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M.R. Noori-Daloii Academic Experience and Research Activities:

M.R. Noori-Daloii Academic Experience and Research Activities:

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• Designing a national laboratory research medical (molecular) biotechnology (NLRMB).<br />

• Synthesis <strong>and</strong> sequencing of complementrary DNA (cDNA) from human Placental bfGF (FGF).<br />

• Production of alkaloid chemotypes using genetic techniques <strong>and</strong> Protoplast Culture of some Species of Vinca<br />

<strong>and</strong> Rahazya genera of Apocynaceae family.<br />

• Genetics investigation of Methicillin resistant (met r ) <strong>and</strong> Vancomycin resistant (Van r ) S. aureus isolates.<br />

• Quantitative <strong>and</strong> qualitative studies of pigmented compounds in different species of Saffron <strong>and</strong> in Culture of<br />

isolated cells (as a national project).<br />

• Investigation of chromosomal abnormalities in different tissues of patients with Suspected Chromosomal<br />

syndromes <strong>and</strong> cancer using the technique of molecular. cytogenetics, FISH.<br />

• Study of genetic diversity <strong>and</strong> virulence variation of the Russian Wheat aphid;<br />

Diuraphisnoxia (Homoptera: Aphididae) populations in Iran.<br />

• Microbial, biochemical <strong>and</strong> genetical investigation of cellulolytic enzyme from three Iranian Cellulomons<br />

Species.<br />

• Molecular Genetic of RP(Retinitis Pigmentosa)in Iranian Populations (as a national project).<br />

• Frequency of the microdeletion 22q 11 in Iranian newborn infants with congenital heart disease.<br />

• Comparison between ARG(ABL-2) protein expression in Follicular <strong>and</strong> diffuse large B-Cell Lynopoma.<br />

• Delection of polymorphism <strong>and</strong> expression rate of 14-3-3 <strong>and</strong> synuclein genes in Pripheral blood lymphocytes<br />

of Schizophrenic patients for genetic detection <strong>and</strong> drug therapy.<br />

• A Molecular Genetics Survey of Esophageal Squamous Cell Carcinoma (SCC).<br />

• Molecular studies on the role of siRNA towards the gene therapy of Schizophernia (as a national project).<br />

• Detection of polymorphism <strong>and</strong> the rate of µ- opioid receptor <strong>and</strong> its subtype<br />

(M1,M1a,M1b,M1c,M1d,M1e,M1f) in peripheral blood lymphocyte of addicted people to opiate.<br />

●Investigation of Genetic polymorphism for G6PD, TNFa <strong>and</strong> NOS2 in Iranian G6PD deficiency patients <strong>and</strong> its<br />

correlation with Malaria.<br />

●Effect of Quercetin ,a bioflavonoid on KAI-1 , a metastasis suppressor gene in Prostate Cancer.<br />

● Study of association between TGF-β1(codon10) <strong>and</strong> TGF-β1(codon25) gene polymorphisms <strong>and</strong> GVHD in<br />

bone marrow transplant patients.<br />

●Effect of quercetin, abioffavonoidon KAI-1,a metastasis supperesor gene prostate cancer.<br />

●Study of association between CTLA-4 gene pdymorphism <strong>and</strong> Susceptbility to Multiple Sclerosis in 150 Iranian<br />

MS patients.<br />

●Differential analysis of miRNA reservoir of hair follicle Dermal papilla cells Balding <strong>and</strong> nonbalding areas of<br />

<strong>and</strong>rogenetic Alopecia subjects by miRNA Amplification profiling (miRNP) Method.<br />

● High-throughput differential gene expression analysis in diabetic nephropathy type 2 patients as compared<br />

with the control group using Suppression Subtractive Hybridization(SSH).<br />

• Investigation the inhibitory effect of Soy-derived Genistein on the metastasis of A549 Lung cancer cell line.<br />

• Genetic linkage analysis to identify the loci involved in the Autosomal Recessive Non-syndrome-hearing<br />

Loss(ARNSHL) in the Iranian population.<br />

• Genetic linkage analysis of the Iranian patients with autosomal recessive non-syndromic hearing<br />

loss(ARNSHL).<br />

• Genetic Linkage study <strong>and</strong> analysis to Identify the loci Involved in the Autosomal Recessive Non-Syndromic<br />

Hearing Loss (ARNSHL)in the south- Khorasan province of Iran.<br />

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