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PANSERIN TM 604<br />

PANSERIN TM 604 is a complete medium ready for use for the cultivation of transfected and<br />

non-transfacted CHO-cells (Chinese Hamster Ovary).<br />

These cells are frequently used for the production of recombinant proteins. The cells normally grow<br />

adherently (e.g. in roller cultures), however with suitable media and with the optimal media they<br />

can also be kept in suspension culture (continuous perfusion or batch systems).<br />

PAN-Biotech has developed an optimal version for every application:<br />

For the suspension culture:<br />

• PANSERIN TM 604ST serumfree – optimal cell growth, quick adaption<br />

• PANSERIN TM 604S without protein or peptide components of animal or human origin<br />

• PANSERIN TM 604SPF chemically defined, proteinfree<br />

The following graph shows the growth curves of the PANSERIN TM 604 versions.<br />

The CHO-cells were cultivated from an adherent culture containing serum in PANSERIN TM 604<br />

without a preceding adaption. The seed amounted to 50 000 cells/ml. The maximum generation<br />

times were 15,3 to 18,5 hours.<br />

Composition:<br />

PANSERIN TM 604 serumfree:<br />

A basal medium optimized for suspension cultures, which had been designed for a high cell density,<br />

was supplemented with hormons, lipids and special growth factors for an optimal growth of CHOcells.<br />

It does not contain any undefined lysates or plant hydrolysates. It allows a very quick growth<br />

of the cells without long adaption phases.<br />

BIOTECH GmbH<br />

<br />

The company<br />

Am Gewerbepark 13, D-94501 Aidenbach<br />

phone +49 (0) 85 43 - 60 16-30, fax +49 (0) 85 43 - 60 16-49<br />

e-mail: info@pan-biotech.de, http://www.pan-biotech.de<br />

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