BD Biopharmaceutical Production

INTRODUCTION
It is our commitment to innovation and product consistency as well as our broad access
to the raw material market that makes BD (Becton, Dickinson and Company) such a
strong global supplier and partner. In over 142 countries worldwide, BD offers a full line
of bionutrients and media, for the biotechnology, pharmaceutical, animal and human vaccine,
and bioremediation markets. BD offers products for both cell culture and microbial
fermentation production, as well as applications for industrial research, QA/QC and
environmental monitoring.
Capability
The BD Difco and BBL Bionutrient Technical Manual has
been provided to assist you in your selection of BD products
for use in cell culture and microbial fermentation production,
from Research and Development to the final finished product.
Our commitment to the cell culture and fermentation media market is exemplified in our
wide range of capabilities:
• Largest media manufacturing plant in the world—In 1999, as part of the Difco
Laboratories acquisition, BD opened a manufacturing plant in Sparks, Maryland, which
is our Center of Manufacturing Excellence. With over 101,000 sq. ft. of production
capacity, the center is a state-of-the-art modern facility that manufactures dehydrated
culture media, prepared culture media, bionutrient ingredients, stains, and other
products for microbiological and cell culture use worldwide.
• Full line of meat peptones—Building on the reputation of the Difco meat peptones,
BD continues to operate the previous Difco manufacturing facility in Detroit as a source
for the high quality Difco and Bacto brand products. This commitment to tradition
carries on the quality and performance established under the Difco name, long
recognized throughout the industry for superior quality. BD continues investing in
Research and Development for peptone products, which continually expands our
understanding of their application in cell culture and microbial fermentation.
• Expanding line of animal-free products—As early as 1998, BD started offering
animal-free products to the fermentation industry, introducing its Select APS
(Alternative Protein Source) Super Broth, Select APS LB Broth, and Select Soytone.
BD continues to leverage its expertise in creating high performing animal-free products
to meet evolving customer needs in the cell culture and fermentation industry with
the introduction of Difco Springer DS 100 Soy Peptone UF.
BIONUTRIENT TECHNICAL MANUAL • SECOND EDITION
Today, BD Offers the
following Animal-Free
Products
• Phytone Peptone
• Phytone Peptone UF
• DS 100 Soy Peptone UF
• Select Soytone
• Bacto TC Yeastolate
• TC Yeastolate UF
• Bacto Yeast Extract
• Yeast Extract
• Yeast Extract UF
• Yeast Extract LD
• Select APS LB Broth
• Select APS Super Broth
• Bacto Malt Extract
• M9 Minimal Salts, 5x
• Yeast Nitrogen Base
• Yeast Nitrogen Base
w/o Amino Acids
• Yeast Nitrogen Base
w/o Amino Acids and
Ammonium Sulfate
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