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Saving Mothers' Lives: - Public Health Agency for Northern Ireland

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Table 20.1<br />

Inclusion criteria used in 2003-05<br />

Code Category Defi nition<br />

1<br />

Major obstetric<br />

haemorrhage<br />

2 Eclampsia<br />

3<br />

Renal or Liver<br />

dysfunction<br />

4 Cardiac arrest No detectable major pulse.<br />

5 Pulmonary oedema<br />

6<br />

Acute respiratory<br />

dysfunction<br />

Estimated blood loss ≥2,500ml, or transfused fi ve or more units of blood, or<br />

received treatment <strong>for</strong> coagulopathy (fresh frozen plasma, cryoprecipitate,<br />

platelets). (Includes ectopic pregnancy meeting these criteria.)<br />

Seizure associated with antepartum, intrapartum or postpartum symptoms and<br />

signs of pre-eclampsia.<br />

Acute onset of biochemical disturbance, urea > 15mmol/l, creatinine >400mmol/l,<br />

aspartate aminotransferase / alanine aminotransferase >200u/l.<br />

Clinically diagnosed pulmonary oedema associated with acute breathlessness<br />

and 0 2 saturation < 95%, requiring 0 2 , diuretics or ventilation.<br />

Requiring intubation or ventilation <strong>for</strong> >60 minutes (not including duration of<br />

general anaesthetic).<br />

7 Coma Including diabetic coma. Unconscious >12 hours<br />

8<br />

Cerebro-vascular<br />

event<br />

Stroke, cerebral/cerebellar haemorrhage or infarction, subarachnoid<br />

haemorrhage, dural venous sinus thrombosis.<br />

9 Status epilepticus Unremitting seizures in a patient with known epilepsy.<br />

10 Anaphylactic shock<br />

11 Septicaemic shock<br />

An allergic reaction resulting in collapse with severe hypotension, diffi culty<br />

breathing and swelling/rash.<br />

Shock (systolic blood pressure 20 per minute), tachycardia, hypotension.<br />

Diagnosed as ‘high’ probability on V/Q scan or positive spiral chest CT scan.<br />

Treated by heparin, thrombolysis or embolectomy.<br />

Unit equipped to ventilate adults. Admission <strong>for</strong> one of the above problems or <strong>for</strong><br />

any other reason. Include admissions to Coronary Care Units.<br />

During the 2003 to 2005 triennium, 845 women were reported as meeting one or more of our defi ned<br />

inclusion criteria. Using a denominator of 159,223 maternities, the rate of severe maternal morbidity during<br />

the triennium was 5.3 with a 95% confi dence interval from 5.0 to 5.7 per 1000 maternities). During the<br />

triennium, 15 Direct or Indirect maternal deaths were reported to the Confi dential Enquiry into Maternal<br />

Deaths in Scotland; giving a ‘near-miss to death ratio’ of 56:1, with a 95% CI from 34:1 to 100:1.<br />

Many women met the defi nitions <strong>for</strong> more than one severe morbidity category. For example, some suffered<br />

major haemorrhage and were admitted to intensive care. Thus, during the triennium the 845 women who<br />

were reported to us experienced a total of 1,135 events meeting our inclusion criteria. Rates of the 14<br />

individual categories of severe morbidity are summarised in Table 20.2. Major obstetric haemorrhage<br />

was the most numerous category occurring in 582 women during the triennium. Thus major haemorrhage<br />

occurred in 69% of all 845 women with severe maternal morbidity.<br />

249

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