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LYMPHATIC SYSTEM consists of: 1. lymph capillaries 2. collecting ...

LYMPHATIC SYSTEM consists of: 1. lymph capillaries 2. collecting ...

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LYMPH ORGANS<br />

THYMUS<br />

<strong>lymph</strong>oid organ and endocrine gland<br />

main function:<br />

- differentiation <strong>of</strong> <strong>lymph</strong>ocytes into the different classes<br />

- production <strong>of</strong> various factors and hormones which regulate <strong>lymph</strong>ocytes production,<br />

differentiation and activities within the thymus, peripheral <strong>lymph</strong>oid tissue and<br />

elsewhere<br />

located in the anterior mediastinum<br />

extends into the neck<br />

may reach lower part <strong>of</strong> thyroid gland (in children)<br />

relations:<br />

anteriorly – sternum and costal cartilages<br />

- infrahyoid muscles<br />

posteriorly – heart in pericardium<br />

- brachicephalic veins and sup. v. cava<br />

- aortic arch and its branches<br />

- trachea<br />

laterally – pleurae and lungs<br />

varies in size with age<br />

at birth: 10 – 15 gm<br />

grows up to the puberty: 30 – 40 gm<br />

progressively diminishes – atrophy, replacement by fat<br />

mid-adult life: 10 gm<br />

childhood<br />

pinkish-grey in colour<br />

lobulated<br />

right and left lobes connected by fibroareolar tissue<br />

Structure:<br />

fibrous capsule<br />

septa → lobules<br />

lobule – cortex, medulla (fewer <strong>lymph</strong>ocytes than the cortex)<br />

Blood supply:<br />

arteries<br />

Thymic branches <strong>of</strong> inf. thyroid a. and int. thoracic a.<br />

Veins – drained into the inf. thyroid, brachiocephalic and<br />

int. thoracic veins<br />

Nerve supply: sympathetic nerves – cervicothoracic ganglion<br />

parasympathetic fibres (vagus n.)<br />

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