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ORAL' MANIFESTATIONS IN SYSTEMIC DISEASES ...

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H. H. STONES<br />

observed during the three years commencing in 1942. Most observers<br />

have been unable to establish any correlation between low plasma levels<br />

of ascorbic acid and the more frequent type of gingivitis (Restarski and<br />

Pijoan, 1944).<br />

It may happen that a patient is suffering from a deficiency of more<br />

than one of the vitamin components and in this case the clinical features<br />

of the various deficiencies may occur together; as already mentioned<br />

this particularly happens in connection with the vitamin B complex and<br />

may also occur with vitamins B and C. Further, and particularly in<br />

nutritionally neglected old and middle aged cases, there may be an<br />

anaemia in which the blood picture shows a marked reduction both in<br />

the haemoglobin and red cell count.<br />

Hence these possibilities must be evaluated when instituting treatment<br />

and any suspected deficiency including that of iron must be covered.<br />

THE ORAL <strong>MANIFESTATIONS</strong> OF THE BLOOD DYSCRASIAS<br />

In the blood dyscrasias a variety of oral manifestations may be<br />

produced depending on the particular disease. As will be seen, in some<br />

conditions they are but slight and in others severe. It is very important<br />

for the dental practitioner to recognise the signs as he may be in a<br />

position to be the first to examine a patient with a serious or fatal<br />

disease, or sometimes if he operates without appreciating its significance,<br />

the patient may be subjected to a dangerous risk. It is proposed to<br />

mention representative types that illustrate the effect on the oral mucosa.<br />

The aetiology and haematology are reviewed by Sturgis (1948) and<br />

Whitby and Britton (1950).<br />

Hypochromic Anaemia<br />

Idiopathic hypochromic anaemia.-This usually occurs in young and<br />

adult women and is caused by a deficient absorption of iron, which is<br />

frequently associated with the hypochlorhydria that so often accompanies<br />

the condition.<br />

The blood picture usually shows that the red cell count is somewhat<br />

reduced and red blood corpuscles are smaller than normal. The colour<br />

index is low, being about 0 5 to 0 6 while the haemoglobin is reduced<br />

to 40 per cent. or 50 per cent.<br />

The oral mucosa is pale and there is a tendency to bleed from the<br />

gingivae. The tongue is occasionally smooth due to atrophy of the<br />

filiform papillae, and sometimes shows indentations from the teeth.<br />

The general symptoms include pallor, breathlessness and palpitation.<br />

There may be koilonychia, that is atrophic, thin and spoon-shaped nails.<br />

The condition improves following the oral administration of iron<br />

preparations.<br />

Plummer-Vinson Syndrome.-This condition usually occurs in middle<br />

aged females. It is associated with hypochromic anaemia and sometimes<br />

with hypochlorhydria. There may be an associated vitamin B complex<br />

deficiency.<br />

238

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