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Application Areas of Nanospray-HPLC- Chip/MS

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Enhancements in Time-<strong>of</strong>-Flight<br />

New Acquisition Technology Increasing Resolving Power<br />

O<br />

FIA, 2 scans/sec (6713 transients/scan)<br />

2 IRM averaged over five scans<br />

Page 16<br />

O<br />

O<br />

OH<br />

Butyl paraben<br />

[M+H] + 195.10157<br />

Methyl 5-acetylsalicylate<br />

[M+H] + 195.06519<br />

HO<br />

O<br />

8 bit – 1 GHz<br />

Analog Digital<br />

Converter<br />

O<br />

195.088679<br />

6,100 Resolving<br />

Power (FWHM)<br />

195 195.02 195.04 195.06 195.08 195.1 195.12 195.14 195.16 195.18 195.2<br />

Counts vs. Mass-to-Charge (m/z)

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