S. pneumoniae
S. pneumoniae
S. pneumoniae
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Immunosignatures of infectious diseases<br />
Center for Infection and Immunity<br />
Columbia University<br />
Bioinformatics, serology<br />
Center for Innovations in Medicine<br />
Arizona State University<br />
Photolithography, chemical engineering<br />
Establish a serological platform for detecting antibody responses to representative B-cell epitopes for 1,000 pathogens using:<br />
A) Empirically-established epitopes from the Immune Epitope Database & Analysis Resource (http://www.immuneepitope.org)<br />
B) Predicted epitopes from proteins on native arrays that are reactive with human sera<br />
C) Peptides designed using algorithms for B-cell epitope prediction
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