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Transcortical anesthesia as a first-line treatment for children: - Rident

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Paediatric Odontology<br />

Professional training<br />

E. MOULIS 1 , O. CHABADEL 2 , N. ESCUDERO-PAPOT 2 , M.C. GOLDSMITH 3<br />

<strong>Transcortical</strong> <strong>anesthesia</strong><br />

<strong>as</strong> a <strong>first</strong>-<strong>line</strong> <strong>treatment</strong><br />

<strong>for</strong> <strong>children</strong>:<br />

Minimal doses <strong>for</strong> maximum<br />

effectiveness?<br />

Intraosseous <strong>anesthesia</strong> <strong>for</strong> a child is an effective<br />

technique, able to be used <strong>as</strong> <strong>first</strong>-<strong>line</strong> <strong>treatment</strong> or <strong>as</strong> a<br />

complement <strong>for</strong> a local or local-regional <strong>anesthesia</strong>. As a<br />

<strong>first</strong>-<strong>line</strong> <strong>treatment</strong>, intraosseous <strong>anesthesia</strong> allows an<br />

immediate, painless <strong>anesthesia</strong>, and by limiting the<br />

<strong>anesthesia</strong> of the soft tissues it considerably reduces the<br />

risk of post-operative bites, in particular of the lower lip.<br />

However, the use of this technique and in particular<br />

Quick-Sleeper <strong>for</strong> a child requires carrying out a<br />

preoperative radiographic x-ray, in order to accurately<br />

locate the cortical per<strong>for</strong>ation site, allowing a rigorous<br />

training to optimise the results and to adapt the procedure<br />

to the various clinical situations. Beside these undeniable<br />

clinical advantages <strong>for</strong> a child, the intradiploic injection of<br />

the anesthetic solution also makes it possible to both<br />

decre<strong>as</strong>e the anesthetic quantity of solution injected, and<br />

to limit the toxicity.<br />

Key words<br />

Anesthesia, <strong>children</strong>, intradiploic<br />

The improvement of the conditions of local <strong>anesthesia</strong> <strong>for</strong> a child<br />

is a permanent research <strong>for</strong> the pediatric odontologists, and<br />

correctly translates their conception to work in greatest com<strong>for</strong>t,<br />

without pains and adverse effects. Thus the ideal <strong>anesthesia</strong><br />

would be painless, immediate, without failures, without<br />

after-effects (bites, inflammations or necroses) and per<strong>for</strong>med<br />

completely safely. The m<strong>as</strong>tery of the different techniques, the<br />

knowledge of the anatomy and pharmacology on local<br />

anaesthetics and on v<strong>as</strong>oconstrictors are a prerequisite to the<br />

<strong>anesthesia</strong>’s success. Moreover, the use of<br />

electronically-controlled injection systems and the realisation of<br />

transcortical or intraosseous injections make it possible today to<br />

still improve the conditions of local <strong>anesthesia</strong>, avoiding the<br />

failures in more delicate situations of the mandibular molars<br />

and/or in inflammatory stages. In this local <strong>anesthesia</strong><br />

optimisation view, the use of Quick-Sleeper represents <strong>for</strong> the<br />

child or the teenager an undeniable contribution and constitutes<br />

an additional instrument to improve the effectiveness of our<br />

<strong>anesthesia</strong>, while limiting their toxicity by reducing the quantity of<br />

anesthetic solution injected.<br />

1. University conference lecturer, hospital practitioner, pediatric<br />

odontology, Department of Research and Training in<br />

odontology, Montpellier I, France.<br />

2. Hospital-university <strong>as</strong>sistant, pediatric odontology, Department of<br />

Research and Training in odontology, Montpellier I, France.<br />

3. University Professor, hospital practitioner, pediatric odontology, Department<br />

of Research and Training in odontology, Montpellier I, France.<br />

LE CHIRURGIEN-DENTISTE DE FRANCE I N° 1321 18 OCTOBE R 2007


The pressure allows to the needle to penetrate in the intr<strong>as</strong>eptal<br />

spongy bone. Intraosseous <strong>anesthesia</strong> in temporary teeth is done<br />

in intr<strong>as</strong>eptal, in mesial or in distal of the tooth to be treated, with<br />

or without needle rotation. Preoperative radiography<br />

examination is imperative in order to visualize the structures<br />

present (Fig. 5 and 6).<br />

In young permanent teeth<br />

The periodontium acquires its maturity and sees its incre<strong>as</strong>ing<br />

degree of mineralization, the intradiploic injection then requires<br />

the per<strong>for</strong>ation of cortical by a rotation movement set to the<br />

needle. The choice of injection point meets several criteria, the<br />

<strong>first</strong> relates to the needle position and orientation. The needle<br />

shall be positioned in order to remain perpendicularly to the<br />

osseous cortical exactly in the tooth middle space, following a<br />

vertical <strong>line</strong> p<strong>as</strong>sing by the papilla (Fig. 7): between 3 and 5 mm<br />

above the collar <strong>line</strong> at the jawbone and between 2 and 3 mm<br />

under the collar <strong>line</strong> at the mandible. In order to still improve the<br />

ergonomic conditions, new sites of injection are currently<br />

proposed by the originators of Quick-Sleeper.<br />

Fig. 7: Cortical per<strong>for</strong>ation sites in the upper jaw and mandible. Note the axis<br />

of the needle to the mandible which is rectified into posterior in order to<br />

remain perpendicular to the external oblique <strong>line</strong>.<br />

The per<strong>for</strong>ation of the cortical bone is per<strong>for</strong>med by a<br />

discontinuous rotation setting of the needle by foot control. The<br />

number of rotations necessary to per<strong>for</strong>ate varies according to<br />

the thickness and osseous mineralization; the number of<br />

rotations at the mandible is higher [22]. Once the per<strong>for</strong>ation is<br />

per<strong>for</strong>med, the operator h<strong>as</strong> the perception, of a low resistance of<br />

the spongy bone. The osseous per<strong>for</strong>ation is atraumatic and<br />

painless, the cortical tissue being non-innervated [7]. The<br />

LE CHIRURGIEN-DENTISTE DE FRANCE I N° 1321 18 OCTOBE R 2007<br />

needle penetration must be from 3 to 4 mm maximum. The<br />

per<strong>for</strong>ation being per<strong>for</strong>med by the needle, it is not possible to<br />

drill a dental root, in the c<strong>as</strong>e of a poor evaluation of the injection<br />

point. The recommended needles by the manufacturer are<br />

40/100 th 12 mm and 30/100 th 12 mm needles <strong>for</strong> temporary teeth,<br />

and the specific Transcort-S needles have an <strong>as</strong>ymmetrical bevel<br />

in order to facilitate the osseous per<strong>for</strong>ation. The installation of a<br />

protective sleeve around the sheath of the needle makes it<br />

possible to avoid the labial or gingival wounds related to the<br />

needle rotation setting.<br />

Intradiploic injection<br />

The intradiploic injection is the l<strong>as</strong>t stage, and it is per<strong>for</strong>med<br />

after the per<strong>for</strong>ation of the cortical bone, still by foot control.<br />

The electronically-controlled injection makes it possible to<br />

control the injection speed, and the anesthetic quantity injected.<br />

Particularly in temporary teeth, it is recommended to keep the<br />

speed injection slow in order to avoid any pain. A lighting<br />

indicator and an aural signal make it possible to visualize the<br />

injection of each quarter cartridge.<br />

Finally, a second indicator on the control box gives the<br />

possibility to me<strong>as</strong>ure injection resistance, and if resistance is<br />

too great (blocked needle, cortical not per<strong>for</strong>ated or needle in<br />

contact with a dental root), the injection automatically then stops.<br />

Thus, it is appropriate to determine the cause; purge the needle,<br />

repeat the incomplete per<strong>for</strong>ation, or change the per<strong>for</strong>ation site.<br />

The use of Quick-Sleeper, in order to give effective results,<br />

requires training and a regular practice e<strong>as</strong>ily making possible to<br />

exceed the few difficulties encountered in its initial uses.<br />

Ergonomics:<br />

The position of the handpiece, in particular in the posterior<br />

sectors is delicate sometimes, because of the need to respect the<br />

perpendicular position of the needle relative to the osseous<br />

cortical. However, the new sites of osseous per<strong>for</strong>ation have a<br />

largely improved accessibility [26].<br />

Perception of the per<strong>for</strong>ation:<br />

The perception of a less osseous resistance <strong>as</strong>sociated with the<br />

needle penetration in the spongy bone is sometimes very subtle,<br />

and can go unperceived.<br />

Blocked needle:<br />

During the per<strong>for</strong>ation by the needle rotation, the operator must<br />

imperatively not exert any pressure, with the risk to see the<br />

needle blocked by a cortical stopper and to thereafter prevent the<br />

injection


Table 1: <strong>Transcortical</strong> <strong>anesthesia</strong> results obtained with Quick-Sleeper 2 according to the <strong>treatment</strong> per<strong>for</strong>med.<br />

Teeth Dental care Success Failures Context<br />

Conservative care 8 0<br />

Temporary Pulpotomy 41 3 2 <strong>treatment</strong>s that are too long. 1 fearful child<br />

Avulsion 13 2 2 periodontal impairments (parulis)<br />

Total 61 5<br />

Conservative care 28 3 NAD<br />

Permanent Endodontics 6 1 Extended duration <strong>treatment</strong>, <strong>anesthesia</strong> too short<br />

Avulsion 8 2 2 Insufficient lingual <strong>anesthesia</strong><br />

Total 41 6<br />

Likewise, after several successive rotations, in the c<strong>as</strong>e of thick<br />

cortical bones, the needle can be clogged. In this c<strong>as</strong>e, it is<br />

possible to directly purge the needle in the oral cavity of the<br />

patient by a f<strong>as</strong>t speed injection after having retracted the needle<br />

from the bone.<br />

Duration of <strong>anesthesia</strong>:<br />

The injection of a small quantity of anesthetic (1/2 cartridge) can<br />

limit the duration of the <strong>anesthesia</strong>. But the injection of a greater<br />

quantity or the use of cartridges containing a 1/100,000 th or<br />

1/80,000 th concentration of v<strong>as</strong>oconstrictor according to<br />

pathology, make it possible to compensate <strong>for</strong> this drawback,<br />

and the choice must depend on the supposed duration of the<br />

operational procedure and the local conditions (infection,<br />

inflammation) [15, 22, 23]. The <strong>anesthesia</strong> obtained by<br />

transcortical injection is immediate, only one injection allowing<br />

the pulpal, vestibular and lingual periodontal <strong>anesthesia</strong>. The<br />

major advantage <strong>for</strong> <strong>children</strong> and in particular the very young, is<br />

the absence of labial mucosa analgesia which sometimes<br />

prevents severe bites. Operational consequences are very few;<br />

however it is necessary to note some episodes of transitory<br />

tachycardia without consequences <strong>for</strong> the general patient’s state,<br />

because the <strong>anesthesia</strong> cartridge contains a v<strong>as</strong>oconstrictor [4, 10,<br />

21, 25].<br />

L<strong>as</strong>tly, it is necessary to note possible deferred inflammation at<br />

the per<strong>for</strong>ation site, <strong>as</strong>sociated with light pains, more frequent at<br />

mandible (3.55% at the mandible against 2.83% at the jawbone)<br />

[22]. The rare contra-indications of the transcortical <strong>anesthesia</strong><br />

must be listed: significant alveolus, radicular proximity, or acute<br />

alveolar abscess, infection and inflammation decre<strong>as</strong>ing the<br />

effectiveness of the <strong>anesthesia</strong> [5, 15].<br />

RETROSPECTIVE STUDY CONDUCTED AT THE<br />

MONTPELLIER UNIVERSITY HOSPITAL<br />

Equipment and methods<br />

The objective of this study w<strong>as</strong> to evaluate the average quantity<br />

of anesthetic solution used to per<strong>for</strong>m transcortical <strong>anesthesia</strong> by<br />

Quick-Sleeper, <strong>for</strong> the realization of conventional <strong>treatment</strong>:<br />

LE CHIRURGIEN-DENTISTE DE FRANCE I N° 1321 18 OCTOBE R 2007<br />

Table 2: <strong>Transcortical</strong> <strong>anesthesia</strong> results obtained with Quick-Sleeper 2 according to the <strong>treatment</strong><br />

per<strong>for</strong>med presented in the <strong>for</strong>m of percentages.<br />

Teeth Dental care Success Failures<br />

Temporary Conservative care 100% 0%<br />

Pulpotomy 93,2% 6,8%<br />

Avulsion 86,7% 13,3%<br />

Conservative care 90,3% 9,7%<br />

Permanent Endodontics 85,7% 14,3%<br />

Avulsion 80% 20%<br />

conservative care, pulpotomies, pulpectomies or avulsions.<br />

This study involved 97 <strong>children</strong>, including 54 girls and 43 boys,<br />

ages 4 to 14, treated in the pediatric odontology functional unit<br />

of Montpellier University Hospital, by D3 and Tl students (5th<br />

and 6th years).<br />

113 teeth were concerned, including 66 temporary teeth and 47<br />

permanent teeth. The <strong>anesthesia</strong> w<strong>as</strong> per<strong>for</strong>med by the same<br />

operator having attended one day of training on transcortical<br />

<strong>anesthesia</strong> and on the use of Quick-Sleeper. Children affected<br />

with general pathologies or presenting co-operation difficulties<br />

did not participate in the study. The anesthetic solution used w<strong>as</strong><br />

articaine hydrochloride 4%, with adrena<strong>line</strong> at 1/100,000 th . The<br />

average quantities of injected anesthetic solution were 0.67<br />

cartridge <strong>for</strong> temporary teeth, i.e. about 2/3 of a cartridge, and<br />

0.93 cartridge <strong>for</strong> permanent teeth. The number of rotations<br />

allowing the per<strong>for</strong>ation of cortical in temporary teeth w<strong>as</strong> 0 or 1,<br />

and in permanent teeth it varied between 1 and 4 according to the<br />

thickness of the cortical bone.<br />

Results<br />

The results are presented in tables 1, 2 and 3. The success rate <strong>for</strong><br />

temporary teeth is 92.4%, 87.2% <strong>for</strong> permanent teeth, i.e., a 90.2%<br />

success rate, and no labial bites were observed.


Table 3: Maximum number of 1.8 ml cartridges with v<strong>as</strong>oconstrictor <strong>for</strong> a normal<br />

child [18].<br />

0 to 2 years 1 cartridge<br />

3 to 4 years 2 cartridges<br />

5 to 12 years 3 cartridges<br />

> 12 years 4 cartridges<br />

Two permanent teeth (36, 46) could be extracted in an<br />

inflammatory and/or infectious situation (refractory cellulites<br />

after one week of anti-biotherapy), with the injection of only one<br />

cartridge of anesthetic solution, which confirms the power of<br />

this type of <strong>anesthesia</strong>.<br />

Finally, the failure analysis highlighted various factors:<br />

- On the one hand the difficulty <strong>for</strong> certain <strong>children</strong> to<br />

differentiate feeling and pain, the presence of a symptomatology<br />

(pulpitis or infection, parulis), which would have required a<br />

higher v<strong>as</strong>oconstrictor concentration (1/80,000 th ).<br />

- On the other hand, certain failures are related to insufficient<br />

duration of the <strong>anesthesia</strong> correlated with a relatively long<br />

duration of the <strong>treatment</strong> session, those being per<strong>for</strong>med by<br />

inexperienced student practitioners.<br />

Discussion<br />

To decre<strong>as</strong>e the toxicity of local <strong>anesthesia</strong>s and to limit their<br />

complications remain priorities <strong>for</strong> pediatric odontologists.<br />

However, the toxicity of the anesthetic solutions is not higher <strong>for</strong><br />

a child, because after 2 years, their capacity to eliminate<br />

anesthetic is incre<strong>as</strong>ed. In contr<strong>as</strong>t, the most current harmful<br />

effect remains the bite <strong>as</strong>sociated with the absence of sensitivity<br />

of the soft tissues (lower lip or tongue) [12]. Thus, "small<br />

patient" does not mean "small <strong>anesthesia</strong>", but there is a<br />

maximum number of 1.8 ml per kilo-weight anesthetic<br />

cartridges that is not to be exceeded [16-18]. The toxicity risks<br />

related to anesthetic overdose can be decre<strong>as</strong>ed using<br />

v<strong>as</strong>oconstrictors. Indeed, they make it possible to decre<strong>as</strong>e the<br />

intrav<strong>as</strong>cular p<strong>as</strong>sage of the anesthetic solution and ensure the<br />

incre<strong>as</strong>e in the duration and depth of the <strong>anesthesia</strong> by reducing<br />

its systemic effects [14,17].<br />

Thus, the Francophone Society of Oral Medicine and Oral<br />

Surgery recommends the use of v<strong>as</strong>oconstrictors in <strong>children</strong><br />

after 6 months, outside contra-indications, while respecting the<br />

maximum tolerated amounts (table 1). The real<br />

contra-indications of v<strong>as</strong>oconstrictors: an irradiated bone (40<br />

Gy dose), a pheochromocytoma (adrenal tumour), a cardiac<br />

arrhythmia and an unstable arterial hypertension, are very rare in<br />

<strong>children</strong>.<br />

LE CHIRURGIEN-DENTISTE DE FRANCE I N° 1321 18 OCTOBE R 2007<br />

The contribution of the cartridges (9 µg of v<strong>as</strong>oconstrictor in a<br />

cartridge at 1/200,000 th ) is very weak compared to the<br />

endogenous catecholamine rele<strong>as</strong>e among patients, in the event<br />

of pain, stress or anxiety [14,17]. However, the use of<br />

Quick-Sleeper <strong>as</strong> a <strong>first</strong>-<strong>line</strong> <strong>treatment</strong> enabled us to per<strong>for</strong>m<br />

care by limiting the maximum number of cartridges of<br />

<strong>anesthesia</strong> to 0.67 <strong>for</strong> temporary teeth and 0.93 <strong>for</strong> permanent<br />

teeth.<br />

These primary results should still be able to be improved by a<br />

broadened clinical practice. In terms of effectiveness, they are<br />

comparable with those of the study undertaken on <strong>children</strong> from<br />

4 to 16 years old at Rennes University Hospital showing a<br />

transcortical <strong>anesthesia</strong> success rate higher than 90%, with a<br />

quantity of anesthetic solution injected of 0.45 cartridge on<br />

average (anesthetic solution with adrena<strong>line</strong> at 1/200,000 th ) [20].<br />

These are results also comparable with the results obtained by<br />

transcortical <strong>anesthesia</strong> during previous clinical studies<br />

conducted on adult patients [20].<br />

The results can approach 100% success if we correctly choose<br />

the concentration of v<strong>as</strong>oconstrictor. However, the practice of<br />

the transcortical <strong>anesthesia</strong>s is still restricted, remaining <strong>for</strong><br />

some a complementary technique, used only <strong>as</strong> a second-<strong>line</strong><br />

<strong>treatment</strong> to improve and rein<strong>for</strong>ce an insufficient mandibular<br />

<strong>anesthesia</strong> in the posterior sectors [3, 9, 11, 19].<br />

CONCLUSION<br />

<strong>Transcortical</strong> <strong>anesthesia</strong> can be used <strong>as</strong> a <strong>first</strong>-<strong>line</strong> <strong>treatment</strong> <strong>for</strong><br />

<strong>children</strong> and teenagers, <strong>for</strong> preservation <strong>treatment</strong>, endodontic<br />

<strong>treatment</strong>, and <strong>for</strong> the avulsions, of temporary or permanent<br />

teeth. It can be used <strong>for</strong> <strong>as</strong>ymptomatic teeth but also <strong>for</strong><br />

symptomatic teeth (pulpitis, infections). In the same way,<br />

transcortical <strong>anesthesia</strong> can be used <strong>as</strong> a second-<strong>line</strong> <strong>treatment</strong>,<br />

in situations where the loco-regional (mandibular nerve block)<br />

<strong>anesthesia</strong> is insufficient. The use of this technique <strong>for</strong> a child,<br />

e<strong>as</strong>ily accepted and relatively simple, after a training period, is<br />

incontestably a new tool in the pediatric odontology therapeutic<br />

arsenal. It makes it possible to limit the amounts of injected<br />

anesthetic solution and the complications of local and regional<br />

<strong>anesthesia</strong>, in particular labial self-bites in the youngest <strong>children</strong>.<br />

Forthcoming studies will make it possible to still improve the<br />

effectiveness, the choice and the management of the quantities<br />

of anesthetic solution injected, b<strong>as</strong>ed on the different clinical<br />

situations.


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