Belém VIRUS Laboratory

Appendi:x III
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Tab1e 12 summarizes the data from the BVL on the 7 types.
Only Guama
and Catu have been isolated from man, and serological data for man is only
avai1able for BeAn 8582 (Capim), where 1/37 people was HI positive at Borba,
on the Rio Madeira, and 327 from other parte of the Brazilian Amazon were
negative13 It appears that a11 the viruses except BeAn 20076 (Bushbush-1)
and BeAn 7722 (Mirim), for which the data are insufficient, are more closely
involved with rodents than with marsupials, and with Culex rather than with
other species of rnosquitoes.
Iso1ations of Guama and BeAr 12590 (Moju)
viruses from pools of male Phlebotomus spp. and of Guama from nestling birds
(Troglodytes) are of doubtful validity13 The high antibody rates in
marsupiaIs for these same 2 types are in the arboreal genera CaIIuromys
and Marmosa.
One strain of BeAr 12590 (Moju) was iso1ated froro an unidenti-
fied farest rat9, ather strains af the same virus fram the viscera af a
Proechimys rat and Mansonia spp. trapped in Amapa Territory, and a strain
of Catu virus froro the salivary glands of a bat (~~~ obscurus) algo
froro AmapalO, alI the other Amazonian strains af these viruses being fraro
Para State.
HI antibodies for BeAn 8582 (Capim) in rodents have been shown
to disappear rapid1y, so that the rate of 13% for Proechimys represents on1y
recent infections; Oryzomys have a much lower antibody rate than Proechimys
for this virus and for BeAn 10615 (Guajara), and no N antibodies were de-
9 13 61
tected to the latter in 88 marsupiaIs tested' , .Oryzomys is more
common1y found with viraemia to BeAr 12590 (Moju) than is Proechimys9,13
Transmission to laboratory mice by the bite of naturally infected
mosquitoes caught in the Amazon forest has been successful with 4 of the
virus types, as follows: