S. pneumoniae

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TOOLS FOR PATHOGEN DISCOVERY Diagnostics & Surveillance Platforms Inexpensive, high throughput multiplex assays for direct microbial detection Sequencing Improvements in read length, efficiency, cost & fidelity Sample Preparation New strategies for subtracting host sequences prior to analysis Serology/Host Response Multiplex platforms
GROWTH OF THE VIRAL SEQUENCE DATABASE (Pre-1982) PhiX174 is s firt sequenced genome with Sanger dideoxy Epstein-Barr virus HIV Iden fied PCR Dyeterminator Human Genome Capillary electrophoresis TIGR Hantavirus Ebola Zaire Thermostable AB 3700 & MegaBACE Nipha Virus West Nile Virus SARS Avian Solexa 1G 454 Life Sciences Pandemic Influenza AB SOLiD Lipkin, MMBR 2010
Page 1: Metagenomics for Identifying Viral
Page 6 and 7: BUSHMEAT TRADE Potential risk for i
Page 8 and 9: INTERNATIONAL TRAVEL Countries with
Page 10 and 11: ROLE OF CLASSICAL MICROBIOLOGY IN P
Page 12 and 13: Causation: Implication of microbes
Page 15 and 16: Influenza-like Illness Sentinel Phy
Page 17 and 18: Epidemiology of H1N1pdm First case:
Page 19 and 20: S. pneumoniae is highly associated
Page 21 and 22: DIFFERENTIAL DIAGNOSIS OF VIRAL HEM
Page 23 and 24: NonParametric results: Binomial tes
Page 25 and 26: PYROSEQUENCING Thomas Briese Sean C
Page 27 and 28: DIFFERENTIAL DIAGNOSIS OF UNEXPLAIN
Page 30 and 31: Date: Fri, 10 Oct 2008 17:00:32 -04
Page 32 and 33: Lujo virus, a new hemorrhagic fever
Page 34 and 35: G1 MOBV, MOPV, IPPYV, LASV, LUJV L
Page 36 and 37: Viruses discovered/characterized at
Page 38 and 39: FO RGOTTEN SCRIPTS Raul Rabadan 53
Page 41 and 42: Immunosignatures of infectious dise
Page 43: www.cii.columbia.edu

S. pneumoniae

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