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Individual Drugs. ABIES (Tsuga canadensis). - Southwest School of ...

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ÆSCULUS GLABRA.<br />

The bark and fruit <strong>of</strong> Aesculus glabra, Willdenow (Nat. Ord. Sapindaceae). A small<br />

fetid tree common to the central portion <strong>of</strong> the United States.<br />

Common Names: Ohio Buckeye, Smooth Buckeye, Fetid Buc eye.<br />

Principal Constituents.—The glucoside aesculin (C15 H16 O9) (displays a blue<br />

fluorescence in water and more strongly in the presence <strong>of</strong> alkalies); aesculetin<br />

(C9H6O4); a peculiar tannin and saponin. Starch is abundant and a rich yellow oil<br />

is present.<br />

Preparation.—Specific Medicine Aesculus. (Made from the ripe fruit.) Dose, 1 to 15<br />

minims. The smaller doses are to be preferred.<br />

Specific Indications.—Sense <strong>of</strong> constriction, tightness, or uneasiness<br />

in the rectum, with or without hemorrhoids; intestinal irritation with<br />

constriction and colicky pain near the umbilicus; dyspnea and<br />

constriction <strong>of</strong> the respiratory tract with spasmodic cough.<br />

Action.—The dried, powdered fruit <strong>of</strong> the buckeye causes violent<br />

sneezing. Buckeye acts powerfully upon the nervous and circulatory<br />

systems. Its action is probably strongest on the spinal nerves, and in<br />

some respects resembles that <strong>of</strong> strychnine. The cerebrum is also<br />

impressed by it. Toxic symptoms include dizziness, fixation <strong>of</strong> the eye,<br />

impaired vision, vomiting, wry-neck, opisthotonos, stupor, and<br />

tympanites. In lethal doses these symptoms are increased, coma comes<br />

on, and the victim dies. Cattle are <strong>of</strong>ten killed by eating buckeyes; if<br />

not fatal, a condition known as "blind staggers" is produced.<br />

Therapy.—Aesculus is sedative, somewhat narcotic, and has a special<br />

control over the portal circulation, relieving venous congestion. When<br />

the circulation is rapid and the constrictive sensation prominent and<br />

dyspnea prolonged, it relieves such conditions as continuous<br />

asthmatic breathing. There is a sense <strong>of</strong> constriction back <strong>of</strong> the upper<br />

portion <strong>of</strong> the sternum, with or without irritative cough, that is relieved<br />

by it. It is useful in intestinal irritability with the contractive colic-like<br />

pain centering in the umbilical region, probably dependent most<br />

largely upon hepatic or portal congestion and associated with chronic<br />

constipation. Its chief value, however, lies in its power to relieve<br />

Felter’s Materia Medica - (A) - Page 15

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