Documentation of published clinical trials and ... - Institut Hiscia

Quality of Life / Pain 3.3
Hajto T., Hostanska K., Fornalski M., Kirsch A. (1992) Eine neue Alternative zur Erhöhung der
antitumoralen Wirkung eines klinisch angewandten Mistelextraktes durch Lektin-Optimierung.
[A new alternative to increase the antitumoural effect of clinically applied mistletoe extract using
lectin optimisation.] Erfahrungsheilkunde 41 (6), 406–408.
Study design
Design Prospective, non-controlled study.
Patients 16 tumour patients (breast, liver, bladder, colon, tongue, prostate cancer,
malignant melanoma and sarcoma) at stage III or IV.
Treatment Iscador “dose optimised” (dose equivalent of 1ng mistletoe lectin / kg
bodyweight), 2 times a week during 5 to 12 months. 12 patients received
only Iscador therapy, without the other therapy modality
Length of study 1989–1991.
Measurements Karnofsky Index, tumour remission.
Most important results
Quality of life improved in 14 of the 16 patients. The Karnofsky Index improved on average
from 70 to 87 after treatment. The study was not evaluated statistically.
Quality of Life Idex
before therapy with Iscador after approx. 7 months of Iscador
Fig. 1: The patients’ quality of life was ascertained using the Karnofsky
Index before and after, on average, 7 months of treatment. The points
show the individual measurement values and the bars show the mean
values (graph according to Hajto et al. 1992).
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