Diversion and Abuse of Buprenorphine: A Brief Assessment of ...
Diversion and Abuse of Buprenorphine: A Brief Assessment of ...
Diversion and Abuse of Buprenorphine: A Brief Assessment of ...
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Hypothesis 6: Significant levels <strong>of</strong> buprenorphine diversion <strong>and</strong> abuse are occurring in<br />
Vermont.<br />
Relevant Information: Dr. M<strong>and</strong>ell first began to receive reports <strong>of</strong> buprenorphine abuse in early<br />
2005. Because the reports were entirely anecdotal, he has used the limited data available to him –<br />
as well phone consultations with prescribing physicians <strong>and</strong> other sources <strong>of</strong> information – to try<br />
to clarify the situation.<br />
Peter Lee <strong>of</strong> the Vermont SSA reported that some buprenorphine diversion <strong>and</strong> abuse is<br />
occurring in Vermont. Mr. Lee confirmed that he has received anecdotal reports <strong>of</strong><br />
buprenorphine tablets being crushed <strong>and</strong> injected. However, he described this as “horizontal”<br />
diversion within the addicted population – who rent pills for pill checks, for example, or sell part<br />
<strong>of</strong> their supply <strong>of</strong> buprenorphine to a friend who cannot access treatment – rather than “vertical”<br />
diversion into the general population.<br />
An <strong>of</strong>ficial <strong>of</strong> the Vermont Department <strong>of</strong> Corrections reported that buprenorphine was being<br />
smuggled into the State’s correctional institutions, <strong>and</strong> said that the amount exceeded that <strong>of</strong><br />
methadone or oxycodone. He also described buprenorphine as easy to obtain on the street, as<br />
compared to oxycodone, which he described as not widely used in Vermont (however, this<br />
anecdotal report is not consistent with the DAWN medical examiner data).<br />
Several other corrections <strong>of</strong>ficials suggested that buprenorphine was being smuggled into<br />
correctional facilities to sell to inmates who wanted to “get high” or to help inmates withdraw<br />
from heroin. Officials said some inmates who were addicted to heroin reported stockpiling<br />
buprenorphine prior to their incarceration.<br />
On the other h<strong>and</strong>, Gretchen Feussner <strong>of</strong> DEA’s Office <strong>of</strong> <strong>Diversion</strong> Control confirmed that the<br />
DEA field <strong>of</strong>fice for Vermont had not received any reports <strong>of</strong> buprenorphine diversion.<br />
The head <strong>of</strong> the Vermont State Police Laboratory reported that, in all <strong>of</strong> 2004 <strong>and</strong> 2005,<br />
buprenorphine had been seized in only eight cases. In every case, the formulation involved was<br />
Suboxone. Five seizures involved one tablet each, one seizure involved two tablets, <strong>and</strong> one<br />
involved three tablets. Thus, the Vermont State Police laboratory does not consider diversion <strong>of</strong><br />
buprenorphine to be a significant problem at this time.<br />
Multiple datasets were examined in an effort to determine whether <strong>and</strong> to what degree<br />
buprenorphine was cited as either a primary or secondary drug <strong>of</strong> abuse by individuals entering<br />
addiction treatment in Vermont. While SAMHSA’s Drug <strong>Abuse</strong> Warning Network (DAWN)<br />
provides data on adverse events associated with a large number <strong>of</strong> drugs, no hospital emergency<br />
departments in Vermont report to DAWN. Boston is the closest metropolitan area with<br />
reporting hospitals. Interestingly, Boston also reports more emergency department visits related<br />
to buprenorphine than any other metropolitan area in the DAWN system (Exhibit 7).<br />
Results <strong>of</strong> the Vermont Case Study<br />
15