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Fellowship Grants NRSA F32

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<strong>Fellowship</strong> <strong>Grants</strong><br />

<strong>NRSA</strong> <strong>F32</strong><br />

Domenick “Tony” Prosdocimo, Ph.D.<br />

Post-Doctoral Fellow<br />

Laboratory of Mukesh Jain, MD<br />

PSP, Thursday 3/14/13


Experimental<br />

design<br />

Mentor’s advice<br />

Letters of<br />

recommendation<br />

Pilot data<br />

Goal setting<br />

<strong>Fellowship</strong> Toolbox:<br />

Where to look<br />

For fellowships<br />

Why a fellowship<br />

What budget<br />

can be used for<br />

Write a<br />

Compelling story<br />

Peer advice


The first steps toward a fellowship?<br />

1. Pre-doc: identify mentor with track record of training in your<br />

field of interest<br />

2. Post-doc:<br />

- Preliminary data.<br />

- Identify local and national collaborators<br />

- need 6-8 week block of time to write<br />

- appointment status – “post-doctoral scholar”<br />

- application deadlines<br />

3. A successful fellowship application focuses not only on the<br />

science, but also the training involved<br />

4. Acquire previously funded applications as a roadmap<br />

- email me, dap17@case.edu


• National Research Service Awards (<strong>NRSA</strong>)<br />

– F30 Predoctoral Awards for MD/PhD <strong>Fellowship</strong>s<br />

– F31 Predoctoral <strong>Fellowship</strong>s<br />

– <strong>F32</strong> Postdoctoral <strong>Fellowship</strong>s<br />

• K Awards<br />

– K01 Mentored Research Scientist Development Awd<br />

– K08 Mentored Clinical Scientist Development Award<br />

– K23 Mentored Patient-Oriented Research<br />

Career Development Award<br />

– K99/00 Pathway to Independence Award


Grantwriting Resources<br />

ScienceCareers.org<br />

Career Development Articles<br />

NIMH Grant Application Process<br />

http://www.nimh.nih.gov/researchFunding/grantprocess.cfm<br />

http://www.nimh.nih.gov/researchFunding/training.cfm<br />

FASEB <strong>Grants</strong>manship Training Program<br />

https://ns2.faseb.org/careerutilities/grantprg.htm<br />

Grant Application Writer’s Handbook, Reif-Lehrer<br />

See also http://casemed.case.edu/gradprog/


The NIH <strong>NRSA</strong> Ruth L Kirschstein<br />

F KIOSK<br />

http://grants1.nih.gov/training/F_files_nrsa.htm<br />

Stipend FY 2012<br />

Predoctoral $22,032<br />

Postdoctoral Years of Experience:<br />

0 $39,264<br />

1 $41,364<br />

2 $44,340<br />

3 $46,092<br />

Training Related Expenses<br />

Predoctoral Trainees: $4,200<br />

Postdoctoral Trainees: $7,850


Ruth L. Kirschstein National Research Service Awards (<strong>NRSA</strong>) for Individual<br />

Postdoctoral Fellows (Parent <strong>F32</strong>) (PA-10-110)National Institutes of HealthNational<br />

Center for Complementary and Alternative MedicineNational Cancer InstituteNational<br />

Center for Research ResourcesNational Eye InstituteNational Human Genome Research<br />

InstituteNational Heart, Lung, and Blood InstituteNational Institute on AgingNational<br />

Institute on Alcohol Abuse and AlcoholismNational Institute of Allergy and Infectious<br />

DiseasesNational Institute of Arthritis and Musculoskeletal and Skin DiseasesNational<br />

Institute of Biomedical Imaging and BioengineeringEunice Kennedy Shriver National<br />

Institute of Child Health and Human Development National Institute on Drug Abuse<br />

National Institute on Deafness and Other Communication DisordersNational Institute of<br />

Dental and Craniofacial ResearchNational Institute of Diabetes and Digestive and<br />

Kidney DiseasesNational Institute of Environmental Health SciencesNational Institute of<br />

General Medical SciencesNational Institute of Mental HealthNational Institute of<br />

Neurological Disorders and StrokeNational Institute of Nursing Research


The <strong>NRSA</strong> (F31, <strong>F32</strong>) success rate<br />

http://report.nih.gov/nihdatabook/index.aspx?catid=17


SA Application Preparation<br />

low the instructions:<br />

dividual <strong>Fellowship</strong> SF424 (R&R) Application Guide”<br />

1. Submission is three times per year<br />

(Apr 8, Aug 8, Dec 8)<br />

2. Grant needs routed internally first, application should be<br />

complete in full at least 1 week prior to submission dates<br />

3. Allow yourself 6-8 weeks to prepare<br />

4. This is a 3 year grant: proposal should fit accordingly<br />

5. It’s about the training as much as the science


Take a look at potential reviewers:<br />

Center for Scientific Review (CSR)<br />

http://www.csr.nih.gov/committees/rosterindex.asp<br />

Roster Index for <strong>Fellowship</strong> Study Section<br />

http://public.csr.nih.gov/StudySections/<strong>Fellowship</strong>/Pages/default.aspx<br />

Physiology and Pathobiology of Cardiovascular and<br />

Respiratory Systems [ F10A ]


• Reviewers are:<br />

– Busy<br />

– Overworked<br />

Write for the Reviewers<br />

– May not be as<br />

knowledgeable about<br />

the details<br />

Typically, you’ll receive three reviewers:<br />

-each reviewer scores your grant on a 1-9 scale prior to study section.<br />

-the average gives an impact score<br />

The day your study section meets:<br />

-all reviewers of the study section will have access to the impact<br />

scores as well as the grant<br />

-typically, best scored grants will be discussed first<br />

-on average, each grant gets discussed for only 10 minutes<br />

-impact scores could change following discussion<br />

-final impact scores are translated into a percentile


Reviewer 1<br />

Reviewer 2<br />

Reviewer 3


The Application:<br />

Online: grants.gov - SF 424 (R&R)<br />

All subsequent sections are submitted as .pdf into this online<br />

submission form<br />

1. Project Summary / Abstract<br />

2. Project Narrative: 2-3 sentence paragraph summarizing<br />

your application in layman terms<br />

3. References Cited<br />

4. Facilities & Other Resources<br />

5. Equipment<br />

6. List of Referees: (identify 3 referees early)<br />

- 3 letters of reference submitted by the referee through<br />

eRA commons, you simply list the individuals name and<br />

affiliation.


The Application cont:<br />

7. Letters of Support: (identify potential collaborators<br />

early)<br />

- What techniques are outside the scope of your lab’s<br />

expertise<br />

- Be explicit in stating you will learn these techniques<br />

first-hand in your collaborators’ lab<br />

- remember, it’s more about the training than the<br />

science<br />

- be prepared to write these letters yourself and simply<br />

have your collaborator sign them


The Application cont:<br />

8. Statement by the mentor: (Critical)<br />

- A good letter should include:<br />

- Applicant accomplishments<br />

- Brief statement about applicant, undergrad and post-grad<br />

studies<br />

- how mentor came to know applicant<br />

- genesis of current application<br />

- current collaborations applicant has with other lab members<br />

- Mentor Training Record<br />

- brief background of mentor<br />

- list of past and present mentees (where are they now)<br />

- Research Training Plan for the Applicant<br />

- how often will mentor meet with applicant<br />

- present at local and national meetings<br />

- Relationship of training to career goals<br />

- how will the current application aid in developing an<br />

independent line of investigation


The Application cont:<br />

9. Biosketch:<br />

- Applicant<br />

- Personal statement, position and honors,<br />

Publications<br />

- Undergrad and post-graduate grades<br />

- Mentor


Get Started: The Research Idea<br />

A strong research idea should pass the “so what” test.<br />

What is the benefit of answering your question?<br />

Who will it help and how?<br />

If you cannot make a definitive statement about<br />

the purpose of your research, it is unlikely to be funded.


The Application cont:<br />

10. Specific Aims Page (1 page):<br />

- Brief overview/background<br />

- Hypothesis<br />

- Aims<br />

- helpful to include cartoon of hypothesis and aims


Specific Aims<br />

Goal - make the reviewer want to read more<br />

Make sure you:<br />

Provide a rationale—where did hypothesis come from?<br />

why is this a strong idea? is it novel?<br />

Have objectives that are measurable and highly focused<br />

Have aims that are feasible in technique, time and money<br />

-remember, this is a three year grant<br />

http://www.theresearchassistant.com/tutorial/2-1.asp


The Application cont:<br />

11. Research Strategy (6 pages):<br />

- Background and Significance<br />

- Approach / Preliminary Results<br />

- Aims<br />

- Rationale for subaims and proposed studies<br />

- Interpretation, Limitations, and Future Directions<br />

- Methods<br />

- Statistics


Questions thus far?


12. Use of Vertebrate animals:<br />

The Application cont:<br />

13. Select Agent Research:<br />

- are there hazardous or biological agents to be used to carry out<br />

proposed studies?<br />

14. Resource Sharing Plan<br />

- will the application result in the development of a new agent /<br />

mouse strain – NIH wants us to share<br />

15. Respective Contributions<br />

16. Selection of sponsor and institution<br />

- Why did you join the lab<br />

- how will the current application allow you to develop and<br />

independent line of investigation<br />

17. Responsible Conduct of Research


The Application cont:<br />

18. Goals for <strong>Fellowship</strong> Training and Career<br />

- short and long term goals<br />

- state how the current application will position you for Kgrant,<br />

R01 / independent line of investigation<br />

19. Activities Planned under this award<br />

- dedicated percent effort<br />

- what weekly research seminars will you attend<br />

- national meetings<br />

20. Doctoral Dissertation<br />

- 2 page summary of dissertation if applicable


Reviewer 1<br />

Reviewer 2<br />

Reviewer 3


Questions?

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