ICP-MS

Chemical Warfare Agent Analysis by ICP-MS
H 3
Ner ve Agent s
C
G-Type V-Type
O
P
O C H
O C H
F H C
H 3
CH 3
CH 3
Soman (GD)
CH 3
H 3
C
O
P
F
O C
H
Sarin (GB)
CH 3
CH 3
O
O
P
N
CN
H C 3
O
P
F
O
N
TAbun (GA) Cycl osar in (GF)
VX
31 P Selective Detection
All these agents contain a P atom, so ICP-MS
can be used to identify and quantify the
concentration of agent, g , based on the
consistent (compound independent) response
for 31P. Nerve agents mostly decompose in the
environment to MPA (via EMPA, IMPA, CMPA…)
From Doug Richardson, Univ Cincinnati
Page 28
O
O
H C P O CH CH 3 2 3 C P
S
H 3
S
N
O
CH 3
CH 3
Russian VX (RVX)
ESAC April 2008