
protection for the harshest and most variable storage and<br />
shipping conditions. Cell Shield Plus provides cold shock<br />
protection with the largest temperature range of any porcine<br />
semen extender.<br />
<strong>Minitube</strong> Offers a Full Range<br />
of Robust <strong>Extenders</strong><br />
Optimize Reproductive Performance<br />
Synthetic <strong>Extenders</strong><br />
<strong>Minitube</strong> has engineered animal protein free extenders using synthetic compounds as serum substitutes for the protection and<br />
stabilization of sperm cells. Synthetic extenders are important in order to meet certain international importation requirements. In<br />
addition, synthetic extenders can be used in swine production systems with specific hyper-stimulated immune system responses.<br />
Bovine Serum Albumin (BSA) Based <strong>Extenders</strong><br />
BSA is an animal derived serum protein with many functions. It binds and transports fatty acids, hormones and ions while maintaining<br />
osmotic pressure and pH. BSA binds free radicals to prevent lipid peroxidation, a reaction that causes alteration and damage to<br />
the cell membrane. These unique stabilizing and protective properties of BSA not only safeguard sperm cells against temperature<br />
fluctuation and mechanical stress, they minimize premature sperm capacitation that can occur during storage of semen. As a result,<br />
sperm capacitation takes place in a normal fashion inside the female reproductive tract. This approach ensures successful fertilization<br />
and optimization of reproductive performance.<br />
Storage<br />
Fertility<br />
<strong>Semen</strong> Storage<br />
Term<br />
Supportive Enhancing<br />
Temperature Range<br />
Product Name (days) BSA Synthetic Antioxidants Compounds** CSP Minimum Maximum<br />
Androstar 5 x x 16˚C 18˚C<br />
Androstar Plus 7 x x x x 10˚C 25˚C<br />
ApX2 10 x x x 16˚C 18˚C<br />
ApX2 Plus 10 x x x x 10˚C 25˚C<br />
Androhep Lite 5 x x 16˚C 18˚C<br />
Androhep Plus 7 x x x x 10˚C 25˚C<br />
EnduraGuard* 10 x x x 16˚C 18˚C<br />
EnduraGuard Plus* 10 x x x x 10˚C 25˚C<br />
* Patented formula containing a performance boosting protein that is exclusively offered by <strong>Minitube</strong><br />
** Based on statistically significant results in large scale trials
<strong>Minitube</strong> is committed to providing<br />
quality products that are tested<br />
for safety and proven to provide<br />
consistent top performance.<br />
Available Package Sizes<br />
1 Liter 100 Liter<br />
Androstar 13531/4001 13531/4100<br />
Androstar Plus 13531/3001 13531/3100<br />
ApX 2 13534/0100<br />
ApX 2 Plus 13534/3100<br />
Androhep Lite 13526/0001 13526/1100<br />
Androhep Plus 13527/1100<br />
EnduraGuard 13532/0001 13532/1100<br />
EnduraGuard Plus 13532/3100<br />
Antibiotic Customization<br />
All <strong>Minitube</strong> extenders are manufactured with effective antibiotics. Custom<br />
antibiotic combinations are available upon request.<br />
<strong>Minitube</strong> of America<br />
Phone: 800.646.4882<br />
usa@minitube.com<br />
<strong>Minitube</strong> Canada<br />
Phone: 800.500.7978<br />
canada@minitube.com<br />
<strong>Minitube</strong> Mexico<br />
Phone: 800.216.9282<br />
mexico@minitube.com<br />
www.minitube.com<br />
Comprehensive<br />
Quality Control<br />
Program<br />
Analytical QC<br />
All raw materials and final products<br />
undergo composition testing to<br />
ensure that performance and purity<br />
requirements are met. In addition,<br />
samples from each lot are retained<br />
for comparative analysis.<br />
Biological QC<br />
Each batch of semen extender is<br />
tested using boar semen for 125% of<br />
the indicated use period to ensure<br />
optimal performance.<br />
Production QC<br />
All <strong>Minitube</strong> extenders are manufactured<br />
in accordance with GMP<br />
guidelines within <strong>Minitube</strong>’s biosecure<br />
and USDA approved facility.
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