of H3 loop - Accelrys

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6 How? Discovery Studio and Pipeline Pilot • Protocols (Calculations) can be run in Pipeline Pilot or Discovery Studio 2.0
7 WebPort WebPort (web (web access) access) Pipeline Pipeline Pilot Pilot (Pro or Lite ) (Pro or Lite ) Chemistry Biology Materials <strong>Accelrys</strong> ® Discovery Studio ISV ISV Client Client (e.g., (e.g., Spotfire) Spotfire) Materials Materials Studio Studio Client Client Client Integration Layer S c i i T e g i i c P l l a t t f f o r r m Accord Accord Discovery Discovery Studio Studio Client Client Tool Integration Layer Data Access Layer Cmd-Line Statistics Reporting ISV Tools Discovery Studio Accord Accord Clients Clients IDBS Oracle ISIS Databases Isentris
Page 1 and 2: Life Science Webinar Series Antibod
Page 3 and 4: 3 Why Antibodies? • Critical elem
Page 5: 5 The Antibody Structure (cnt’d)
Page 9 and 10: 9 Loop Refinement Method: Template
Page 11 and 12: 11 Example: Template based refineme
Page 13 and 14: 13 Summary: • The “Model Antibo
Page 15 and 16: 15 Side-Chain Refinement using ChiR
Page 17 and 18: 17 Loop Refinement using Looper •
Page 19 and 20: 19 Looper Methodology • Next, Loo
Page 21 and 22: 21 MODELER • Best Homology model:
Page 23 and 24: 23 Summary: • Success of LOOPER s
Page 25 and 26: 25 Acknowledgements • Velin Spass

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