Name: Gilbert Weidinger Date of birth: December 8 ... - Universität Ulm

CURRICULUM VITAE
Name: Gilbert Weidinger
Date of birth: December 8, 1970 in Salzburg, Austria
Nationality: Austria
Address: Ulm University
Institute for Biochemistry and Molecular Biology
Albert‐Einstein‐Allee 11
89081 Ulm
Tel. 0049 731 500 23290
Fax. 0049 731 500 23290
email. gilbert.weidinger@uni‐ulm.de
web. www.uni‐ulm.de/weidinger
PROFESSIONAL EXPERIENCE
2012 ‐ present University of Ulm, Medical Faculty, Germany
Associate Professor (W3 oL) at the Institute for Biochemistry and
Molecular Biology
Main focus: Cellular and molecular mechanisms of organ regeneration in the zebrafish.
2006 – 2011 Technische Universität Dresden, Germany
Group Leader at the Biotechnology Center (BIOTEC) and the Center for
Regenerative Therapies
Main focus: Molecular regulation of organ regeneration in the zebrafish.
2002 – 2006 University of Washington School of Medicine, Seattle, USA
Postdoctoral Fellow in the lab of Randall Moon, Howard Hughes Medical
Institute at the Department of Pharmacology
Subject: The role of Wnt signaling and Wnt target genes in zebrafish development and
organ regeneration.
2001 Max‐Planck‐Institute for Biophysical Chemistry, Göttingen, Germany
continuation of PhD thesis in the lab of Erez Raz
1998 – 2000 University of Freiburg, Germany
PhD thesis in the lab of Erez Raz at the Department of Developmental Biology
Subject: Specification and migration of germ cells in zebrafish.

EDUCATION
2001 Doctoral Degree in Biology/Genetics 27.9.2001 (Dr. rer. nat) Very good with
distinction,
University of Salzburg, Austria
2001 Max‐Planck‐Institute for Biophysical Chemistry, Göttingen, Germany
(Erez Raz): PhD studies
1998‐2000 University of Freiburg, Germany (Erez Raz): PhD studies
1997 University of Salzburg, Austria: Diploma Biology/Genetics (Mag. rer. nat.)
Very good with distinction
1989‐1997 University of Salzburg, Austria: Diploma Studies of Biology/Genetics
1989 Matura (Austrian high school diploma). Very good with distinction.
Erzbischöfliches Privatgymnasium Borromäum, Salzburg, Austria.
PUBLICATIONS
2013
Bartholomäus Grotek, Daniel Wehner, and Gilbert Weidinger (2013). Notch signaling coordinates cellu‐
lar proliferation with differentiation during zebrafish fin regeneration. Development 140, 1412‐1423.
Sebastian Thieme, Tobias Gyárfás, Cornelia Richter, Günes Özhan, Jun Fu, Dimitra Alexopoulou, Mi‐
chael H. Muders, Irene Michalk, Christiane Jakob, Andreas Dahl, Barbara Klink, Joanna Bandoła, Mi‐
chael Bachmann, Evelin Schröck, Frank Buchholz, A. Francis Stewart, Gilbert Weidinger, Konstantinos
Anastassiadis, and Sebastian Brenner (2013). The histone demethylase UTX regulates stem cell migra‐
tion and hematopoiesis. Blood DOI 10.1182/blood‐2012‐08‐452003.
2012
Enrico Moro, Gunes Ozhan‐Kizil, Alessandro Mongera, Dimitris Beis, Claudia Wierzbicki, Rodrigo M.
Young, Despina Bournele, Domenichini Alice, Leonardo E. Valdivia, Lawrence Lum, Chuo Chen , James
F. Amatruda, Natascia Tiso, Gilbert Weidinger and Francesco Argenton (2012). In vivo Wnt signaling
tracing through a transgenic biosensor fish reveals novel activity domains. Dev Biol. 15, 327‐40.
Donghun Shin, Gilbert Weidinger, Randall T. Moon, Didier Y.R. Stainier (2012). Intrinsic and extrinsic
modifiers of the regulative capacity of the developing liver. Mech. Dev. 128, 525‐35.
2011
Birgit Kagermeier‐Schenk, Daniel Wehner, Günes Özhan‐Kizil, Hideki Yamamoto, Jian Li, Katharina
Kirchner, Christian Hoffmann, Peter Stern, Akira Kikuchi, Alexandra Schambony and Gilbert Weiding‐
er (2011). Waif1/5T4 inhibits Wnt/catenin signaling and activates noncanonical Wnt pathways by
modifying Wnt receptor complex formation and internalization. Dev. Cell 21, 1129‐1143.

Ana Sofia Azevedo, Bartholomäus Grotek, António Jacinto, Gilbert Weidinger* and Leonor Saúde*
(2011). The regenerative capacity of the zebrafish caudal fin is not affected by repeated amputations.
PLOS One 6: e22820.
* corresponding authors
Manon C. Verhoeven, Christa Haase, Vincent M. Christoffels, Gilbert Weidinger and Jeroen Bakkers
(2011) Wnt signaling regulates atrioventricular canal formation upstream of BMP and Tbx2. Birth
Defects Res. (Part A) 91, 435‐40.
Franziska Knopf, Christina Hammond, Avinash Chekuru, Thomas Kurth, Stefan Hans, Christopher W.
Weber, Gina Mahatma, Shannon Fisher, Michael Brand, Stefan Schulte‐Merker and Gilbert Weidinger
(2011). Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin. Dev. Cell 20, 713‐724.
Kristin Schnabel, Chi‐Chung Wu, and Gilbert Weidinger (2011). Regeneration of cryoinjury induced
necrotic heart lesions in zebrafish is associated with epicardial activation and cardiomyocyte prolifera‐
tion. PLOS One 6, e18503.
2010
Franziska Knopf, Kristin Schnabel, Christa Haase, Katja Pfeifer, Konstantinos Anastassiadis, and
Gilbert Weidinger (2010). Dually‐inducible TetON systems for tissue‐specific conditional gene expres‐
sion in zebrafish. Proc. Natl. Acad. Sci. U.S.A. 107, 19933‐19938.
Petros Nemtsas, Erich Wettwer, Torsten Christ, Gilbert Weidinger* and Ursula Ravens* (2010). Adult
zebrafish heart as a model for human heart? An electrophysiological study. J. Mol. Cell. Cardiol. 48,
161‐171.
* corresponding authors and equal contribution
2009
Yoonsung Lee, Danyal Hami, Sarah De Val, Birgit Kagermeier‐Schenk, Airon A. Wills, Brian L. Black,
Gilbert Weidinger and Kenneth D. Poss (2009). Maintenance of blastemal proliferation by functionally
diverse epidermis in regenerating zebrafish fins. Dev. Biol. 331, 270‐80.
Wolfram Goessling, Trista E. North, Sabine Loewer, Allegra M. Lord, Sang Lee, Cristi L. Stoick‐Cooper,
Gilbert Weidinger, Mark Puder, George Q. Daley, Randall T. Moon and Leonard I. Zon (2009). Genetic
Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regen‐
eration. Cell 136, 1136‐47.
Jon P. Lyons, Rachel K. Miller, Xiaolan Zhou, Gilbert Weidinger, Tom Deroo, Tinneke Denayer, Jae‐Il
Park, Hong Ji, Ji Yeon Hong, Annette Li, Randall T. Moon, Elizabeth A. Jones, Kris Vleminckx, Peter D.
Vize, Pierre D. McCrea (2009). Requirement of Wnt/beta‐catenin signaling in pronephric kidney devel‐
opment. Mech. Dev. 126, 142‐59.

Krasimir Slanchev, Juerg Stebler, Mehdi Goudarzi, Vlad Cojocaru, Gilbert Weidinger, Erez Raz (2009).
Control of Dead end localization and activity ‐ Implications for the function of the protein in antagoniz‐
ing miRNA function. Mech. Dev. 126, 270‐7.
2008
Wolfram Goessling, Trista E. North, Allegra M. Lord, Craig Ceol, Sang Lee, Gilbert Weidinger, Caitlin
Bourque, Robbert Strijbosch, Anna‐Pavlina Haramis, Mark Puder, Hans Clevers, Randall T. Moon and
Leonard I. Zon (2008). APC mutant zebrafish uncover a changing temporal requirement for Wnt signal‐
ing in liver development. Dev. Biol. 320, 161‐74.
Karen A. McFarland, Jolanta M. Topczewska, Gilbert Weidinger, Richard I. Dorsky and Bruce Appel
(2008). Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum. Dev.
Biol. 318, 162‐171.
Elly M. Tanaka and Gilbert Weidinger (2008). Micromanaging regeneration. Genes Dev. 22, 700‐705.
Elly M. Tanaka and Gilbert Weidinger (2008). Heads or Tails—Can Wnt tell which one is up? Nat. Cell
Biol. 10, 122‐124.
Jennifer Bonner, Suzanna L. Gribble, Eric S Veien, Oliver B. Nikolaus, Gilbert Weidinger and Richard I
Dorsky (2008). Proliferation and patterning are mediated independently in the dorsal spinal cord down‐
stream of canonical Wnt signaling. Dev. Biol. 313, 398‐407.
earlier
“Gilbert Weidinger: Regeneration researcher”. Interviewed by Ruth Williams (2007). J. Cell Biol. 179,
1088‐1089.
Yukio Nakamura, Gilbert Weidinger, Jennifer O. Liang, Allisan Aquilina‐Beck, Keiko Tamai, Randall T.
Moon, and Matthew L. Warman (2007). Modulation of Wnt and BMP signaling by the CCN family
member Wisp3. J. Clin. Invest. 117, 3075‐86.
Cristi L. Stoick‐Cooper, Randall T. Moon, and Gilbert Weidinger (2007). Advances in signaling in verte‐
brate regeneration as a prelude to regenerative medicine. Genes Dev. 21, 1292‐1315.
Shuichi Ueno*, Gilbert Weidinger*, Tomoaki Osugi*, Aimee D. Kohn, Jonathan L. Golob, Lil Pabon,
Hans Reinecke, Randall T. Moon and Charles E. Murry (2007). Biphasic Role for Wnt/β‐catenin signaling
in cardiac specification in zebrafish and embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 104, 9685‐
9690.
* equal contribution
Cristi L. Stoick‐Cooper*, Gilbert Weidinger*, Kim Riehle, Michael B. Major, Nelson Fausto, and Randall
T. Moon (2007). Distinct Wnt signaling pathways have opposing roles in organ regeneration. Develop‐
ment 134, 479‐489.
* equal contribution

Gilbert Weidinger, Chris Thorpe, Katrin Wuennenberg‐Stapleton, John Ngai, and Randall T. Moon
(2005). The Sp1‐related transcription factor sp5l acts downstream of Wnt/‐catenin signaling in meso‐
derm and neuroectoderm patterning. Curr. Biol. 15, 489‐500.
Chris Thorpe, Gilbert Weidinger, and Randall T. Moon (2005). Wnt/‐catenin regulation of the Sp1‐
related transcription factor sp5l promotes tail development in zebrafish. Development 132, 1763‐1772
Gilbert Weidinger, and Randall T. Moon (2003). When Wnts antagonize Wnts. J. Cell Biol. 162, 753‐5.
Gilbert Weidinger, Jürg Stebler, Krasimir Slanchev, Karin Dumstrei, Clare Wise, Robin Lovell‐Badge,
Christine Thisse, Bernard Thisse, and Erez Raz (2003): dead end, a novel vertebrate germ plasm compo‐
nent, is required for zebrafish primordial germ cell migration and survival. Curr. Biol. 13, 1429‐1434
Brian Ciruna, Gilbert Weidinger, Holger Knaut, Bernard Thisse, Christine Thisse, Erez Raz, and Alex‐
ander F. Schier (2002): Production of maternal‐zygotic mutant zebrafish by germ‐line replacement. Proc.
Natl. Acad. Sci. U.S.A. 99, 14919‐14924
Gilbert Weidinger, Uta Wolke, Christine Thisse, Bernard Thisse & Erez Raz (2002): Regulation of
zebrafish primordial germ cell migration by attraction towards an intermediate target. Development
129, 25‐36.
Uta Wolke, Gilbert Weidinger, Marion Köprunner & Eraz Raz (2002): Multiple levels of post‐
transcriptional control lead to germ line specific gene expression in the zebrafish. Curr. Biol. 12, 289‐294.
Gilbert Weidinger*, Uta Wolke*, Marion Köprunner, Michael Klinger & Erez Raz (1999): Identification
of tissues and patterning events required for distinct steps in early migration of zebrafish primordial
germ cells. Development 126, 5295‐5307.
* equal contribution
Fritz Aberger, Gilbert Weidinger, Horst Grunz & Klaus Richter (1998). Anterior specification of embry‐
onic ectoderm: the role of the Xenopus cement gland‐specific gene XAG‐2. Mech. Dev. 72, 115‐130.
Fritz Aberger, Gilbert Weidinger & Klaus Richter (1997): A member of the Met/HGF‐receptor family is
expressed in a BMP‐4‐like pattern in the ectoderm of Xenopus gastrulae. Biochem. Biophys. Res. Comm.
231, 191‐195.
FELLOWSHIPS & PRIZES
2012 Oskar‐Lapp‐Fellowship of the German Cardiac Society.
2002 – 2005 APART postdoctoral fellowship of the Austrian Academy of Sciences
1998 – 2001 Marie Curie Fellow in the program „Training and Mobility of Researchers“of
the European Community