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Complications of ventilation tubes: - Dr. Nassem Talaat

Complications of ventilation tubes: - Dr. Nassem Talaat

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3) Moniliasis (oral thruth)<br />

Def: Acute specific inflammation <strong>of</strong> pharynx & oral cavity<br />

Aet : Organism: candida albicans Predisposing factors …..<br />

Symptons : Sore throat & dysphagia , no fever<br />

Signs: Milky white raised patches<br />

Treatment: - Stop antibiotics, adequate nutrition<br />

C) Blood diseases<br />

- Topical antifungal: mycostation , daktarin gel .<br />

-Systemic antifungal in severe cases e.q ketoconazole.<br />

1) Acute leukaemia neoplastic proliferation <strong>of</strong> the precursors <strong>of</strong> WBCS leading to<br />

- Anemia: fatigue pallor.<br />

- Thrombocytopenia : purpura , epistaxis, and bleeding tendency<br />

- Intercurrent infection : fever & sore throat, ulcers & membrane over the tonsils<br />

swollen purpulish gingiva & easy bleeding<br />

- Lymphadenopathy , splenomgaly - Sternal tenderness<br />

Investigations: 1- CBC 2- B.M aspiration<br />

Treatment: Cytotoxic drugs.<br />

2) Agrunulocytosis<br />

Def: marked reduction in formation <strong>of</strong> PNLs<br />

Aet : B.M depression, 1ry or 2ry to drugs (antibiotics: chloramphenicol,<br />

antimetabolites: methotrexate) or radiation.<br />

Clinical picture<br />

- Fever , malaise , rapid deterioration <strong>of</strong> general condition<br />

- Extensive ulceration with no or little surrounding inflammatory reaction<br />

Investigations: 1- CBC 2- MB aspiration<br />

Treatment :<br />

1- Stop <strong>of</strong>fending drug 2- Isolation<br />

3-Antibiotics & blood transfusion 4-B.M transplant

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