S. aureus

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Veterans Administration Healthcare System (153 Hospitals) • Reported 21-month results of all admission screening for MRSA based on 1,312,840 admissions covering 8,318,675 patient days • 45% reduction in MRSA disease in non-ICU patients (P = 0.001) throughout the system • 62% reduction in MRSA disease for ICU patients (P < 0.001) – 2 year baseline in ICU patients had no change in disease R Jain et al. NEJM 364:1419-30, 2011 • Testing primarily (92%) with rtPCR methods
Cluster Randomized Trial of ICU: Demonstrated non-Utility of Culture • Assessed VRE and MRSA surveillance plus enhanced barrier precautions in the ICU • 5,434 admissions to 10 intervention ICUs, and 3,705 to 8 control ICUs over 6 months – Centralized, broth enriched culture used for testing • Incidence of colonization or infection with MRSA or VRE per 1000 patient-days at risk did not differ significantly (P = 0.35) • Mean (±SD) number of days from when surveillance swab obtained until it was reported was 5.2±1.4 – 41% of patient days captured after reporting WC Huskins et al. NEJM 364:1407-18, 2011
Page 1 and 2: The Skin Microbiome - Clinical Labo
Page 3 and 4: Objectives • Review the relevance
Page 5 and 6: Skin Ecology - Dominance • Propio
Page 7 and 8: Microbiome of the Nose • S. aureu
Page 9 and 10: Risk for S. aureus Infection • Sy
Page 11 and 12: Review of Mupirocin Decolonization
Page 13 and 14: CDC Surveillance (2005) • Prospec
Page 15 and 16: US Infection Mortality 2005 FR DeLe
Page 17 and 18: Percent Positive on Admission 25.0
Page 19 and 20: NorthShore MRSA Program Began on Au
Page 21 and 22: Includes all admissions (Community
Page 23: Medical and Economic Outcome • Ex
Page 28 and 29: Changing Prevalence of S. aureus in
Page 30 and 31: Results of Preoperative Screening f
Page 32 and 33: Prospective, Randomized Trial of S.

S. aureus

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