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Regioselective Reductive Cross-Coupling Reaction

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1.4. Imine<br />

(Micalizio et.al. Angew. Chem. Int. Ed. 2007, 46, 391.) aza-Pauson Khand-like annulation reaction for the<br />

synthesis of tetrasubstituted γ-lactams<br />

(Micalizio et.al. Chem Commun. 2010, 46, 3336.)<br />

carbometalation process is irreversible.<br />

9/16

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