Belém VIRUS Laboratory

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$Page 1 .:., ... Revo Insto Medo trapo .\'ão Paulo 36 (2); 171-174 ...$

50 - females and their contacts o The increase at the end of December was apparently due to the pneumonia episode. Moreover, heavy rains which started at the end of December seem to have produced a more intense water pollution in the city's network of distribution. It must be kept in mind that Bioterio NQ 5 which provides breeding stock to the others suffered a delay in filtration until the end of the year. 2 presents the number of babies per litter, an important consideration in the output; it depends on several factors which , uníortunate1y, escape our control in the present conditions. One af them may be heredi tary o Selection is ve~ difficult to achieve because the use of litters for inoculation entails indiscriminate Also lack of space and shortage of mouse boxes do not allow for individual caging af pregnant females, which wauld have the added advantage aí preventing, to a certain degree, cannibalism. Another difficulty resides in the deterioration of the food supply by prolonged storage under adverse conditions temperature and humidityo An attempt to compensate for this deficiency was made by increasing the ration oí whole rice. Figo 2 sha1vs that, in spi te aí a general improvement in the conditions or Bioterio 3, no substantial change has been obtained in the fertilityas represented by litter size Encouraging resulta appear in the rate of litters per mated females, as seen in This may be the consequence of a certain degree of selection obtained by the wi thdrawal of the females from the ma tinE boxes after ten days o There is a definite trend toward the 60% bracket starting at the beginning of November. Two devia tions, one a t the end of October and one in mid-December remain unexplained, total number ar babies is alsa a cause ar aptimism (Fig.4). There was a rioe, as expected, each time that the number of mating boxes was augmented, on Oct. 4 and 23, but the numbers seem to exceed, slightly, the expectationso Here also, the trend is toward a stabilization around the 400 value (5 days mean). This result was obtained in spite of the reduction to 8 of the number of females per cage. It is hoped that the restoration to 10, now deemed possib1e, may produce a significant . improvemcnt. This can be attempted, however, an1y \-Jhen ful1 assurance af contro11ed
Remary.s .. - 51 supply and other infection sources is obtained. 1. The measures applied in Bioterio 3 were later introduced into Bioterio 1, wi th comparable resul ts . The return to the original nurnber of females per ma ting box will be experimented wi th in Bioterio 3 and, according to the resul ts, Bioterio 1 will follow, or keep the present status. 2. As this Report is assembled, the trends appearing at the end of tbe year are being confirmed, and tr.e.graphs of litter rates and number of babies increased production. babies per li tter, and a small reduction in mortali ty. There is even a slight upward trend in the number oí HISTOPATHOlOGY The following animals were exaJTlined durir.(1' the year: Iaboratory 38 adu1 t mice 36 infant mice 17 guineapigs 4 monkeys ~~_tE-C?!ogy of wild animals Wild Other 67 bata 31 prima tes 19 rodenta 10 turt1es 7 edentatcs 6 marsupia1s 3 others 13 ungu1ates 5 carnivores 2 others The liver, kidney, heart, lung, and in some cases oth.er viscera, were exaJnined from 8 rodents i;rom Amapá which had yielded Amaparl virus o Four had hepatic lesions, but these were of a focal, probably parasitic typeo Three had focal lesions of the IrtY"ocardium, 1-1ith inflaITU11ation and degeneration. EIeven rodents trapped in the I~~I~ & Utinga forcsts, alI negative for virus, examined o - One had hepa tic cirrhosis, chronic pneumoni tis and ~ocardi tis.o
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Belém VIRUS Laboratory Belém, Par
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This report is reproduced as receiv
Page 5 and 6: 49 ENTOMOLOGY HumaJl bait catches .
Page 7 and 8: vector, DITRODUCTION With the depar
Page 9 and 10: -3 - Several strains oí íoot-and-
Page 11 and 12: R!oech~ antibody. nheus, 'UF 5 Ilhe
Page 13 and 14: y I. enezuelensis er ever, was 7 A
Page 15 and 16: wever, o follows: 114 "9- B. ~ghnet
Page 17 and 18: EAN cessory -48 th25th RI posi tive
Page 19 and 20: cerine. aboration, th), 13 FIELD ST
Page 21 and 22: suquar~. quitoes. oa from blood of
Page 23 and 24: these (2:160 219 of ~~: others. 4 p
Page 25 and 26: g r, TISSUE CULTURE STUDIBS ON .A.R
Page 27 and 28: lln The following Y1rusea only prod
Page 29 and 30: c lruses peclt'lc. ver, ver. gcs bo
Page 31 and 32: \dse, 25 dilution gave 19-59 plaque
Page 33 and 34: ined: al 27 ENTOM:>lOGY This year t
Page 35 and 36: to 29 - Tables 24 and 25 give the r
Page 37 and 38: -31 (Table 26), so it seems that a
Page 39 and 40: it oes -blower trap catc?es, -33 It
Page 41 and 42: er: on chicken bait, and ~~ B 9 and
Page 43 and 44: ork. ar, -37 from an early biteo Th
Page 45 and 46: h. , .39 suction trap took more mal
Page 47 and 48: 0 ination, RO 5209 (several bleedin
Page 49 and 50: -43 When the test was repeated by p
Page 51 and 52: iolof:;f 45 CATTIE DISEASE In Ju1y
Page 53 and 54: l e, 47 The histopathology in these
Page 55: io. d 49 litter (another possible
Page 59 and 60: is: sis: from these cattle died 1'd
Page 61 and 62: Animal --- attendants and cage wash
Page 63 and 64: 57 Name Institution Date JóC.King
Page 65 and 66: Table 1 (continued) Group or comple
Page 67 and 68: Table 2 (continued) Year 54 55 56 5
Page 69 and 70: - 63 - Table 4 Viruses from Sentine
Page 71 and 72: - 65 - Table 4 - cont. Date Virus S
Page 73 and 74: - 67 - Table 4a Viruses from Sentin
Page 75 and 76: - 69 - Table 5 - cont. Date Virus S
Page 77 and 78: - 71 - Table 6 - cont. Date Pool N
Page 79 and 80: Mosquito - 73 - Table 8 Species of
Page 81 and 82: - 75 - Table 10 Vertebrate specimen
Page 83 and 84: - 77 - Table 11 Changes in HI antib
Page 85 and 86: Table 13 Ectoparasites inoculated f
Page 87 and 88: . ..:t\i\'O . J:3 1I .I . I. ~t:8Â
Page 89 and 90: Tabl. 14 ~rtc Platon Sagu1nU8 Proe~
Page 91 and 92: Table 19 Results of CF tests using
Page 93 and 94: Table 27 Ground level mosquito capt
Page 99 and 100: Table 24 Daytime catches on human b
Page 101 and 102: -95- Table 5 Daytime catches on hum
Page 103 and 104: Table 27 Mosquitoes and Phlebotomus
Page 105 and 106: Table 28 Mosquitoes & Phlebotomus t
Page 107 and 108:
Table 29 Mosquitoes by kind and mon
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o C"'\ C1> ri ~ E-i * I-i ~ ~ ~ ~ ~
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Table 30 (continued) 31 28 31 30 31
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Table 31 (continued) Total Feb Mar
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~ C"'\ C"'\ r-I 'fJ E-t G) S ! .s
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- ~~§() '-" -:t (""\ Q) .-I .o ~ -
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.. 'S .~ ~ ~o() '-" \J\ I"'") Q) .-
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115 - Table 37 *1e l11lebotOllUB ca
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, Jan.22 26 28 7 7 20 22 23 23 Jul,
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:r :r" :B, -119- Table lu V1Z'a8..
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-121 V1IuIea 18 ola ted. trCII1 -te
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124 ~ () .- '-- ~I() .~ w (X)~ ~ -~
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Fig. 5. 126 The new meteorological
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Fig. cages, intervals. 128 - 7. The
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APPENDIX I TRE SEROLOGICAL RESPONSE
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al. I -133 - These results offer a
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5 Appendix I Bleeding Date Table 2
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[ Appendix I U) w U) :) ~ .5 fi O-
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Appendix I IC') ~ o: ::> (.!) ~ tI>
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Appendix II p60ple, bIlt tilere 18
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Appendi:x: II -144 where, 1n 1932,
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o. v.2-'1 Appendix II Op}X)r'bm1tie
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-148-
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Appendix II -150 - otJ1er cases bac
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Appendix II \m1.torm1:3' L negat.1v
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Appendi:z: 11 -154- case *ria Ria (
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Appendix II -156 - v1rQlence on tll
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Beni, Brazil. Highways, Appendix II
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Appendix III Influenza -160 - MYXOV
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odents, Lingual 1956, Appendix III
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us31, hibition, ver, ucambo. n, App
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oasta1 aboratory p1dem1cs, . mazoni
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Appendix III -168 - (Bradypus) from
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fter t. Appendix III -170 - mosquit
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itoes, rker, es. Appendix rn -172 T
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Appendi:x III -174 - Tab1e 12 summa
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Appendix liI Kairi vírus has been
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Appendix ll! 178 13/53 peop1e at La
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Appendix III -180 - Ungrouped Arbov
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~ppendix li! and the vírus can pro
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Appendix III -184 Several mosquito
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1. 3. figs. Hyg. ~:372-96, li:620-6
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Appendix III -188 CAUSEY O. R., CAU
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31. ~3. 15. ~4 . ~ppendix -190 5ROP
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50. Panamer. Para, Trap. mosquitoes
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Appendix III CAUSEY O. R., SHOPE R.
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Appendix III -196 - JOHNSON K. M.,
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Appendix III
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Appendix III 200 - Table 3 Arboviru
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LI"\ QJ ~ .c tU E-4 Appendi:x ~ ti)
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Appendi:x: III V i r u s Aedes spp.
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0\ 41 .-I ~ ~ JJ ~ Appendix III a r
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Tab1e Isolates Sentinel 141 14 13%c
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