Evotec Munich

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Complete Proteome Analysis
Large-scale, label-free quantification of proteins
Recent advances in sample processing and mass spectrometry enables fast
identification of ~7,000 proteins per cell line
In a comparative proteomics analysis co-published by Evotec Munich scientists,
more than 10,000 proteins were identified across 11 cell lines (this corresponds to
51% of the human genes)
Comparisons with deep sequencing data indicate this
covers most of the proteome expressed in human cancer
cell lines
Proteome profiling has thus reached a level of
comprehensiveness similar to mRNA profiling
Geiger et al, 2012,, MCP, 11, M111 014050
Schaab et al., 2012, MCP, 11, M111 014068