Handout 9 - Prions
Handout 9 - Prions
Handout 9 - Prions
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3/26/2006<br />
Treatment<br />
•Finally we have seen that PrPc expression is required for<br />
pathology.<br />
Chemicals affecting the endocytosis, exocytosis, intracellular<br />
trafficking and degradation of proteins and in particular PrPc<br />
may also be effective.<br />
Amphotericin for instance is reported to delay prion disease<br />
in hamsters (although it apparently has little effect in<br />
humans).<br />
• References:<br />
<strong>Prions</strong>.http://www.cartage.org.lb/en/themes/<br />
Sciences/LifeScience/GeneralBiology/Micr<br />
obiology/<strong>Prions</strong>Viroids/<strong>Prions</strong>/<strong>Prions</strong>.htm<br />
3/26/2006
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