Documentation of published clinical trials and ... - Institut Hiscia

Quality of life / Pain 3.1
Buchner C. (1984) Über den Verbrauch von Analgetika und Psychopharmaka von Malignompatienten
mit und ohne adjuvante Misteltherapie. [On the use of analgesics and psychotropic
drugs in malignant neoplasm patients with and without mistletoe therapy.] Unpublished
manuscript, Stuttgart/Herdecke.
Study design
Design Retrospective study with 2 groups.
Patients 247 patients with malignant neoplasm, who were hospitalised in the
medical clinic of the town hospital, Stuttgart- Bad Cannstadt in the time
from 1970–1973. Most of the patients had advanced tumours; main
localisations were gastro-intestinal, urogenital or bronchial.
Treatment 123 patients received Iscador s.c. in various concentrations alongside the
usual oncological therapies (chemotherapy, radiotherapy, surgery). 124
patients did not receive Iscador.
Length of study 1970–1973.
Measurements Use of medication (analgesics, psychotropic drugs, spasmolitics etc.) during
the terminal phase of illness.
Most important results
The group of patients, who additionally received Iscador, required significantly less palliative
medication with medium and strong opiates, spasmolitics and tranquilisers during the terminal
phase of illness in comparison with the control group. The measurement of medication dose did
not occur in mg per period of time, but in very rough groups. The Iscador group generally
showed a small disadvantage when regarding prognosis factors (distribution of stages of disease,
age and forms of additional therapy). The mean survival in the Iscador group was 11.3 months
longer than the control group (not significant).
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