pathology services handbook - St George's Healthcare NHS Trust

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5.8 HAEMOSTASIS REFERENCE RANGES SCREENING TEST REFERENCE RANGE INR 0.8 – 1.1 Activated Partial Thromboplastin time ratio APTTR 0.85 – 1.15 Thrombin time 11 – 16 secs Reptilase time Control + 4 secs Fibrinogen 2 – 4 g/L D-dimers - immunological 2.2 – 3.5 Factor V Leiden PCR If APCR < 2.2 Prothrombin mutation PCR If there is clinical suspicion of thrombophilia Factor VIII 50-150u/dl Pathology Services Handbook v3.2.2 - February 2013 49 of 81
5.9 BLOOD TRANSFUSION For blood grouping, antibody screening and crossmatching, please provide 6 mL in special Pink cap EDTA tube. If you wish to convert a “Group and Save” to a crossmatch, please telephone the laboratory on 5471. Plasma saved for 1 week. Allow 1 clear working day for elective crossmatching. Crossmatched blood is routinely returned to stock after 24hrs unless discussed with the laboratory. 5.10 BLOOD PRODUCTS AVAILABLE Fresh Frozen Plasma Order by telephone, giving clinical disorder requiring the product. Cryoprecipitate Order by telephone, giving clinical disorder requiring the product. Platelet concentrate Platelets – usually available within 2 hours. Order by telephone: May require Clinical Human Albumin Solution (HAS) (4.5% and 20%) 5.11.1 ANTI-D IMMUNOGLOBULIN Haematology confirmation. Blood group not required. Routine Antenatal prophylaxis is offered to all RhD Negative patients. 1500 iu Anti-D is given at 28 weeks. For Rh D negative woman (or mother), post-delivery of RhD positive child 500 iu. Kleihauer performed automatically. Ward informed if further Anti-D required and the need for a further Kleihauer examination, or referral of sample to National Blood Service for confirmatory testing. Following spontaneous/therapeutic abortion, give 500 iu. Anti-D should be administered within 72 hours A Kleihauer test should be requested where gestation is 20 weeks or more. Addressograph labels, unclear or incorrectly labelled samples will NOT be accepted. Both the request form and blood sample must be labelled with the following: First name, surname, hospital number, date of birth and gender, and samples must be signed and dated. It is Hospital policy to reject incorrectly labelled Transfusion samples. No changes are allowed to rejected samples. Pathology Services Handbook v3.2.2 - February 2013 50 of 81
Page 1 and 2: PATHOLOGY SERVICES HANDBOOK http://
Page 3 and 4: PREFACE This handbook outlines the
Page 5 and 6: Section Title Page No. 3.6 CYTOPATH
Page 7 and 8: Section Title Page No. 6.15.8 Blood
Page 9 and 10: instruments or possibly by splashin
Page 11 and 12: attend the Staff Health department
Page 13 and 14: 1.10 CENTRAL PATHOLOGY RECEPTION Ce
Page 15 and 16: 3. CELLULAR PATHOLOGY St Georges Ho
Page 17 and 18: investigations are necessary to ach
Page 19 and 20: 3.6.5 SAMPLE TRANSPORTATION INSTRUC
Page 21 and 22: Specimen Type Appropriate Specimens
Page 23 and 24: 3.7 MORTUARY SERVICES LOCATION - St
Page 25 and 26: 4. CLINICAL BLOOD SCIENCES: CHEMICA
Page 27 and 28: 4.6 BLOOD SPECIMENS Serum should be
Page 29 and 30: necessary for the assay of specific
Page 31 and 32: 4.19 IMMUNOSUPPRESSANT DRUG MONITOR
Page 33 and 34: Test Specimen and tube (colour) Bil
Page 35 and 36: Test Specimen and tube Gut Hormones
Page 37 and 38: Test Specimen and tube (colour) Ref
Page 39 and 40: 4.24 PAEDIATRIC REFERENCE RANGES TE
Page 41 and 42: 5. CLINICAL BLOOD SCIENCES: HAEMATO
Page 43 and 44: TEST SPECIMEN BOTTLE, MINIMUM VOLUM
Page 49: 5.6 REPORTS Copies of reports will
Page 53 and 54: 5. Date & time when specimen was ta
Page 55 and 56: situations where extended incubatio
Page 57 and 58: ) Broncho-alveolar lavage c) PCP 6.
Page 59 and 60: 6.13.9 OPHTHALMOLOGY SPECIMENS Cult
Page 61 and 62: 6.13.14 MRSA SCREENING Routine scre
Page 63 and 64: 6.13.25 BORDETELLA INVESTIGATION Pl
Page 65 and 66: HBsAg HIV antibody / antigen d) Nee
Page 67 and 68: 6.15.6 CONJUNCTIVAL SPECIMENS a) Vi
Page 69 and 70: 7. INFECTION CONTROL 7.1 CONSULTANT
Page 71 and 72: Matched serum and CSF samples shoul
Page 73 and 74: TEST/REQUEST POSSIBLE CLINICAL ASSO
Page 79 and 80: 10.1.1 TO SEND A SAMPLE WAIT UNTIL
Page 81 and 82: c) What happens if the carrier does

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