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MIND-BLOWING BRAINS How research helps us look inside the brain

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The <strong>brain</strong> is one of our<br />

most fascinating organs.<br />

Developments in technology<br />

and medicine mean that<br />

doctors and scientists can<br />

examine our <strong>brain</strong>s in more<br />

ways and more detail than<br />

ever before, all without<br />

having to open up <strong>the</strong> body.<br />

Join <strong>us</strong> as we find out more<br />

about how imaging <strong>research</strong><br />

has changed <strong>the</strong> way we can<br />

<strong>look</strong> <strong>inside</strong> <strong>the</strong> human <strong>brain</strong>.<br />

INSIDE<br />

NEURONS By NUMBERS<br />

A numerical tour of <strong>brain</strong>s<br />

and <strong>brain</strong> imaging.<br />

Why ThE BRAIN?<br />

Exploring <strong>the</strong> basics of <strong>brain</strong><br />

structure and function.<br />

STRUCTURAL IMAGING<br />

<strong>How</strong> <strong>research</strong>ers and clinicians<br />

can see <strong>inside</strong> our <strong>brain</strong>s.<br />

FUNCTIONAL IMAGING<br />

Ways to study what is happening<br />

in <strong>the</strong> <strong>brain</strong>.<br />

MyThBUSTING<br />

Putting to rest some common<br />

<strong>brain</strong>y misconceptions.<br />

KNOW yOUR <strong>MIND</strong><br />

Looking at some social, ethical<br />

and legal issues to do with <strong>the</strong> <strong>brain</strong>.<br />

REAL vOICES<br />

Three people talk about <strong>the</strong><br />

role of <strong>brain</strong>s in <strong>the</strong>ir lives.<br />

ONLINE<br />

2 | BIG PICTURE 17: INSIDE THE bRAIN<br />

2<br />

4<br />

6<br />

8<br />

10<br />

12<br />

14<br />

Go to www.wellcome.ac.uk/bigpicture/<br />

<strong>brain</strong> for more teaching resources, including<br />

extra articles, videos, image galleries,<br />

curriculum links, lesson ideas, a poster and<br />

an animation of <strong>the</strong> action potential. You can<br />

also download <strong>the</strong> PDF of this magazine or<br />

subscribe to <strong>the</strong> Big Picture series.<br />

Neurons by numbers<br />

The vital stats of <strong>brain</strong>s and <strong>brain</strong> imaging<br />

AvERAGE hUMAN BRAIN vOLUME<br />

1.5 l<br />

1.0 l<br />

0.5 l<br />

0.0 l<br />

Source: www.ncbi.nlm.nih.gov/pmc/articles/PMC2711771/<br />

BRAIN SIzE AND MASS<br />

Relative <strong>brain</strong> size and<br />

shape viewed from top<br />

1.13 l<br />

Elephant<br />

Human<br />

Chimp<br />

0.42 kg<br />

1.26 l<br />

1.4 kg 4.8 kg<br />

Sources: faculty.washington.edu/chudler/facts.html, www.frontiersin.org/neuroanatomy/10.3389/fnana.2011.00029/full<br />

TOTAL NUMBER OF SyNAPSES IN hUMAN NEOCORTEx<br />

150 000 00<br />

The neocortex is a six-layered part of <strong>the</strong> cerebral cortex found in mammals.<br />

Source: postcog.ucd.ie/files/Pakkenberg%202003.pdf

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