of H3 loop - Accelrys
of H3 loop - Accelrys
of H3 loop - Accelrys
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8<br />
How? (cnt’d)<br />
• Procedure for Antibody Modeling:<br />
1. Sequence based search for homolog<br />
2. Sequence Alignment<br />
3. Building <strong>of</strong> Homology Model<br />
4. Analysis <strong>of</strong> Homology Model<br />
5. Identification <strong>of</strong> CDR <strong>loop</strong>s<br />
6. Refinement <strong>of</strong> the <strong>loop</strong>s<br />
– Template<br />
– de novo
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