Production of Bioactives by Intestinal bacteria:

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Intraspecies Diversity: Lactobacillus salivarius 6027 6502 6189 6005 118 6196 7.3 6488
Salivaricin P, 13 kb Natural Variants from Gut Strains AP118 ORF 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Sln1 Sln2 SlnIM SlnIP SlnK SlnR SlnT SlnD <strong>Production</strong>/ immunity Regulation Transport UCC118 KNGYGGSGNRWVHCGAGIVGGALIGAIGGPWSAVAGGISGGFTSCR DPC6196 KNGYGGSGNRWVHCGAGIVGGALIGTIGGPWSAVAGGISGGFISCR DPC6005 KNGYGGSGNRWVHCGAGIVGGALIGAIGGPWSAVAGGISGGFASCH
Page 1 and 2: Production of Bioactives by Intesti
Page 3 and 4: 1. Bacteriocin production Productio
Page 5 and 6: 1. Bacteriocin production Productio
Page 7 and 8: Class 2 Mode of Action Lipid II Cla
Page 9 and 10: Corr S. C. et.al. PNAS 2007;104:761
Page 11 and 12: 11.6kg Control 11.7kg Probiotic 1 (
Page 13: Mean Live5 count in ileum = 1.3 x 1
Page 17 and 18: Abp118 is encoded on megaplasmid pM
Page 19 and 20: Salivaricin T genes 4433.90 Da 5655
Page 21 and 22: Microbial Production of Bioactives
Page 23: Mary Rea Bacillus thuringiensis Rea
Page 26 and 27: Thuricin contains unusual post-tran
Page 28 and 29: ! # s s s "# s s s Rea et al. PNAS
Page 30 and 31: C. diff log 8 7 6 5 4 3 Faecal ferm
Page 32 and 33: Microbial Production of Bioactives
Page 34 and 35: • Gut microbiota proposed to exer
Page 36 and 37: % Conversion to CLA 90 80 70 60 50
Page 38 and 39: *** LA + B. breve LA BALB/c mice SC
Page 40 and 41: Compositional change is not limited
Page 42 and 43: Increased DHA content of brain foll
Page 44 and 45: Conclusions • Gut flora/probiotic
Page 47 and 48: Trn-! Trn-! T 0h T 5h Trn-! and ! t

Production of Bioactives by Intestinal bacteria:

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