Role of OT in Maternal Behavior
Role of OT in Maternal Behavior
Role of OT in Maternal Behavior
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
<strong>Maternal</strong> Aggression<br />
• Levels <strong>of</strong> aggression are l<strong>in</strong>ked to anxiety<br />
o rats selectively bred for high anxiety-related<br />
behavior (HAB) are more aggressive than rats bred<br />
•<br />
for low anxiety-related behavior (LAB).<br />
Oxytoc<strong>in</strong> release with<strong>in</strong> the PVN and central nucleus <strong>of</strong><br />
the amygdala (CeA) is higher <strong>in</strong> HAB than <strong>in</strong> LAB dams,<br />
and blockade <strong>of</strong> <strong>OT</strong>R by bilateral <strong>in</strong>fusion <strong>of</strong> an <strong>OT</strong>R<br />
antagonist directly <strong>in</strong>to the PVN or CeA reduced<br />
aggression <strong>in</strong> HAB dams, whereas <strong>in</strong>fusion <strong>of</strong> synthetic<br />
oxytoc<strong>in</strong> <strong>in</strong>to the PVN <strong>in</strong> LAB dams tended to <strong>in</strong>crease<br />
maternal aggression
Change language