REENA MEHRA MD, MS, FCCP - Case Western Reserve University ...

Updated: November 14, 2011
2006-2011 K23 Mentored Patient-Oriented Clinical Research Career Development Award
NIH/NHLBI HL079114
Title: Oxidative Stress in Sleep Apnea and Cardiac Disease
The goal is to assess changes in oxidative stress and intermediate cardiovascular
measures including vascular stiffness in patients with sleep-disordered breathing who
receive CPAP and sham CPAP in a randomized parallel design study.
Mehra (PI)
June- Jan 2011 Clinical Translational Science Collaborative Small Pilot Grant
Vascular Compliance and Inflammation in Sleep Apnea and Cardiac Disease
Aims include investigating the relationships of SDB and measures of vascular stiffness
(pulse wave analysis and pulse wave velocity) obtained via radial and carotid-femoral
arterial applanation tonometry.
Mehra (PI)
2005-2009 Association of Subspecialty Professors (ASP)-CHEST Foundation of the American
College of Chest Physicians-Geriatrics Development Research Award T. Franklin
Williams Award
Title: Sleep Disordered-Breathing and Cardiac Arrhythmia Associations with Alcohol
Use and Dependence in Elderly Men
Evaluating the following in a well-characterized elderly male cohort with rigorous data
collection (MrOS Sleep Study): 1.) the relationship between alcohol use and sleepdisordered
breathing; 2.) alcohol use and nocturnal cardiac arrhythmias; and 3.) the
association of synergistic effects of alcohol use and sleep-disordered breathing with
nocturnal cardiac arrhythmias compared to either exposure alone.
Mehra (PI)
2005-2008 American Heart Association
National Scientist Development Award
Title: Oxidative Stress in Sleep Apnea and Cardiac Disease
The goal is to assess changes in oxidative stress and echocardiographic measurements in
patients with sleep-disordered breathing who receive CPAP and sham CPAP in a
randomized crossover design as an ancillary study to the Effects of Sleep Apnea
Treatment on Metabolic Syndrome study.
Mehra (PI)
2006 K12 Multidisciplinary Clinical Research Training Program
Title: Oxidative Stress in Sleep Apnea and Cardiac Disease
The goal is to assess changes in oxidative stress, echocardiographic measurements and
endothelial dysfunction as assessed by brachial reactivity in patients with sleepdisordered
breathing who receive CPAP and sham CPAP in a randomized parallel design
study.
Mehra (PI)
2006-2007 Women Faculty of the School of Medicine, Case School of Medicine
Women Faculty School of Medicine Career Development Award
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