CURRICULUM VITAE RAMON ERITJA, Ph. D. Birth date ... - IS3NA

RAMON ERITJA, Ph. D.
CURRICULUM VITAE
Birth date: August 9, 1955
Birthplace: Lleida, Spain
Nationality: Spanish
Address: Tarragona 106, 1, 1.E-08015 Barcelona, Spain.
Telephone: 0034-93-5393736
ACTUAL POSITION
Profesor de Investigación CSIC (equivalent to Full Professor)
Institute for Advanced Chemistry of Catalonia
Centro de Investigación y Desarrollo
Consejo Superior de Investigaciones Científicas (CSIC)
Address: Jordi Girona 18-26. E-08034 Barcelona, Spain
Telephone: 0034-93-4006145
Fax number: 0034-93-2045904
Email: recgma@cid.csic.es
The group has been accepted in the Institut for Biomedical Research.
Institut de Recerca Biomedica (IRB)
Parc Científic de Barcelona (PCB)
Address: Baldiri Reixac 12. E-08028 Barcelona, Spain
Telephone: 0034-93-4039941 and 0034-93-4039942
Email: ramon.eritja@irbbarcelona.org
GRADUATE STUDIES
1972-1977: B.Sc. (Chemistry), Faculty of Chemistry, University of Barcelona, Spain.
1977-1982: B.Sc. (Pharmacy), Faculty of Pharmacy, University of Barcelona, Spain.
1983: Ph.D. (Chemistry), Faculty of Chemistry, University of Barcelona, Spain.
RESEARCH AND TEACHING EXPERIENCE
1999-actual: Group Leader. Consejo Superior de Investigaciones Científicas. Barcelona, Spain.
1994- 1999: Group Leader. European Molecular Biology Laboratory. Heidelberg, Germany.
1989-1994: Research Associate-Group Leader. Center for the Research and Development.
C.S.I.C. Barcelona. Spain.

1987-1989: Postdoctoral Fellow. Department of Organic Chemistry. University of Barcelona.
Barcelona, Spain.
1986-1987: Research Associate. Department of Chemistry and Biochemistry. University of
Colorado, Boulder. Boulder, Colorado.
1984-1986: Postdoctoral Fellow. Department of Molecular Genetics. Beckman Research
Institute of the City of Hope. Duarte, California. Head of the Department: Dr. K. Itakura.
1978-1984: Teaching Assistant of practical works of Organic Chemistry. Faculty of Chemistry.
University of Barcelona. Head of Department: Dr. J. Castells.
1977-1984: Graduate student with Dr. E. Giralt and Dr. E. Pedroso. Department of Organic
Chemistry. Faculty of Chemistry. University of Barcelona. Spain.
October 1981, April 1982, November 1982 and February 1983: Laboratoire de Biochemie,
Faculty of Medicine, University of Aix-Marseille, France. Head of Department: Dr. F. Miranda.
HONORS
1972 - 1977 : Fellowship of Education Ministry, Spain.
1981 : Fellowship of Foreign Office, France.
1984-1986: Postdoctoral fellowship from Fundación Juan March, Spain.
1989 : Member of the European Peptide Society
1989 : Member of the American Peptide Society
1990 : Member of the International Society of Nucleic Acid Chemistry.
Ph.D. THESIS SUPERVISED.
1987-90. Dolors Fernández Forner. Faculty of Chemistry. U. of Barcelona.
1989-93. Beatriz Garcia de la Torre. Faculty of Chemistry. U. of Barcelona.
1990-94. Mónica Escarceller Comes. Faculty of Biology. U. of Barcelona..
1992-95. Montse Acedo Almagro. Faculty of Chemistry. U. of Barcelona.
1992-95. Anna Aviñó Andrés. Faculty of Chemistry. U. of Barcelona.
1993-96. Gemma Tarrasón Encuentra. . Faculty of Biology. U. of Barcelona.
1993-97. Carme Fàbrega Clavería. . Faculty of Chemistry. U. of Barcelona.
1994-97. Morten Grøtli. Faculty of Chemistry. U. of Oslo.
1995-99: Elisenda Ferrer Oliveras. Faculty of Chemistry. U. of Barcelona.
1997-2001. Ramon Güimil García. Faculty of Sciences. UNED. Spain.
2002-2006. Marta Gutiérrez Grimau. Faculty of Chemistry. U. of Barcelona
2005-2010. Brendan Manning. School of Chemistry and Chemical Biology. UCD, Dublín.
2005-2010. Sandra Milena Ocampo. Faculty of Medicine. U. de Barcelona.
2006-2010. Margarita Alvira Torre. Faculty of Chemistry. U. de Barcelona.
TESINA (equivalent to Master Thesis) SUPERVISED

1990. Yolanda Palom Monreal. Faculty of Chemistry. U. of Barcelona.
1990. Anna Pons Sauné. Faculty of Biology. U. of Barcelona.
1990. Mónica Escarceller Comes. Faculty of Biology. U. of Barcelona.
1991. Jordi Robles Brau. Faculty of Chemistry. U. of Barcelona.
1992. Ana Maria Avinó Andrés. Faculty of Chemistry. U. of Barcelona.
1992. Montse Acedo Almagro. Faculty of Chemistry. U. of Barcelona.
1993. M Carme Fàbrega Clavería. Faculty of Chemistry. U. of Barcelona.
1993. Angeles Cano López. Faculty of Chemistry. U. of Barcelona.
1993. Montse Aparicio Manau. Master Interuniversitari de Biotecnología. U. de Barcelona.
1996. Elisenda Ferrer Oliveras. Faculty of Chemistry. U. of Barcelona.
1997. Dirk Gottschling (Diplomarbeit). Department of Polymer Science. U. de Ulm.
2002. Marta Gutiérrez Grimau. Faculty of Chemistry. U. of Barcelona.
2006. Sandra Milena Ocampo. Dpt. of Pharmacology. U. Autónoma de Barcelona.
2007. Roger Ramos Ballespí. Faculty of Chemistry. U. of Barcelona.
PUBLICATIONS IN SCIENTIFIC JOURNALS
"Synthesis of Nbb-resin, a new polymer support for the solid phase synthesis of protected
peptides."
Giralt, E., Albericio F., Andreu D., Eritja R., Martin P., Pedroso E.
An. Quim. 77C, 120-125 (1981).
"Diketopiperazine formation in acetamido- and nitrobenzamido-bridge polymeric supports.
Giralt, E., Eritja, R., Pedroso, E.
Tetrahedron Lett. 3779-3782 (1981).
"Amino-acids condensations in the preparation of N-9-fluorenyl methoxycarbonylamino-acids
with 9-fluorenylmethyl chloroformate."
Tessier, M., Albericio, F., Pedroso, E., Grandas, A., Eritja, R., Giralt, E., Granier, C., Van
Reitschoten, J.
Int. J. Peptide Protein Res. 22, 125-128 (1983).
"On the use of an O-cyclohexyl ether for protection of tyrosine in peptide synthesis."
Giralt, E., Andreu, D., Eritja, R., Grandas, A., Pedroso, E.
An. Quim. 79C, 390-391 (1983).
"Solid phase synthesis of antamanide on a nitrobenzamidobenzyl polystyrene support.
Giralt, E., Eritja, R., Navalpotro, C., Pedroso, E.
An. Quim. 80C, 118-122 (1984).
"Use of Nbb-resin in cyclic dipeptide (diketopiperazine) synthesis."
Giralt, E., Eritja, R., Josa, J., Kuklinski, C., Pedroso, E.
Synthesis 181-184 (1985).

"Convergent solid phase peptide synthesis III. Synthesis of the 44-52 protected segment of the
toxin II of Androctonus australis Hector."
Giralt, E., Eritja, R., Pedroso, E., Granier, C., Van Rietschoten, J.
Tetrahedron 42, 691-698 (1986).
"Diketopiperazine formation in solid phase peptide synthesis using p- alkoxybenzyl ester resins
and Fmoc-amino acids."
Pedroso, E., Grandas, A., de las Heras, X., Eritja, R., Giralt, E.
Tetrahedron Letters 743-746 (1986).
"Base pairing and mutagenesis: Observation of a protonated base pair between 2- aminopurine
and cytosine in an oligonucleotide by proton NMR."
Sowers, L.C., Fazakerley, G.V., Eritja, R., Kaplan, B.E., Goodman, M.F.
Proc. Natl. Acad. Sci. USA 83, 5434-5438 (1986).
"Synthesis and characterization of defined oligomers containing 2-aminopurine."
Eritja, R., Kaplan, B.E., Mhaskar, D., Sowers, L.C., Petruska, J., Goodman, M.F.
Nucleic Acids Res., 14, 5869-5884, 1986.
"Conformational behaviour of nucleotides relevant to DNA replication fidelity."
Goodman, M.F., Petruska, J., Sowers, L.C., Boosalis, M., Randall, S.K. Dalton, L., Mhaskar,
D.N., Khwaja, T., Fazakerley, G.V. , Eritja, R., Kaplan, B.E.
J. Cell. and Biochem. Suppl. 10B, 231 (1986).
"Synthesis and properties of oligonucleotides containing 2'-deoxynebularine and 2'deoxyxanthosine."
Eritja, R., Horowitz, D.M., Walker, P.A., J. Paige Ziehler-Martin, Boosalis, M.S., Goodman,
M.F., Itakura, K., Kaplan, B.E.
Nucleic Acids Res., 14, 8135-8153, (1986).
"Synthesis of oligonucleotides containing the abasic site model compound 1,4- anhydro-2-deoxy-
D-ribitol."
Eritja, R., Walker, P.A., Randall, S.K., Goodman, M.F., Kaplan, B.E.
Nucleotides and Nucleosides 6, 803-814, (1987).
"On the use of S-t-butylsulphenyl group for protection of cysteine in solid-phse peptide synthesis
using Fmoc-amino acids."
Eritja, R., Ziehler-Martin, J.P., Walker, P.A., Lee, T.D., Legesse, K., Albericio, F., Kaplan, B.
Tetrahedron 43, 2675-2680, (1987).
"NMR studies on oligo-deoxynucleotides containing 2-aminopurine opposite adenine and
guanine."
Fazakerley, G.V., Sowers, L.C., Eritja, R., Kaplan, B.E., Goodman, M.F.
Biochemistry 26, 5641-5646, (1987).
"NMR Studies of the stable mismatch purine.thymine in the self-complementary
d(CGPuAATTTCG) duplex in solution."

Ikuta, S., Eritja, R., Kaplan, B.E., Itakura, K.
Biochemistry 26, 5646-5650, (1987).
"Nucleotide insertion kinetics opposite abasic lesions in DNA."
Randall, S.K., Eritja, R., Kaplan, B.E., Petruska, J., Goodman, M.F.
J. Biol. Chem., 262, 6864-6870, (1987).
"Inhibition of human immunodeficiency virus (HIV) using an oligonucleoside
methylphosphonate"
Zaia, J.A., Cantin, E., Rossi, J.J., Spallone, P.A, Murakawa, G., Eritja, R., Kaplan, B., Wallace,
R.B.
J. Cell. Biochem. 72 Suppl., 11D (1987).
"An abasic site in DNA. Solution conformation determined by proton NMR and molecular
mechanics calculations."
Cuniasse, Ph., Sowers, L.C., Eritja, R., Kaplan, B., Goodman, M.F., Cognet, J.A.H., LeBret, M.,
Guschlbauer, W., Fazakerley, G.V.
Nucleic Acids Res., 15, 8003-8022, (1987).
"Structural and dynamic properties of a bromouracil-adenine base pair in DNA studied by proton
NMR."
Fazakerley, G.V., Sowers, L.C., Eritja R., Kaplan, B.E., Goodman, M.F.
J. Biomolecular Structure and Dynamics 5, 639-650 (1987).
"Structural and dynamic properties of a fluorouracil-adenine base pair in DNA studied by proton
NMR."
Sowers, L.C., Eritja, R., Kaplan, B.E., Goodman, M.F., Fazakerley, G.V.
J. of Biol. Chem. 262, 15436-15442 (1987).
"Inhibition of human immunodeficiency virus (HIV) using an oligonucleoside
methylphosphonate targeted to the TAT-3 gene."
Zaia, J.A., Rossi, J.J., Murakawa, G.J., Spallone, P.A., Stephens, D.A., Kaplan, B., Eritja, R.,
Wallace, R.B., Cantin, E.M.
J. Virol. 62, 3914-3917 (1988).
"Equilibrium between a wobble and ionized base pair formed between fluorouracil and guanine
in DNA as studied by proton and fluorine NMR."
Sowers, L.C., Eritja R., Kaplan, B.E., Goodman, M.F., Fazakerley, G.V.
J. Biol. Chem. 263, 14794-14801 (1988).
"Purification and Characterization of an inducible Escherichia coli DNA polymerase capable of
insertion and bypass at abasic lesions in DNA."
Bonner, C.A., Randall, S.K., Rayssigguier, Ch., Radman, M., Eritja, R., Kaplan, B.E., McEntee,
K., Goodman, M.F.
J. of Biol. Chem. 263, 18946-18952 (1988).

"Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological
conditions."
Sowers, L.C., Goodman, M.F., Eritja, R., Kaplan, B., Fazakerley, G.V.
J. Mol. Biol. 205, 437-447 (1989).
"Abasic frameshift in DNA. Solution conformation determined by proton NMR and molecular
mechanics calculations."
Cuniasse, Ph., Sowers, L.C., Eritja, R., Kaplan, B.E., Goodman, M.F., Cognet, J.A.M., LeBret,
M., Guschlbauer, W., Fazakerley, G.A.
Biochemistry 28, 2018-2026 (1989).
"Characterization of the high pH wobble structure of the 2-aminopurine.cytosine mismatch by N-
15 NMR spectroscopy."
Sowers, L.C., Eritja, R., Chen, F. Ch., Khwaja, T., Kaplan, B.E., Goodman, M.F., Fazakerley,
G.V.
Biochem. Biophys. Res. Comm. 165, 89-92 (1989)
"Estudio de la detección de oligonucleótidos marcados con compuestos fluorescentes utilizando
la quimioluminiscencia de los ésteres del ácido oxálico."
Eritja, R., Johnson, D., Ziehler-Martin, P., Walker, P.A., Kaplan, B.E.
An. Quim. 85C, 80-84 (1989).
“On the use of polystyrene as a solid support in oligodeoxynucleotide synthesis.”
Pedroso, E., Bardella, F., Eritja, R., Giralt, E.
Reactive Polymers 10, 309-310 (1989).
"O-Aryl phosphoramidites: Synthesis, reactivity and evaluation of their use for solid-phase
synthesis of oligonucleotides."
Eritja, R., Smirnov, V., Caruthers, M.H.
Tetrahedron 46, 721-739 (1990).
"Gel-phase NMR spectroscopy a useful tool in Solid Phase Synthesis."
Giralt, E., Albericio, F., Bardella, F., Eritja, R., Feliz, M. Pedroso, E., Pons, M., Rizo, J.
Innovation and Perspectives in Solid Phase Synthesis pp 111-120 (1990) SPCC Ltd (Inglaterra).
"Synthesis and characterization of oligonucleotides containing the mutagenic base analogue 4-Oethylthymidine."
Fernandez-Forner, D., Palom, Y., Ikuta, S., Pedroso, E., Eritja, R.
Nucleic Acids Res. 18, 5729-5734 (1990).
"NPE-resin, a new approach for the solid-phase synthesis of protected peptides and
oligonucleotides. I Synthesis of the supports and their application to oligonucleotide synthesis."
Eritja, R., Robles, J., Fernandez-Forner, D., Albericio, F., Giralt, E., Pedroso, E.
Tetrahedron Lett. 32, 1511- 1514 (1990).
"NPE-resin, a new approach for the solid-phase synthesis of protected peptides and
oligonucleotides. II Synthesis of protected peptides."

Albericio, F., Giralt, E., Eritja, R.
Tetrahedron Lett. 32, 1515- 1518 (1990).
"Synthesis of oligonucleotides containing 4-O-ethylthymidine."
Pedroso, E., Fernandez, D., Palom, Y., Eritja, R.
Nucleosides and Nucleotides 10, 623 -624 (1991).
"Synthesis of defined peptide-oligonucleotide hybrids containing a nuclear transport signal
sequence."
Eritja, R., Pons, A., Escarceller, M., Giralt, E., Albericio, F.
Tetrahedron 47, 4113- 4120 (1991).
"NPE-resin : a new approach for the synthesis of protected peptides and oligonucleotides."
Albericio, F., Robles, J., Fernandez, D., Palom, Y., Celma, C., Pedroso, E., Giralt, E., Eritja, R.
Peptides 1990. Proc. of the 21th European Peptide Symposium. ESCOM pp 134-136 (1991).
"Biopolymer syntheses on novel polyethylene glycol-polystyrene (PEG-PS) graft supports."
Barany, G., Albericio, F., Biancalana, S., Bontems, S., Chang, J., Eritja, R., Ferrer, M., Fields,
C., Fields, G., Lyttle, M., Solé, N, Tian, Z., Van Abel, R., Wright, P., Zalipsky, S., Hudson, D.
Peptides, Chemistry and Biology (Smith, J.A., Rivier, J. Eds), 1992, Escom Ltd (Leiden) pp 603-
604.
"Convergent solid-phase peptide synthesis."
Albericio, F., Lloyd, P., Gairi, M., Jou, G., Eritja, R., Giralt, E.
Peptides, Chemistry and Biology (Smith, J.A., Rivier, J. Eds) 1992, Escom Ltd (Leiden) pp 607-
609.
"Cysteine protection in solid phase peptide synthesis."
Royo, M., Garcia, C., Munson, M., Slomczynska, Eritja, R., Giralt, E., Barany, G., Albericio, F.
Innovation and Perspectives on Solid Phase Peptide Synthesis, (Epton R. Ed.), 1992, Intercept
Ltd (Andover) pp 461-465.
"Convergent Solid Phase Peptide Synthesis."
Albericio, F., Lloyd, P., Gairi, M., Jou, G., Celma, C., Kneib-Cordonier, N., Grandas, A., Eritja,
R., Pedroso, E., Van Rietschoten, J., Barany, G., Giralt, E.
Innovation and Perspectives on Solid Phase Peptide Synthesis, (Epton R. Ed.), 1992, Intercept
Ltd (Andover) pp 39-47.
"Phosphorylation of maize RAB-17 protein by casein kinase 2."
Plana, M., Itarte, E., Eritja, R., Goday, A., Pagès, M., Martinez, M.C.
J. of Biol. Chem. 266, 22510-22514, (1991).
"Preparation of oligonucleotides containing dAICA using an unexpected side-reaction observed
on a protected derivative of 2-aza-2'-deoxyinosine."
Fernandez-Forner, D., Eritja, R., Bardella, F., Ruiz-Perez, C., Solans, X., Giralt, E., Pedroso, E.
Tetrahedron 47, 8917-8930, (1991).

"Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accesory
proteins."
Bonner, C. A., Stukenberg, P.T., Rajagopalan, M., Eritja, R., O'Donnell, M., McEntee, K.,
Echols, H., Goodman, M.F.
J. of Biol. Chem. 267, 11431-11438, (1992).
"S-2-(2,4-dinitrophenyl)ethyl-L-cysteine: a new derivative for solid-phase peptide synthesis."
Royo, M., García-Echevarría, C., Giralt, E., Eritja, R., Albericio, F.
Tetrahedron Lett. 33, 2391-2394, (1992).
"A synthetic procedure for the preparation of oligonucleotides without using ammonia and its
application for the synthesis of oligonucleotides containing O-4-alkyl thymidines."
Eritja, R., Robles, J., Aviñó, A., Albericio, F., Pedroso, E.
Tetrahedron 48, 4171-4182, (1992).
"N-2-(2,4-dinitrophenyl)ethoxycarbonyl amino acids, new base labile protected derivatives
suitable for solid-phase peptide synthesis."
Acedo, M., Albericio, F., Eritja, R.
Tetrahedron Lett. 33, 4989-4992, (1992).
"Detection of Hepatitis B virus in human serum samples: Use of digoxigenin-labeled
oligonucleotides as modified primers for the Polymerase Chain Reaction."
Escarceller, M., Rodriguez-Frias, F., Jardi, R., San Segundo, B., Eritja, R.
Anal. Biochem. 206, 36-42 (1992).
"Ionization of Bromouracil and fluorouracil stimulates base pairing frequencies with guanine."
Yu, H., Eritja, R. , Bloom, L. and Goodman, M.F.
J. of Biol. Chem. 268, 15935-15943 (1993).
"Direct Sequencing of Hepatitis B virus DNA from human sera using non-radioactive methods."
Escarceller, M., Arranz, A., Rodriguez-Frias, F., Cotrina, M., Jardi, R., Pons, A., San Segundo,
B., Eritja, R.
Mol. Biol. (Life Sci. Adv.), 12, 77-84 (1993).
"Use of a base labile Protected derivative of 6-mercaptohexanol for the preparation of
oligonucleotides containing a thiol group at the 5'-end."
De la Torre, B., Aviñó, A., Escarceller, M., Royo, M., Albericio, F., Eritja, R.
Nucleosides & Nucleotides 12, 993-1005 (1993).
"Both O-4-methylthymine and O-4-ethylthymine preferentially form alkyl T.G pairs which do not
block in vitro replication in a defined sequence."
Dosanjh, M.K., Menichini, P., Eritja, R., and Singer, B.
Carcinogenesis 14, 1915-1919 (1993).
"Gel-phase 31
P-NMR. A new analytical tool to evaluate solid phase oligonucleotide synthesis."
Bardella, F., Eritja, R., Pedroso, E. and Giralt, E.
Bioorg. Med. Chem. Lett. 3, 2793-2796 (1993).

"Kinetics of deoxyribonucleotide insertion and extension at abasic template lesions in different
sequence contexts using HIV-1 reverse transcriptase."
Cai, H., Bloom, L.B., Eritja, R., Goodman, M.F.
J. of Biol. Chem. 268, 23567-23572 (1993).
"Strategies and tactics for the solid-phase synthesis of cysteine-containing peptides."
Albericio, F., Royo, M., Munson, M.C., Solé, N.A., Van Abel, R.J., Alsina, J., Carcía-
Echevarria, C., Slomczynska, U., Eritja, R., Pons, M., Giralt, E., Barany, G.
Peptide Chemistry 1992, (H.Yanaihara Ed.) ESCOM Ltd, pp19-23 (1993).
“Structural kinetics of base excision from DNA with bacteriophage-T4 polymerase”
Otto, M.R., Bloom, L.B., Eritja, R., Goodman, M.F., Beechem, J.M.
Biophys. J., 64, A181, Part 2, (1993).
“Dynamics of DNA containing TATA box regions. A time resolved fluorescence study.”
Otto, M.R., Bloom, L.B., Eritja, R., Goodman, M.F., Beechem, J.M.
Biophys. J., 64, A180, Part 2, (1993).
“Structural kinetics and dynamics of deoxynucleotide excision from DNA by the bacteriophage-
T4 polymerase. A time resolved and stopped-flow fluorescence study.”
Otto, M.R., Bloom, L.B., Eritja, R., Reha-Krantz, L., Goodman, M.F., Beechem, J.M.
FASEB J., 7, A1293 (1993).
“Partitioning of T4 polymerase bound DNA between polymerase and exonuclease sites. A
stopped-flow kinetic and time-resolved fluorescence dynamics study.
Otto, M.R., Bloom, L.B., Eritja, R., Reha-Krantz, L., Goodman, M.F., Beechem, J.M.
Biophys. J., 66, A369 (1994).
"Complete chemical synthesis of a fully active transcriptional repressor."
Del Solar, G., Albericio, F., Eritja, R., Espinosa, M.
Proc. Natl. Acad. Sci. USA 91, 5178-5182 (1994).
"Synthesis of oligodeoxyribonucleotides containing 2,6-diaminopurine."
Cano, A., Goodman, M.F., and Eritja, R.
Nucleosides Nucleotides 13, 501-509 (1994).
"Nucleoside insertion and primer extension at abasic template sites in different sequence
contexts."
Goodman, M.F., Cai, H., Bloom, L.B. and Eritja, R.
Ann. New York Acad. Sci. 726, 132-143 (1994).
"Criteria for the economic large scale solid-phase synthesis of oligonucleotides."
Montserrat, F.X., Grandas, A., Eritja, R. and Pedroso, E.
Tetrahedron 50, 2617-2622 (1994).

"Solid-phase N-glycopeptide synthesis using allyl side-chain protected Fmoc-amino acids."
Kates, S.A., de la Torre, B.G., Eritja, R., Albericio, F.
Tetrahedron Lett. 35, 1033-1034 (1994).
"Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids."
De la Torre, B.G., Aviñó, A., Tarrason, G., Piulats, J., Albericio, F., Eritja, R.
Tetrahedron Lett. 35, 2733-2736, (1994).
"Pre-steady-state kinetic analysis of sequence-dependent nucleotide excision by the 3'exonuclease
activity of bacteriophage T4 DNA polymerase."
Bloom, L., Otto, M.R., Eritja, R., Reha-Krantz, L., Goodman, M.F., Beechem, J.M.
Biochemistry, 33, 7576-7586 (1994).
"Functional regulation of PECAM-1 by transforming growth factor-b1 in promonocytic U-937
cells."
Lastres, P., Almendro, N., Bellón, T., López-Guerrero, J.A., Eritja, R., Bernabéu, C.
J. of Immunology, 153, 4206-4218 (1994).
"Use of oligonucleotide-alkaline phosphatase conjugates as non-radioactive probes for rapid
analysis of a proteinase inhibitor gene from Zea mays."
Cordero, M.J., Murillo, M.I., Arroyo, D., Eritja, R., and San Segundo, B.
Plant Molecular Biology Reporter 12, 265-273 (1994).
"Use of Npe-protecting groups for the preparation of oligonucleotides without using nucleophiles
during the final deprotection."
Aviñó, A. and Eritja, R.
Nucleosides Nucleotides 13, 2059-2069 (1994).
"A simple method for N-15 labelling of exocyclic amino groups in synthetic
oligodeoxynucleotides."
Acedo. M., Fàbrega, C., Aviñó, A., Goodman, M., Fagan, P., Wemmer, D., and Eritja, R.
Nucleic Acids Res. 22, 2982-2989 (1994).
"Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG)
complexed with the minor-groove-binding drug Hoechst 33258."
Vega, M.C.; García Sáez, I.; Aymamí, J.; Eritja, R.; van der Marel, G.; van Boom, J.; Rich, A.;
Coll, M.
Eur. J. Biochem. 222, 721-726 (1994).
"Preparation of oligonucleotides containing non-natural base analogues."
Eritja, R., Acedo, M., Avinyó, A., Fàbrega, C.
Nucleosides and Nucleotides 14, 821-824 (1995).
"Synthesis and properties of oligonucleotides containing the mutagenic base O 4
-
benzylthymidine."
Fàbrega, C., Eritja, R., Sinha, N.D., Dosanjh, M.K., Singer, B.
Biorg. Med. Chemistry 3, 101-108 (1995).

"A convenient method for the preparation of N 2
,N 2
-dimethylguanosine."
Aviñó, A., Mayordomo, A., Espuny, R., Bach, M., Eritja, R.
Nucleosides Nucleotides 14, 1613-1617 (1995).
"Digoxigenin-labeled phosphorothioate oligonucleotides : a new tool for the study of cellular
uptake."
Tarrasón, G., Bellido, D., Eritja, R., Vilaró, S., Piulats, J.
Antisense Res. Dev. 5, 193-201 (1995).
"Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids."
de la Torre, B.G., Aviñó, A., Albericio, F., Eritja, R.
Peptides 1994, (Maia, H.L.S. Ed.), ESCOM, Leiden 1995, 303-304.
"Preparation of oligonucleotide-dexamethasone conjugates."
Acedo, M., Tarrason, G., Piulats, J., Mann, M., Wilm, M., Eritja, R.
Bioorg. & Med. Chem. Lett. 5, 1577-1580 (1995).
"Synthesis and biophysical and biological properties of oligonucleotides containing 2-aza-2'deoxyinosine."
Acedo, M., De Clercq, E., Eritja, R.
J. Org. Chem. 60, 6262-6269 (1995).
"Preparation and properties of oligodeoxynucleotides containing 4-O-butylthymine, 2fluorohypoxanthine
and 5-azacytosine."
Aviñó, A., Güimil-Garcia, R., Marquez, V.E., Eritja, R.
Bioorganic & Medicinal Chem. Lett., 5, 2331-2336 (1995).
"Dam methylase from Escherichia coli: Kinetic studies using modified DNA oligomers:
Hemimethylated substrates."
Marzabal, S., DuBois, S., Thielking, V., Cano, A., Eritja, R., Guschlbauer, W.
Nucleic Acids Res. 23, 3648-3655 (1995).
"Kinetic studies of MvaI DNA methyltransferase interaction with modified oligonucleotide
duplexes."
Gromova, E.S., Oretskaya, S.L., Eritja, R., Guschlbauer, W.
Biochem. Mol. Biol. Intl. 36, 247-255 (1995).
"4,4'-Bis(2-amino-6-methylpyrimidyl) disulfide and benzenesulfonyltetrazole."
F. Albericio, S. A. Kates, R. Eritja
Encyclopedia of Reagents for Organic Chemistry.
John Willey & Sons, Ltd. 1995, Vol. 1 pp 421 and Vol. 6 pp 4058.
"Divalent zinc cations induce the formation of two distinct homoduplexes of a d(GA) 20 DNA
sequence."
Ortiz-Lombardía, M., Eritja, R., Azorín, F., Kypr, J., Tejralova, I., Vorlickova, M.

Biochemistry 34, 14408-14415 (1995).
"Preparation of oligonucleotides containing 5-bromouracil and 5-methylcytidine."
Ferrer, E., Fàbrega, C., Güimil-García, R., Azorín, F., Eritja, R.
Nucleosides & Nucleotides 15, 907-921 (1996).
"Active site properties of monomeric triosephosphate (monoTIM) as deduced from mutational
and strucutural studies."
Schliebs, W., Thanki, N., Eritja, R., Wierenga, R.
Protein Science 5, 229-239 (1996).
"NMR study of the conformation of the 2-aminopurine:cytosine mismatch in DNA."
Fagan, P.A., Fabrega, C., Eritja, R., Goodman, M.F., Wemmer, D.E.
Biochemistry 35, 4026-4033 (1996).
"Synthesis of 1,2-diacyl-sn-glycerophosphatidylserine from egg phosphatidylcholine by
phosphoramidite methodology"
Morillo, M., Sagristá, M.L., de Madariaga, M.A., Eritja, R.
Lipids 31, 541-546 (1996).
"New carbamate supports for the preparation of 3'-amino-modified oligonucleotides."
Aviñó, A., Güimil-Garcia, R., Albericio, F., Mann, M., Wilm, M., Neubauer, G., Eritja, R.
Biorganic & Medicinal Chem. 4, 1649-1658 (1996).
"A comparative study of supports for the synthesis of oligonucleotides without using ammonia."
Aviñó, A., Güimil García, R., Díaz, A., Albericio, F., Eritja, R.
Nucleosides Nucleotides 15, 1871-1889 (1996).
"Spectroscopy and calorimetric characterizations of DNA duplexes containing 2-aminopurine."
Law, S.M., Eritja, R., Goodman, M.F., Breslauer, K.J.
Biochemistry 35, 12329-12337 (1996).
"Through-bond correlation of adenine H2 and H8 protons in unlabeled DNA fragments by
HMBC spectroscopy."
van Dongen, M., Wijmenga, S.S., Eritja, R., Azorín, F., Hilbers, C.H.
J. Biomol. NMR, 8, 207-212 (1996).
“Exploring the dynamics and reaction mechanism of the bacteriophage T4 DNA polymerase:
Duplex DNA complex. A time resolved and stopped flow fluorescence quenching study.”
Otto, M.R., Gillmor, S.D., Eritja, R., Reha-Krantz, L., Goodman, M.F., Beechem, J.M.
Biophys. J., 70, SU487, Part 2, (1996).
”N -Tritylamino acids: Synthesis and application in solid phase peptide synthesis.”
De la Torre, B.G., Marcos, M.A., Alsina, J., Eritja, R., Albericio, F.
Peptides 1996, (Maia, H.L.S. Ed.), ESCOM, Leiden 1997, 327-328.
”Synthesis of 64 Cu and 99m Tc labelled oligodeoxynucleotides using CPTA-phosphoramidite.”

Wagner, S., Oberdorfer, R., Eritja, R., Zeisler, S., Titsch, U., Eisenhut, M.
J. Label. Compd. Radiopharm., 40, 476-478 (1997).
"Abasic translesion synthesis by DNA polymerase β violates the "A-rule": Nucleotide
incorporation by human DNA polymerase β and α at an abasic lesion in different sequence
contexts."
Efratis, E., Tocco, G., Eritja, R., Wilson, S.H., Goodman, M.F.
J. Biol. Chem. 272, 2559-2569 (1997).
"Synthesis of copper-64 and technetium-99M labeled oligonucleotides with macrocyclic
ligands".
Wagner, S., Eisenhut, M., Eritja, R., Oberdorfer, F.
Nucleosides & Nucleotides, 16, 1789-1792 (1997).
"Synthesis and properties of oligonucleotides containing 5-aza-2'-deoxycytidine."
Eritja, R., Marquez, V.E., Güimil García, R.
Nucleosides Nucleotides, 16, 1111-1114 (1997).
"A simple method for the synthesis of 2'-O-alkylguanosine derivatives."
Grøtli, M., Douglas, M., Beijer, B., Eritja, R., Sproat, B.
Bioorg. Med. Chem. Lett., 7, 425-428 (1997).
"Initiation of replication of plasmid pMV158: Mechanisms of DNA strand transfer reactions
mediated by the initiator RepB protein."
Moscoso, M., Eritja, R., Espinosa, M.
J. Mol. Biol., 268, 840-856 (1997).
"Preparation of oligonucleotides containing non-natural base analogs."
Eritja, R., Adam, V., Aviñó, A., Díaz, A.R. , Fàbrega, C., Ferrer, E., Grøtli, M., Güimil García,
R., Hofmann, M., Márquez, V.E., Wiersma, M.
Nucleosides Nucleotides 16, 697-702 (1997).
"Synthesis and biophysical properties of oligonucleotides containing 5-amino-2'-deoxyuracil and
5-N-acetamido-2'-deoxyuracil."
Ferrer, E., Neubauer, G., Mann, M., Eritja, R.
J.C.S. Perkin Trans. I, 2051-2058 (1997).
"Protection of the guanine residue during synthesis of 2'-O-alkylguanosine derivatives."
Grøtli, M., Douglas, M., Beijer, B., Güimil García, R., Eritja, R., Sproat, B.
J. C. S. Perkin Trans. I, 2779-2788 (1997).
"Synthesis of oligodeoxynucleotides containing N 6
-[ 13
C-methyl]adenine and N 2
methyl]guanine. "
Hofmann, M., Acedo, M., Fagan, P., Wemmer, D., Eritja, R., Díaz, A.R.
J.C.S. Perkin Trans. I, 1825-1828, (1997).
-[ 13
C

"Synthesis of oligodeoxynucleotides containing 2-substituted guanine derivatives using 2-fluoro-
2'-deoxyinosine as common nucleoside precursor."
Díaz, A.R., Eritja, R., Güimil García, R.
Nucleosides & Nucleotides 16, 2035-2051, (1997).
"Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers:
Nonmethylated substrates."
Thielking, V., Du Bois, S., Eritja, R., Guschlbauer, W.
Biol. Chem. 378, 407-415 (1997).
"Preparation and properties of oligodeoxynucleotides containing 5-iodo-uracil, 5-bromo- and 5iodo-cytosine."
Ferrer, E., Wiersma, M., Kazimierczak, B., Müller, C.W., Eritja, R.
Bioconjugate Chem. 8, 757-761 (1997).
"Solid-phase synthesis of Branched RNA and Branched DNA/RNA Chimeras."
Grøtli, M., Eritja, R., Sproat, B.
Tetrahedron 53, 11317-11346 (1997).
"Preparation, purification and analysis of synthetic oligonucleotides suitable for microinjection
experiments."
Güimil García, R. and Eritja, R.
Microinjection and transgenesis. Strategies and protocols.(A. Cid-Arregui, A. García-Carrancá,
Eds) Springer Laboratory Manuals, Springer, Berlin pp 95-112, (1997).
"DNA-binding ligands from peptide libraries containing unnatural amino acids."
Lescrinier, T., Hendrix, C., Kerremans, L., Rozenski, J., Link, A., Samyn, B., Van Aerschot, A.,
Lescrinier, E., Eritja, R., Van Beeumen, J., Herdewijn, P.
Chem. Eur. J. 4, 425-433 (1998)
"Studies on the synthesis of oligonucleotides containing photoreactive nucleosides: 2-azido-2'deoxyinosine
and 8-azido-2'-deoxyadenosine."
Fàbrega, C., Güimil García, R., Díaz, A.R., Eritja, R.
Biol. Chem. 379, 527-533 (1998).
"Tandem 5'-GA:GA-3' mismatches account for the high stability of the fold-back structures
formed by the contromeric Drosophilla dodeca-satellite.
Ortíz-Lombardía, M., Cortés, A., Huertas, D., Eritja, R., Azorín, F.
J. Mol. Biol., 277, 757-762 (1998).
"A monoclonal antibody that specifically recognizes m 6 A nucleoside"
Espuny, R., Castro, A., Codony, C., Eritja, R., Bach-Elias, M.
Nucleosides Nucleotides 17, 2189-2197 (1998).
"2'-O-Propargyl oligoribonucleotides: Synthesis and hybridisation."
Grøtli, M., Douglas, M., Eritja, R., Sproat, B.S.
Tetrahedron 54, 5899-5914 (1998).

"A second-step splicing activity is conserved from yeast to human"
Cicarelli, R.M.B., Khaouja, A., Codony, C., Espuny, R., Eritja, R., Bach-Elias, M.
Biochem. Biophys. Res. Comm. 247, 204-206, (1998).
"Exonuclease-polymerase active site partitioning of primer-template DNA strands and
equilibrium Mg 2+
binding properties of bacteriophage T4 polymerase."
Beechem, J.M., Otto, M.R., Bloom, L.B., Eritja, R., Reha-Krantz, L.J., Goodman, M.F.
Biochemistry 37, 10144-10155 (1998).
"Synthesis of oligodeoxynucleotides containing N 4
-mercaptoethylcytosine and their use in the
preparation of oligonucleotide-peptide conjugates carrying c-myc tag sequence."
Gottschling, D., Seliger, H., Tarrasón, G., Piulats, J., Eritja, R.
Bioconjugate Chem., 9, 831-837 (1998).
"Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro
lesion bypass dependent on UmuD' 2 C mutagenic complex and RecA protein."
Tang, M., Bruck, I., Eritja, R., Turner, J., Frank, E.G., Woodgate, R., O'Donnell, M., Goodman,
M.F.
Proc. Natl. Acad. Sci. USA 95, 9755-9760 (1998).
"Triple helix stabilization properties of oligonucleotides containing 8-amino-2'-deoxyguanosine."
Güimil-García, R., Bachi, A., Eritja, R., Luque, F.J., Orozco, M.
Bioorg. Med. Chem. Lett. 8, 3011-3016 (1998).
“Antisense oligonucleotides as anticancer agents.”
Herdewijn, P., Saison-Behmoaras, E., Van Aerschot, A., Leserman, L., Eritja, R., Pfleiderer, W.
Biomedical and Health Research Vol 24, pp 182-189, (1998).
"Preparation of N 2
,N 2
,7-tri-methylguanosine affinity columns."
Espuny, R., Bahia, D., Cicarelli, M.B., Codony, C., Khaouja, A., Aviñó, A.M., Eritja, R., Bach-
Elias, M.
Nucleosides Nucleotides 18, 125-136 (1999).
"A convenient route for the preparation of peptide nucleic acid monomers carrying acid-labile
groups for the protection of the amino function."
Ferrer, E., Eisenhut, M., Eritja, R.
Lett. in Peptide Science, 6, 209-219 (1999).
"Modified oligonucleotides with triple-helix stabilization properties."
Eritja, R., Ferrer, E., Güimil-García, R., Orozco, M.
Nucleosides Nucleotides, 18, 1619-1621 (1999).
"The structure of plasmid-encoded transcriptional repressor CopG, unliganded and bound to its
operator."

Gomis-Rüth, F.X., Solà, M., Acebo, P., Párraga, A., Guasch, A., Eritja, R., González, A.,
Espinosa, M., del Solar, G., Coll, M.
Embo, J., 17, 7404-7415 (1998).
"Theoretical calculations, synthesis and base-pairing properties of oligonucleotides containing 8amino-2'-deoxyadenosine."
Güimil-García, R., Ferrer. E., Macías, M.J., Eritja, R., Orozco, M.
Nucleic Acids Res., 27, 1991-1998 (1999).
"Action-at-a-distance" mutagenesis. 8-Oxo-7,8-dihydro-2'-deoxyguanosine causes base
substitution errors at neighboring template sites when copied by DNA polymerase β
Efrati, E., Tocco, G., Eritja, R., Wilson, S.H., Goodman, M.F.
J. Biol. Chem., 274, 15920-15926 (1999).
"Crystal structure of a four-way DNA Holliday junction."
Ortiz-Lombardía, M., González, A., Eritja, R., Aymamí, J., Azorín, F., Coll, M.
Nature Structural Biology, 6, 913-917 (1999).
"Synthesis and binding properties of oligonucleotides carrying nuclear localization sequences"
de la Torre, B.G., Albericio, F., Saison-Behmoaras, E., Bachi, A., Eritja, R.
Bioconjugate Chem., 10, 1005-1012 (1999).
"A novel p34cdc2-binding and activating protein that is necessary and sufficient to trigger G2/M
progression in Xenopus oocytes"
Ferby, I., Blazquez, M., Palmer, A., Eritja, R., Nebreda, A.R.
Genes & Development, 13, 2177-2189 (1999).
"Synthesis of oligonucleotide-peptide conjugates and nucleopeptides."
Eritja, R.
Solid-Phase synthesis. A practical guide. (S. Kates, F. Albericio Eds) Marcel Dekker, New York,
pp529-548 (2000)
"Intracellular distribution of digoxigenin-labeled phosphorothioate oligonucleotides."
Tarrasón, G., Bellido, D., Eritja, R., Vilaró, S., Piulats, J.
Methods in Enzymol., 313, 257-268 (2000)
"Synthesis of peptide nucleic acid-peptide chimeras carrying c-myc TAG-sequence"
Gottschling, D., Seliger, H., Tarrasón, G., Piulats, J., Wiersma, M., Eritja, R.
Letters in Peptide Science, 7, 35-39, (2000).
"Synthesis and hybridization properties of DNA-PNA chimeras carrying 5-bromouracil and 5methylcytosine"
Ferrer, E., Shevchenko, A., Eritja, R.
Bioorganic & Medicinal Chemistry, 8, 291-297 (2000).
Duplex-stabilization properties of oligodeoxynucleotides containing N 2 -substituted guanine
derivatives.”

Eritja, R., Díaz, A.R., Saison-Behmoaras, E.
Helv. Chim. Acta, 83, 1417-1423 (2000).
“Synthesis and properties of 2’-deoxycytidine triphosphate carrying c-myc TAG sequence.”
Hinz, M., Gottschling, D., Eritja, R., Seliger, H.
Nucleosides Nucleotides & Nucleic Acids, 19, 1543-1552 (2000).
“Preparation and evaluation of tumor-targeting peptide-oligonucleotide conjugates.”
Mier, W., Eritja, R., Mohammed, A., Haberkorn, U., Eisenhut, M.
Bioconjugate Chemistry, 11, 855-860 (2000).
“Synthesis of peptide nucleic acid oligomers carrying 5-methylcytosine derivatives by
postsynthetic substitution.”
Ferrer, E., Eritja, R.
Letters in Peptide Science, 7, 195-206 (2000).
“DNA-triplex stabilizing properties of 8-aminoguanine.”
Soliva, R., Güimil García, R., Blas, J.R., Eritja, R., Asensio, J.L., González, C., Luque, F.J.,
Orozco, M.
Nucleic Acids Res., 28, 4531-4539 (2000).
“Duplex-stabilization properties of oligodeoxynucleotides containing N 2 -substituted guanine
derivatives.”
Eritja, R., Díaz, A.R., Saison-Behmoaras, E
Perspectives in Nucleoside and Nucleic Acid Chemistry, Wiley-VCH, Weinheim, 2000, 353-359.
“An improved synthesis of N-[(9-hydroxymethyl)-2-fluorenyl] succinamic acid (HMFS), a
versatile handle for the solid-phase synthesis of biomolecules.”
Albericio, F., Cruz, M., Debéthune, L., Eritja, R., Giralt, E., Grandas, A., Marchán, V., Pastor,
J.J., Pedroso, E., Rabanal, F., Royo, M.
Synthetic Comm. 31, 225-232 (2001).
“Synthesis and properties of oligonucleotides containing 8-bromo-2’-deoxyguanosine”
Fábrega, C., Macías, M.J., Eritja, R.
Nucleosides Nucleotides & Nucleic Acids, 20, 251-260 (2001).
“The effect of amino groups on the stability of DNA duplexes and triplexes based on purines
derived from inosine”
Cubero, E., Güimil García, R., Luque, F.J., Eritja, R., Orozco, M.
Nucleic Acids Res., 29, 2522-2534 (2001)
“Protonation studies and multivariate curve resolution on oligodeoxynucleotides carrying the
mutagenic base 2-aminopurine”
Gargallo, R., Vives, M., Tauler, R., Eritja, R.
Biophys. J., 81, 2886-2896 (2001).

“Parallel-stranded hairpins containing 8-aminopurines. Novel efficient probes for triple-helix
formation.”
Aviñó, A., Morales, J.C., Frieden, M., de la Torre, B.G., Güimil-García, R., Cubero, E., Luque,
F.J., Orozco, M., Azorín, F., Eritja, R.
Bioorg. Med. Chem. Lett., 11, 1761-1763 (2001).
“Plasmid transcriptional represor CopG oligomerises to render helical superstructures unboud
and in complexes with oligonucleotides.”
Costa, M., Solá, M., del Solar, G., Eritja, R., Hernández-Arriaga, A.M., Espinosa, M., Gomis-
Ruth, F.X., Coll, M.
J. Mol. Biol., 310, 403-417 (2001).
“Preparation and preclinical development of tumor-targeting peptide-PNA conjugates.”
Mier, W., Eritja, R., Mohammed, A., Haberkorn, U., Eisenhut, M.
J. Nuclear Med. 42, 428 Suppl. S (2001).
“Synthesis of oligonucleotide inhibitors of DNA (Cytosine-C5) methyltransferase containing 5azacytosine
residues at specific sites.”
Güimil García, R., Brank, A.S., Marquez, V.E., Christman J.K., Eritja, R.
Antisense and Nucleic Acid Drug Development, 11, 369-378 (2001).
“Synthesis and labelling of peptide nucleic acid oligomers conjugated to octreotate”
Mier, W., Eritja, R., Mohammed, A., Haberkorn, U., Eisenhut, M.
J. of Labelled Comp. and Radiopharm. 44, S954-S956 (2001).
“Hoogsteen-based parallel-stranded duplexes of DNA. The effect of 8-amino derivatives.”
Cubero, E., Aviñó, A., de la Torre, B.G., Frieden, M., Eritja, R., Luque, F.J., González, C.,
Orozco, M.
J. Am. Chem. Soc., 124, 3133-3142 (2002).
“Additional binding sites for anionic phospholipids and Ca 2+ ions in the crystal structures of
complexes of the C2 domain of protein kinase Cα.”
Ochoa, W.F., Corbalán-García, S., Eritja, R., Rodríguez-Alfaro, J.A., Gómez-Fernández, J.C.,
Fita, I., Verdaguer, N.
J. Mol Biol. 320, 277-291 (2002).
“Solid-phase peptide synthesis using N α -trityl-amino acids.”
de la Torre, B.G., Marcos, M.A., Eritja, R., Albericio, F.
Letters in Peptide Sience 8, 331-338 (2002).
“Properties of triple helices formed by parallel-stranded hairpins containing 8-aminopurines.”
Aviñó, A., Frieden, M., Morales, J.C de la Torre, B.G., Güimil-García, R., Azorín, F., Gelpí,
J.L., Orozco, M., González, C., Eritja, R.
Nucleic Acids Res., 30, 2609-2619 (2002).
“Nucleic acid triple helices: Stability effects of nucleobase modifications.”
Robles, J., Grandas, A., Pedroso, E., Luque, F.J., Eritja, R., Orozco, M.

Curr. Org. Chem., 6, 1333-1368, (2002).
“Iodouracil-mediated photo-cross-linking of DNA to Eco RII restriction endonuclease under the
catalytic conditions.”
Babkina, O.V., Shashkov, A.A., Chutko, C.A., Dzhiddzhoev, M.S., Eritja, R., Gromova, E.S.
Photochemical & Photobiological Chemistry, 636-640 (2002).
“Synthesis of oligonucleotides carrying anchoring groups and their use in the preparation of
oligonucleotide-gold conjugates.”
De la Torre, B.G., Morales, J.C., Aviñó, A., Iacopino, D., Ongaro, A., Fitzmaurice, D., Murphy,
D., Doyle, H., Redmond, G., Eritja, R.
Helvetica Chimica Acta, 85, 2594-2607 (2002).
“Oligonucleotide conjugates: synthesis and properties.”
Eritja, R., Tarrasón, G., de la Torre, B.G., Piulats, J.
Recent Research Developments in Bioconjugate Chemistry, 1, 55-65 (2002).
“Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides
containing 5-aza-2´-deoxycytidine: Examination of the intertwined roles of co-factor, target
transition state structure and enzyme conformation.”
Brank, A.S., Eritja, R., Güimil García, R., Marquez, V.E., Christman J.K.
J. Mol. Biol., 323, 53-67 (2002).
“Toward DNA-Mediated self assembly of carbon nanotube-based molecular devices.”
Williams, K.A., Veenhuizen, P., de la Torre B.G., Eritja, R., Dekker, C.
AIP Conf. Proc., 633, 444-448 (2002).
“Biofunctionalization of silica-coated CdTe and gold nanocrystals.”
Schroedter, A., Weller, H., Eritja, R., Ford, W.E., Wessels, J.M.
Nano Lett., 2, 1363-1367 (2002).
“Carbon nanotubes with DNA recognition.”
Williams, K.A., Veenhuizen, P.T.M., de la Torre, B.G., Eritja, R., Dekker, C.
Nature, 420, 761 (2002).
“DNA duplexes containing photoreactive derivatives of 2’-deoxyuridine as photocrosslinking
probes for EcoRII DNA Methyltransferase-substrate interaction.”
Koudan, E.V., Subach, O.M., Korshunova, G.A., Romanova, E.A., Eritja, R., Gromova, E.S.
J. Biomol. Struct. Dyn., 20, 421-428 (2002).
“DNA-controlled assembly of protein-modified gold nanocrystals.”
Cobbe, S.; Connolly, S.; Nagle, L.; Eritja, R.; Fitzmaurice, D.; Ryan, D.
J. Phys. Chem. B, 107, 470-477 (2003).
“Synthesis of labelled PNA oligomers by a post-synthetic modification approach.”
De la Torre, B.G., Eritja, R.
Biorganic & Med. Chem. Lett., 13, 391-393 (2003).

“Properties of triple helices formed by oligonucleotides containing 8-aminopurines”
Aviñó, A., Frieden, M., Morales, J.C., de la Torre, B.G., Güimil-García, R., Orozco, M.,
González, C., Eritja, R.
Nucleosides, Nucleotides & Nucleic Acids, 22, 645-648 (2003).
“Convenient synthesis of 8-amino-2’-deoxyadenosine”
Friden, M., Aviñó, A., Eritja, R.
Nucleosides, Nucleotides & Nucleic Acids, 22, 193-202 (2003).
“Peptide-PNA conjugates: Targeted transport of antisense therapeutics into tumors.”
Mier, W., Eritja, R., Mohammed, A., Haberkorn, U., Eisenhut, M.
Angew. Chem. Int. Ed., 42, 1968-1971 (2003).
“Imaging the DNA and nanoparticle components of a self-assembled nanoscale architecture.”
Iacopino, D., Ongaro, A., Nagle, L., Eritja, R., Fitzmaurice, D.
Nanotechnology, 14, 447-452 (2003).
“Synthesis and properties of radiolabeled CPTA-oligonucleotides.”
Wagner, S., Eritja, R., Zuhayra, M., Oberdorfer, F., Mohammed, A., Mier, W., Haberkorn, U.,
Eisenhut, M.
J. Label. Compd. Radiopharm., 43, 175-186 (2003).
“Analytical resolution of parallel and antiparallel oligonucleotide triple helices formation and
melting processes by means of Multivariate Curve Resolution”
Jaumot, J., Eritja, R., Aviñó, A., Tauler, R., Gargallo, R.
J. Biomol. Struct. Dyn., 21, 267-278 (2003).
“Synthesis of branched oligonucleotides as templates for the assembly of nanomaterials.”
Grimau, M.G., Iacopino, D., Aviñó, A., de la Torre, B.G., Ongaro, A., Fitzmaurice, D., Wessels,
J., Eritja, R.
Helv. Chim. Acta, 86, 2814-2826 (2003).
“BIOAND project: Developing methodologies towards nanoelectronic-devices using
nanoparticles assembled by DNA and proteins.”
Wessels, J.M., Ford, W.E., Harnack, O., Yasuda, A., Weller, H., Schroedter, A., Schevchenko,
E., Pacholski, C., Fitzmaurice, D., Iacopino, D., Ongaro, A., Pum, D., Sleytr, U., Györvary, E.,
Moll, D., Redmond, G., Quinn, A.J., Doyle, H., Greer, J.C., Morales, J.C., de la Torre, B.G.,
Eritja, R.
Phantoms Newsletter, 10/11, 7-10 (2003).
“Antiparallel triple helices. Structural characteristics and stabilization by 8-amino derivatives.”
Aviñó, A., Cubero, E., González, C., Eritja, R., Orozco, M.
J. Am. Chem. Soc., 125, 16127-16138 (2003).
“Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside
(zebularine) at the GCGC recognition domain”

Marquez, V.E., Eritja, R., Kelley, J.A., Vanbemmel, D., Christman, J.K.
Ann. NY Acad. Sci., 1002, 154-164 (2003).
“4-Hydroxymethyl-3’-nitrobenzoic acid” and N-[9-(Hydroxymethyl)-2-fluorenyl] succinamic
acid”.
De la Torre, B.G., Eritja, R., Albericio, F.
Electronic encyclopedia of reagents for organic synthesis (e-EROS), update 3+4, (2003).
“Synthesis, stability and protonation studies of a self-complementary dodecamer containing the
modified nucleoside 2’-deoxyzebularine.”
Vives, M., Eritja, R., Tauler, R., Marquez, V.E., Gargallo, R.
Biopolymers, 73, 27-43 (2004).
“Synthesis and triple-helix stabilization properties of branched oligonucleotides carrying 8aminoadenine
moieties.”
Aviñó, A., Grimau, M.G., Frieden, M., Eritja, R.
Helv. Chim. Acta, 87, 303-316 (2004).
“Synthesis and properties of oligonucleotides carrying cryptolepine derivatives.”
Eritja, R.
Chem. Biodiv., 1, 289-295 (2004).
“Transgenic rice plants expressing the antifungal AFP protein from the mold Aspergillus
giganteus show enhanced resistance to the rice blast fungus Magnaporthe grisea.
Coca, M., Bartolotti, C., Rufat, M., Peñas, G., Eritja, R., Tharreau, D., Martinez del Pozo, A.,
Messeguer, J., San Segundo, B.
Plant Mol. Biol., 54, 254-259 (2004).
“Monitoring denaturation behaviour and comparative stability of DNA triple helices using
oligonucleotide-gold nanoparticle conjugates.”
Murphy, D., Eritja, R., Redmond, G.
Nucleic Acids Res., 32, e65 (2004).
“DNA templated assembly of a protein-functionalized nanogap electrode.”
Ongaro, A., Griffin, F., Nagle, L., Iacopino, D., Eritja, R., Fitzmaurice, D.
Adv. Materials, 16, 1800-1803 (2004).
“Synthesis of oligonucleotide-peptide conjugates carrying the c-myc peptide epitope as
recognition system”
Frieden, M., Aviñó, A., Tarrasón, G., Escorihuela, M., Piulats, J., Eritja, R.
Chem. Biodiv., 1, 930-938 (2004).
“Effect of base stacking on the relative thermodynamic stability of oligonucleotide complexes: A
spectroscopic study”
Murphy, D., Doyle, H., Eritja, R., Redmond, G.
J. Biomol. Struc. Dyn., 22, 195-204 (2004).

“Synthesis of oligoribonucleotides containing 4-thiouridine using the convertible nucleoside
approach and the Fpmp group.”
Aviñó, A., Güimil-García, R., Eritja, R.
Nucleosides, Nucleotides & Nucleic Acids, 23, 1767-1777 (2004).
“Hybridization and melting behaviour of peptide nucleic acid-oligonucleotide chimeras
conjugated to gold nanoparticles.”
Murphy, D., Redmond, G., de la Torre, B.G., Eritja, R.
Helv. Chim. Acta, 87, 2727-2734 (2004).
“Parallel- and antiparallel-tail-clamps hairpins increase the efficiency of triplex formation with
structured DNA and RNA targets.”
Nadal, A., Eritja, R., Esteve, T., Plà, M.
ChemBioChem, 6, 1034-1042 (2005).
“Synthesis and triplex-forming properties of cyclic oligonucleotides with G,A-antiparallel
strands.”
Grimau, M.G., Gargallo, R., Aviñó, A., Eritja, R.
Chem. Biodiv., 2, 275-285 (2005).
“Toward an ICPMS-Linked DNA assay based on gold nanoparticles immunoconnected through
peptide sequences.”
Merkoçi, A., Aldavert, M., Tarrasón, G., Eritja, R., Alegret, S.
Anal. Chem., 77, 6500-6503 (2005).
“A straightforward synthesis of 5’-peptide oligonucleotide conjugates using N α -Fmoc-protected
amino acids.”
Ocampo, S.M., Albericio, F., Fernández, I., Vilaseca, M., Eritja, R.
Org. Lett., 7, 4349-4352 (2005).
“Magnetically trigged direct electrochemical detection of DNA hybridization using Au67
quantum dot as electrical tracer.”
Pumera, M., Castañeda, M.T., Pividori, M.I., Eritja, R., Merkoçi, A., Alegret, S.
Langmuir, 21, 9625-9629 (2005).
“DNA-templated assembly of nanoscale architectures.”
Stanca, S.E., Ongaro, A., Eritja, R., Fitzmaurice, D.
Nanotechnology 16, 1905-1911 (2005).
“Strand displacement of double-stranded DNA by triples-forming antiparallel purine-hairpins.”
Coma, S., Noé, V., Eritja, R., Ciudad, C.J.
Oligonucleotides, 15, 269-283 (2005).
“DNA-templated assembly of nanoscale architectures for next-generation electronic devices.”
Stanca, S.E., Eritja, R., Fitzmaurice, D.
Faraday Discus. 131, 155-165 (2006).

“Resolution of a structural competition involving dimeric G-quadruplex and its C-rich
complementary strand.”
Jaumot, J., Eritja, R., Tauler, R., Gargallo, R.
Nucleic Acids Res., 34, 206-216 (2006).
“Destabilization of quaduplex DNA by 8-aminoguanine.”
Lopez de la Osa, J., Gonzalez, C., Gargallo, R., Rueda, M., Cubero, E., Orozco, M., Aviñó, A.,
Eritja, R.
ChemBioChem, 7, 46-48 (2006).
“Efficient sequence-specific purification of Listeria innocua mRNA species by triplex affinity
capture with parallel tail-clamps.”
Nadal, A., Coll, A., Aviñó, A. Esteve, T., Eritja, R., Pla, M.
ChemBioChem, 7, 1039-1047 (2006)
“Trimethylguanosine nucleoside inhibits cross-linking between Snurportin 1 and m3G-capped U1
snRNA”
Bahia, D., Aviñó, A., Eritja, R., Darzynkiewicz, E., Bach-Elías, M.
Nucleosides, Nucleotides & Nucleic Acids, 25, 909-923 (2006).
“Comparative uptake of phosphorothioate oligonucleotides by human peripheral blood
mononuclear cells from newborns and adults”
Bermejo, J.F., Chonco, L., Samaniego, R., Fernández, G., Eritja, R., Muñoz-Fernández, M.A.
Eur. J. Sci. Res., 15, 113-121 (2006).
“Water-soluble carbosilane dendrimers: Synthesis, biocompatibility and complexation with
oligonucleotides; evaluation for medical applications.”
Bermejo, J.F., Ortega, P., Chonco, L., Eritja, R., Samaniego R., Müllner, M., de Jesús, E., de la
Mata, F.J., Flores, J.C., Gómez, R., Muñoz-Fernández, A.
Chemistry, Eur. J., 13, 483-495 (2007).
“Spectroscopic study of the interaction of actinomycin D with oligonucleotides carrying the
central base sequences XGCY- and XGGCCY- using multivariate methods.”
Vives, M., Tauler, R., Eritja, R., Gargallo, R.
Anal. Bioanal. Chem., 387, 311-320 (2007).
“Solid-phase synthesis of modified oligonucleotides”.
Eritja R.
Int. J. Pept. Res. Ther., 13, 53-68 (2007).
“A flexible method for the fabrication of gold nanostructures using oligonucleotide derivatives”
Eritja, Aviñó, A., de la Torre, B.G., Fitzmaurice, D., Ongaro, A., Stanca, S.E., DiSalvo, A.,
Manning, B., Iacopino. D.
Nucleosides, Nucleotides & Nucleic Acids, 26, 1605-1609 (2007).
“Triplex formation using oliognucleotide clamps carrying 8-aminopurines”
Aviñó, A., Grimau, M.G., Alvira, M., Eritja, R., Gargallo, R., Orozco, M., González, C.

Nucleosides, Nucleotides & Nucleic Acids, 26, 979-983 (2007).
“New developments on the synthesis of oligonucleotide-peptide conjugates”
Portela, C., Mascareñas, J.L., Albericio, F., Mazzini, S., Caminal, C., Ramos, R., Ocampo, S.M.,
Eritja, R.
Nucleosides, Nucleotides & Nucleic Acids, 26, 963-967 (2007).
“Ds-Oligonucleotide-peptide conjugates featuring peptides from the leucine zipper region of fos
as switchable receptors for the oncoprotein Jun.”
Portela, C., Albericio, F., Eritja, R., Castedo, L., Mascareñas, J.L.
ChemBiochem, 8, 1110-1114 (2007).
“Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding
to serum proteins”.
Chonco, L., Bermejo-Martín, J.F., Ortega, P., Shcharbin, D., Pedziwiatr, E., Klajnert, B., Javier
de la Mata, F., Eritja, R., Gómez, R., Bryszewska, M., Muñoz-Fernández, M.A.
Org. Biomol. Chem., 5, 1886-1893 (2007).
”Analysis of interaction between dendriplexes and bovine serum albumin.”
Shcharbin, D., Pedziwiatr, E., Chonco, L., Bermejo-Martin, J., Ortega, P., de la Mata, F., Eritja,
R., Gómez, R., Klajnert, B., Bryszewska, M., Muñoz-Fernández, M. A.
Biomacromolecules, 8, 2059-2062 (2007).
“Synthesis of oligonucleotides carrying 5’-5’ linkages using copper-catalyzed cycloaddition
reactions”
Alvira, M., Eritja, R.
Chem. Biodivers., 4, 2798-2809 (2007).
“Solution equilibria of the i-motif-forming region upstream of the B-cell lymphoma-2 P1
promoter”
Khan, N., Aviñó, A., Tauler, R., Gonzalez, C., Eritja, R., Gargallo, R.
Biochimie, 89, 1562-1572 (2007).
“Synthesis of oligonucleotide derivatives using ChemMatrix supports”
Mazzini, S., García-Martín, Alvira, M., Aviñó, A., Manning, B., Albericio, F., Eritja, R.
Chem Biodivers., 5, 209-218 (2008).
“Incorporation of Zebularine from its 2’-deoxyribonucleoside triphosphate derivative and activity
as a template-coding nucleobase.”
Dowd, C.L., Sutch, B.T., Haworth, I.S., Eritja, R., Marquez, V.E., Yang, A.S.
Nucleosides, Nucleotides & Nucleic Acids, 27, 131-145 (2008).
“Solid-phase synthesis of oligomers carrying several chromophore units linked by
phosphodiester backbones”
Aviñó, A., Navarro, I., Farrera-Sinfreu, J., Royo, M., Aymamí, J., Delgado, A., Llebaria, A.,
Albericio, F., Eritja, R.
Bioorg. Med. Chem. Lett., 18, 2306-2310 (2008).

“Design, synthesis and antiproliferative properties of oligomers with chromophore units linked
by amide backbones”
Farrera-Sinfreu, J., Aviñó, A., Navarro, I., Aymamí, J., Beteta, N.G., Varón, S., Pérez-Tomás, R.,
Castillo-Avila, W., Eritja, R. , Albericio, F., Royo, M.
Bioorg. Med. Chem. Lett., 18, 2440-2444 (2008).
“8-aminoguanine accerelates tetramolecular G-quadruplex formation”
Gros, J., Aviñó, A., López de la Osa, J., González, C., Lacroix, L., Pérez, A., Orozco, M., Eritja,
R., Mergny, J.L.
Chem. Commun., 2926-2928 (2008)
“Study of the interaction between the G-quadruplex-forming thrombin-binding aptamer and the
porphyrin 5,10,15,20-tetrakis-(N-methyl-4-pyridyl)-21,23H-porphyrin tetratosylate”
Del Toro, M., Gargallo, R., Eritja, R., Jaumot, J.
Anal. Biochem., 379, 8-15 (2008)
“Synthesis of oligonucleotide conjugates carrying viologen and fluorescent compounds”
Alvira, M., Quinn, S.J., Aviñó, A., Fitzmaurice, D., Eritja, R.
The Open Org. Chem. J., 2, 41-45 (2008).
“Experimental measurement of carbohydrate aromatic stacking in water using a dangling-ended
DNA model system”.
Morales, J.C., Reina, J.J., Díaz, I., Aviñó, A., Nieto, P.M., Eritja, R.
Chemistry Eur. J., 14, 7828-7835 (2008).
“Synthesis and hybridization properties of modified oligodeoxynucleotides carrying non-natural
bases”.
Aviñó, A., Pérez-Rentero, S., Garibotti, A.V., Siddiqui, M.A., Márquez, V.E., Eritja R.
Chem. Biodivers., 6, 117-126 (2009).
“Photocleavage of peptides and oligodeoxynucleotides carrying 2-nitrobenzyl groups”.
Ramos, R., Manning, B., Aviñó, A., Gargallo, R., Eritja, R.
Helv. Chim. Acta, 92, 613-622 (2009).
“Label-free DNA biosensors based on functionalized carbon nanotube field effect transistors”.
Martínez, M.T., Tseng, Y.C., Ormategui, N., González-Domínguez, J.M., Loinaz, I., Eritja, R.,
Bokor, J.
Nano Lett., 9, 530-536 (2009).
“Classification of nucleic acids structures by means of the chemometric analysis of circular
dichroism spectra”.
Jaumot, J., Eritja, R., Navea, S., Gargallo, R.
Anal. Chim. Acta, 642, 117-126 (2009).
“Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference
studies”.

Aviñó, A., Ocampo, S. M., Caminal, C., Perales, J.C., Eritja, R.
Mol. Divers., 13, 287-293 (2009).
“DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-
(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site”.
van Bemmel, D.M., Brank, A. S., Eritja, R., Marquez, V.E., Christman, J.K.
Biochem. Pharmacol., 78, 633-641 (2009).
“Fluorescence site-encoded DNA addressable hapten-microarray for anabolic androgenic
steroids.”
Tort, N., Salvador, J.P., Eritja, R., Poch, M., Martínez, E., Samitier, J., Marco, M.P.
Trends Anal. Chem., 28, 718-728 (2009).
“Targeting the G–quadruplex forming region near the P1 promoter in the human BCL-2 gene
with the cationic porphyrin TMPyP4 and with the complementary C-rich strand.”
Del Toro, M., Bucek, P., Aviñó, A., Jaumot, J., González, C., Eritja, R., Gargallo, R.
Biochimie, 91, 894-902 (2009).
“Modified oligonucleotides for biosensing applications.”
Manning, B., Pérez-Rentero, S., Garibotti, A.V., Ramos, R., Eritja, R.
Sensor Lett., 7, 774-781 (2009).
“The use of conformationally rigid nucleoside probes to study the role of sugar pucker and
nucleobase orientation in the thrombin binding aptamer”.
Saneyoshi, H., Mazzini, S., Aviñó, A., Portella, G., González, C., Orozco, M., Marquez, V.,
Eritja, R.
Nucleic Acids Symp. Ser. (Oxford), 53, 109-110 (2009).
“α, γ-Peptide nanotube templating 1D parallel fullerene arrangements.”
Reiriz, C., Brea, R.J., Arranz, R., Carrascosa, J.L., Garibotti, A., Manning, B., Valpuesta, J.M.,
Eritja, R., Castedo, L., Granja, J.R.
J. Am. Chem. Soc., 131, 11335-11337 (2009).
“Assembly of two-dimensional DNA crystals carrying N 4 -[2-(tert-butyldisulfanyl)ethyl]-cytosine
residues.”
Garibotti, A.V., Sisquella, X., Martínez, E., Eritja R.
Helv. Chim. Acta, 92, 1466-1472 (2009).
“Unique tautomeric and recognition properties of thioketothymines?.”
Faustino, I., Aviñó, A., Marchán, I., Luque, F.J., Eritja, R., Orozco, M.
J. Am. Chem. Soc., 131, 12845-12853 (2009).
“pH-modulated Watson-Crick duplex- quadruplex equilibria of guanine-rich and cytosine-rich
DNA sequences 140 bp upstream of the c-kit transcription initiation site”.
Bucek, P., Jaumot, J., Aviñó, A., Eritja, R., Gargallo, R.
Chemistry Eur. J., 15, 12663-12671 (2009).

“Conformationally rigid nucleoside probes help inderstand the role of sugar pucker and
nucleobase orientation in the thrombin binding aptamer”.
Saneyoshi, H., Mazzini, S., Aviñó, A., Portella, G., González, C., Orozco, M., Marquez, V.,
Eritja, R.
Nucleic Acids Res., 37, 5589-5601 (2009).
“Triplex-stabilizing properties of parallel clamps carrying LNA derivatives at the Hoogsteen
strand”
Alvira, M., Eritja, R,
Chem. Biodivers., 7, 376-382 (2010).
“Fabrication of patterned surfaces by photolithographic exposure of DNA-hairpins carrying a
novel photolabile group.”
Manning, B., Leigh, S.J., Ramos, R., Preece, J., Eritja, R.
J. Exp. Nanoscience, 5, 26-39 (2010).
“Synthesis and structural properties of G,T-parallel clamps carrying 8-aminopurine residues.”
Aviñó, A., Cubero, E., Gargallo, R., González, C., Orozco, M., Eritja, R.
J. Nucleic Acids, vol. 2010, Article ID 763658, 11 pages. doi:10.4061/2010/763658 (2010).
“Stepwise synthesis of oligonucleotide-peptide conjugates containing guanidinium or lipophilic
groups in their 3’-termini”
Grijalvo, S., Terrazas, M., Aviñó, A., Eritja, R.
Bioorg. Med. Chem. Lett., 20, 2144-2147 (2010).
“Synthesis and G-quadruplex binding properties of defined acridine oligomers”
Ferreira, R., Aviñó, A., Pérez-Tomás, R., Gargallo, R., Eritja, R.
J. Nucleic Acids, vol. 2010, Article ID 489060, 10 pages, doi:10.4061/2010/489060 (2010).
”Thrombin binding aptamer quadruplex formation: AFM and voltammetric characterization”
Diculescu, V.C., Chiorcea-Paquim, A.M., Eritja, R., Oliveira-Brett, A.M.
J. Nucleic Acids, vol. 2010, Article ID 841932, 8 pages, doi:10.4061/2010/841932 (2010).
“Synthesis, cell-surface binding and cellular uptake of fluorescently labelled glucose-DNA
conjugates with different carbohydrate presentation”
Ugarte-Uribe, B., Pérez-Rentero, S., Lucas, R., Aviñó, A., Reina, J.J., Alkorta, I., Eritja, R.,
Morales, J.C.
Bioconjugate Chem., 21, 1280-1287 (2010).
“Modified siRNAs for the study of the PAZ domain”
Somoza, A., Terrazas, M., Eritja, R.
Chem. Commun., 46, 4270-4272 (2010).
“Synthesis and properties of oligonucleotides carrying isoquinoline imidazo[1,2-a]azine
fluorescente units”
Pérez-Rentero, S., Kielland, N., Terrazas, M., Lavilla, R., Eritja, R.
Bioconjugate Chem., 21, 1622-1628 (2010).

“Spectrometric study of the oligodeoxyribonucleotide protonation in aqueous solution”
Gargallo, R., Eritja, R., Kudrev, A.G.
Russ. J. Gen. Chem., 80, 485-492 (2010). English traslation
Zhurnal Obshchei Khimii, 80, 462-470 (2010). Original Russian Text
“Solid-phase synthesis of oligodeoxynucleotides carrying N 4 -[2-t-butyldisulfanyl)ethyl]-5methylcytosine“
Pérez-Rentero, S., Garibotti, A.V., Eritja, R.
Molecules, 15, 5692-5707 (2010).
”Development of a novel fluorescence assay based on the use of the thrombin binding aptamer
for the detection of O 6 -alkylguanine-DNA alkyltransferase activity”
Tintoré, M., Aviñó, A., Ruiz, F.M., Eritja, R., Fàbrega, C.
J. Nucleic Acids, vol. 2010, Article ID 632041, 9 pages, doi:10.4061/2010/632041 (2010).
“Synthesis of oligonucleotides carrying amino lípido groups at the 3’-end for RNA interference
studies”
Grijalvo, S., Ocampo, S.M., Perales, J.C., Eritja, R.
J. Org. Chem., 75, 6806-6813 (2010).
“G-quadruplex Nucleic Acids”
Eritja, R., Mergny, J.L., Montesarchio, D., Spindler, L., Webba da Silva, M.
J. Nucleic Acids, vol. 2010, Article ID 147650, 2 pages, doi:10.4061/2010/147650 (2010).
“Synthesis and structural properties of oligonucleotides covalently linked to acridine and
quindoline derivatives through a threoninol linker”
Aviñó, A., Mazzini, S., Ferreira, R., Eritja, R.
Bioorg. Med. Chem., 18, 7348-7356 (2010).
“Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues”
Terrazas, M., Eritja, R.
Mol. Divers., 15, 677-686 (2011).
“Chemical equilibria studies using multivariate analysis methods”
Jaumot, J., Eritja, R., Gargallo, R.
Anal. Bioanal. Chem., 399, 1983-1997 (2011).
“Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose
with different presentation”
Aviñó, A., Ocampo, S. M., Lucas, R., Reina, J. J., Morales, J. C., Perales, J. C., Eritja, R.
Mol. Divers., 15, 751-757 (2011).
“Synthesis of lipid-oligonucleotide conjugates for inhibition of gene expression”
Grijalvo, S., Ocampo, S. M., Perales, J. C., Eritja, R.
Chem. Biodivers., 8, 287-299 (2011).

“Highly polar carbohydrates stack onto DNA duplexes via CH/π interactions”
Lucas, R., Gómez-Pinto, I., Aviñó, A., Reina, J.J., Eritja, R., González, C., Morales, J.C.
J. Am. Chem. Soc., 133, 1909-1916 (2011).
“Effect of North bicyclo[3.1.0]hexane pseudosugars on RNA interferente. A novel class of
siRNA modification”
Terrazas, M., Ocampo, S.M., Perales, J.C., Marquez, V.E., Eritja, R.
ChemBioChem, 12, 1056-1065 (2011).
“Branched RNA: a new architecture for RNA interference”
Aviñó, A., Ocampo, S.M., Perales, J.C., Eritja, R.
J. Nucleic Acids, vol. 2011, Article ID 586935, 7 pages, doi:10.4061/2011/586935 (2011).
”Evaluation of the structure-activity relationship of thrombin binding aptamers by voltammetry
and atomic force microscopy”
Diculescu, V.C., Chiorcea-Paquim, A.M., Eritja, R., Oliveira-Brett, A.M.
J. Electroanal. Chem., 656, 159-166 (2011).
“Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer Gquadruplex
structures”
Ferreira, R., Artali, R., Farrera-Sinfreu, J., Albericio, F., Royo, M., Eritja, R., Mazzini, S.
Biochim. Biophys Acta, 1810, 769-776 (2011).
“Functionally enhanced siRNA targeting TNFα attenuates DSS-induced colitis and TLRmediated
immunostimulation in mice”
Ocampo, S.M., Romero, C., Aviñó, A., Burgueño, J., Gassull, M.A., Bermúdez, J., Eritja, R.,
Fernandez, E., Perales, J.C.
Mol. Ther., in press (2011).
“A direct, efficient method for the preparation of siRNAs containing ribo-like North
bicyclo[3.1.0]hexane pseudosugars”
Terrazas, M., Aviñó, A., Siddiqui, M., Marquez, V., Eritja, R.
Org. Lett., 13, 2888-2891 (2011).
“Synthesis of oligonucleotide-peptide conjugates for biomedical and technological applications”
Aviñó, A., Grijalvo, S., Pérez-Rentero, S., Garibotti, A., Terrazas, M., Eritja, R. Methods in
Molecular Biology, “Bioconjugation Protocols 2 nd edition”. (S. Mark Ed.) Humana Press,
Springer, New York, vol. 751, Part 2, pp 223-238 (2011).
“Influence of pH, temperature and the cationic porphyrin TMPyP4 on the stability of the i-motif
formed by the 5’-(C3TA2)4-3’ sequence of the human telomere”.
Fernández, S., Eritja, R., Aviñó, A., Jaumot, J. Gargallo, R.
Int. J. Biol. Macromol., 49, 729-736, (2011).
“Thrombin binding aptamer, more than a simple aptamer.: Chemically modified derivatives and
biomedical applications”.
Aviñó, A., Fàbrega, C., Tintoré, M., Eritja, R.

Curr. Pharm. Design, in press, (2011).
“Functionalization and self-assembly of DNA bidimensional arrays”.
Garibotti, A.V., Pérez-Rentero, S., Eritja, R.
Int. J. Mol. Sci., 12, 5641-5651, (2011).
“Preparation and AFM-characterization of self-assembled monolayers functionalized with a
thrombin binding aptamer”.
Manning, B., Gállego, I., Tintoré, M., Fàbrega, C., Aviñó, A., Eritja, R.
Int. Rev. Biophys. Chem., in press, (2011).
“Use of oligonucleotides carrying photolabile groups for the control of the deposition of
nanoparticles in surfaces and nanoparticle association”
Manning, B., Eritja, R.
Int. J. Mol. Sci., 12, 7238-7249, (2011).
“Functionalization of surfaces with synthetic oligonucleotides”
Manning, B., Eritja, R.
Methods in Molecular Biology, “Nanotechnology in Regenerative Medicine: Methods and
Protocols. (J.A. Planell, M. Navarro Eds.) Humana Press, Springer, New York, vol. 811, 89-100,
(2012).
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US20050014164-A1 (20 Jan 2005), AU2003285916-A8 (10 Nov 2005). Asignee: Cygene Inc.
“Target sequences for the detection of the West Nile virus”
Lopez, M.J., Eritja, R., Munzer, M.
Patent USA, WO2004042362-A2 (21 May 2004), US20040137431 (15 Jul 2004),
AU2003291765-A1 (07 Jun 2004). Asignee: Cygene Inc.
“Methods and compositions for blocking progression of a disease state”
Lopez, M.J., Eritja, R., Munzer, M.
Patent USA, WO2005025495-A2 (24 Mar 2005), US20050197305-A1, (08 Sep 05). Asignee:
Cygene Lab Inc.
“Methods and compositions for in vitro and in vivo use of parallel stranded hairpins and triplex
structures as nucleic acid ligands”
Lopez, M.J., Munzer, M., Eritja, R.
Patent USA, US20050089893-A1 (28 Apr 2005), WO2005067437-A2 (28 Jul 2005);
EP1730158-A2 (13 Dec 2006). Asignee: Cygene Inc.
“New Polymers and their use as fluorescent labels”
Aymamí, J., Albericio, F., Aviñó, A., Farrera, J., Royo, M., Navarro, I., Eritja, R.
European Patent, application 07112386.3-2101, 12.07.07, PCT/EP2008/058922, 09 July 2008.
US 2010129800(A1) 27.05.2010. Asignee: Crystax Pharmaceuticals S.L.
“Novel drugs for inhibition of gene expression”
Jimenez, A.I., Panizo, G., Martinez, T., Aviñó, A., Caminal, C., Eritja, R.
Patent England, application GB2009-10723, 22 June 2009. PCT, WO 20101500004, 22 June
2010.
Asignee: Sylentis S.A.U.
“Derivados lipofílicos de los ácidos nucleicos”
Eritja, R., Ocampo, S.M., Perales, J.C., Grijalvo, S., Aviñó, A.
Spanish patent, application Nº P201030611, 27 April 2010, PCT/ES2011/070293, 25 Abril 2011.
Asignee: CSIC, CIBER, Universidad de Barcelona

“Método para la administración de oligonucleótidos”
Eritja, R., Ocampo, S., Blasco, F. X., Perales, J. C.
Spanish patent, application Nº P201030629, 28 April 2010, PCT/ES2011/070295, 26 Abril 2011.
Asignee: CSIC, Universidad de Barcelona
“Oligonucleótidos modificados como reguladores de la expresión génica”
Somoza, A., Manning, B., Eritja, R., Terrazas, M., Ocampo, S. M., Aviñó, A., Perales, J.
Spanish patent, application Nº P201030614, 27 April 2010, PCT/ES2011/070296, 26 Abril 2011.
Asignee: CSIC, CIBER, Universidad de Barcelona
“Derivados de pequeños ARN de interferencia y su uso”
Romero, C., Ocampo, S., Eritja, R., Fernández, E., Perales, J.
Spanish Patent, application Nº P201031622, 4 November 2010, PCT/ES2011/070740, 26 Octubre
201.
Asignee: CSIC, Universidad de Barcelona, Universidad Autónoma de Barcelona
CONTRIBUTIONS IN SCIENTIFIC MEETINGS
"Utilización de la Nbb-resina en la síntesis de péptidos cíclicos." Giralt, E., Eritja, R., Josa, J.,
Navalpotro, C., Pedroso, E.
XIX Reunión Bienal de la Real Sociedad Espanola de Física y Química. Santander 1982.
"Use of Nbb-resin and 4-hydroxymethylphenoxymethyl-resin in solid phase synthesis."
Pedroso, E., Grandas, A., Eritja, R., Giralt, E.
17 European Peptide Symposium. Praga 1982.
"Solid phase synthesis of two segments: sequence 53-59 and 18-31 of the scorpion toxin II of
Androctonus australis Hector."
Van Rietschoten, J., Albericio, F., Tessier-Rochat, M., Granier, C., Grandas, A., Eritja, R.,
Pedroso, E., Giralt, E.
International Forum on Peptides. Le Cap D'Agde (Francia) 1984.
"Solid phase synthesis of two protected segments from the C-terminal region of Androctonus
australis Hector toxin II."
Giralt, E., Eritja, R., Grandas, A., Pedroso, E., Tessier, M., Albericio, F., Granier, C., Van
Rietschoten, J.
18 European Peptide Symposium. Suecia 1984.
"Convergent solid phase peptide synthesis."
Giralt, E., Eritja, R., Grandas, A., Nicolas, E., Josa, J., Pedroso, E., Tessier, M., Albericio, F.,
Granier, C., Van Rietschoten, J.
European Symposium of Organic Chemistry. Aix-en Provence (Francia) 1985.

"Conformational behaviour of nucleotides relevant to DNA replication fidelity." Goodman, M.F.,
Petruska, J., Sowers, L.C., Boosalis, M., Randall, S.K., Dalton, L., Mhaskar, D.N., Khwaja, T.,
Fazakerley, G.V., Eritja, R., Kaplan, B.E.
UCLA Symposia on Molecular & Cellular Biology. Colorado Springs (USA) 1986.
"Convergent solid phase peptide synthesis."
Giralt, E., Eritja, R., Grandas, A., Nicolas, E., Josa, J., Pedroso, E., Tessier, M., Albericio, F.,
Granier, C., Van Rietschoten, J.
3rd Mediterranean Congress on Chemical Engineering. Barcelona 1984.
"Convergent solid phase peptide synthesis: Recent progresses."
van Rietschoten, J., Sabatier, J-M., Tessier, M., Granier, C., Pedroso, E., Grandas, A., Albericio,
F., Eritja, R., Nicolas, E., Josa, J., Giralt, E., Protides of the Biological Fluids. Brussels
(Belgium) 1986.
"On the use of polystyrene as solid suport in oligodeoxyribo nucleotide synthesis."
Pedroso, E., Bardella, F., Eritja, R., Giralt, E.
4th International conference on polymer supported reactions in Organic Chemistry. Barcelona
1988.
"Gel-phase NMR spectroscopy a useful tool in solid phase synthesis."
Giralt, E., Albericio, F., Bardella, F., Eritja, R., Feliz, M., Pedroso, E., Pons, M., Rizo, J.
Innovations and perspectives in solid phase synthesis. Oxford 1989.
"Resonancia magnética nuclear en fase gel: Una técnica útil en síntesis sobre soporte
polimérico."
Giralt, E., Albericio, F., Bardella, F., Eritja, R., Feliz, M., Pedroso, E., Pons, M., Rizo, J.
Encuentro peptídico ibérico-2 (EPI-2). Cercedilla (Madrid) 1989.
"Synthesis of oligonucleotides containing 4-O-ethylthymidine."
Pedroso, E., Fernandez, D., Palom, Y., Eritja, R.
9th International Round Table. Nucleosides, nucleotides and their biological application. Uppsala
(Sweden) 1990.
"NPE-resin : a new approach for the synthesis of protected peptides and oligonucleotides."
Albericio, F., Robles, J., Fernandez, D., Palom, Y., Celma, C., Pedroso, E., Giralt, E., Eritja, R.
21th European peptide symposium. Barcelona (Spain) 1990.
"Synthesis of oligonucleotides containing biologically relevant base analogues."
Eritja, R., Fernandez, D., Palom, Y., Robles, J., Giralt, E., Pedroso, E.
8th Symposium on the Chemistry of Nucleic Acids Components. Bechnye (Txecoslovaquia)
1990.
"Oligonucleòtids sintètics en Biologia Molecular."
Eritja, R.
PEBEC-90: La Biotecnologia i la Sanitat. Barcelona (Spain) 1990.

“Deterninación del contenido de hidroxiprolina en el cuero”
Pons, A., Esteves, T., Pons, S., Eritja, R.
Congreso de la IUTCS, Barcelona, 1991.
"Solid-phase synthesis of protected peptides."
Albericio, F., Lloyd-Williams, P., Gairí, M., Jou, G., Eritja, R., Giralt, E.
12th American Peptide Symposium. Cambridge (USA) 1991.
"Biopolymer syntheses on novel polyethylene glycol-polystyrene (PEG-PS) graft supports."
Barany, G., Albericio, F.,Biancalana, S., Bontems, S.L., Chang, J.L., Eritja, R., Ferrer, M., Lyttle,
M.H., Solé, N., Tian, Z., Van Abel, R.J., Wright, P.B., Zalipsky, S., Hudson, D.
12th American Peptide Symposium. Cambridge (USA) 1991.
"Convergent solid-phase peptide synthesis."
Albericio, F., Lloyd-Williams, P., Gairí, M., Celma, C., Grandas, A., Eritja, R., Pedroso, E., van
Rietschoten, J., Barany, G., Giralt, E.
Innovations and Prespectives on Solid-phase synthesis II. Oxford. (England) 1991.
"Sintesis de híbridos péptido-oligonucleótidos que contienen una secuencia señal de transporte
nuclear."
Eritja, R., Pons, A., Escarceller, M., Aviñó, A., Acedo, M., Giralt, E., Albericio, F.
Encuentro peptídico ibérico-III. Leon (Spain) 1991.
"Nuevas estrategias de sintesis de peptidos con puentes disulfuro."
Royo, M., García-Echevaría, C.,Slomczynska, U., Eritja, R., Giralt, E., Albericio, F.
Encuentro peptídico ibérico-III. Leon (Spain) 1991.
"Effects of surrounding base sequence on nucleotide insertion, extension, and excision at abasic
DNA template sites."
Goodman, M.F., Cai, H., Bloom, L., Reha-Krantz, L., Eritja, R.
First multidisciplinary international symposium. The structure, biology and pharmacology of
abasic and related DNA sites.
Paris, France. April 1992.
"Preparation of oligonucleotides containing ammonia-sensitive nucleosides."
Eritja, R., Robles, J., Aviñó, A., Acedo, M., Albericio, F., Pedroso, E.
Tenth International Round Table: Nucleosides and Nucleotides.
Park City, Utah, USA. September 1992.
"Economic large-scale oligodeoxynucleotide synthesis by the phosphite-triester approach on
polystyrene."
Montserrat, X., Grandas, A., Eritja, R., Pedroso, E.
Tenth International Round Table: Nucleosides and Nucleotides.Park City, Utah, USA. September
1992.
"Strategies and tactics for the solid-phase synthesis of cysteine-containing peptides."

Albericio, F., Royo, M., Munson, M.C., Van Abel, R.J., Alsina, J., García-Echevarría, C.,
Slomczynska, U., Eritja, R., Pons, M., Giralt, E., Barany, G.
JASPEC'92. Japan 1992.
"Antisense oligodeoxynucleotides uptake into differentiating B cells."
Tarrason, G., Rodés, B., Eritja, R., Vilaró, S., Moyano, J.M., Piulats, J.
Fith International Congress on Cellular Biology.
Madrid, Spain. July 1992.
"Preparation of modified oligonucleotides containing base analogues of biological relevance."
Acedo, M., Aviñó, A., Cano, A., Fabrega, C., de la Torre, B. G., Eritja, R.
3rd Cambrigde Symposium "Synthetic Oligonucleotides and Analogues." Cambridge, England,
September 1993.
"Structural Kinetics of base excision from DNA with bacteriophage T4 polymerase."
Otto, M.R., Bloom, L.B., Eritja, R., Goodman, M.F., Beechem, J.M.
37 th Annual meeting of the Biophysical Society. Washington, USA, February 1993.
"Dynamics of DNA containing TATA box regions: a time resolved fluorescence study."
Otto, M.R., Bloom, L.B., Eritja, R., Goodman, M.F., Beechem, J.M.
37 th Annual meeting of the Biophysical Society. Washington, USA, February 1993.
"Structural kinetics and dynamics of deoxynucleotide excision from DNA by the bacteriophage
T4 polymerase."
Otto, M.R., Bloom, L.B., Reha-Krantz, L., Goodman, M.F., Beechem, J.M.
Joint Meeting of the American Society for Biochemistry and Molecular Biology and Division of
Biological Chemistry (ACS), San Diego, USA, June 1993.
"Use of a base-labile protected derivative of 6-mercaptohexanol for the preparation of
oligonucleotides containing a thiol group at the 5'-end."
de la Torre, B.G., Aviñó, A., Escarceller, M., Royo, M., Albericio, F., Eritja, R.
Innovations and Perspectives in solid phase synthesis, Oxford, England, September 1993.
"Utilización de grupos protectores derivados del feniletilo en síntesis de péptidos y
oligonucleótidos."
Eritja, R., Acedo, M., Aviñó, A., de la Torre, B.G., Fabrega, C., Albericio, F.
IV Encuentro Peptídico Ibérico, Gandia, Spain, November 1993.
"Observation of oligonucleotide dimers and trimers in electrospray mass spectrometry."
Abián, J., Gelpí, E., Eritja, R.
The 42nd ASMS Conference on mass spectrometry and allied topics.
Chicago, IL, USA, June 1994.
"Stepwise solid-phase synthesis of oligonucleotide-peptide hybrids."
de la Torre, B.G., Aviñó, A., Albericio, F., and Eritja, R.
23rd European Peptide Symposium , Braga, Portugal, September 1994.

"Preparation of oligonucleotides containing non-natural base analogues."
Eritja, R., Acedo, M., Aviñó, A., Fàbrega, M.
11 International Round Table on Nucleosides, Nucleotides and their biological applications,
Leuven, Belgium, September 1994.
"Biological activity of modified dodecamers directed against the point mutation in codon 12 of
the Ha-ras-mRNA."
Saison-Behmoaras, T., Duroux, I., Van Aershot, A., Eritja, R., Herdewijn, P., Hélène, C.
International Conference "Therapeutic oligonucleotides from cell to man". Seillac, France, April
1995.
"Platinum labelled oligonucleotides for X-ray crystallography: A Ligand, a Label, and a
Protecting Group."
Douglas, M.E., Eritja, R., Sproat, B.S.
Third Triennial International Meeting "Recognition studies on nucleic acids." Sheffield. April
1995.
"Synthesis and triple-helix formation of oligonucleotides containing 5-bromo-2'-deoxyuridine
and the side product 5-amino-2'-deoxyuridine."
Ramon Eritja, Elisenda Ferrer, Carme Fàbrega, Ramon Güimil García. "International Congress
on therapeutic oligonucleotides" Rome (Italy), June 9-12, 1996.
"N-Tritylamino acids. Synthesis and applications in solid-phase peptide synthesis."
dela Torre, B.G., Marcos, M.M., Alsina, J., Albericio, F., Eritja, R.
24th Symposium of the European Peptide Society, Edinburgh (Scotland) September 8-13, 1996.
"Introduction of macrocyclic 64Cu (II) and 99mTc ligands into nucleotides. A versatile approach
towards labeling antisense oligodeoxynucleotides for PET and SPECT tomography.
Wagner, S., Oberdorfer, F., Eisenhut, M., Eritja, R.
12 International RoundTable Nucleosides, Nucleotides and their biological applications, La Jolla,
September 15-19, 1996.
"Synthesis and properties of oligonucleotides containing 5-aza-2'-deoxycytidine."
Eritja, R., Marquez, V.E., Güimil García, R.
12 International RoundTable Nucleosides, Nucleotides and their biological applications, La Jolla,
September 15-19, 1996.
"Einführung makrozyklischer 64C(II)- und 99mTc-Liganden in Nukleotide."
Wagner, S., Oberdorfer, F., Eisenhut, M., Eritja, R.
4 Arbeitstagung of Arbeitsgemeinschaft Radiochemie / Radiopharmazie (DGN). Brielow-
Brandenburg (Alemania)17-19 de Octubre, 1996.
Preparation of oligonucleotides containing non-natural base analogs."
Eritja, R., Adam, V., Aviñó, A., Díaz, A.R., Fàbrega, C., Ferrer, E., Grøtli, M., Güimil García,
R., Hofmann, M., Márquez, V.E., Wiersma, M.
4th Swedish-German Symposium. Reisensburg Castle (Alemania). 23-26 November 1996.

"Automatisierte Konjugation von Makrozyklen an DNA und Tc99m Markierung."
Wagner, S., Oberdorfer, F., Eisenhut, M., Eritja, R.
35 Internationale Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin e.V. Kassel
(Germany) 16-19 April 1997.
"Preparation of modified oligonucleotides as tools for study DNA-Protein interactions.
Eritja, R., Díaz, A.R., Fàbrega, C., Ferrer, E., Hofmann, M., Güimil Gracía, R., Márquez, V.E.
4th New England Biolabs Workshop on Biological DNA modification. Innsbruck-Igls, 2-7
September 1997.
"DNA relaxases encoded by the streptococcal plasmid pMV158"
Espinosa, M., Moscoso, M., Guzman, L., Eritja, R., Grohmann, E., del Solar, G., Zechner, E.
Fundación JUAN MARCH, Madrid, October 1997.
"Preparación de oligonucleótidos que contienen 5-aza-2'-desoxicitidina."
Güimil García, R., Eritja, R.
Reunión de ácidos nucleicos y nucleósidos (RANN-1), Sitges, 17-18 October 1997.
"Síntesis y propiedades de oligonucleótidos que contienen derivados de las pirimidinas con
diversas substituciones en posición 5."
Ferrer, E., Eritja, R.
Reunión de ácidos nucleicos y nucleósidos (RANN-1), Sitges, 17-18 October 1997.
"Estudio de la implicación de la proteína S BP-2 en el cambio de isotipo de la
immunoglobulinas mediante la utilización de oligonucleótidos antisentido."
Tarrasón, G., Antón, P., Caparrós, F., Moyano, J.M., Eritja, R., Piulats, J.
Reunión de ácidos nucleicos y nucleósidos (RANN-1), Sitges, 17-18 October 1997.
"Modified oligonucleotides with triple-helix stabilization properties."
Eritja, R., Ferrer, E., Güimil García, R., Orozco, M.
13th International Round Table. Nucleosides, Nucleotides and their biological Applications.
Montpellier, 6-10 September 1998.
"Synthesis and triple helix stabilization properties of oligonucleotides containing 8aminopurines."
Eritja, R.
The Engelhardt Conference, Moscow, July 1999.
"Features of the CopG regulatory protein encoded by plasmid pMV158."
del Solar, G., Gomís-Rüth, F.X., Hernández-Arriaga, A.M., Acebo, P., Solà, M., Eritja, R., Coll,
M., Espinosa, M.
Gordon Conference, August 1999.
"Preparación de oligonucleótidos que contienen 8-aminopurinas y estudio de sus propiedades
estabilizadoras de hélices triples."
Eritja, R., Ferrer, E., Güimil García, R., Orozco, M.

Reunión sobre Ácidos Nucleicos y Nucleósidos. RANN-II
San Lorenzo del Escorial, Madrid. October 1999.
“Synthetic oligonucleotides as tools for the assembly of nanoparticles.”
Morales, J.C., Eritja, R., Doyle, H., Redmond, G.
6 th MELARI-NID Workshop, Enschede, The Netherlands, June 2000.
“Preparation and preclinical developments of tumor-targeting peptide-PNA conjugates”
Mier, W., Eritja, R., Mohammed, A., Haberkorn, U., Eisenhut, M.
Meeting of the Society of Nuclear Medicine, Toronto, Canada, June 2001.
“La estrategía antisentido desde una prespectiva química”
Eritja, R.
I Reunón de la Sociedad Española de Terapia Génica (SETG), Valencia, February 2001
“Synthesis of modified oligonucleotides with potential use on molecular electronics”
Eritja, R., de la Torre, B.G., Frieden, M., Aviñó, A.
8 th MEL-ARI/NID workshop, Würburg, Germany, July 2001
“Utilización de oligonucleótidos en electrónica molecular”
Eritja, R., de la Torre, B.G., Morales, J.C., Iacopino, D., Ongaro, A., Fitzmaurice, D., Doyle, H.,
Murphy, D., Redmond, G.
Reunión sobre Ácidos Nucleicos y Nucleósidos RANN-III,
Santiago de Compostela, Spain. July 2001.
“Síntesis de oligómeros de PNA con marcadores utilizando una metodología de modificación
post-sintética.”
De la Torre, B.G., Eritja, R.
VIII Encuentro Peptídico Ibérico, Barcelona. Spain. February 2002.
“Self-assembled and self-organization of DNA-templated nanoparticle architectures at patterned
silicon substrates and their metallization”
Ongaro, A., Iacopino, D., Fitzmaurice, D., Harnack, O., Ford, W., Yasuda, A., Wessels, J., Eritja,
R.
10 th MEL-ARI/NID workshop, Helsinki, Finland, July 2002.
“Properties of triple helices formed by oligonucleotides containing 8-aminopurines”
Aviñó, A., Frieden, M., Morales, J.C., de la Torre, B.G., Güimil-García, R., Orozco, M.,
González, C., Eritja, R.
XV International Round Table on Nucleosides, Nucleotides and Nucleic Acids. Leuven,
Belgium, September 2002.
“Requirement of U5 penultimate cytosine and glutamine 148 for strand transfer by HIV-1
integrase”
Johnson, A.A., Marchand, C., Karki, R.G., Nicklaus, M., Siddiqui, M.A., Eritja, R., Marquez,
V., Pommier, Y.
Research Festival 2002, N.I.H., Bethesda. USA. October 15-18, 2002.

“Oligonucleotide-nanoparticle conjugates as tools for nanoscale genetic analysis”
Murphy, D., Eritja, R., Redmond, G.
11 th MEL-ARI/NID workshop, Toulouse, 5-7 February 2003.
“Síntesis y evaluación de las propiedades antivirales de ácidos nucleicos peptídicos (PNA)”
Fortes, P., Berraondo, P., de la Torre, B.G., Razquin, N., Vales, A., Cuevas, Y., Aseguinolaza,
G., Ruiz, J., Eritja, R.
2ª Meeting of the Spanish Society of Gene Terapy, Barcelona, March 2003.
“DNA-mediated assembly of carbon nanotube devices”
Williams, K.A., Veenhuizen, P.T.M, Dekker, C., de la Torre, B.G., Eritja R., de Koning, M., and
Overhand, M.
E-MRS Spring Meeting 2003. Strasbourg (France), June 10-13, 2003.
“Ensamblaje de nanomateriales dirigido por derivados sintéticos del ADN”
de la Torre, B.G., Murphy, D., Redmond, G., Eritja, R.
IV Reunión de ácidos nucleicos y nucleósidos, Granada, Spain, November 2003.
“Síntesis de oligonucleótidos ramificados”
Grimau, M.G., Aviñó, A., Eritja, R.
IV Reunión de ácidos nucleicos y nucleósidos, Granada, Spain, November 2003.
“Triples helices antiparalelas”
Cubero, E., Aviñó, A., González, C., Eritja, R., Orozco, M.
IV Reunión de ácidos nucleicos y nucleósidos, Granada, Spain, November 2003.
“Towards the selective recognition of the oncogenic protein jun : design and synthesis of
conjugates between the leucine rich regions of fos and oligonucleotides”
Portela, C., Albericio, F., Eritja, R., Mascareñas, J.L.
Encuentro peptídico ibérico, Oporto, January 2004.
“Assembly of nanomaterials directed by oligonucleotide derivatives.”
Eritja, R., de la Torre, B.G., Aviñó, A., Gutiérrez, M.G., Iacopino, D., Ongaro, A., Fitzmaurice,
D. Murphy, D., Redmond, G.
1 st NanoSpain Workshop, San Sebastian, March 2004.
“Gold nanoparticles as tracers for oligonucleotide-peptide conjugates”
Aldavert, M., Tarrasón, G., Eritja, R., Merkoçi, A., Alegret, S.
IX Transfrontier Meeting on Sensors and Biosensors, Tarragona, Spain. September 2004
“DNA-templated assembly of nanoscale architectures for next-generation electronic devices.”
Stanca, S.E., Eritja, R., Fitzmaurice, D.
RSC conference on Molecular wires and nanoscale conductors. Manchester. September 2005.
“Síntesis de conjugados oligonucleótido-péptido para la inhibición de la oncoproteína Jun”
Portela, C., Eritja, R., Albericio, F., Mascareñas, J.L.

XXX Reunión Bienal de la Real Sociedad Española de Química, Lugo, September 2005.
Síntesis, purificación y caracterización de oligonucleótidos cíclicos
Grimau, M.G., Eritja, R.
V Reunión de ácidos nucleicos y nucleósidos, Alcalá de Henares, Madrid, Spain. October 2005.
“Resolución de la competición estructural G-cuáduplex / dúplex”
Jaumot, J., Tauler, R., Eritja, R., Gargallo, R.
V Reunión de ácidos nucleicos y nucleósidos, Alcalá de Henares, Madrid, Spain, October 2005.
“Use of triplex-forming antiparallel purine-hairpins to produce strand displacement of doublestranded
DNA in gene repair studies”
Coma, S., Noé, V., Eritja, R., Ciutat, C.J.
V Reunión de ácidos nucleicos y nucleósidos, Alcalá de Henares, Madrid, October 2005.
“Síntesis de conjugados oligonucleótido-péptido derivados de la cremallera de leucinas de Fos
para la inhibición de la oncoproteína Jun”
Portela, C., Eritja, R., Albericio, F., Mascareñas, J.L.
V Reunión de ácidos nucleicos y nucleósidos, Alcalá de Henares, Madrid, October 2005.
“Un método para la captura específica de RNA utilizando oligonucleótidos formadores de
triplex”
Eritja, R., Aviñó, A., Ocampo, S.M., Perales, J.C., Orozco, M., Nadal, A., Coll, A., Pla, M.
II meeting of Ribonet, Barcelona, June 2006.
“A flexible method for the fabrication of gold nanostrucutures using oligonucleotide derivatives”
Eritja, Aviñó, A., de la Torre, B.G., Fitzmaurice, D., Ongaro, A., Stanca, S.E., DiSalvo, A.,
Manning, B., Iacopino. D.
XVII IRT on Nucleosides, Nucleotides and Nucleic Acids, Bern, September2006.
“Triplex formation using oliognucleotide clamps carrying 8-aminopurines”
Aviñó, A., Grimau, M.G., Alvira, M., Eritja, R., Gargallo, R., Orozco, M., González, C.
XVII IRT on Nucleosides, Nucleotides and Nucleic Acids, Bern, September 2006.
“New developments on the synthesis of oligonucleotide-peptide conjugates”
Portela, C., Mascareñas, J.L., Albericio, F., Mazzini, S., Caminal, C., Ramos, R., Ocampo, S.M.,
Eritja, R.
XVII IRT on Nucleosides, Nucleotides and Nucleic Acids, Bern, September 2006.
“Synthesis and properties of oligonucleotide-gold nanoparticle conjugates”
Eritja, R.
ASEVA Summer School, WS-19 Physical and chemical properties of nanoclusters, Ávila,
September 2006.
“Ds-Oligonucleotide-peptide conjugates featuring peptides from the leucine zipper region of c-
Fos as a new type of Jun receptors.”
Portela, C., Eritja, R., Albericio, F., Mascareñas, J.L.

CNIO Cancer Conference on Medicinal Chemistry in Oncology, Madrid, 2-4 Octubre 2006.
“First characterization of a biosensor for large DNA molecules using quartz crystal microbalance
and impedance spectroscopy”
Marques de Oliveira, I.A., Santos, M., Rodriguez, S., Eritja, R., Samitier, J. Errachid, A.
Transducers’07, Lyon, Francia. June 2007.
“Immobilization of DNA on silicon nitride by microcontact printing: Characterization of DNA-
IS sensors by Atomic Force Microscopy and Impedance Spectroscopy methods”
Caballero, D., Marques de Oliveira, I.A., Baccar, Z.M., Mazzouz, Z., Eritja, R., Zine, N.,
Samitier, J., Errachid, A.
XIXth International Symposium on Bioelectrochemistry and Bioenergetics, Toulouse, Francia,
April 2007.
“Synthesis of modified RNA to control gene expression by the mechanism of RNA interference”
Caminal, C., Aviñó, A., Ocampo, S., Perales, J.C., Eritja, R.
3rd Nucleic Acid Chemistry and Biology (NACB) Symposium, Odense, Denmark. 27-28 June
2007.
“Synthesis of oligonucleotides and oligonucleotide-peptide conjugates using ChemMatrix
supports”
Mazzini, S., García-Martin, F., Aviñó, A., Alvira, M., Albericio, F., Eritja, R.
3rd Nucleic Acid Chemistry and Biology (NACB) Symposium, Odense, Denmark. 27-28 June
2007.
“Synthesis of oligonucleotides carrying azido and alkynyl groups at the 5’-ends and their use in
Huisgen’s 1,3-dipolar cycloaddition reactions”
Alvira, M., Eritja, R.
3rd Nucleic Acid Chemistry and Biology (NACB) PhD Summer School, Odense, Denmark. 24-
28 June 2007.
“Efficacy and versatility of ChemMatrix resin”
Tulla-Puche, J., García-Martín, F., Marani, M.M., Paradís-Bas, M., García-Ramos, Y., de
Oliveira, E., Camperi, S.A., Cascone, O., Côte, S., Eritja, R., Albericio, F.
20 th American Peptide Symposium, Montreal, Canada, June 26-30, 2007.
“Gold Nanoparticles in DNA biosensors”
Castañeda, M.T., Eritja, R., Maltez, M.M.V., Alegret, S., Mercoçi, A.
Summer School on Women-in-Nano: Career Development and Research Trends, Coma-Ruga,
Tarragona, June 2007.
“The use of surface modification techniques to fabricate nanostructures at the wafer and
subwafer-scale”
Tunnicliffe, D.L., Quinn, A.J., Redmond, G., Preece, J.A., Jonas, U., Eritja, R., Tune, D.
Novel Applications of Surface Modification (NASM07), Southampton, UK, September 2007.

“Study of the interaction between the porphyrin TmPyP4 and the Thrombin Binding Aptamer
(TBA) G-quadruplex”
Del Toro, M., Eritja, R., Gargallo, R., Jaumot, J.
Euroanalysis XIV, Antwerp, Belgium, 9-14 September 2007.
“Synthesis of modified RNA to inhibit gene expresión in vitro”
Ocampo, S.M., Caminal, C., Aviñó, A., Perales, J.C., Eritja, R.
4th Annual RNAi Europe conference, Barcelona, 19-21 September 2007.
“Use of synthetic DNA for the assembly of nanostructures”
Eritja, R., Garibotti, A., Manning, B., Ramos, R., Aviñó, A., Alvira, M., Leigh, S., Preece, J.
IBEC Bioengineering and Nanomedicine Symposium ’07, Barcelona, 7 November 2007.
“Recent advances on DNA nanotechnology”
Eritja, R., Garibotti, A., Manning, B., Ramos, R., Aviñó, A., Gargallo, R., Tort, N., Salvador,
J.P., Marco, M.P., Poch, M., Martínez, E., Samitier, J., Leigh, S., Preece, J.
Sexta reunión de Ácidos Nucleicos y Nucleótidos (RANN-VI), Valencia, 22-23 November 2007.
“Synthesis of oligonucleotides carrying azido and alkynyl groups at the 5’-end and their use in
Huisgen’s 1,3-dipolar cycloaddition reactions.
Alvira, M., Eritja R.
Sexta reunión de Ácidos Nucleicos y Nucleótidos (RANN-VI), Valencia, 22-23 November 2007.
“Synthesis of poly-(DNA-intercalating)chromophores”
Aviñó, A., Navarro, I., Farrera, J., Royo, M., Aymamí, J., Albericio, F., Eritja, R.
Sexta reunión de Ácidos Nucleicos y Nucleótidos (RANN-VI), Valencia, 22-23 November 2007.
“Solution equilibria of the i-motif-forming region upsteam of the B-cell lymphoma-2 P1.
Gargallo, R., Khan, N., Aviñó, A., Tauler, R., Gonzalez, C., Eritja, R.,
Sexta reunión de Ácidos Nucleicos y Nucleótidos (RANN-VI), Valencia, 22-23 November 2007.
“Development of DNA/LDH hybrid nanomaterials for Biosensor application. Characterisation of
surface, morphology and impedance spectroscopy of DNA-IS sensors.”
Baccar, Z.M., Marques de Oliveira, I.A., Caballero, D., Eritja, R., Zine, N., Samitier, J., Errachid,
A.
12th European Conference on the Spectroscopy of Biological Molecules (ECSBM07), Bobigny,
Paris, France, September 1-6, 2007.
“Développement d’une nouvelle technique de fonctionnalisation de surface pour les biocapteurs :
Elaboration de biomembranes hybrides HDL/ADN. Etude des performances des biocapteurs
d’ADN.”
Baccar, Z.M., Eritja, R., Zine, N., Samitier, J., Errachid, A.
3rd International workshop on Biosensors for food safety and environmental monitoring. Fez,
Marroco, October 18-20, 2007.
“Use of DNA derivatives in nanosciences.”
Eritja R., Garibotti A., Aviñó A., Manning B., Alvira M., Ramos, R.

Nanobiosensors for biomedical applications (Nanoaracat), Bellaterra, Barcelona, Spain,
December 19-20, 2007.
“DNA sensors based on nanoparticles.”
Castaneda, M.T., Eritja, R., Maltez, M.M.V., Alegret, S., Merkoçi, A.
Nanobiosensors for biomedical applications (Nanoaracat), Bellaterra, Barcelona, Spain,
December 19-20, 2007.
“Electronic detection of biomolecules by carbon nanotube field effect transistors.”
Martínez, M.T., Tseng, Y.C., Bokor, J., Loinaz, I., Eritja, R., Marco, M.P., Salvador, J.P.
Nanobiosensors for biomedical applications (Nanoaracat), Bellaterra, Barcelona, Spain,
December 19-20, 2007.
“Use of DNA derivatives in nanosciences.”
Eritja R., Garibotti A., Aviñó A., Manning B., Alvira M., Ramos, R.
11 Encuentro Peptídico Ibérico (EPI-11), Santiago de Compostela, Spain, March, 6-7, 2008.
“Electronic detection of DNA hybridization”
Martínez, M.T., Tseng, Y.C., Bokor, J., Loinaz, I., Eritja, R.
NanoSpain 2008, Braga (Portugal) April 14-18, 2008.
“Studying the solution equilibria of G-quadruplex region upstream of the B-cell lyphoma-2 P1 by
means of multivariate data analysis methods.”
Del Toro, M., Jaumot, J., Aviñó, A., Eritja, R., Gargallo, R.
11th conference on chemometrics in Analytical Chemistry (CAC2008), Montpellier, France, 30
June - 4 July 2008.
“Classification of DNA structures by means of chemometrical methods”
Jaumot, J., del Toro, M., Gargallo, R, Eritja, R.
11th conference on chemometrics in Analytical Chemistry (CAC2008), Montpellier, France, 30
Junio - 4 Julio 2008.
“Potency in vitro of chemically modified siRNAs against TNF-α”
Ocampo, S.M., Aviñó, A., Grijalvo, S., Perales, J.C., Eritja, R.
RNAi Europe, Stockholm (Sweden), 16-18 September 2008.
“Spectoscopic study of non-canonical DNA structures using advanced chemometrics methods.”
Bucek, P., Vojtyloa, T., Gargallo, R., Lubal, P., Táborský, P.
XIXth Slovak-Czech spectroscopic conference, Casta-Papiernicka (Slovakia), 12-16 October,
2008.
“Foctionnalisation de surface des nitrure de silicium par microcontact printing pour la detection
d’ADN”
Caballero, D., Mazzouz, Z.; Baccar, Z.M., Eritja, R., Zine, N., Errachid, A., Kalfat, R., Sakly, M.
6 eme Journees Maghreb-Europe, MADICA 2008, Rabat (Maroc) 30 Oct-1 Nov. 2008.
“Use of DNA derivatives in the fabrication of devices and sensors”

Eritja, R., Garibotti, A., Aviñó, A., Manning, B., Alvira, M., Ramos, R., Pérez-Rentero, S.,
Grijalvo, S., Somoza, A.
6 eme Journees Maghreb-Europe, MADICA 2008, Rabat (Maroc) 30 Oct-1 Nov. 2008.
“An electrochemical biosensor based on impedance measurement for the detection of the DNA
hybridization”
Marques de Oliveira, I.A., Eritja, R., Samitier, J., Errachid, A.
6 eme Journees Maghreb-Europe, MADICA 2008, Rabat (Maroc) 30 Oct-1 Nov. 2008.
“Synthesis and structural characterization of SELEX-derived RNA aptamers by multidimensional
NMR spectroscopy”
Ragg, E.M., Mazzini, S., Tagliabue, A., Bellucci, M.C., Aviñó, A., Eritja, R.
8 th Italian Meeting on Natural Products, NAT8, Forte dei Marmi (Italy) 23-25 May 2009.
“Modified siRNAs and biocompatible gold nanoparticles”
Somoza, A., Manning, B., Terrazas, M., Eritja, R.
VII Reunión de ácidos nucleicos y nucleósidos, Jaca, Huesca, Spain. 10-12 June 2009.
“pH-modulated Watson-Crick duplex-quadruplex equilibria of guanine-rich and cytosine-rich
DNA sequences upstream of the c-kit transcription initiation site”
Buceck, P., Jaumot, J., Aviñó, A., Eritja, R., Gargallo, R.
VII Reunión de ácidos nucleicos y nucleósidos, Jaca, Huesca, Spain. 10-12 June 2009.
“Use of DNA-hairpins carrying photolabile groups in the fabrication of patterned surfaces by
photolithography”
Manning, B.J., Leigh, S., Perez, S., Ramos, R., Aviñó, A., Preece, J.A., Eritja, R.
VII Reunión de ácidos nucleicos y nucleósidos, Jaca, Huesca, Spain. 10-12 June 2009.
“Antiviral and biological properties of glucose-conjugated antisense oligodeoxynucleotides that
inhibit HIV-1 replication in cell culture”
Reyes-Darias, J.A., Sánchez-Luque, F.J., Eritja, R., Perez, S., Morales, J.C., Romero-López, C.,
Marton-García, S., Agustin Vacas, V., Berzal-Herranz, A.
VII Reunión de ácidos nucleicos y nucleósidos, Jaca, Huesca, Spain. 10-12 June 2009.
“Carbohydrate-oligonucleotide conjugates: how sugars other than (deoxy-)ribose affect DNA
stability and allow to study intermolecular forces”
Reina, J.J., Lucas, R., Aviñó, A., Gómez-Pinto, I., Díaz, I., Nieto, P.M., González, C., Eritja R.,
Morales, J.C.
VII Reunión de ácidos nucleicos y nucleósidos, Jaca, Huesca, Spain. 10-12 June 2009.
“Binding of anticancer agents to DNA investigated using optical tweezers”
Camuñas, J., Bizarro, C.V., Parts, E., Sisquella, X., Mata, A., Albericio, F., Eritja, R., Dev, S.B.,
Ritort, F.
Biophysics school, Urbana (Illinois), USA. 10-12 June 2009.
“Study of internalization of nucleic acid based bioconjugates”
Ugarte, B., Alonso, A., Goñi, F.M., Morales, J.C., Eritja, R., Berzal-Herranz, A., Alkorta, I.

34th FEBS Congress. Prague, Txec Republic. 4-9 July 2009.
“The use of photolabile oligonucleotides to fabricate patterned surfaces.”
Manning, B., Ramos, R., Leigh, S.J., Preece, J., Eritja, R.
Trends in Nanotechnology 2009 (TNT 2009), Barcelona, Spain, 7-11 September 2009.
“Fluorescence and SPR microarrays based on hapten-oligonucleotide bioconjugates.”
Tort, N., Pablo-Salvador, J., Aviñó, A., Eritja, E., Comelles, J., Martínez, E., Samitier, J., Marco,
M.P.
XXXII Annual Meeting of the Real Sociedad Española de Química, Oviedo, 13-18 September
2009.
“Tail-clamp modified DNA receptors for sensitive evaluation of DNA triple-helices by SPR
biosensing”
Carrascosa, L.G., Aviñó, A., Nadal, A., Plà, M., Eritja, R., Lechuga, L. M.
Europtrode, X conference on optical chemical sensors and biosensors, Prague, 28-31 March
2010.
“Novel ODN-conjugates for the inhibition of gene expression”
Grijalvo, S., Aviñó, A., Ocampo, S., Terrazas, M., Perales, J.C., Eritja, R.
III Jornadas CIBER-BBN, Barcelona, 6-7 May de 2010.
“Bidimensional DNA templates for surface functionalization”
Garibotti, A.V., Manning, B., Pérez-Rentero, S., Eritja, R.
3rd IBEC Symposium on Bioengineering and Nanomedicine, Barcelona, 1-2 June 2010.
“Synthesis of oligonucleotide-peptide conjugates for inhibition of gene expression”
Grijalvo, S., Aviñó, A., Terrazas, M., Ocampo, S., Perales, J.C., Eritja, R.
IRT2010, Lyon (France), 29 August-3 September 2010.
“Synthesis and applications of modified oligonucleotides for triplex and quadruplex formation”
Alvira, M., Aviñó, A., Fàbrega, C., Tintoré, M., Ferreira, R., Mazzini, S., Eritja, R.
IRT2010, Lyon (France), 29 August-3 September 2010.
“Effect of conformationally restricted pseudosugars on RNA interference. A novel class of
siRNA modification”
Terrazas, M., Márquez, V.E., Eritja, R.
IRT2010, Lyon (France), 29 August-3 September 2010.
“Carbohydrate-oligonucleotide conjugates: energetic probes to study interactions and cell
entrance varying sugar presentation”
Lucas, R., Gómez-Pinto, I, Ugarte-Uribe, B., Pérez-Rentero, S., Aviñó, A., Reina, J.J., Eritja, R.,
Alkorta, I., Gonzalez, C., Morales, J.C.
IRT2010, Lyon (Francia), 29 Agosto-3 September 2010.
“Bidimensional DNA templates for surface functionalization”
Garibotti, A.V., Manning, B., Pérez-Rentero, S., Eritja, R.

IRT2010, Lyon (France), 29 August-3 September 2010.
“Carbohydrate-oligonucleotide conjugates: energetic probe to study carbohydrate-aromatic
stacking in aqueous media”
Lucas, R., Gómez-Pinto, I., Aviñó, A., Reina, J.J., Eritja, R., González, C., Morales, J.C.
X Jornadas de carbohidratos, Granada, 15-18 September 2010.
“Carbohydrate-oligonucleotide conjugates: cellular uptake depending on glucose presentation”
Ugarte-Uribe, B., Pérez-Rentero, S., Lucas, R., Aviñó, A., Reina, J.J., Alkorta, I., Eritja, R.,
González, C., Morales, J.C.
X Jornadas de carbohidratos, Granada, 15-18 September 2010.
“Synthesis and applications of modified thrombin-binding aptamers”
Aviñó, A., Fàbrega, C., Tintoré, M., Ferreira, R., Mazzini, S., Eritja, R.
Guanosines and quadruplexes, Cost action MP0802 annual meeting, London, 15-17 September
2010.
“Applications of diffussion NMR to G-quadruplex characterization”
Kazlauskaite, U., Gaspariunaite, V., Kiseviciute, S., Aviñó, A., Eritja, R., Webba da Silva, M.,
Groves, P.
Guanosines and quadruplexes, Cost action MP0802 annual meeting, London, 15-17 September
2010.
“Highly polar carbohydrates stack onto DNA Watsin-Crick base-pairs and guanine tetrads via
CH/π interactions”
Gómez-Pinto, I., Lucas, R., Aviñó, A., Reina, J.J., Eritja, R., González, C. Morales, J.C.
V Biannual meeting of GERMN (RSEQ) - II Iberian meeting on NMR. Bilbao, 26-29 September
2010.
“Synthesis of modified siRNA to inhibit gene expression”
Eritja, R.
EuroTIDES 2010, invited speaker, Barcelona, 17-18 November 2010.
“Thrombin structure-activity relationship with thrombin binding aptamers by voltammetry and
atomic force microscopy”
Oliveira-Brett, A.M., Diculescu, V.C., Chiorcea-Paquim, A.M., Eritja, R.
XXI International Symposium on Bioelectrochemistry and Bioenergetics. Cracow, Polonia, 8-12
Mayo 2011, Poster.
“DNA bidimensional assemblies”
Manning, B., Garibotti, A., Pérez-Rentero, S., Gállego, I., Eritja, R.
XI Congreso de la Sociedad Española de Biofísica, invited speaker. Murcia 1-4 June 2011.
“Oligonucleótidos modificados en nanotecnología”
Somoza, A., Delgado, J.L., Bouit, P.A., Aviñó, A., Ares, P., Goméz-Herrero, J., Zamora, F.,
Eritja, R., Martín, N.
XI Congreso de la Sociedad Española de Biofísica. Murcia 1-4 June 2011.

“Interacción de carbohidratos con cúadruplex de guaninas”
Vengut, E., Gómez-Pinto, I., Lucas, R., Aviñó, A., Reina, J.J., Eritja, R., González, C., Morales,
J.C.
XI Congreso de la Sociedad Española de Biofísica. Murcia 1-4 June 2011.
“Exploration of biologically relevant binding motifs using carbohydrate oligonucleotide
conjugates”
Lucas, R., Gómez-Pinto, I., Aviñó, A., Vengut, E., Reina, J.J., Eritja, R., González, C., Morales,
J.C.
XI Congreso de la Sociedad Española de Biofísica. Murcia 1-4 June 2011.
“Structural studies on modified nucleic acids”
Martín-Pintado, N., Gómez-Pinto, I., Aviñó, A., Eritja, R., Damha, M., González, C.
XI Congreso de la Sociedad Española de Biofísica. Murcia 1-4 June 2011.
“Effect of North bicyclo[3.1.0]hexane pseudosugars on RNA interference: a novel class pf
siRNA modification”
Terrazas, M., Aviñó, A., Siddiqui, M.A., Ocampo, S.M., Perales, J.C., Márquez, V.E., Eritja, R.
8ª reunión de ácidos nucleicos y nucleósidos (RANN-VIII). Sevilla 9-10 July 2011.
“Strong interstrand interactions on DNA duplexes modified by single TTF units at the 3’ or 5’end”
Pérez-Rentero, S., Somoza, A., Ferreira, R., Janousek, J., Belohradsky, M., Stara, I.G., Starý, I.,
Eritja, R.
8ª reunión de ácidos nucleicos y nucleósidos (RANN-VIII). Sevilla 9-10 July 2011.
“Synthesis and properties of modified thrombin binding aptamers”
Aviñó, A., Mazzini, S., Portella, G., González, C., Orozco, M., Márquez, V.E., Eritja, R.
8ª reunión de ácidos nucleicos y nucleósidos (RANN-VIII). Sevilla 9-10 July 2011.
“Structural studies on modified nucleic acids and their complexes”
Martín-Pintado, N., Gómez-Pinto, I., Laurents, D.V., Aviñó, A., Campos, R., Portella, G.,
Orozco, M., Eritja, R., Damha, M., González, C.
8ª reunión de ácidos nucleicos y nucleósidos (RANN-VIII). Sevilla 9-10 July 2011.
“Synthesis of oligonucleotide-peptide conjugates for gene silencing experiments”
Grijalvo, S., Aviñó, A., Terrazas, M., Eritja, R.
Challenges in Organic and Bioorganic Chemistry. 12th Tetrahedron Symposium. Sitges, 21-24
June, 2011.
“DNA origami containing the thrombin binding aptamer”
Manning, B., Fabrega, C., Tintoré, M., Aviñó, A., Eritja, R., Gállego, I.
Third international meeting on G-quadruplex and G-assembly. Sorrento (Italy) 28 June-1 July,
2011.

“Study of chemical equilibria involving G-quadruplex and i-motifs by means of spectroscopic
techniques and multivariate data analysis methods”
Manaye, S., Jaumot, J., Eritja, R., Gargallo, R.
Third international meeting on G-quadruplex and G-assembly. Sorrento (Italy) 28 June-1 July,
2011.
“Evaluation of the structure-activity relationship of thrombin with thrombin binding aptamers by
voltammetry and atomic force microscopy”
Oliveira-Brett, A.M., Chiorcea-Paquim, A.M., Eritja, R., Diculescu, V.C.
Third international meeting on G-quadruplex and G-assembly. Sorrento (Italia) 28 June-1 July,
2011. Poster.
“8-amino guanines stabilize an interlocked G-quadruplex dimer”
Martin-Pintado, N., Aviñó, A., Eritja, R., González, C.
Third international meeting on G-quadruplex and G-assembly. Sorrento (Italia) 28 June-1 July,
2011. Poster.
“Exploration of biologically relevant binding-motifs using carbohydrate DNA conjugates”
Morales, J.C., Lucas, R., Gómez-Pinto, I., Aviñó, A., Vengut, E., Reina, J.J., Eritja, R.,
González, C.
XXXIII Reunión Bienal de la RSEQ. Valencia 25-28 Julio 2011. Comunicación Oral.
“Oligonucleótidos modificados en nanotecnología”
Somoza, A., Latorre, A., Delgado, J.L., Bouit, P.A., Aviñó, A., Eritja, R., Martín, N.
XXXIII Reunión Bienal de la RSEQ. Valencia 25-28 Julio 2011. Poster.
“Interacción de carbohidratos con cúadruplex de guaninas”
Vengut, E., Gómez-Pinto, I., Lucas, R., Aviñó, A., Eritja, R., González, C., Morales, J.C.
XXXIII Reunión Bienal de la RSEQ. Valencia 25-28 Julio 2011. Poster.
“Quantification of hybridization efficiency with micro-interdigitated electrodes”
Martínez-Rodríguez, S., Prieto, B., Eritja, R., Samitier, J.
Eurosensors XXV, Athens (Greece) 5-7 September 2011.
“Bimolecular parallel G-quadruplex formation from 12-mer human telomeric sequences in
water/organic co-solvent mixtures”
Ferreira, R., Marchand, A., Eritja, R., De Pauw E., Gabelica, V.
Second training school COST G4net, Spa (Belgium) 11-15 September 2011. Poster.
“Synthesis of G-rich and modified oligonucleotides”
Eritja, R.
Second training school COST G4net, Spa (Belgium) 11-15 September 2011. Tutorial lecture.
“DNA derivatives for the fabrication of biosensors”
Manning, B., Garibotti, A., Pérez-Rentero, S., Gállego, I., Eritja, R.
E-MRS Fall meeting. Warsaw (Poland) 19-23 September 2011. Invited speaker.

REFEREE FOR THE FOLLOWING JOURNALS
Journal of American Chemical Society
Journal of Organic Chemistry
Helvetica Chimica Acta
Bioorganic & Medicinal Chemistry
Nucleic Acids Research
Nucleosides, Nucleotides & Nucleic Acids
Current Medicinal Chemistry
Organic and Biomolecular Chemistry
Journal of Chemical Society- Chemical Communications
Bioconjugate Chemistry
Letters in Peptide Science
Langmuir
Organic Letters
The Open Journal of Organic Chemistry
Member of the editorial board:
Journal of Nucleic Acids, SAGE-Hindawi
The Open Organic Chemistry Journal, The Open Medicinal Chemistry Journal and Current
Medicinal Chemistry, Bentham