28 Wilson's Disease

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Back to our patient…. Listed as 1A for Liver Transplant Transferred to ICU Started on Penicillamine Developed ARF Transitioned to Trientine Improved LFTs and mental status Discharged home after 11d admission
Objectives • Review the differential diagnosis of emesis • Review the biologic role of copper • Compare Wilson’s disease to Menke’s disease • Review the symptoms, diagnosis and treatment of Wilson’s disease • Briefly review complications associated with liver transplant
Page 1 and 2: Morning Report Chief Residents July
Page 3 and 4: • 1 wk of RUQ pain, NV, fatigue
Page 5 and 6: Physical Exam Vitals: T36.6 HR67 RR
Page 7: Wilson’s Disease • AR defect in
Page 10: 2 diseases involving Cu transport W
Page 13 and 14: Fatty infiltration and portal fibro
Page 15 and 16: Our patient’s slit lamp exam
Page 18 and 19: Diagnosis • Coomb’s negative he
Page 20 and 21: • 2 phases - Removal of copper Tr
Page 22 and 23: • Trientine - Cu chelator Chelato
Page 24 and 25: Dietary Recommendations • Limit i
Page 26 and 27: Liver Transplant Complications •

28 Wilson's Disease

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