4-METHYLPENTAN-2-OL CAS N°: 108-11-2

OECD SIDS
4-METHYLPENTAN-2-OL
1. GENERAL INFORMATION ID: 108112
DATE: 4.07.2006
during methyl isobutyl ketone (MIBK) production or directly
by hydrogenation of MIBK.
MIBC is primarily used (~70%) in the production of lube oil
additives, specifically zinc dialkyldithiophosphate, for
antiwear and corrosion inhibitors. The second largest use
of MIBC (~20%) is as a flotation frother for treating copper
ores and coal (Bizzari, 1999). In mining frother
applications, MIBC is used in the ppm range, with usual
concentrations less than 1000 ppm and in many cases in the
hundreds of ppm range (100 - 600 ppm). The remaining
production is primarily for its use as an additive to
surface coatings as a solvent to maintain binder softness
until the binder fuses.
09.12.2005 (2)
1.7.1 DETAILED USE PATTERN
1.7.2 METHODS OF MANUFACTURE
Origin of substance : Natural origin
Type :
Remark : MIBC is produced either as a recovered coproduct during
methyl isobutyl ketone (MIBK) production or directly by
hydrogenation of MIBK. MIBK is produced from acetone in a
3-step reaction. The first step involves the aldol
condensation of two molecules of acetone in liquid phase to
diacetone alcohol. Diacetone alcohol is then dehydrated
under acidic conditions to mesityl oxide. Lastly, mesityl
oxide is hydrogenated using a palladium catalyst to MIBK.
09.12.2005 (2)
1.8 REGULATORY MEASURES
1.8.1 OCCUPATIONAL EXPOSURE LIMIT VALUES
Remark : The ACGIH TLV-TWA for MIBC is 25 ppm (104 mg/m3) and the
TLV-STEL is 40 ppm (167 mg/m3). The German MAK value is 25
ppm.
19.04.2005
1.8.2 ACCEPTABLE RESIDUES LEVELS
1.8.3 WATER POLLUTION
1.8.4 MAJOR ACCIDENT HAZARDS
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