Evolution of Antibiotic Resistance-Printable Format - Teach ...

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Interpreting Data—Student Worksheet In this exercise, you will interpret real data on antibiotic resistance. These data were collected from a community in Finland from 1978 – 1993. The researchers collected data on the annual amount of antibiotics used in this community. They also collected samples of bacteria from young children with middle ear infections. They then examined the bacterial strains to see if they were susceptible to (killed by) or resistant to (not killed by) these antibiotics. The data given below are a measure of the amount of antibiotics used each year, and the percentage of the bacterial strains that were found to be resistant to the antibiotic (between 0 – 100%). Annual Percent Year Antibiotic Resistant Usage Strains 1978 0.84 0 1979 0.92 2 1980 1.04 29 1981 0.98 46 1982 1.02 45 1983 1.03 58 1984 0.95 61 1985 1.12 60 1986 1.06 49 1987 1.14 59 1988 1.21 58 1989 1.28 71 1990 1.32 84 1991 1.31 79 1992 1.27 78 1993 1.28 91 Instructions: Graph these data in two different graphs: A) antibiotic usage vs. year (antibiotic usage on the y-axis, year on the x-axis) and B) percent resistant strains vs. year (percent resistant strains on the y-axis, year on the x-axis). Using this information, answer the following questions: 1) Overall, what happened to the annual antibiotic usage in this community over the period of the study (did it increase, decrease, or stay the same)? ____________________
2) Overall, did the percentage of bacterial strains resistant to these antibiotics increase, decrease, or stay the same over this same time period? _______________________ 3) a) From these data, do you think these two factors (antibiotic usage and percentage of strains resistant to the antibiotics) are related? _______________ b) Do you think one of these factors was the cause of the other factor? _____________ c) If you do, which one? _________________ d) How might you be able to tell for sure? 4) In another study, also in Finland, researchers investigated the effect of greatly limiting the use of an antibiotic on a community (kids still got ear infections, but they now used a “wait and see” approach to see if the infection would clear up on its own). After antibiotic usage was greatly decreased, the percentage of bacterial strains that were resistant to this antibiotic was decreased by 50% (cut in half). What does this new information tell you?
Page 1 and 2: Evolution of Antibiotic Resistance
Page 3 and 4: Background Information on Antibioti
Page 5 and 6: a tolerance to the drug? Have they
Page 7 and 8: Overuse: ? It has been estimated th
Page 9 and 10: Scientists are also recommending th
Page 11 and 12: Part I: Define the Problem Activity
Page 13 and 14: Investigate Resistance to Antibioti
Page 15 and 16: Activity B) Research a Disease-Caus
Page 17 and 18: Research a Disease—Student Instru
Page 19 and 20: Part III. Investigate Reason for Pr
Page 21 and 22: What is Resistance to Antibiotics?
Page 23 and 24: Part IV. Investigate Reason for Pro
Page 25: Antibiotic Usage % Resistant Strain
Page 29 and 30: Christensen, D. Keeping bugs from p
Page 31: What is the Future of Antibiotics?

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