S. aureus

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Risk for S. aureus Infection • Measured 1-year risk of MRSA infection following detection of nasal colonization – 4 hospitals over 4.5 years with 211,339 episodes • 1-year risk of MRSA infection was 11.8% for nasally colonized persons • 1-year risk of MRSA infection was 0.7% for non-colonized persons D Ridgway et al. IDSA meeting, 2011 • Suggests 1-year risk of MSSA infection is 2.9% for nasally colonized persons
Review of Mupirocin Decolonization • Nasal carriage of S. aureus is a defined risk factor for subsequent infection in patients • 8 studies compared mupirocin with placebo or with no treatment: Statistically significant reduction in the rate of S. aureus infection associated with intranasal mupirocin (RR 0.55, 95% CI = 0.43 to 0.70) M van Rijen et al. Cochrane Database of Systematic Reviews 2008, Issue 4. Art.No.:CD006216.
Page 1 and 2: The Skin Microbiome - Clinical Labo
Page 3 and 4: Objectives • Review the relevance
Page 5 and 6: Skin Ecology - Dominance • Propio
Page 7 and 8: Microbiome of the Nose • S. aureu
Page 9: Risk for S. aureus Infection • Sy
Page 13 and 14: CDC Surveillance (2005) • Prospec
Page 15 and 16: US Infection Mortality 2005 FR DeLe
Page 17 and 18: Percent Positive on Admission 25.0
Page 19 and 20: NorthShore MRSA Program Began on Au
Page 21 and 22: Includes all admissions (Community
Page 23 and 24: Medical and Economic Outcome • Ex
Page 25 and 26: Cluster Randomized Trial of ICU: De
Page 28 and 29: Changing Prevalence of S. aureus in
Page 30 and 31: Results of Preoperative Screening f
Page 32 and 33: Prospective, Randomized Trial of S.

S. aureus

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